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hypothetical_protein_VACWR201
Euk-VirVaccinia_virus
hypothetical_protein_VACWR201__YP_233083__Vaccinia_virus__10245
Identity
- Accession:
- YP_233083 ↗
- Protein ID:
- hypothetical_protein_VACWR201
- Kingdom:
- euk
Quality
70.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Orthopoxvirus_vaccinia
TaxID: 10245
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-55
Domain cluster:
representative
CATH (51)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5j1hA01 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.92 | 72.0 | 4.80e-01 | 100.0% | 24.7% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.86 | 66.0 | 5.93e-01 | 83.3% | 100.0% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.82 | 72.0 | 6.67e-01 | 98.1% | 91.2% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.82 | 72.0 | 4.90e-01 | 100.0% | 58.0% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.81 | 59.0 | 5.73e-01 | 77.8% | 98.4% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.81 | 71.0 | 6.32e-01 | 100.0% | 68.8% |
| 2g2dA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.81 | 70.0 | 4.95e-01 | 100.0% | 32.5% |
| 4u1cA01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.80 | 60.0 | 6.12e-01 | 79.6% | 90.4% |
| 2ynqB00 | 1.25.40.680 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain | 0.80 | 66.0 | 4.76e-01 | 94.4% | 33.1% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.79 | 65.0 | 6.16e-01 | 92.6% | 76.9% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.79 | 69.0 | 6.25e-01 | 100.0% | 87.8% |
| 3r6nA02 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 67.0 | 4.82e-01 | 96.3% | 34.2% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.78 | 66.0 | 5.96e-01 | 100.0% | 69.3% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.77 | 67.0 | 5.38e-01 | 98.1% | 56.2% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.77 | 60.0 | 5.57e-01 | 96.3% | 66.2% |
| 2rklF00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.77 | 60.0 | 6.09e-01 | 85.2% | 88.5% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.77 | 68.0 | 5.50e-01 | 100.0% | 58.8% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.77 | 63.0 | 6.19e-01 | 100.0% | 86.4% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.76 | 65.0 | 6.01e-01 | 100.0% | 79.2% |
| 6t0bc01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 67.0 | 5.90e-01 | 100.0% | 74.4% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.75 | 64.0 | 5.82e-01 | 100.0% | 76.6% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 66.0 | 6.03e-01 | 100.0% | 85.9% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.74 | 62.0 | 5.72e-01 | 100.0% | 82.4% |
| 1wpbG01 | 1.10.287.680 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 51.0 | 5.10e-01 | 81.5% | 72.2% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 65.0 | 4.84e-01 | 100.0% | 42.4% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.74 | 65.0 | 4.56e-01 | 100.0% | 41.7% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.74 | 65.0 | 5.73e-01 | 100.0% | 93.8% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.73 | 58.0 | 6.04e-01 | 92.6% | 100.0% |
| 1vmgA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.73 | 58.0 | 5.10e-01 | 94.4% | 58.5% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 65.0 | 5.68e-01 | 100.0% | 72.8% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.73 | 62.0 | 4.71e-01 | 100.0% | 70.3% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 62.0 | 6.01e-01 | 100.0% | 87.1% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.73 | 62.0 | 5.92e-01 | 100.0% | 90.6% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.72 | 61.0 | 4.92e-01 | 100.0% | 51.8% |
| 2icwG01 | 1.20.120.390 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hla class ii histocompatibility antigen, dr alpha chain. Chain D, domain 1 | 0.72 | 61.0 | 4.75e-01 | 100.0% | 89.5% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.71 | 58.0 | 3.86e-01 | 90.7% | 24.9% |
| 4i9oA00 | 1.10.246.20 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain | 0.70 | 50.0 | 4.44e-01 | 75.9% | 53.8% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 60.0 | 5.03e-01 | 100.0% | 67.0% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.70 | 54.0 | 4.39e-01 | 85.2% | 43.0% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 58.0 | 5.26e-01 | 92.6% | 71.2% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.70 | 56.0 | 4.84e-01 | 98.1% | 56.2% |
| 2gsqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.69 | 58.0 | 4.74e-01 | 100.0% | 50.0% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 58.0 | 5.19e-01 | 100.0% | 67.9% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 57.0 | 5.64e-01 | 98.1% | 93.1% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.67 | 54.0 | 4.38e-01 | 100.0% | 47.6% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 58.0 | 5.51e-01 | 100.0% | 85.9% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.67 | 51.0 | 5.12e-01 | 94.4% | 87.3% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 55.0 | 5.22e-01 | 94.4% | 78.5% |
| 1jalA03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.65 | 51.0 | 4.54e-01 | 88.9% | 66.7% |
| 2iexA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.63 | 42.0 | 4.31e-01 | 96.3% | 72.5% |
| 2aj4B03 | 1.20.1440.340 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 54.0 | 3.84e-01 | 100.0% | 43.8% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1164229 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.85 | 77.0 | 7.19e-01 | 100.0% | 81.8% |
| 5058780 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.84 | 71.0 | 5.71e-01 | 94.4% | 51.4% |
| 4406905 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.78 | 67.0 | 6.24e-01 | 100.0% | 82.9% |
| 3597506 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.78 | 67.0 | 6.10e-01 | 100.0% | 81.3% |
| 4937556 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.78 | 66.0 | 6.38e-01 | 96.3% | 85.0% |
| 3595968 | 605.2.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 | 0.77 | 68.0 | 6.01e-01 | 100.0% | 82.5% |
| 4961508 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.76 | 64.0 | 5.87e-01 | 100.0% | 73.3% |
| 4963338 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.75 | 60.0 | 5.85e-01 | 96.3% | 81.7% |
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.75 | 64.0 | 5.61e-01 | 100.0% | 69.4% |
| 3372432 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.75 | 63.0 | 5.69e-01 | 100.0% | 73.8% |
| 3877354 | 3291.1.1.14 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › LAP2alpha | 0.75 | 66.0 | 4.49e-01 | 100.0% | 53.8% |
| 4395525 | 192.4.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 | 0.75 | 62.0 | 5.88e-01 | 100.0% | 78.5% |
| 5066104 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.73 | 65.0 | 3.72e-01 | 100.0% | 38.7% |
| 4024396 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 64.0 | 4.82e-01 | 100.0% | 48.9% |
| 3493358 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.73 | 62.0 | 5.36e-01 | 100.0% | 61.1% |
| 4005270 | 3718.1.1.15 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › COX4_pro | 0.73 | 61.0 | 5.22e-01 | 100.0% | 60.0% |
| 3794775 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.73 | 63.0 | 5.93e-01 | 98.1% | 84.6% |
| 3570117 | 375.6.1.2 ↗ | few secondary structure elements › Rubredoxin-like › FlhC-like › FlhC-like › PF31275 | 0.72 | 59.0 | 5.81e-01 | 98.1% | 88.3% |
| 5011468 | 101.1.2.31 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha | 0.72 | 59.0 | 4.55e-01 | 92.6% | 40.8% |
| 3071342 | 605.1.1.2 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim | 0.72 | 61.0 | 5.65e-01 | 96.3% | 78.3% |
| 4619538 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.72 | 61.0 | 4.83e-01 | 98.1% | 47.8% |
| 4964259 | 5055.1.1.0 ↗ | extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel | 0.72 | 60.0 | 6.06e-01 | 96.3% | 98.2% |
| 58582 | 605.2.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › SSV1_D-63 | 0.71 | 60.0 | 5.98e-01 | 94.4% | 96.4% |
| 3180119 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.71 | 63.0 | 5.45e-01 | 100.0% | 65.9% |
| 4595635 | 148.1.3.26 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 | 0.71 | 63.0 | 4.48e-01 | 100.0% | 33.8% |
| 4943086 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.71 | 58.0 | 5.42e-01 | 98.1% | 74.3% |
| 5056100 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.71 | 59.0 | 5.43e-01 | 100.0% | 74.7% |
| 4206858 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.71 | 60.0 | 4.83e-01 | 100.0% | 47.8% |
| 3930829 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.70 | 58.0 | 5.38e-01 | 100.0% | 74.7% |
| 3732397 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.70 | 61.0 | 4.77e-01 | 100.0% | 78.3% |
| 3608485 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.70 | 59.0 | 4.76e-01 | 100.0% | 47.8% |
| 4013967 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.69 | 61.0 | 3.58e-01 | 100.0% | 12.9% |
| 144301 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.69 | 55.0 | 5.11e-01 | 100.0% | 69.9% |
| 4447644 | 2004.1.1.514 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_29, SbcC_Walker_B | 0.63 | 56.0 | 3.35e-01 | 100.0% | 16.5% |