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hypothetical_protein_MIMI_gp0179
Euk-VirAcanthamoeba_polyphaga_mimivirus
hypothetical_protein_MIMI_gp0179__YP_003986653__Acanthamoeba_polyphaga_mimivirus__212035
Identity
- Accession:
- YP_003986653 ↗
- Protein ID:
- hypothetical_protein_MIMI_gp0179
- Kingdom:
- euk
Quality
78.4
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Mimivirus›
Acanthamoeba_polyphaga_mimivirus
TaxID: 212035
Cluster
View cluster (6 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 10-134_357-424
D2
high
residues 136-201_257-346
Domain cluster:
rep: hypothetical_protein_H012_gp137__YP_007354749__Acanthamoeba_polyphaga_moumouvirus__1269028__D139-205_217-331
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19165.6 best | DUF5847 | 28.1 | 1.40e-06 | 62.8% | 23.6% |
CATH (68)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.82 | 68.0 | 6.44e-01 | 100.0% | 73.9% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.81 | 54.0 | 6.17e-01 | 98.7% | 89.7% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.81 | 62.0 | 6.78e-01 | 100.0% | 95.4% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.80 | 61.0 | 6.51e-01 | 100.0% | 91.0% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.79 | 59.0 | 6.27e-01 | 100.0% | 87.6% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.78 | 63.0 | 5.05e-01 | 84.0% | 76.7% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 62.0 | 5.13e-01 | 83.3% | 83.5% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 53.0 | 5.58e-01 | 75.6% | 77.5% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 61.0 | 5.16e-01 | 83.3% | 78.0% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.76 | 60.0 | 5.12e-01 | 82.1% | 86.9% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.76 | 61.0 | 4.97e-01 | 82.7% | 77.9% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.76 | 61.0 | 5.04e-01 | 84.0% | 83.8% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 59.0 | 6.41e-01 | 100.0% | 98.4% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.75 | 60.0 | 5.13e-01 | 84.0% | 76.0% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.75 | 70.0 | 6.57e-01 | 100.0% | 85.6% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.75 | 56.0 | 5.09e-01 | 78.2% | 81.4% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.75 | 50.0 | 5.45e-01 | 100.0% | 80.9% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 59.0 | 5.35e-01 | 84.0% | 86.1% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.72 | 56.0 | 5.96e-01 | 84.0% | 90.0% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.72 | 58.0 | 4.82e-01 | 84.0% | 86.3% |
| 4im0A04 | 1.20.1270.420 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 57.0 | 4.94e-01 | 84.0% | 80.7% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 56.0 | 5.18e-01 | 82.7% | 88.6% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.71 | 57.0 | 5.57e-01 | 100.0% | 77.7% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.71 | 55.0 | 5.02e-01 | 100.0% | 62.5% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.71 | 53.0 | 5.37e-01 | 100.0% | 79.1% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.71 | 66.0 | 5.15e-01 | 99.4% | 84.3% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.70 | 59.0 | 5.21e-01 | 89.1% | 85.2% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.70 | 56.0 | 4.80e-01 | 84.0% | 82.9% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.70 | 47.0 | 5.53e-01 | 100.0% | 98.1% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 53.0 | 4.93e-01 | 78.2% | 71.7% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.70 | 55.0 | 5.22e-01 | 82.7% | 95.1% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 57.0 | 4.73e-01 | 87.8% | 83.9% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 55.0 | 4.80e-01 | 84.6% | 87.9% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.68 | 62.0 | 5.94e-01 | 100.0% | 85.8% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.68 | 53.0 | 5.53e-01 | 92.3% | 86.9% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.68 | 51.0 | 5.42e-01 | 97.4% | 88.2% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 47.0 | 4.29e-01 | 100.0% | 53.7% |
| 3qa8A04 | 1.20.1270.250 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 54.0 | 4.68e-01 | 84.0% | 79.0% |
| 4akgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.67 | 53.0 | 5.18e-01 | 96.2% | 76.2% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 59.0 | 5.24e-01 | 91.0% | 87.6% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 52.0 | 4.69e-01 | 82.7% | 87.2% |
| 4jkvB02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 59.0 | 4.55e-01 | 96.2% | 49.0% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.66 | 52.0 | 4.85e-01 | 80.8% | 83.3% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 58.0 | 5.97e-01 | 94.2% | 100.0% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 61.0 | 6.05e-01 | 100.0% | 98.1% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 52.0 | 4.43e-01 | 84.0% | 81.5% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.65 | 46.0 | 4.72e-01 | 92.3% | 74.8% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 49.0 | 4.34e-01 | 78.2% | 73.9% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.65 | 51.0 | 4.76e-01 | 81.4% | 82.3% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.64 | 39.0 | 4.09e-01 | 96.8% | 66.2% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 58.0 | 4.78e-01 | 100.0% | 98.9% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.62 | 49.0 | 4.90e-01 | 81.4% | 87.9% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.61 | 41.0 | 4.80e-01 | 94.9% | 97.2% |
| 2hydA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.61 | 47.0 | 3.70e-01 | 80.8% | 42.1% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 42.0 | 4.72e-01 | 82.1% | 93.3% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 54.0 | 4.79e-01 | 100.0% | 93.4% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 45.0 | 4.19e-01 | 78.2% | 67.2% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 32.0 | 3.37e-01 | 94.2% | 57.4% |
| 5j1hA01 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 48.0 | 4.55e-01 | 87.2% | 79.7% |
| 7zo9A01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.57 | 43.0 | 3.47e-01 | 78.2% | 42.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 43.0 | 4.64e-01 | 80.1% | 91.7% |
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.57 | 40.0 | 4.49e-01 | 78.2% | 91.7% |
| 5haxA01 | 1.20.58.1780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 48.0 | 4.17e-01 | 91.7% | 70.8% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 50.0 | 4.50e-01 | 98.1% | 87.7% |
| 3r6nB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 48.0 | 4.23e-01 | 91.0% | 67.9% |
| 6g94A00 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.52 | 47.0 | 4.58e-01 | 98.1% | 95.3% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.52 | 47.0 | 4.21e-01 | 98.7% | 73.1% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.51 | 44.0 | 4.38e-01 | 96.8% | 98.2% |
ECOD (60)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3471820 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.85 | 80.0 | 6.87e-01 | 98.1% | 100.0% |
| 3398787 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.83 | 61.0 | 6.12e-01 | 84.0% | 74.4% |
| 3662019 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.81 | 58.0 | 6.02e-01 | 82.7% | 78.6% |
| 4944676 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.80 | 56.0 | 6.42e-01 | 87.2% | 96.5% |
| 3937801 | 4177.1.1.38 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin | 0.79 | 64.0 | 5.81e-01 | 83.3% | 78.5% |
| 3789396 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.79 | 63.0 | 4.95e-01 | 83.3% | 76.8% |
| 3505878 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.78 | 63.0 | 5.00e-01 | 84.0% | 78.0% |
| 3673192 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.78 | 67.0 | 6.52e-01 | 100.0% | 82.9% |
| 4121806 | 4177.1.1.66 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › ATG17_like | 0.78 | 62.0 | 4.76e-01 | 83.3% | 79.4% |
| 3670390 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.77 | 71.0 | 5.87e-01 | 98.7% | 93.3% |
| 3280676 | 150.8.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE | 0.77 | 62.0 | 5.96e-01 | 84.6% | 100.0% |
| 4000290 | 192.29.1.188 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › F_actin_bind | 0.77 | 58.0 | 6.35e-01 | 100.0% | 93.1% |
| 3298761 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.76 | 71.0 | 6.07e-01 | 100.0% | 95.8% |
| 3395314 | 601.15.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) | 0.76 | 69.0 | 6.96e-01 | 100.0% | 96.8% |
| 3532384 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.75 | 61.0 | 4.94e-01 | 84.0% | 76.1% |
| 3816459 | 3684.1.1.10 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 | 0.75 | 71.0 | 6.50e-01 | 100.0% | 94.4% |
| 3720250 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.75 | 49.0 | 5.16e-01 | 82.7% | 72.0% |
| 3587749 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 64.0 | 6.44e-01 | 98.1% | 90.3% |
| 3454282 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 70.0 | 6.76e-01 | 100.0% | 93.7% |
| 3411249 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.75 | 44.0 | 4.77e-01 | 78.2% | 69.2% |
| 3285409 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.75 | 59.0 | 5.58e-01 | 82.7% | 88.6% |
| 3651361 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.75 | 70.0 | 6.06e-01 | 100.0% | 88.7% |
| 3733141 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.73 | 59.0 | 6.13e-01 | 84.0% | 91.7% |
| 3458456 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.73 | 67.0 | 5.78e-01 | 98.7% | 97.0% |
| 3362557 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.73 | 57.0 | 5.15e-01 | 82.1% | 87.1% |
| 4956385 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.73 | 69.0 | 6.65e-01 | 100.0% | 93.7% |
| 3725261 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.73 | 59.0 | 4.75e-01 | 85.3% | 86.1% |
| 4010998 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.72 | 56.0 | 5.43e-01 | 80.1% | 89.7% |
| 3787599 | 3882.1.1.1 ↗ | alpha bundles › Atg17 › Atg17 › Atg17 › ATG17_like | 0.72 | 58.0 | 4.06e-01 | 83.3% | 59.8% |
| 3611133 | 1189.1.1.3 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP | 0.72 | 59.0 | 5.45e-01 | 85.3% | 94.4% |
| 3368549 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.72 | 52.0 | 4.65e-01 | 75.0% | 61.4% |
| 3603171 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.72 | 67.0 | 6.43e-01 | 100.0% | 90.3% |
| 3235225 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.72 | 56.0 | 5.00e-01 | 82.1% | 90.5% |
| 3685679 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 60.0 | 6.06e-01 | 89.7% | 96.1% |
| 3506533 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.70 | 66.0 | 6.31e-01 | 100.0% | 95.4% |
| 3698277 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.70 | 56.0 | 5.64e-01 | 84.0% | 86.9% |
| 3627942 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.70 | 49.0 | 4.71e-01 | 70.5% | 93.1% |
| 3340986 | 601.51.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin | 0.70 | 64.0 | 5.87e-01 | 100.0% | 86.5% |
| 3922271 | 4177.2.1.11 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ALIX_LYPXL_bnd | 0.70 | 56.0 | 5.21e-01 | 84.6% | 80.0% |
| 3758003 | 5054.1.1.9 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel | 0.70 | 59.0 | 4.61e-01 | 100.0% | 43.8% |
| 4665474 | 4177.2.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ATG17_like | 0.69 | 63.0 | 5.34e-01 | 100.0% | 87.5% |
| 3570028 | 904.1.1.0 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain | 0.68 | 56.0 | 5.41e-01 | 85.9% | 92.0% |
| 3659874 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.68 | 52.0 | 5.46e-01 | 82.1% | 86.2% |
| 3263327 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.68 | 60.0 | 6.19e-01 | 100.0% | 99.3% |
| 3697729 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.66 | 48.0 | 4.58e-01 | 88.5% | 63.8% |
| 3535192 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 53.0 | 5.01e-01 | 83.3% | 76.7% |
| 4946477 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.66 | 46.0 | 3.70e-01 | 71.2% | 40.7% |
| 3613946 | 1189.1.1.6 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ISG65-75 | 0.65 | 52.0 | 4.46e-01 | 84.6% | 76.8% |
| 5020818 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 50.0 | 3.38e-01 | 78.2% | 42.1% |
| 3215358 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.65 | 46.0 | 4.22e-01 | 73.7% | 56.0% |
| 3362816 | 4177.2.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain | 0.65 | 59.0 | 4.78e-01 | 100.0% | 83.4% |
| 5014971 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.63 | 45.0 | 4.05e-01 | 71.8% | 76.6% |
| 3626504 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 58.0 | 5.02e-01 | 100.0% | 75.2% |
| 3731804 | 5058.1.1.37 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PF25886 | 0.62 | 39.0 | 4.11e-01 | 73.7% | 68.3% |
| 3292475 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.61 | 56.0 | 4.61e-01 | 100.0% | 82.1% |
| 3276148 | 602.1.1.3 ↗ | alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like › Lyase_aromatic | 0.61 | 55.0 | 4.41e-01 | 99.4% | 78.3% |
| 3184310 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.60 | 56.0 | 4.70e-01 | 100.0% | 61.5% |
| 3227583 | 5050.1.1.48 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Frag1 | 0.59 | 48.0 | 4.37e-01 | 98.1% | 64.3% |
| 3788782 | 2004.1.1.199 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B | 0.55 | 44.0 | 3.13e-01 | 87.2% | 56.1% |
| 4024903 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.54 | 43.0 | 4.11e-01 | 96.8% | 71.1% |
D3
medium
residues 202-256