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hypothetical_protein_VARVgp091

Euk-Vir

Variola_virus

hypothetical_protein_VARVgp091__NP_042135__Variola_virus__10255

Identity

Accession:
NP_042135 ↗
Protein ID:
hypothetical_protein_VARVgp091
Kingdom:
euk

Quality

74.0 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Variola_virus

TaxID: 10255

Cluster

View cluster (35 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 238-393
PDB
Domain cluster: rep: Salt_Pond_R1_B_H2O_MG_scaffold_1_prodigal-single.1__X__X__00295__D161-347
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF21004.4 best MCEL_GT_NTPase 130.2 3.80e-38 64.7% 88.5%
D2 high residues 399-504
PDB
D3 medium residues 28-60_97-132_148-161_191-224
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF10640.15 best MCEL_TPase 45.1 1.20e-11 46.2% 31.3%
PF10640.15 MCEL_TPase 32.3 1.00e-07 29.9% 16.2%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ckbD02 3.20.100.20 Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › 0.94 84.0 6.72e-01 92.3% 91.7%
3b82A06 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 36.0 3.60e-01 77.8% 62.0%
3e3xA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 36.0 4.07e-01 77.8% 85.1%
4dezA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.54 34.0 3.61e-01 100.0% 71.7%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 36.0 3.86e-01 93.2% 81.2%
1x7vA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 36.0 3.92e-01 100.0% 83.7%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 38.0 4.11e-01 100.0% 89.8%
1v8cA02 3.30.1370.80 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain 0.53 35.0 4.11e-01 89.7% 98.8%
1q8bA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 34.0 3.77e-01 91.5% 81.7%
4dpoB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 39.0 4.14e-01 99.1% 91.1%
2apoA03 3.30.70.3190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 35.0 3.86e-01 100.0% 88.0%
2ftrA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 38.0 4.00e-01 100.0% 88.3%
1lq9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 39.0 3.99e-01 97.4% 83.0%
3e8oB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 35.0 3.72e-01 100.0% 82.0%
5ixuA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 36.0 3.78e-01 94.0% 82.4%
1y7pB01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.51 34.0 4.07e-01 78.6% 100.0%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1147806 868.1.1.7 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › MCEL_TPase 0.94 86.0 6.75e-01 94.9% 87.6%
5053029 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.53 39.0 4.21e-01 100.0% 94.7%
4051078 304.4.1.71 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › DUF4937 0.52 36.0 3.68e-01 97.4% 72.2%
4385049 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.52 39.0 4.05e-01 94.0% 86.7%
4983809 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.52 33.0 3.83e-01 93.2% 92.5%
4943559 304.16.1.0 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like 0.51 35.0 3.83e-01 100.0% 91.0%
3604620 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.51 37.0 4.04e-01 100.0% 91.9%
3274800 304.4.1.14 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Dabb 0.51 37.0 3.94e-01 100.0% 86.7%
3163591 304.13.1.1 ↗ a+b two layers › Alpha-beta plaits › Hypothetical protein VC0424 › Hypothetical protein VC0424 › RraB 0.51 35.0 3.53e-01 100.0% 69.1%
4542034 304.45.1.1 ↗ a+b two layers › Alpha-beta plaits › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › HPPK 0.50 35.0 3.38e-01 100.0% 60.7%
3697122 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.50 36.0 3.74e-01 95.7% 80.0%
3834353 1075.4.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.50 37.0 3.87e-01 98.3% 86.7%
3615945 304.18.1.1 ↗ a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS › FDX-ACB 0.50 38.0 4.13e-01 100.0% 98.9%
D4 medium residues 61-96_133-147_162-190
PDB
Domain cluster: rep: mRNA_capping_enzyme_large_subunit__YP_010085378__Eastern_grey_kangaroopox_virus__2042482__D72-123_138-160_176-203
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF10640.15 best MCEL_TPase 50.3 2.90e-13 57.5% 29.8%
PF10640.15 MCEL_TPase 48.1 1.40e-12 46.2% 19.2%
D5 medium residues 565-712_767-787
PDB
Domain cluster: rep: IMGVR_UViG_3300009616_000257-3300009616-Ga0116111_100275611__D486-632
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03291.23 best mRNA_G-N7_MeTrfase 54.8 1.10e-14 95.9% 48.9%
D6 medium residues 713-766
PDB
Domain cluster: rep: mRNA_capping_enzyme_large_subunit__YP_784299__Nile_crocodilepox_virus__1285600__D719-769
D7 medium residues 788-844
PDB