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hypothetical_protein_MIV120R

Euk-Vir

Invertebrate_iridescent_virus_3

hypothetical_protein_MIV120R__YP_654692__Invertebrate_iridescent_virus_3__345201

Identity

Accession:
YP_654692 ↗
Protein ID:
hypothetical_protein_MIV120R
Kingdom:
euk

Quality

79.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 223-452
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 115.4 4.00e-33 75.2% 73.1%
D2 medium residues 1-51_158-220
PDB
Domain cluster: representative
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4b08A01 2.40.50.730 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.85 59.0 6.98e-01 90.4% 100.0%
3u4vA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.77 60.0 5.99e-01 93.0% 79.3%
3iayA01 2.40.50.730 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.74 61.0 6.58e-01 94.7% 100.0%
2cqaA01 2.40.50.360 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RuvBL1 DNA/RNA binding domain 0.74 47.0 5.73e-01 90.4% 100.0%
3u4zA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.73 55.0 5.61e-01 94.7% 80.7%
1jb7A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.73 57.0 5.72e-01 95.6% 81.0%
1fguB01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.72 57.0 5.96e-01 89.5% 91.4%
4egvA02 2.40.50.840 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.71 43.0 5.17e-01 83.3% 92.0%
3f2bA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.71 52.0 5.62e-01 91.2% 90.6%
3q8dA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.71 46.0 5.43e-01 88.6% 97.4%
3tssA02 2.40.50.110 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.69 43.0 5.33e-01 85.1% 100.0%
3k7uC00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 56.0 5.96e-01 93.9% 99.0%
4gs3A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.68 52.0 5.73e-01 93.0% 100.0%
4me3A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.67 49.0 5.24e-01 91.2% 88.7%
6aqgA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 51.0 4.72e-01 94.7% 64.5%
1ue6D00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 53.0 5.60e-01 93.9% 94.2%
1x6oA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 44.0 5.22e-01 90.4% 100.0%
1fguB02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.65 57.0 5.56e-01 97.4% 87.1%
1xjvA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.64 56.0 5.16e-01 93.0% 95.1%
1gd7A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.62 52.0 5.36e-01 96.5% 95.4%
2vnuD02 2.40.50.700 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.62 41.0 4.72e-01 90.4% 98.7%
1se8A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.62 53.0 5.41e-01 97.4% 94.6%
1kopA00 3.10.200.10 Alpha Beta › Roll › Carbonic Anhydrase II › Alpha carbonic anhydrase 0.62 47.0 3.79e-01 80.7% 68.2%
1pxfA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.62 50.0 5.07e-01 94.7% 89.2%
3kf6A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 53.0 5.01e-01 93.0% 83.8%
4twlA00 3.10.200.10 Alpha Beta › Roll › Carbonic Anhydrase II › Alpha carbonic anhydrase 0.61 48.0 3.78e-01 84.2% 81.6%
3q31A00 3.10.200.10 Alpha Beta › Roll › Carbonic Anhydrase II › Alpha carbonic anhydrase 0.60 46.0 3.65e-01 80.7% 67.8%
2vqeL00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.59 47.0 4.56e-01 84.2% 76.6%
3nppA00 2.40.50.480 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Protein of unknown function DUF1093 0.59 42.0 4.66e-01 99.1% 98.9%
1lm0A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.59 49.0 5.18e-01 91.2% 100.0%
4xfwA00 3.10.200.10 Alpha Beta › Roll › Carbonic Anhydrase II › Alpha carbonic anhydrase 0.57 47.0 3.82e-01 90.4% 83.2%
2l73A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.52 37.0 3.50e-01 74.6% 90.2%
6upsA01 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.52 37.0 3.37e-01 74.6% 61.3%
1gd5A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.51 36.0 3.46e-01 72.8% 96.2%
ECOD (94)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5025207 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.88 64.0 7.37e-01 88.6% 100.0%
5027238 2.1.1.25 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 0.86 66.0 5.96e-01 90.4% 60.7%
4024809 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.84 64.0 7.19e-01 89.5% 100.0%
5055355 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.83 64.0 7.14e-01 93.0% 100.0%
5012082 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.83 66.0 7.21e-01 93.0% 98.9%
3492154 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.81 70.0 6.89e-01 89.5% 100.0%
5005284 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.81 65.0 7.10e-01 89.5% 100.0%
4001702 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.80 71.0 7.10e-01 93.0% 92.2%
3964458 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.80 54.0 6.03e-01 89.5% 87.8%
3738561 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 64.0 6.69e-01 83.3% 100.0%
3417038 2.1.1.179 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › REV3_N 0.79 71.0 6.88e-01 93.9% 92.8%
3222288 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 69.0 6.96e-01 91.2% 90.4%
3496491 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 64.0 6.66e-01 83.3% 99.0%
3791987 2.1.1.25 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 0.79 70.0 6.98e-01 92.1% 92.2%
3891602 2.1.1.276 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1, REV3_N 0.79 71.0 6.75e-01 93.9% 94.6%
4134937 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 68.0 7.12e-01 93.0% 98.1%
4018347 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 59.0 6.46e-01 94.7% 92.6%
3788812 304.114.1.6 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › DNA_pol_B_exo1 0.79 69.0 5.25e-01 92.1% 78.3%
4449302 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.78 56.0 5.82e-01 92.1% 80.0%
3579168 2.1.1.179 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › REV3_N 0.78 67.0 5.96e-01 90.4% 93.5%
3991931 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.77 64.0 6.34e-01 94.7% 83.3%
437095 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.77 60.0 5.99e-01 93.0% 79.3%
3314558 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.77 64.0 5.87e-01 95.6% 69.4%
3630622 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.77 65.0 6.40e-01 95.6% 85.0%
3317763 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.77 58.0 6.43e-01 88.6% 100.0%
3374948 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.76 61.0 6.54e-01 91.2% 96.0%
4997715 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 68.0 5.79e-01 93.0% 100.0%
3826195 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.76 54.0 5.80e-01 93.0% 84.0%
3480547 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.76 68.0 6.74e-01 93.9% 93.2%
3296674 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.76 63.0 6.48e-01 95.6% 91.8%
4972474 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 68.0 4.06e-01 93.9% 25.6%
4025113 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.76 64.0 6.16e-01 87.7% 87.2%
3220752 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.75 60.0 6.17e-01 93.0% 88.2%
3811669 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.74 61.0 6.26e-01 95.6% 90.9%
4026723 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.74 61.0 6.25e-01 94.7% 90.9%
3214780 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.74 59.0 6.18e-01 94.7% 92.4%
3822890 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.74 64.0 5.97e-01 95.6% 75.7%
3441179 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.74 64.0 6.19e-01 95.6% 84.0%
4976869 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.73 65.0 6.50e-01 93.0% 98.3%
4221404 2.1.1.57 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N 0.73 48.0 5.62e-01 91.2% 95.0%
3827585 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.73 59.0 6.19e-01 90.4% 92.4%
3356276 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.73 64.0 6.21e-01 95.6% 84.8%
3808110 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.73 65.0 5.87e-01 95.6% 72.0%
3446499 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.73 63.0 6.26e-01 95.6% 88.3%
3213233 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.73 60.0 6.03e-01 95.6% 87.0%
3642370 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.73 63.0 6.26e-01 96.5% 88.3%
4220176 2.1.1.289 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon, Rep-A_N 0.73 62.0 4.66e-01 95.6% 39.2%
3625857 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.73 63.0 6.04e-01 96.5% 81.5%
3236144 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.72 58.0 5.92e-01 94.7% 87.3%
3681185 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.72 63.0 4.87e-01 96.5% 44.2%
5076488 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.72 55.0 5.89e-01 89.5% 91.0%
3661180 2.1.1.223 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.72 60.0 6.37e-01 94.7% 100.0%
3680383 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.72 61.0 6.07e-01 95.6% 87.5%
3677576 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.71 62.0 5.93e-01 95.6% 81.5%
3336960 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 57.0 5.95e-01 92.1% 91.4%
3666656 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 61.0 5.87e-01 95.6% 80.8%
5081844 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 56.0 5.49e-01 91.2% 77.5%
3173704 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.71 56.0 5.61e-01 94.7% 81.7%
3931674 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 61.0 6.09e-01 94.7% 90.4%
3738963 2.1.1.157 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › CDC24_OB2 0.71 51.0 5.49e-01 90.4% 88.4%
3263785 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 62.0 5.47e-01 93.0% 90.6%
3654541 2.1.1.223 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.71 57.0 5.81e-01 97.4% 88.2%
3445197 2.1.1.130 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.71 61.0 6.03e-01 96.5% 88.3%
4245059 2.1.1.57 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N 0.70 48.0 5.49e-01 93.0% 94.1%
3247575 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.70 54.0 5.36e-01 91.2% 76.7%
3652178 2.1.1.223 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.70 58.0 5.17e-01 96.5% 63.1%
3412139 2.1.1.176 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › OB_MEIOB_N 0.70 62.0 5.72e-01 95.6% 85.5%
3853782 2.1.1.269 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF30822 0.70 55.0 5.45e-01 93.9% 79.2%
3750530 2.1.1.269 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF30822 0.69 55.0 5.19e-01 93.9% 70.4%
4061669 2.1.1.57 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N 0.69 47.0 5.42e-01 93.0% 97.5%
3807621 2.1.1.348 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223, Rep-A_N 0.69 64.0 4.76e-01 100.0% 85.5%
3358498 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.69 51.0 5.41e-01 95.6% 87.0%
3657721 2.1.1.223 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.69 59.0 5.33e-01 97.4% 68.7%
3675935 2.1.1.223 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.69 58.0 5.50e-01 95.6% 76.3%
5023075 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.68 55.0 5.17e-01 85.1% 93.3%
3444970 2.1.1.223 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.66 58.0 5.58e-01 96.5% 82.3%
5043745 2.1.1.287 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Zn_ribbon_TiaS 0.66 54.0 4.54e-01 85.1% 94.4%
3654791 2.1.1.76 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › REPA_OB_2 0.66 59.0 5.43e-01 96.5% 79.3%
3254800 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 59.0 5.28e-01 96.5% 86.5%
3658019 2.1.1.285 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › CDC24_OB3, CDC24_OB2 0.66 59.0 4.26e-01 96.5% 45.0%
3657702 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 58.0 5.43e-01 95.6% 79.3%
5039189 2.1.1.287 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Zn_ribbon_TiaS 0.64 56.0 4.96e-01 91.2% 99.4%
3330560 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.64 58.0 5.16e-01 97.4% 71.2%
3359808 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.64 58.0 5.54e-01 97.4% 87.7%
3279044 2.1.1.314 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF27099 0.64 37.0 4.64e-01 74.6% 100.0%
3239000 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.63 56.0 5.33e-01 94.7% 86.9%
5076884 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.62 57.0 5.22e-01 98.2% 83.4%
3963716 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.62 49.0 5.05e-01 91.2% 88.2%
3783321 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.62 50.0 4.68e-01 96.5% 70.0%
4341423 2.1.1.279 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF4131 0.61 52.0 5.19e-01 95.6% 87.5%
5058885 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.61 55.0 4.89e-01 98.2% 69.4%
3544108 2.1.1.133 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF4503 0.58 45.0 4.64e-01 80.7% 92.4%
3273439 246.3.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.52 41.0 2.99e-01 83.3% 91.7%
3862290 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.51 36.0 3.29e-01 72.8% 82.6%
D4 medium residues 498-530_705-820
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 61.2 1.20e-16 79.9% 26.3%
D5 medium residues 531-565_621-704
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 70.4 1.90e-19 100.0% 24.3%
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.88 52.0 5.40e-01 84.0% 63.2%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.87 51.0 6.57e-01 83.2% 97.3%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.86 52.0 4.00e-01 84.9% 30.9%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.82 43.0 5.96e-01 84.9% 98.4%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.81 48.0 4.32e-01 87.4% 45.5%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 48.0 5.86e-01 85.7% 87.7%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.81 48.0 4.43e-01 89.1% 48.3%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.79 52.0 6.22e-01 79.0% 97.6%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.79 48.0 6.07e-01 83.2% 100.0%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.78 48.0 4.61e-01 84.9% 54.8%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.78 45.0 5.85e-01 84.0% 98.6%
2qe7G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.77 48.0 5.33e-01 85.7% 77.3%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 44.0 4.79e-01 89.1% 66.7%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.76 46.0 4.95e-01 88.2% 69.6%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 44.0 5.60e-01 90.8% 100.0%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 48.0 5.87e-01 86.6% 100.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 47.0 5.13e-01 84.9% 74.7%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 43.0 4.70e-01 82.4% 67.3%
2wyhB04 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.75 47.0 5.06e-01 96.6% 74.3%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.74 46.0 4.83e-01 88.2% 68.9%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.74 48.0 5.36e-01 84.0% 83.0%
1rfyB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.73 44.0 5.10e-01 84.0% 81.8%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.72 58.0 6.12e-01 94.1% 91.7%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.71 54.0 5.74e-01 92.4% 89.6%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.70 32.0 4.01e-01 85.7% 68.9%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.69 54.0 5.78e-01 90.8% 93.2%
6ygiB01 1.10.4090.10 Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus 0.68 54.0 5.01e-01 98.3% 67.1%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.68 41.0 4.18e-01 88.2% 60.3%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 51.0 5.45e-01 89.9% 91.2%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.67 43.0 4.96e-01 85.7% 90.6%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.66 40.0 4.84e-01 84.9% 94.7%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 46.0 4.99e-01 85.7% 87.0%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.63 40.0 3.86e-01 79.0% 55.6%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.63 38.0 4.73e-01 84.0% 98.6%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.62 39.0 4.56e-01 84.0% 91.5%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.62 56.0 3.97e-01 96.6% 80.7%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 50.0 4.72e-01 84.0% 79.9%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 38.0 4.67e-01 79.8% 100.0%
3itfA00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.59 40.0 4.14e-01 95.8% 73.9%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 52.0 4.43e-01 95.8% 81.4%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 51.0 4.97e-01 95.8% 86.5%
2fsfB04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.57 43.0 3.57e-01 79.8% 80.7%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 42.0 3.12e-01 88.2% 30.5%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 37.0 4.35e-01 71.4% 100.0%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 44.0 3.62e-01 88.2% 87.6%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 45.0 3.97e-01 95.0% 81.3%
7e4mA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 47.0 3.57e-01 99.2% 73.7%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 43.0 3.80e-01 89.9% 68.3%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3187995 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.92 50.0 5.26e-01 84.0% 60.0%
4405928 5086.1.1.196 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YknX 0.91 51.0 6.78e-01 84.9% 97.1%
3935462 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.86 52.0 4.55e-01 84.9% 42.9%
3194783 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.85 47.0 4.87e-01 90.8% 57.4%
5057329 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 50.0 4.60e-01 84.9% 49.0%
3608554 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.83 52.0 4.78e-01 84.0% 51.7%
3607135 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 52.0 4.92e-01 86.6% 55.6%
4017817 3922.1.1.229 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Cep57_MT_bd 0.82 52.0 4.91e-01 84.9% 55.0%
3598199 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.82 51.0 4.29e-01 85.7% 40.5%
3254975 603.2.1.2 alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.80 49.0 5.02e-01 84.9% 63.5%
3239865 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.80 48.0 4.64e-01 88.2% 53.3%
3923952 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.79 48.0 4.69e-01 89.9% 56.2%
3757869 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.79 53.0 5.95e-01 95.8% 86.3%
4473674 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.79 54.0 5.68e-01 88.2% 76.4%
3180530 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.79 51.0 5.38e-01 93.3% 71.8%
3349325 5086.1.1.135 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF7615 0.79 50.0 6.07e-01 87.4% 96.2%
3497911 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.79 54.0 5.20e-01 95.8% 62.2%
3928597 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.78 48.0 4.55e-01 84.0% 52.9%
4497169 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 47.0 4.58e-01 84.0% 55.4%
4967728 5058.1.1.100 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PsiE 0.78 51.0 4.74e-01 88.2% 54.5%
4324499 3755.1.1.3 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › SPAM 0.77 51.0 4.70e-01 81.5% 54.5%
3953227 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.77 48.0 5.24e-01 85.7% 75.0%
154974 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.76 47.0 5.68e-01 84.0% 94.8%
4276314 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 49.0 3.94e-01 80.7% 35.5%
3717206 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.76 53.0 5.39e-01 88.2% 73.0%
4025 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.76 47.0 5.13e-01 84.9% 74.7%
3959609 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.75 47.0 5.14e-01 85.7% 76.5%
3802240 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.75 50.0 5.42e-01 94.1% 81.0%
3732045 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.74 51.0 3.84e-01 84.9% 32.5%
3631657 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 44.0 3.16e-01 84.0% 21.5%
4942736 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 45.0 4.82e-01 88.2% 70.5%
3696833 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 43.0 4.60e-01 86.6% 66.7%
3286816 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.73 46.0 4.63e-01 82.4% 63.3%
3283686 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.72 41.0 5.14e-01 81.5% 94.3%
4984327 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.72 55.0 5.87e-01 87.4% 88.6%
3368750 192.8.1.263 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF7615 0.72 52.0 5.58e-01 84.0% 84.8%
3295251 605.1.1.185 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF7615 0.72 52.0 5.48e-01 84.0% 80.9%
3231045 101.1.1.117 alpha arrays › HTH › HTH › Three-helical HTH › CHDCT2 0.72 44.0 4.69e-01 89.1% 69.5%
3898383 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 45.0 4.43e-01 85.7% 60.0%
3962893 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.71 47.0 5.18e-01 81.5% 84.2%
4935068 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.70 43.0 5.14e-01 85.7% 96.0%
4336724 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.69 53.0 5.59e-01 87.4% 86.4%
3725506 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 54.0 5.66e-01 91.6% 90.0%
3946910 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.68 50.0 4.22e-01 75.6% 61.1%
3170876 192.7.1.30 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › CUX1_N 0.68 49.0 4.99e-01 85.7% 76.5%
4586684 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 47.0 4.54e-01 80.7% 63.8%
4671 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.68 51.0 5.37e-01 88.2% 84.5%
3812957 606.1.1.13 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › DUF3475 0.67 58.0 4.62e-01 93.3% 80.9%
4039014 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.67 53.0 5.49e-01 89.9% 88.2%
3286299 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.67 53.0 5.52e-01 89.9% 89.1%
4966215 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.64 49.0 4.36e-01 79.0% 92.1%
3875361 633.23.1.1 alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin 0.64 52.0 4.59e-01 95.8% 61.2%
3306743 192.29.1.101 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N 0.63 51.0 4.94e-01 96.6% 76.3%
3914072 633.23.1.19 alpha bundles › Bromodomain-like › Claudin › Claudin › TMEM37 0.63 57.0 4.87e-01 95.8% 67.2%
3339348 606.1.1.12 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Rx_N 0.63 52.0 5.02e-01 95.0% 80.0%
3470163 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.62 55.0 4.31e-01 95.8% 72.6%
3635930 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.62 55.0 4.99e-01 93.3% 73.5%
3598481 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 49.0 4.78e-01 84.9% 76.2%
4270097 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.61 49.0 5.19e-01 95.0% 97.1%
5012794 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.60 54.0 3.80e-01 95.8% 70.1%
3275930 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.60 54.0 4.15e-01 95.8% 68.8%
3600606 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.60 53.0 4.68e-01 96.6% 92.0%
3782312 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.60 50.0 3.68e-01 89.1% 65.4%
3234009 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.59 49.0 3.61e-01 88.2% 54.3%
2600 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.58 46.0 4.23e-01 82.4% 77.5%
5005480 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 45.0 3.95e-01 85.7% 55.4%
D6 medium residues 566-620
PDB
Domain cluster: representative
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2a26B01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.90 64.0 7.14e-01 81.8% 93.2%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.88 66.0 7.07e-01 81.8% 89.6%
7k3zG01 3.50.7.10 Alpha Beta › 3-Layer(bba) Sandwich › GroEL › GroEL 0.87 60.0 3.92e-01 78.2% 18.8%
2oxlA00 1.20.5.5260 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.87 61.0 5.82e-01 72.7% 64.5%
6epyA01 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.83 66.0 4.16e-01 85.5% 85.5%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.81 64.0 5.64e-01 83.6% 76.3%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.80 74.0 4.81e-01 100.0% 64.1%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.80 69.0 4.90e-01 90.9% 43.8%
7vevA01 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.80 64.0 4.08e-01 85.5% 90.7%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.80 64.0 4.93e-01 85.5% 66.7%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.80 63.0 4.62e-01 85.5% 34.3%
6z01B03 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.80 63.0 4.44e-01 87.3% 29.9%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.79 63.0 5.12e-01 87.3% 48.4%
6humG01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.79 62.0 4.36e-01 85.5% 28.7%
8anqA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.79 63.0 4.08e-01 85.5% 33.9%
1vf6C00 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.78 56.0 5.84e-01 76.4% 82.4%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 65.0 5.88e-01 89.1% 67.1%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 61.0 5.42e-01 87.3% 61.3%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.77 61.0 6.35e-01 85.5% 90.2%
3dkqA02 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.77 59.0 6.26e-01 81.8% 100.0%
1ezjA01 1.10.287.320 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Viral phosphoprotein oligmorisation site domain 0.77 52.0 5.04e-01 70.9% 62.9%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.77 65.0 4.61e-01 90.9% 40.0%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 58.0 5.09e-01 80.0% 59.0%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.76 69.0 4.70e-01 100.0% 70.6%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.76 63.0 5.18e-01 92.7% 51.6%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 69.0 4.57e-01 96.4% 40.5%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 60.0 5.50e-01 87.3% 97.2%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 58.0 5.18e-01 87.3% 59.7%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.75 58.0 4.90e-01 83.6% 96.7%
1go3F02 6.10.140.10 Special › Helix non-globular › Helix Hairpins › 0.75 48.0 5.12e-01 74.5% 76.6%
4r42A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 68.0 4.60e-01 100.0% 34.8%
4ze8A03 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.74 58.0 3.88e-01 85.5% 90.0%
2h1jA00 1.10.1370.30 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.73 58.0 3.30e-01 87.3% 13.3%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.73 59.0 4.94e-01 89.1% 78.9%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.73 57.0 4.56e-01 85.5% 43.5%
1dd9A03 1.20.50.20 Mainly Alpha › Up-down Bundle › Pheromone ER-1 › DnaG, RNA polymerase domain, helical bundle 0.72 49.0 4.84e-01 76.4% 66.1%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 67.0 5.52e-01 100.0% 62.4%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.72 65.0 5.35e-01 96.4% 61.5%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.72 62.0 4.72e-01 94.5% 48.4%
4hkaA02 1.10.287.3810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 52.0 5.36e-01 81.8% 84.3%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.71 51.0 3.43e-01 78.2% 33.0%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 65.0 4.27e-01 100.0% 28.7%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 65.0 5.26e-01 100.0% 63.9%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 61.0 4.46e-01 100.0% 36.8%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.70 57.0 5.01e-01 92.7% 94.1%
2c0gA02 1.20.1150.12 Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain 0.70 60.0 4.87e-01 96.4% 84.9%
2qw6D00 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.68 46.0 4.08e-01 80.0% 46.5%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.68 61.0 4.48e-01 100.0% 42.6%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 51.0 4.62e-01 83.6% 69.7%
1d2mA03 6.10.140.240 Special › Helix non-globular › Helix Hairpins › 0.66 47.0 4.47e-01 76.4% 75.8%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.63 54.0 4.19e-01 98.2% 73.0%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 50.0 3.66e-01 89.1% 32.3%
2wzkA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.62 50.0 3.89e-01 90.9% 70.9%
3dv9A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 44.0 4.13e-01 78.2% 100.0%
4jvyB00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.59 45.0 3.20e-01 87.3% 92.1%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 45.0 3.32e-01 83.6% 49.7%
1n1cA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.57 45.0 4.08e-01 94.5% 73.2%
2ffjA02 1.10.285.20 Mainly Alpha › Orthogonal Bundle › Glutamate Dehydrogenase; Chain A, domain 3 › Uncharacterised protein PF01937, DUF89, domain 2 0.54 36.0 3.51e-01 78.2% 60.0%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3258150 192.17.1.0 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.93 63.0 7.32e-01 80.0% 97.5%
4366957 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.92 66.0 7.28e-01 81.8% 91.1%
4261003 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.88 66.0 7.31e-01 87.3% 95.6%
5016885 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.88 67.0 6.29e-01 83.6% 67.7%
5050929 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.87 67.0 5.89e-01 83.6% 58.7%
3396140 192.14.1.1 alpha bundles › Long alpha-hairpin › Siah interacting protein N terminal domain-like › Siah interacting protein N terminal domain-like › Siah-Interact_N 0.87 65.0 6.54e-01 83.6% 78.2%
3989252 6132.1.1.1 alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix_N 0.86 63.0 5.97e-01 81.8% 66.2%
3976663 3812.1.1.1 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E 0.85 63.0 5.97e-01 81.8% 66.2%
3879987 601.48.1.0 alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain 0.84 65.0 6.15e-01 85.5% 69.2%
4987994 633.2.1.0 alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein 0.84 58.0 5.27e-01 76.4% 55.7%
3909630 601.48.1.0 alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain 0.84 67.0 5.91e-01 85.5% 61.3%
3988221 2004.1.1.554 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrB_inter 0.82 63.0 3.72e-01 80.0% 31.5%
3488829 2005.1.1.12 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1e 0.82 61.0 3.63e-01 81.8% 11.8%
4023439 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 65.0 5.93e-01 87.3% 65.7%
3227178 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.82 58.0 3.98e-01 74.5% 25.7%
3518809 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.82 60.0 3.78e-01 81.8% 15.9%
3742626 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 63.0 3.48e-01 81.8% 8.0%
4930292 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.81 65.0 5.93e-01 85.5% 67.1%
3302917 2004.1.1.505 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, AAA_30 0.80 67.0 4.04e-01 89.1% 14.8%
3586032 605.1.1.237 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Patched 0.80 62.0 4.91e-01 81.8% 44.8%
3414767 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.80 59.0 5.16e-01 81.8% 53.8%
3685099 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.80 65.0 6.09e-01 85.5% 75.4%
3918963 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.79 61.0 3.70e-01 87.3% 14.5%
3594704 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 69.0 4.01e-01 92.7% 18.0%
4532371 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.79 62.0 6.46e-01 87.3% 92.0%
3927321 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 67.0 5.79e-01 89.1% 61.3%
3638713 2003.1.2.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.78 64.0 3.64e-01 87.3% 9.8%
3940953 109.4.1.623 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1 0.78 66.0 3.62e-01 90.9% 15.0%
3718917 6132.1.1.0 alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain 0.77 61.0 5.45e-01 85.5% 65.3%
4040184 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.77 61.0 6.36e-01 87.3% 94.0%
3503749 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.76 60.0 4.89e-01 85.5% 98.0%
4279139 3819.2.1.1 alpha complex topology › CRISPR-associated endonuclease Cas9 alpha-helical lobe › F. novicida CRISPR-associated endonuclease Cas9 alpha-helical lobe › F. novicida CRISPR-associated endonuclease Cas9 alpha-helical lobe › Csx12 0.75 59.0 3.27e-01 87.3% 14.8%
4954852 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.75 62.0 4.24e-01 89.1% 28.3%
3369775 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.75 68.0 4.19e-01 98.2% 74.0%
4024442 2488.1.1.7 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › EMG1 0.73 68.0 4.33e-01 100.0% 39.9%
3247204 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.73 66.0 6.40e-01 96.4% 93.3%
2142296 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.73 66.0 5.29e-01 96.4% 54.1%
3418094 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.73 67.0 5.81e-01 100.0% 71.2%
3497934 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.72 67.0 4.24e-01 100.0% 70.4%
3290879 3922.1.1.155 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF4349 0.72 67.0 6.12e-01 100.0% 84.3%
4848262 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.72 57.0 4.58e-01 87.3% 82.2%
3498716 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.72 67.0 5.19e-01 100.0% 55.5%
3568235 192.15.1.165 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › zf-B_box 0.72 66.0 4.36e-01 100.0% 26.8%
3713604 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 67.0 4.02e-01 100.0% 18.5%
3884815 904.1.1.1 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain › zf-B_box 0.71 66.0 4.33e-01 100.0% 28.1%
3392973 109.4.1.32 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G 0.71 57.0 3.41e-01 85.5% 23.9%
3221190 904.1.1.0 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain 0.71 55.0 3.72e-01 89.1% 22.9%
5048590 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.71 65.0 5.10e-01 100.0% 67.3%
3385229 2003.1.9.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.71 60.0 3.58e-01 98.2% 14.0%
3570403 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.71 66.0 4.89e-01 100.0% 49.6%
3922888 109.4.1.889 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_M 0.70 65.0 4.29e-01 100.0% 29.3%
3718848 1132.1.1.0 extended segments › Mitochondrial complex I, B16.6 subunit › Mitochondrial complex I, B16.6 subunit › Mitochondrial complex I, B16.6 subunit 0.70 64.0 5.05e-01 100.0% 51.4%
3224742 3755.3.1.9 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › SH3BP5 0.69 61.0 4.08e-01 100.0% 27.4%
3527193 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.69 59.0 3.73e-01 98.2% 18.3%
3635782 3291.1.1.53 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › CENPU 0.68 62.0 4.18e-01 100.0% 32.1%
3857330 904.1.1.0 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain 0.67 59.0 4.21e-01 100.0% 33.8%
3219646 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.67 58.0 5.84e-01 96.4% 96.4%
3920380 904.1.1.1 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain › zf-B_box 0.67 58.0 3.99e-01 100.0% 29.2%
3550485 904.1.1.22 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain › zf-B_box, TRIM_CC 0.66 57.0 3.88e-01 100.0% 26.3%
3902068 109.4.1.1369 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MA3, MIF4G 0.65 58.0 3.33e-01 100.0% 11.0%
4001468 904.1.1.1 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain › zf-B_box 0.63 51.0 3.49e-01 98.2% 24.8%
3805872 4095.1.1.1 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N 0.58 46.0 3.62e-01 90.9% 91.2%
D7 medium residues 821-880_935-1042
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 40.0 3.10e-10 81.5% 32.5%
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3iayA07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.86 73.0 7.69e-01 89.9% 96.7%
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.85 73.0 7.50e-01 88.7% 97.5%
4qclA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.83 73.0 7.33e-01 91.1% 97.6%
4jndA01 1.10.1740.220 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.60 23.0 2.61e-01 75.6% 42.3%
2w53B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 39.0 3.89e-01 97.0% 65.9%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.57 20.0 3.04e-01 91.1% 74.6%
3keyA01 1.10.10.1080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain 0.54 29.0 3.70e-01 92.3% 95.4%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 32.0 3.68e-01 89.9% 82.8%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.53 31.0 3.29e-01 81.5% 63.0%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 28.0 3.04e-01 86.3% 56.9%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 29.0 3.43e-01 97.0% 79.5%
2lfhA00 4.10.280.10 Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain 0.51 17.0 2.65e-01 94.6% 73.5%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4030147 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.87 76.0 7.13e-01 89.9% 92.8%
4547010 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.86 74.0 7.27e-01 89.3% 87.8%
3597971 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.86 74.0 7.22e-01 89.3% 87.8%
3178384 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 74.0 7.13e-01 89.9% 92.4%
3993980 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 74.0 6.88e-01 89.9% 91.0%
3584203 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 75.0 7.37e-01 91.1% 94.9%
3705557 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 74.0 7.59e-01 91.7% 98.1%
3214821 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 70.0 7.41e-01 89.9% 97.3%
4025114 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.82 75.0 7.48e-01 94.0% 100.0%
3480544 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.82 75.0 7.57e-01 94.6% 98.2%
3404727 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.82 74.0 7.02e-01 94.0% 81.4%
5035013 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 68.0 7.05e-01 88.1% 96.9%
4977733 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.80 67.0 7.11e-01 86.3% 100.0%
5073477 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.80 68.0 7.17e-01 87.5% 100.0%
4929241 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.80 66.0 6.86e-01 89.9% 92.3%
5073668 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 63.0 6.80e-01 82.1% 100.0%
5058883 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.79 68.0 7.09e-01 89.3% 100.0%
5044378 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 64.0 6.79e-01 83.9% 97.3%
5009174 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 69.0 7.15e-01 93.5% 96.2%
4978606 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.78 67.0 7.01e-01 89.3% 99.4%
4931233 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.78 62.0 6.71e-01 82.7% 96.6%
5048997 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 70.0 6.92e-01 94.6% 92.0%
5041309 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.77 68.0 6.86e-01 93.5% 94.6%
4959102 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.76 67.0 6.72e-01 92.9% 93.5%
3665128 109.4.1.893 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UTP6_C 0.60 36.0 3.69e-01 92.9% 59.4%
4053061 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.57 17.0 3.20e-01 70.2% 89.8%
3173183 101.1.2.134 alpha arrays › HTH › HTH › winged helix domain › Stn1_C 0.55 29.0 3.75e-01 91.7% 93.3%
3218491 5054.1.1.70 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Yip1 0.55 31.0 3.17e-01 81.5% 54.1%
3564283 109.4.1.570 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps8 0.53 33.0 2.14e-01 92.9% 13.4%
4975796 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.50 24.0 3.11e-01 82.7% 78.9%
D8 medium residues 881-934
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ysiA01 2.20.70.10 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › 0.68 39.0 4.74e-01 85.2% 93.9%
2kxqA01 2.20.70.10 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › 0.60 34.0 3.90e-01 75.9% 93.3%
4bg7A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.56 40.0 3.46e-01 81.5% 57.1%
3ey7A01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.55 41.0 3.24e-01 81.5% 78.5%
3le4A00 2.20.70.10 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › 0.54 39.0 3.93e-01 77.8% 83.6%
2v90C00 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.53 41.0 3.57e-01 90.7% 74.2%
1a2fA02 1.10.420.10 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 2 › Peroxidase, domain 2 0.52 44.0 3.46e-01 96.3% 49.6%
1i3zA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.52 41.0 3.57e-01 100.0% 68.9%
2iq1A00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.52 42.0 2.82e-01 100.0% 86.4%
1l5xA00 3.40.1210.10 Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase 0.52 37.0 2.42e-01 79.6% 91.3%
2mdiA00 2.20.70.10 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › 0.52 35.0 3.55e-01 72.2% 94.6%
1pcfA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.51 36.0 3.46e-01 77.8% 84.8%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3924730 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.66 38.0 4.40e-01 83.3% 85.7%
4889754 386.1.1.1 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2 0.62 40.0 3.90e-01 92.6% 58.3%
3404953 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.62 41.0 4.55e-01 88.9% 92.5%
3999380 2002.1.1.20 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PI-PLC-Y,PI-PLC-X 0.60 40.0 2.68e-01 70.4% 25.5%
3924553 101.1.1.76 alpha arrays › HTH › HTH › Three-helical HTH › Integrase_H2C2 0.60 46.0 3.92e-01 87.0% 60.0%
3877952 389.1.1.0 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin 0.57 31.0 3.47e-01 83.3% 70.0%
3285378 220.1.1.221 beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF3093 0.56 45.0 3.66e-01 88.9% 75.2%
2048178 244.2.1.10 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › NDH2_C 0.56 31.0 2.93e-01 72.2% 43.9%
3706889 109.4.1.20 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RYDR_ITPR 0.54 39.0 2.50e-01 81.5% 15.6%
3441362 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.54 33.0 2.39e-01 70.4% 20.0%
3738632 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.53 38.0 2.40e-01 83.3% 32.6%
3494576 2499.1.1.1 a/b three-layered sandwiches › Subtilisin-like › Subtilisin-like › Subtilisin-like › Peptidase_S8 0.53 42.0 2.82e-01 92.6% 40.4%
3311607 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.53 42.0 3.44e-01 92.6% 60.0%
5025956 221.4.1.1 a+b two layers › beta-Grasp › Nudix › Nudix › NUDIX 0.53 40.0 2.96e-01 83.3% 30.7%
3410562 708.1.1.4 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › FLYWCH 0.52 41.0 3.86e-01 90.7% 91.4%
5980 227.1.1.9 a+b two layers › DNA clamp › DNA clamp › DNA clamp › DNA_PPF 0.52 35.0 2.92e-01 79.6% 35.5%
3452325 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.52 39.0 2.70e-01 83.3% 92.6%
3583479 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.52 34.0 3.69e-01 85.2% 92.5%
3937179 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.51 41.0 3.31e-01 100.0% 84.8%
3718923 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.50 37.0 2.32e-01 79.6% 93.2%
4112122 386.1.1.81 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › DUF1391 0.50 33.0 3.79e-01 77.8% 95.0%
D9 medium residues 1085-1141
PDB