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hypothetical_protein_MIMI_gp0499

Euk-Vir

Acanthamoeba_polyphaga_mimivirus

hypothetical_protein_MIMI_gp0499__YP_003986972__Acanthamoeba_polyphaga_mimivirus__212035

Identity

Accession:
YP_003986972 ↗
Protein ID:
hypothetical_protein_MIMI_gp0499
Kingdom:
euk

Quality

79.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 42-91
PDB
Domain cluster: representative
CATH (69)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.90 83.0 5.28e-01 100.0% 25.8%
3pwfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.90 83.0 5.93e-01 100.0% 40.5%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.89 82.0 4.87e-01 100.0% 17.8%
3rklA00 6.10.140.1640 Special › Helix non-globular › Helix Hairpins › 0.89 80.0 6.74e-01 98.0% 63.7%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.88 81.0 5.10e-01 100.0% 67.4%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.88 80.0 6.10e-01 100.0% 50.0%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.88 81.0 6.19e-01 100.0% 58.5%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.88 78.0 6.57e-01 98.0% 64.2%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.88 81.0 6.06e-01 100.0% 46.4%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.88 79.0 6.59e-01 98.0% 64.2%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.87 79.0 7.24e-01 100.0% 78.1%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.86 79.0 6.86e-01 100.0% 84.9%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.86 77.0 5.96e-01 100.0% 47.6%
4a4kA01 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.86 78.0 5.80e-01 98.0% 46.0%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.85 75.0 5.73e-01 98.0% 43.8%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.85 74.0 4.97e-01 98.0% 89.6%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.85 78.0 7.20e-01 100.0% 79.4%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.85 75.0 6.98e-01 96.0% 78.7%
4a25B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.83 75.0 5.13e-01 100.0% 31.1%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.83 71.0 6.62e-01 98.0% 93.8%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.83 74.0 5.84e-01 100.0% 50.5%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 72.0 4.75e-01 98.0% 26.0%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.82 72.0 5.98e-01 100.0% 74.7%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.82 72.0 4.98e-01 100.0% 36.6%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.80 70.0 6.38e-01 98.0% 85.1%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 64.0 5.63e-01 88.0% 69.9%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.80 71.0 4.28e-01 100.0% 17.0%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.80 74.0 5.09e-01 100.0% 64.5%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.79 70.0 5.01e-01 100.0% 36.4%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 68.0 6.44e-01 100.0% 96.7%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.78 71.0 5.73e-01 100.0% 67.4%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.78 68.0 6.01e-01 100.0% 67.6%
2pusA04 6.10.140.300 Special › Helix non-globular › Helix Hairpins › 0.77 67.0 5.16e-01 98.0% 44.4%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.76 62.0 5.01e-01 92.0% 58.8%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 62.0 5.03e-01 100.0% 47.5%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 60.0 5.69e-01 100.0% 74.6%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 65.0 4.11e-01 100.0% 20.3%
3ph0C00 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.75 50.0 4.98e-01 98.0% 66.0%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.74 64.0 5.69e-01 100.0% 71.6%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 62.0 4.98e-01 98.0% 50.0%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.74 65.0 5.61e-01 98.0% 96.1%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.73 59.0 5.60e-01 96.0% 100.0%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.73 61.0 5.18e-01 98.0% 57.5%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 59.0 5.35e-01 98.0% 68.5%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.72 61.0 5.22e-01 100.0% 64.7%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.72 60.0 5.65e-01 100.0% 78.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.72 61.0 4.77e-01 100.0% 45.7%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.71 59.0 5.49e-01 100.0% 92.5%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 56.0 5.06e-01 96.0% 66.2%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 56.0 5.45e-01 98.0% 84.2%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 58.0 4.01e-01 100.0% 27.7%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 58.0 5.21e-01 96.0% 90.1%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 58.0 5.04e-01 100.0% 64.2%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.67 55.0 5.50e-01 100.0% 100.0%
1a22A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.67 56.0 3.91e-01 98.0% 97.2%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.67 58.0 4.14e-01 98.0% 45.8%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.67 54.0 4.89e-01 96.0% 67.6%
2aswA00 1.10.8.500 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › HAMP domain in histidine kinase 0.67 45.0 4.36e-01 76.0% 62.5%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 58.0 5.29e-01 100.0% 97.0%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 55.0 4.91e-01 100.0% 65.4%
3fedA03 1.20.930.40 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain 0.66 54.0 4.00e-01 100.0% 96.1%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 54.0 4.16e-01 96.0% 41.5%
1jalA03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.65 52.0 4.69e-01 100.0% 63.0%
2oauA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 55.0 4.44e-01 100.0% 60.8%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.64 52.0 4.51e-01 100.0% 57.0%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 50.0 4.53e-01 96.0% 66.7%
1vibA00 1.10.287.120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like 0.61 50.0 4.89e-01 96.0% 87.3%
2v40A02 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.55 41.0 3.55e-01 90.0% 46.6%
1o1yA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.52 40.0 2.66e-01 88.0% 46.1%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3204414 1.1.17.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.90 81.0 4.71e-01 98.0% 13.1%
3592036 3291.1.1.16 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Flagellar_rod 0.89 84.0 5.30e-01 100.0% 24.8%
4569106 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.89 82.0 4.65e-01 100.0% 21.3%
5018716 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.89 82.0 7.21e-01 100.0% 78.6%
4259085 3755.4.1.66 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal 0.89 82.0 4.94e-01 100.0% 95.5%
3600887 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.89 83.0 5.29e-01 100.0% 25.4%
4965940 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.88 81.0 5.64e-01 100.0% 35.9%
3798353 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.87 80.0 5.53e-01 100.0% 34.7%
4660205 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.87 78.0 5.57e-01 98.0% 62.2%
3598836 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.87 79.0 5.99e-01 100.0% 47.3%
3505296 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 78.0 4.97e-01 98.0% 22.8%
3482286 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.86 76.0 4.96e-01 98.0% 98.0%
3285463 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.86 80.0 6.40e-01 100.0% 57.8%
3811877 3937.1.1.0 alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 0.86 77.0 5.26e-01 100.0% 87.3%
149872 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.86 78.0 6.61e-01 100.0% 98.7%
1296342 101.1.2.456 alpha arrays › HTH › HTH › winged helix domain › HTH_MmpR5 0.86 78.0 5.46e-01 100.0% 34.0%
3466160 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.85 76.0 5.51e-01 98.0% 52.3%
3647336 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.85 77.0 5.62e-01 100.0% 47.2%
3994890 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.85 76.0 5.90e-01 100.0% 67.6%
3494616 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.84 76.0 6.23e-01 98.0% 78.8%
3607681 633.10.1.15 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 0.84 78.0 5.52e-01 100.0% 38.5%
3611298 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.84 75.0 5.43e-01 100.0% 78.2%
4987417 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.83 73.0 6.35e-01 98.0% 65.3%
3601441 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.83 75.0 5.90e-01 100.0% 50.0%
3611632 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.83 74.0 5.84e-01 100.0% 52.0%
3482539 192.8.1.288 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Ada3 0.82 74.0 5.82e-01 100.0% 52.0%
3707409 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.82 73.0 5.55e-01 100.0% 45.2%
3588068 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.82 74.0 6.03e-01 100.0% 57.8%
3818733 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.82 75.0 5.20e-01 98.0% 33.8%
4016292 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.82 75.0 5.36e-01 100.0% 40.7%
3947717 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 71.0 5.00e-01 100.0% 47.1%
3416299 611.9.1.10 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › NEDD4_Bsd2 0.81 73.0 5.52e-01 100.0% 43.5%
3965792 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.81 73.0 4.46e-01 100.0% 66.2%
1290191 159.1.3.1 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › putative NTP pyrophosphohydrolase Exig_1061 › PRA-PH 0.80 71.0 5.03e-01 100.0% 35.1%
4106620 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.80 72.0 6.23e-01 100.0% 69.3%
4680241 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.80 71.0 6.53e-01 100.0% 80.0%
3713350 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.79 69.0 5.21e-01 100.0% 45.8%
3336964 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.78 64.0 4.00e-01 100.0% 17.6%
4286197 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.78 69.0 5.91e-01 100.0% 65.0%
3287947 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.78 69.0 5.69e-01 100.0% 57.8%
4032912 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.78 69.0 6.04e-01 100.0% 66.7%
3181110 5086.1.1.110 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA 0.77 64.0 5.34e-01 98.0% 96.8%
3608194 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.77 66.0 4.40e-01 100.0% 80.3%
2732157 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.77 66.0 6.02e-01 100.0% 75.4%
3421989 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.77 66.0 4.95e-01 98.0% 39.2%
2893266 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.76 65.0 5.42e-01 100.0% 77.2%
4970333 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.75 66.0 5.33e-01 98.0% 56.8%
5024718 205.1.1.16 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_7 0.74 63.0 4.11e-01 94.0% 35.3%
3930310 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.72 57.0 4.92e-01 96.0% 70.8%
1879027 244.1.1.6 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase 0.70 57.0 3.46e-01 100.0% 17.3%
3693258 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.68 56.0 4.52e-01 100.0% 48.2%
4529282 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.68 55.0 4.73e-01 100.0% 54.4%
3542369 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.62 50.0 2.99e-01 100.0% 12.2%
D2 medium residues 92-180
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.70 33.0 3.44e-01 76.4% 47.1%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.66 42.0 4.50e-01 98.9% 74.0%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 50.0 4.94e-01 95.5% 78.7%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 50.0 4.72e-01 95.5% 69.8%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.63 43.0 4.42e-01 100.0% 72.4%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 49.0 4.53e-01 95.5% 67.9%
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 42.0 4.21e-01 100.0% 70.0%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 41.0 3.35e-01 100.0% 39.2%
2a3qA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.60 38.0 3.56e-01 100.0% 51.3%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.60 48.0 4.68e-01 87.6% 88.0%
2y2zA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 48.0 3.97e-01 98.9% 48.1%
1v4aA01 1.10.4050.10 Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE 0.60 36.0 3.42e-01 94.4% 49.5%
3u9jA00 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.59 49.0 4.12e-01 92.1% 78.3%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.59 43.0 3.51e-01 76.4% 83.9%
1qviA01 1.20.120.720 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Myosin VI head, motor domain, U50 subdomain 0.58 47.0 4.40e-01 91.0% 87.0%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 42.0 3.07e-01 77.5% 76.8%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.56 44.0 3.34e-01 100.0% 37.1%
3kdqA00 6.10.320.10 Special › Helix non-globular › Ferritin › 0.56 46.0 3.79e-01 100.0% 50.7%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.56 42.0 4.42e-01 95.5% 86.6%
7zd5C01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.56 40.0 2.76e-01 100.0% 21.1%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.56 42.0 3.30e-01 78.7% 49.2%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.54 43.0 3.67e-01 98.9% 51.0%
6nyyE01 1.20.58.760 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Peptidase M41 0.54 50.0 3.94e-01 100.0% 74.0%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.53 40.0 3.84e-01 100.0% 68.6%
5d91A02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.52 44.0 3.38e-01 91.0% 57.1%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.52 42.0 4.29e-01 100.0% 86.5%
1m4rB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 40.0 3.47e-01 86.5% 68.8%
ECOD (61)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3687615 109.24.1.0 alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 0.72 44.0 4.37e-01 100.0% 57.9%
4152656 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 48.0 2.73e-01 95.5% 7.4%
4988993 5086.1.1.231 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook 0.67 46.0 3.86e-01 95.5% 42.7%
4610474 547.1.1.0 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain 0.66 41.0 2.89e-01 91.0% 21.1%
4028685 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.66 50.0 4.67e-01 92.1% 64.5%
3712081 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.64 49.0 4.53e-01 92.1% 64.5%
4381440 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.64 51.0 4.62e-01 95.5% 64.3%
4574762 3782.1.1.4 a+b duplicates or obligate multimers › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related › DUF2127 0.64 45.0 3.85e-01 74.2% 81.3%
3642338 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.64 41.0 4.45e-01 92.1% 77.3%
4017372 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.64 49.0 4.44e-01 92.1% 61.7%
3485296 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.63 49.0 4.59e-01 92.1% 67.6%
3579472 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.63 48.0 4.20e-01 92.1% 54.6%
1000517 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.63 50.0 4.81e-01 95.5% 73.3%
4666900 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.63 50.0 4.42e-01 95.5% 59.2%
3935332 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.63 50.0 4.33e-01 95.5% 56.9%
4006691 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.63 43.0 3.87e-01 70.8% 69.2%
4681355 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.63 50.0 4.45e-01 95.5% 61.7%
3740332 1128.1.1.0 alpha bundles › LYR protein › LYR protein › LYR protein 0.63 44.0 4.65e-01 74.2% 98.8%
5019837 2003.1.1.24 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Shikimate_DH 0.62 40.0 2.90e-01 88.8% 22.7%
None 0.62 40.0 2.90e-01 88.8% 22.7%
60305 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.62 49.0 4.58e-01 95.5% 69.8%
4271212 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.61 49.0 4.33e-01 95.5% 60.2%
4964055 5069.1.1.6 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › COX15-CtaA 0.61 48.0 4.16e-01 84.3% 96.4%
5035493 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.61 49.0 4.58e-01 95.5% 70.5%
4984959 3758.1.1.113 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › Rad50_zn_hook 0.61 46.0 3.06e-01 95.5% 21.2%
3202986 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.61 48.0 4.26e-01 95.5% 59.2%
5078448 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.61 48.0 4.43e-01 95.5% 67.3%
3496927 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.61 53.0 3.85e-01 100.0% 95.1%
3937187 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.61 48.0 4.44e-01 95.5% 67.3%
3828336 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.61 48.0 4.38e-01 95.5% 64.9%
3270487 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.61 48.0 4.45e-01 95.5% 67.3%
3690513 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.60 48.0 4.14e-01 95.5% 55.6%
4399455 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.60 50.0 4.20e-01 91.0% 87.1%
3277797 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.60 41.0 4.35e-01 100.0% 78.8%
3265214 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.60 48.0 4.35e-01 95.5% 64.3%
3675304 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.60 47.0 4.25e-01 95.5% 61.7%
3594965 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.60 47.0 3.99e-01 95.5% 52.9%
4428260 109.54.1.12 alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › PF28770 0.59 46.0 3.88e-01 100.0% 50.3%
4541653 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.59 45.0 4.41e-01 92.1% 74.7%
3923871 192.2.1.48 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PF26022 0.59 41.0 3.32e-01 100.0% 38.2%
3756246 5086.1.1.117 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › WWC1 0.58 42.0 3.48e-01 76.4% 74.4%
3234976 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.58 45.0 4.23e-01 95.5% 67.3%
3757575 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.58 37.0 3.45e-01 100.0% 51.8%
3298752 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.58 38.0 3.48e-01 100.0% 51.3%
3237525 101.1.1.290 alpha arrays › HTH › HTH › Three-helical HTH › PBC 0.58 44.0 3.91e-01 95.5% 57.6%
3656598 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 41.0 3.65e-01 100.0% 52.3%
5064397 5086.1.1.231 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook 0.56 44.0 3.41e-01 100.0% 38.5%
4127216 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.56 39.0 3.57e-01 91.0% 55.7%
4524703 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.55 39.0 3.56e-01 92.1% 56.5%
3382610 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.54 43.0 3.12e-01 87.6% 77.4%
3608382 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.54 50.0 3.78e-01 98.9% 47.7%
3692753 5086.1.1.12 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Uds1 0.54 38.0 3.25e-01 100.0% 44.0%
4181293 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.53 44.0 4.12e-01 95.5% 72.7%
3602143 3755.3.1.305 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook 0.53 44.0 3.16e-01 95.5% 32.9%
3924998 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.52 43.0 2.86e-01 100.0% 22.3%
5014330 148.1.3.402 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Rad50_zn_hook 0.52 43.0 4.04e-01 95.5% 71.8%
4629785 3922.1.1.269 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Rad50_zn_hook 0.52 43.0 2.99e-01 95.5% 27.2%
3597412 5076.1.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier 0.52 45.0 3.30e-01 100.0% 76.2%
3420307 192.8.1.248 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › KIF21A_4th 0.52 48.0 3.27e-01 100.0% 46.7%
3508862 159.1.1.1 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.51 38.0 3.61e-01 93.3% 66.7%
4025452 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.50 42.0 3.88e-01 95.5% 71.3%