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hypothetical_protein_VARVgp048
Euk-VirVariola_virus
hypothetical_protein_VARVgp048__NP_042092__Variola_virus__10255
Identity
- Accession:
- NP_042092 ↗
- Protein ID:
- hypothetical_protein_VARVgp048
- Kingdom:
- euk
Quality
77.9
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Variola_virus
TaxID: 10255
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-58
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17467.8 best | E7R | 144.7 | 1.00e-42 | 100.0% | 91.7% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 66.0 | 5.84e-01 | 96.4% | 90.9% |
| 2a3qA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.75 | 56.0 | 4.42e-01 | 80.0% | 44.2% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 57.0 | 5.66e-01 | 81.8% | 81.0% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.75 | 56.0 | 5.19e-01 | 81.8% | 83.1% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.75 | 65.0 | 5.57e-01 | 100.0% | 86.8% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.74 | 54.0 | 5.77e-01 | 78.2% | 89.6% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 55.0 | 5.04e-01 | 80.0% | 62.0% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 55.0 | 5.34e-01 | 81.8% | 83.9% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 55.0 | 4.15e-01 | 81.8% | 35.4% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 53.0 | 4.35e-01 | 80.0% | 43.1% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.72 | 51.0 | 5.31e-01 | 80.0% | 82.0% |
| 4fppB01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.70 | 53.0 | 4.84e-01 | 80.0% | 67.6% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 52.0 | 4.35e-01 | 80.0% | 58.5% |
| 2aplA02 | 1.10.8.340 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like | 0.68 | 49.0 | 4.25e-01 | 76.4% | 50.6% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.67 | 51.0 | 4.39e-01 | 80.0% | 54.9% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 48.0 | 3.08e-01 | 80.0% | 16.9% |
| 3eslA01 | 1.20.58.2070 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 55.0 | 4.97e-01 | 94.5% | 89.3% |
| 2bskB00 | 1.10.287.810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains | 0.64 | 45.0 | 4.24e-01 | 72.7% | 66.2% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.64 | 45.0 | 4.92e-01 | 78.2% | 91.1% |
| 1vt0k00 | 1.10.3230.20 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › P22 tail accessory factor (Gp4) | 0.64 | 56.0 | 4.16e-01 | 100.0% | 71.0% |
| 2jx4A01 | 6.10.140.460 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 45.0 | 4.72e-01 | 80.0% | 97.9% |
| 3wd6A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 50.0 | 4.10e-01 | 98.2% | 66.9% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 50.0 | 4.22e-01 | 96.4% | 65.3% |
| 3p3lA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.60 | 48.0 | 2.91e-01 | 90.9% | 41.9% |
| 1jb0K00 | 1.20.860.20 | Mainly Alpha › Up-down Bundle › Alpha-t-alpha › Photosystem I PsaK, reaction centre | 0.60 | 40.0 | 4.30e-01 | 70.9% | 82.6% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.59 | 44.0 | 3.64e-01 | 80.0% | 56.7% |
| 2uubR00 | 4.10.640.10 | Few Secondary Structures › Irregular › 30s Ribosomal Protein S18 › Ribosomal protein S18 | 0.54 | 45.0 | 4.16e-01 | 96.4% | 78.1% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3693025 | 3710.1.1.1 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 | 0.78 | 60.0 | 5.82e-01 | 81.8% | 86.7% |
| 3595069 | 604.1.1.199 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26165 | 0.76 | 65.0 | 6.03e-01 | 96.4% | 95.7% |
| 3976635 | 602.3.1.1 ↗ | alpha arrays › L-aspartase middle domain-like › TssK neck domain › TssK neck domain › T6SS_VasE | 0.75 | 57.0 | 4.37e-01 | 81.8% | 41.6% |
| 3231978 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.75 | 54.0 | 3.85e-01 | 78.2% | 34.5% |
| 3989824 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.70 | 51.0 | 5.29e-01 | 80.0% | 88.0% |
| 3587564 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.70 | 52.0 | 4.56e-01 | 78.2% | 54.4% |
| 3258925 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.70 | 52.0 | 4.85e-01 | 80.0% | 62.9% |
| 3448294 | 3826.1.1.33 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › eIF-4B | 0.69 | 51.0 | 4.37e-01 | 78.2% | 51.8% |
| 3281203 | 604.17.1.0 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like | 0.68 | 48.0 | 5.00e-01 | 80.0% | 86.0% |
| 5079006 | 101.1.2.27 ↗ | alpha arrays › HTH › HTH › winged helix domain › LexA_DNA_bind | 0.67 | 50.0 | 3.73e-01 | 80.0% | 31.4% |
| 3286277 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.67 | 57.0 | 3.99e-01 | 96.4% | 80.0% |
| 4507133 | 3710.1.1.1 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 | 0.65 | 47.0 | 4.04e-01 | 80.0% | 46.3% |
| 3281670 | 101.1.2.49 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C | 0.65 | 55.0 | 3.93e-01 | 96.4% | 82.9% |
| 4300890 | 3710.1.1.1 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 | 0.65 | 47.0 | 4.55e-01 | 80.0% | 69.2% |
| 4634678 | 507.1.1.0 ↗ | alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related | 0.65 | 49.0 | 3.54e-01 | 80.0% | 28.4% |
| 3585864 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.65 | 47.0 | 3.29e-01 | 80.0% | 23.7% |
| 3992589 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 56.0 | 3.68e-01 | 100.0% | 30.4% |
| 3992452 | 150.5.1.74 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › CUX1_N | 0.63 | 46.0 | 4.09e-01 | 78.2% | 58.7% |
| 4612826 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.62 | 44.0 | 4.01e-01 | 80.0% | 53.8% |
| 4373664 | 574.1.1.0 ↗ | alpha bundles › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp module (SWAP domain) | 0.57 | 50.0 | 4.13e-01 | 100.0% | 64.0% |