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hypothetical_protein_SPPV_143
Euk-VirSheeppox_virus
hypothetical_protein_SPPV_143__NP_659720__Sheeppox_virus__10266
Identity
- Accession:
- NP_659720 ↗
- Protein ID:
- hypothetical_protein_SPPV_143
- Kingdom:
- euk
Quality
85.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Capripoxvirus›
Sheeppox_virus
TaxID: 10266
Cluster
View cluster (36 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 22-96
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06227.18 best | Poxv_Bcl-2-like | 65.3 | 8.00e-18 | 100.0% | 45.5% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3acxA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.60 | 49.0 | 3.38e-01 | 92.0% | 94.0% |
D2
medium
residues 97-161
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06227.18 best | Poxv_Bcl-2-like | 42.1 | 1.10e-10 | 84.6% | 33.3% |
CATH (46)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 56.0 | 4.91e-01 | 78.5% | 80.2% |
| 1rqgA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.74 | 60.0 | 4.58e-01 | 89.2% | 73.5% |
| 2x7iA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.74 | 53.0 | 4.21e-01 | 75.4% | 56.2% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.73 | 52.0 | 5.14e-01 | 73.8% | 88.2% |
| 6ldkA01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.73 | 60.0 | 4.38e-01 | 89.2% | 59.3% |
| 3eo8A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.73 | 49.0 | 3.39e-01 | 70.8% | 23.7% |
| 2a26B01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.72 | 47.0 | 5.56e-01 | 73.8% | 100.0% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 59.0 | 4.48e-01 | 90.8% | 80.5% |
| 1yzmA00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.72 | 49.0 | 5.59e-01 | 73.8% | 100.0% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.72 | 59.0 | 4.76e-01 | 89.2% | 72.7% |
| 2k36A00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.70 | 61.0 | 4.70e-01 | 100.0% | 43.0% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.69 | 49.0 | 5.42e-01 | 75.4% | 96.1% |
| 2yxyA01 | 1.10.287.880 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Hypothetical protein YfhH domain | 0.69 | 50.0 | 5.58e-01 | 78.5% | 100.0% |
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.69 | 47.0 | 5.33e-01 | 73.8% | 95.8% |
| 4malA00 | 1.20.58.2200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 43.0 | 4.54e-01 | 81.5% | 71.2% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 51.0 | 4.73e-01 | 81.5% | 97.6% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.68 | 49.0 | 4.47e-01 | 76.9% | 89.7% |
| 2l35A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.67 | 47.0 | 4.82e-01 | 73.8% | 87.3% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 50.0 | 4.88e-01 | 80.0% | 84.9% |
| 1p49A02 | 1.10.287.550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 49.0 | 5.15e-01 | 78.5% | 94.9% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 46.0 | 4.83e-01 | 75.4% | 81.0% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.67 | 47.0 | 5.22e-01 | 73.8% | 100.0% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.66 | 45.0 | 4.69e-01 | 70.8% | 83.1% |
| 3vurA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 53.0 | 4.47e-01 | 90.8% | 88.5% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.65 | 48.0 | 4.70e-01 | 80.0% | 77.5% |
| 4lqqB00 | 1.20.140.30 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › MOB kinase activator | 0.65 | 50.0 | 3.88e-01 | 83.1% | 38.4% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 48.0 | 4.90e-01 | 80.0% | 79.7% |
| 2qvaA02 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.65 | 48.0 | 5.23e-01 | 81.5% | 96.2% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.65 | 50.0 | 4.83e-01 | 84.6% | 89.3% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.65 | 51.0 | 3.66e-01 | 89.2% | 48.8% |
| 3p42A02 | 6.10.250.2280 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.63 | 44.0 | 4.36e-01 | 72.3% | 100.0% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.63 | 42.0 | 4.49e-01 | 76.9% | 82.1% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 46.0 | 3.14e-01 | 83.1% | 47.7% |
| 1zhcA00 | 6.10.280.50 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 42.0 | 4.07e-01 | 72.3% | 67.1% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 53.0 | 4.46e-01 | 100.0% | 84.7% |
| 2g38B00 | 1.20.1260.20 | Mainly Alpha › Up-down Bundle › Ferritin › PPE superfamily | 0.62 | 45.0 | 3.32e-01 | 78.5% | 52.6% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 49.0 | 4.19e-01 | 89.2% | 93.8% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 46.0 | 4.53e-01 | 84.6% | 90.3% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.61 | 45.0 | 4.39e-01 | 80.0% | 73.2% |
| 2q83A02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.61 | 49.0 | 3.39e-01 | 89.2% | 72.1% |
| 1go3F02 | 6.10.140.10 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 36.0 | 4.15e-01 | 87.7% | 83.0% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 45.0 | 4.53e-01 | 84.6% | 81.5% |
| 1cpyA02 | 1.10.287.410 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 40.0 | 3.97e-01 | 72.3% | 68.1% |
| 1f5qB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.58 | 41.0 | 3.29e-01 | 75.4% | 71.7% |
| 6z01B03 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.57 | 44.0 | 3.46e-01 | 87.7% | 78.6% |
| 2vwaA00 | 1.20.58.1330 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein | 0.54 | 42.0 | 3.72e-01 | 86.2% | 78.8% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4099273 | 140.1.1.6 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1,tRNA-synt_1g | 0.74 | 61.0 | 4.11e-01 | 89.2% | 48.5% |
| 4883518 | 304.1.1.0 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain | 0.72 | 47.0 | 4.72e-01 | 70.8% | 64.7% |
| 3296414 | 192.29.1.168 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF641 | 0.71 | 50.0 | 4.90e-01 | 73.8% | 91.4% |
| 3343635 | 5043.2.1.1 ↗ | extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain › Mlo | 0.71 | 48.0 | 4.88e-01 | 70.8% | 75.4% |
| 3318774 | 3812.1.1.7 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › Mlo | 0.71 | 48.0 | 4.85e-01 | 70.8% | 75.4% |
| 5031927 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.71 | 48.0 | 4.40e-01 | 70.8% | 56.5% |
| 3819834 | 605.6.1.8 ↗ | alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like › Mlo | 0.70 | 48.0 | 4.57e-01 | 70.8% | 65.3% |
| 3802185 | 192.8.1.359 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF641 | 0.70 | 52.0 | 5.07e-01 | 78.5% | 75.7% |
| 5046679 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.70 | 49.0 | 4.82e-01 | 75.4% | 68.6% |
| 3448294 | 3826.1.1.33 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › eIF-4B | 0.69 | 52.0 | 4.72e-01 | 80.0% | 61.2% |
| 4269685 | 192.11.1.1 ↗ | alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB › UVR | 0.68 | 51.0 | 5.25e-01 | 84.6% | 84.1% |
| 59125 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.68 | 55.0 | 4.47e-01 | 90.8% | 80.3% |
| 4944874 | 605.1.1.353 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HATPase_c | 0.68 | 49.0 | 4.84e-01 | 76.9% | 74.3% |
| 3625181 | 3710.1.1.3 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Ribophorin_II_C | 0.67 | 49.0 | 4.25e-01 | 80.0% | 49.5% |
| 3191420 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 50.0 | 5.04e-01 | 80.0% | 80.0% |
| 3379561 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.66 | 54.0 | 3.63e-01 | 90.8% | 73.7% |
| 3527990 | 192.17.1.6 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › CC2D1A-B_DM14 | 0.66 | 49.0 | 4.78e-01 | 78.5% | 72.9% |
| 223256 | 109.1.1.7 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_3 | 0.65 | 52.0 | 4.29e-01 | 90.8% | 78.1% |
| 3943184 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.65 | 48.0 | 4.77e-01 | 80.0% | 75.7% |
| 3715687 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.65 | 47.0 | 3.06e-01 | 75.4% | 20.0% |
| 3237324 | 3710.1.1.1 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 | 0.65 | 50.0 | 5.21e-01 | 84.6% | 90.0% |
| 3784740 | 3712.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 | 0.64 | 48.0 | 4.60e-01 | 80.0% | 72.0% |
| 3993228 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.64 | 46.0 | 3.09e-01 | 76.9% | 45.3% |
| 3890294 | 4970.1.1.22 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › Focal_AT | 0.63 | 52.0 | 5.22e-01 | 90.8% | 100.0% |
| 2774421 | 616.1.1.1 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15 | 0.63 | 51.0 | 3.76e-01 | 90.8% | 36.9% |
| 4419515 | 150.1.1.59 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F | 0.61 | 48.0 | 4.59e-01 | 90.8% | 81.2% |
| 4861524 | 540.1.1.1 ↗ | few secondary structure elements › Cytochrome c oxidase subunit h › Cytochrome c oxidase subunit h › Cytochrome c oxidase subunit h › COX6B | 0.60 | 51.0 | 4.86e-01 | 98.5% | 87.3% |
| 5052725 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.60 | 45.0 | 4.44e-01 | 83.1% | 78.6% |
| 1506772 | 3812.1.1.1 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E | 0.59 | 42.0 | 4.18e-01 | 78.5% | 75.7% |
| None | — | 0.57 | 46.0 | 3.03e-01 | 96.9% | 27.4% |