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hypothetical_protein_H012_gp708

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

hypothetical_protein_H012_gp708__YP_007354193__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354193 ↗
Protein ID:
hypothetical_protein_H012_gp708
Kingdom:
euk

Quality

79.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 20-122_519-533
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF11443.14 best DUF2828 52.6 4.80e-14 99.2% 26.2%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vwaA03 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 53.0 3.94e-01 87.3% 36.6%
4j8sA00 1.25.40.840 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › CCR4-NOT transcription complex subunit 1 TTP binding domain 0.64 53.0 4.57e-01 87.3% 61.1%
2b6cA01 1.20.1660.10 Mainly Alpha › Up-down Bundle › ARM repeat fold › Hypothetical protein (EF3068) 0.64 50.0 5.04e-01 83.1% 100.0%
3t8vA05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.62 49.0 3.61e-01 85.6% 60.8%
2q7fA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 42.0 3.57e-01 78.8% 43.3%
1t9kA01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.59 49.0 4.69e-01 91.5% 88.6%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 40.0 3.99e-01 76.3% 65.9%
2pm6A00 1.25.40.1030 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 40.0 2.89e-01 87.3% 23.5%
2xqyA02 1.20.58.1340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 44.0 4.17e-01 81.4% 95.1%
3o4zA02 1.25.40.720 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tel2 C-terminal domain 0.58 51.0 4.40e-01 100.0% 95.9%
4kvmA01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 48.0 3.13e-01 89.8% 22.9%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 48.0 4.16e-01 94.9% 78.5%
1szhA02 1.10.150.370 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Caenorhabditis elegans Her-1, C-terminal domain 0.56 35.0 4.07e-01 87.3% 90.2%
1nktA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 49.0 3.71e-01 97.5% 80.1%
3k9iA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 39.0 4.10e-01 82.2% 82.5%
4m7cB00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.54 46.0 3.92e-01 94.1% 88.4%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.54 41.0 3.83e-01 82.2% 94.8%
4xi0F00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 42.0 3.72e-01 87.3% 68.5%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 32.0 3.38e-01 81.4% 68.6%
1e7uA05 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.52 46.0 3.94e-01 97.5% 100.0%
1ouvA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 41.0 3.25e-01 87.3% 46.8%
3mkrA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 41.0 3.13e-01 89.0% 45.7%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3333939 109.16.1.2 alpha superhelices › Repetitive alpha hairpins › TROVE domain-like › TROVE domain-like › DUF2828 0.86 71.0 4.99e-01 100.0% 30.4%
3424971 109.16.1.2 alpha superhelices › Repetitive alpha hairpins › TROVE domain-like › TROVE domain-like › DUF2828 0.84 70.0 5.06e-01 86.4% 39.7%
3599766 109.26.1.0 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains 0.70 57.0 3.49e-01 87.3% 15.6%
3247942 109.16.1.2 alpha superhelices › Repetitive alpha hairpins › TROVE domain-like › TROVE domain-like › DUF2828 0.69 66.0 4.88e-01 100.0% 50.4%
3275755 109.4.1.435 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RICTOR_N 0.68 53.0 5.07e-01 83.9% 100.0%
3244944 109.4.1.1136 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_PRP39_N 0.65 52.0 4.00e-01 87.3% 37.5%
3260138 109.4.1.89 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Drf_FH3,Drf_GBD 0.63 50.0 3.64e-01 87.3% 41.4%
3822594 3932.1.1.0 alpha bundles › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain 0.61 41.0 4.71e-01 85.6% 100.0%
3650959 109.4.1.1256 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.61 46.0 3.80e-01 78.8% 44.8%
3676536 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.61 55.0 4.86e-01 100.0% 80.0%
3320381 109.4.1.1261 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long 0.59 48.0 4.37e-01 87.3% 78.1%
3457892 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 46.0 4.21e-01 87.3% 62.3%
3937578 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 53.0 4.66e-01 100.0% 74.3%
3643338 109.4.1.1292 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3 0.58 44.0 4.13e-01 87.3% 63.3%
3827125 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 46.0 4.02e-01 87.3% 71.7%
3936257 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 48.0 3.69e-01 99.2% 61.5%
1086916 109.4.1.109 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 0.53 42.0 3.99e-01 87.3% 75.5%
3828594 109.4.1.1365 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2, TPR_24 0.52 42.0 4.44e-01 94.9% 100.0%
3712667 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.51 39.0 3.80e-01 82.2% 94.1%
D2 high residues 126-198
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF11443.14 best DUF2828 40.8 1.80e-10 97.3% 13.1%
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2wh5A00 1.20.80.10 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.64 34.0 3.20e-01 79.5% 41.1%
1wizA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.62 37.0 3.68e-01 89.0% 55.7%
3kttB01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.61 45.0 3.13e-01 79.5% 25.1%
3l9tA01 1.10.1240.70 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.58 37.0 3.59e-01 86.3% 57.8%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 48.0 4.20e-01 94.5% 69.6%
5vjcA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.57 45.0 3.10e-01 100.0% 24.0%
2fd5A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 49.0 4.09e-01 98.6% 75.0%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.56 41.0 4.50e-01 95.9% 100.0%
4j8sA00 1.25.40.840 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › CCR4-NOT transcription complex subunit 1 TTP binding domain 0.56 45.0 3.46e-01 90.4% 39.4%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.56 41.0 3.95e-01 97.3% 68.2%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.55 49.0 3.83e-01 100.0% 53.5%
2yqzA02 1.10.8.900 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.54 37.0 3.91e-01 100.0% 77.9%
2cwoA01 1.20.58.1200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RNA silencing suppressor P21, N-terminal domain 0.54 45.0 4.57e-01 98.6% 94.6%
3kp9A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.53 44.0 3.57e-01 98.6% 59.3%
1u5tB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 43.0 4.10e-01 90.4% 97.6%
4huqS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.51 44.0 3.50e-01 100.0% 84.1%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.51 46.0 3.68e-01 100.0% 97.9%
2hgkA01 1.20.1440.40 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › YqcC-like 0.51 40.0 3.59e-01 100.0% 60.0%
3u3gA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 43.0 3.61e-01 100.0% 52.1%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3278726 101.1.1.282 alpha arrays › HTH › HTH › Three-helical HTH › DUF222 0.63 45.0 3.74e-01 75.3% 57.6%
4939077 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.57 43.0 3.11e-01 80.8% 67.0%
3299317 604.1.1.96 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Bap31 0.57 50.0 4.24e-01 100.0% 87.2%
3483996 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 48.0 4.27e-01 100.0% 84.5%
3461381 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 48.0 3.96e-01 100.0% 62.1%
3397167 1065.1.1.1 alpha bundles › SPX domain › SPX domain › SPX domain › SPX 0.54 47.0 3.42e-01 100.0% 63.6%
3727188 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 46.0 3.80e-01 98.6% 55.0%
3215252 109.4.1.1134 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_INTS8_3 0.53 45.0 2.87e-01 100.0% 46.5%
5078097 604.1.1.265 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › HepT-like 0.51 44.0 3.74e-01 100.0% 74.6%
3928003 192.4.1.0 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.51 44.0 3.78e-01 100.0% 73.3%
3867778 3736.1.1.0 alpha superhelices › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 0.50 40.0 2.50e-01 94.5% 13.8%
5039732 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.50 42.0 3.72e-01 97.3% 87.6%
D3 high residues 296-498
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25043.1 best DUF7788 201.4 1.70e-59 91.6% 84.6%
D4 medium residues 213-295
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF11443.14 best DUF2828 32.7 5.30e-08 100.0% 15.3%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4f0cA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 41.0 3.50e-01 79.5% 80.4%
1pn9B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 41.0 3.58e-01 80.7% 80.0%
4l9mA02 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.54 42.0 3.09e-01 86.7% 65.5%
3ay8A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 40.0 3.47e-01 80.7% 76.5%
3k62A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.53 45.0 2.92e-01 95.2% 22.0%
1r5aA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 40.0 3.46e-01 83.1% 69.1%
2ijeS00 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.52 41.0 2.95e-01 83.1% 53.6%
2yv9B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 43.0 3.73e-01 92.8% 82.1%
3h37A02 1.10.110.30 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › 0.50 42.0 4.21e-01 100.0% 94.2%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3247942 109.16.1.2 alpha superhelices › Repetitive alpha hairpins › TROVE domain-like › TROVE domain-like › DUF2828 0.94 76.0 5.06e-01 100.0% 25.6%
3424971 109.16.1.2 alpha superhelices › Repetitive alpha hairpins › TROVE domain-like › TROVE domain-like › DUF2828 0.86 69.0 4.60e-01 100.0% 24.1%
3391100 109.1.1.6 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 0.56 42.0 3.65e-01 80.7% 80.0%
3712980 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 44.0 3.12e-01 88.0% 50.7%
3843701 129.1.1.27 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Speriolin_C 0.55 40.0 3.32e-01 98.8% 41.9%
3398947 109.1.1.6 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 0.54 40.0 3.46e-01 80.7% 77.5%
3965844 589.1.1.2 alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › Porin chaperone SurA, peptide-binding domain › SurA_N_3 0.53 39.0 3.16e-01 75.9% 57.5%
4966165 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.53 46.0 3.73e-01 97.6% 57.3%
4661231 109.1.1.1 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C 0.52 39.0 3.42e-01 80.7% 82.3%
4013416 3924.1.1.0 alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 0.52 41.0 2.91e-01 90.4% 76.3%
3596966 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.51 40.0 2.99e-01 86.7% 43.6%
3255796 109.6.1.3 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N 0.50 42.0 3.49e-01 100.0% 66.7%