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hypothetical_protein_VARVgp156

Euk-Vir

Variola_virus

hypothetical_protein_VARVgp156__NP_042200__Variola_virus__10255

Identity

Accession:
NP_042200 ↗
Protein ID:
hypothetical_protein_VARVgp156
Kingdom:
euk

Quality

90.3 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Variola_virus

TaxID: 10255

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-57
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01073.26 best 3Beta_HSD 49.3 5.10e-13 96.4% 19.6%
CATH (81)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3aw9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.90 74.0 4.88e-01 100.0% 24.7%
6kv9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.88 72.0 4.77e-01 100.0% 24.6%
4j1qA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.88 81.0 4.69e-01 100.0% 14.9%
8g7wA04 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.88 80.0 5.10e-01 100.0% 26.5%
1hyeA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.86 79.0 5.65e-01 100.0% 70.7%
2gn4B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.86 78.0 4.98e-01 100.0% 24.0%
6d9yA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.85 79.0 4.93e-01 100.0% 22.7%
3wtcA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.85 77.0 4.86e-01 100.0% 22.4%
1mldA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.85 76.0 5.54e-01 100.0% 67.6%
3u49D00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 77.0 4.88e-01 100.0% 24.8%
3fi9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 77.0 5.56e-01 100.0% 63.6%
5bt9D00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 77.0 4.87e-01 100.0% 24.2%
3pxxD00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 77.0 4.78e-01 100.0% 25.6%
4kzpB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 77.0 4.75e-01 100.0% 20.8%
3dhnA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 71.0 4.65e-01 100.0% 23.6%
8jatA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 76.0 5.08e-01 100.0% 31.1%
1yb1B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 77.0 4.92e-01 100.0% 24.7%
3v8bC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 76.0 4.81e-01 100.0% 22.7%
2hrzA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.83 75.0 4.86e-01 100.0% 25.7%
4y9dA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.83 76.0 4.86e-01 100.0% 24.7%
4zrmA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.83 72.0 4.78e-01 100.0% 25.9%
1yo6F00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.83 75.0 4.82e-01 100.0% 23.9%
2c20A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.83 72.0 4.76e-01 100.0% 25.6%
3gdgA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.82 74.0 4.65e-01 100.0% 23.2%
5t5qB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.82 74.0 4.78e-01 100.0% 24.3%
5if3B00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.82 71.0 4.71e-01 100.0% 25.4%
2yy7A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.82 70.0 4.29e-01 100.0% 16.7%
2b69A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.82 75.0 4.81e-01 100.0% 24.6%
8hi4A03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.81 73.0 4.87e-01 100.0% 33.3%
6vloD01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.81 74.0 4.87e-01 100.0% 27.1%
4bguA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.81 72.0 5.31e-01 100.0% 73.2%
6wjaA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.81 74.0 4.90e-01 100.0% 27.1%
1omzB00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.80 72.0 4.57e-01 100.0% 25.1%
3kzvA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 72.0 4.59e-01 100.0% 22.9%
7uqyB01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.80 71.0 4.72e-01 100.0% 29.0%
1k2wA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 73.0 4.58e-01 100.0% 21.5%
4yrbA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 68.0 4.54e-01 100.0% 25.2%
1hyhA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 72.0 5.26e-01 100.0% 68.8%
3m1aJ00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 72.0 4.52e-01 100.0% 20.6%
3tzqB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 72.0 4.61e-01 100.0% 22.9%
2xveA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.79 65.0 5.33e-01 98.2% 50.0%
2jl1A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.79 71.0 4.90e-01 100.0% 31.6%
4lw8A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.79 69.0 4.51e-01 100.0% 24.3%
4cr6A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.78 71.0 4.50e-01 100.0% 40.8%
2pzmB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.78 70.0 4.27e-01 100.0% 30.0%
3sxpA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.77 70.0 4.64e-01 100.0% 28.8%
6vr7A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.77 69.0 5.67e-01 100.0% 78.1%
1rkxA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.76 70.0 4.67e-01 100.0% 29.7%
3i6iA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.76 68.0 4.67e-01 100.0% 31.9%
4amuA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.76 67.0 4.76e-01 100.0% 59.5%
1aogA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.76 67.0 5.20e-01 100.0% 55.4%
3vpsB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.76 69.0 4.59e-01 100.0% 44.6%
2a35A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.76 67.0 4.50e-01 100.0% 41.8%
5dzsB02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 67.0 5.00e-01 100.0% 58.3%
2pbzA01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.74 63.0 5.51e-01 100.0% 63.4%
1iz0A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 67.0 4.76e-01 100.0% 46.8%
1k6jB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 63.0 4.32e-01 100.0% 27.2%
7mpyA01 3.20.20.20 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like 0.73 65.0 4.18e-01 100.0% 46.7%
4f3yA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 65.0 4.63e-01 100.0% 50.3%
3gmsA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 64.0 4.90e-01 100.0% 63.5%
4id9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.71 65.0 4.25e-01 100.0% 40.3%
1pg5A02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.71 60.0 4.51e-01 100.0% 61.5%
2x5oA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.71 62.0 5.27e-01 100.0% 78.3%
4ha7B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.70 62.0 4.17e-01 100.0% 28.8%
3a06B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 59.0 4.47e-01 100.0% 66.0%
3i42A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 60.0 4.70e-01 98.2% 48.3%
6rqaA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 59.0 4.24e-01 100.0% 45.3%
1ycoA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.68 58.0 3.73e-01 100.0% 29.0%
2gpjA02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.68 58.0 4.34e-01 100.0% 39.6%
1ad1A00 3.20.20.20 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like 0.67 59.0 3.77e-01 100.0% 49.2%
1ep3B02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.67 58.0 4.61e-01 100.0% 75.2%
3ctlA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.66 56.0 3.82e-01 100.0% 36.5%
4yhbA02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.66 56.0 4.31e-01 100.0% 45.5%
3qtgA03 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.65 55.0 4.45e-01 100.0% 47.8%
2yk4A01 3.30.370.20 Alpha Beta › 2-Layer Sandwich › Barnase; Chain D › 0.65 54.0 4.90e-01 100.0% 76.8%
1to6A01 3.40.50.10350 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycerate kinase; domain 1 0.63 52.0 4.01e-01 100.0% 47.2%
2zg6B01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.62 52.0 4.08e-01 100.0% 90.8%
3t38A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 50.0 3.93e-01 100.0% 65.6%
2czrA01 3.40.1350.70 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › TBP-interacting protein, N-terminal domain 0.58 42.0 3.56e-01 92.7% 42.5%
1d5rA01 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.56 44.0 3.33e-01 100.0% 78.7%
3sxuB00 3.40.50.10220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › DNA polymerase III, psi subunit 0.51 40.0 3.51e-01 100.0% 70.6%
ECOD (86)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3236286 2003.1.1.160 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3Beta_HSD, NmrA 0.91 82.0 4.83e-01 100.0% 14.9%
3869053 2003.1.1.160 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3Beta_HSD, NmrA 0.89 82.0 4.83e-01 100.0% 16.1%
3720307 2003.1.1.84 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › PRISE 0.88 77.0 4.56e-01 100.0% 14.1%
3698306 2003.1.1.84 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › PRISE 0.87 76.0 4.43e-01 100.0% 12.7%
3289259 2003.1.1.72 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GDP_Man_Dehyd 0.87 82.0 4.90e-01 100.0% 18.2%
4977997 2003.1.1.39 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_NADP 0.87 80.0 4.67e-01 100.0% 14.2%
4890171 2003.1.1.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Ldh_1_N 0.86 79.0 5.67e-01 100.0% 71.2%
3179983 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.86 79.0 4.60e-01 100.0% 16.9%
4060028 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.86 79.0 4.59e-01 100.0% 16.8%
1884917 2003.1.1.61 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR 0.85 77.0 4.86e-01 100.0% 29.3%
3296522 2003.1.1.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Ldh_1_N 0.85 77.0 5.25e-01 100.0% 53.0%
4126661 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.85 78.0 4.55e-01 100.0% 17.2%
3249612 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.85 73.0 4.71e-01 100.0% 22.1%
3179682 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.85 78.0 4.54e-01 100.0% 16.2%
4390123 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.85 75.0 4.71e-01 100.0% 20.4%
3264287 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.84 76.0 4.61e-01 100.0% 19.1%
3179879 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.84 73.0 4.75e-01 100.0% 23.1%
3189360 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.84 76.0 4.40e-01 100.0% 16.1%
3176314 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.84 71.0 4.35e-01 100.0% 16.7%
3688097 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.83 76.0 5.48e-01 100.0% 40.0%
4297122 2003.1.1.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_10 0.83 75.0 4.86e-01 100.0% 42.1%
3696405 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.83 76.0 4.40e-01 100.0% 16.6%
3956951 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.83 76.0 4.57e-01 100.0% 16.7%
3996219 2003.1.1.72 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GDP_Man_Dehyd 0.83 75.0 4.52e-01 100.0% 16.2%
4444241 2003.1.5.364 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAD_binding_4, Methyltransf_12 0.83 75.0 4.13e-01 100.0% 11.1%
3272240 2003.1.1.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_10 0.83 73.0 4.70e-01 100.0% 23.0%
3722044 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.82 75.0 4.85e-01 100.0% 24.4%
3626470 2003.1.1.72 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GDP_Man_Dehyd 0.82 74.0 4.55e-01 100.0% 35.1%
None — 0.82 74.0 5.37e-01 100.0% 69.0%
4146501 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.82 72.0 4.40e-01 100.0% 17.1%
4011439 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.82 75.0 4.77e-01 100.0% 24.7%
3574080 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.82 73.0 5.51e-01 100.0% 82.3%
1827834 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.82 71.0 4.88e-01 100.0% 29.6%
3179060 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.82 74.0 4.61e-01 100.0% 20.0%
3575322 2003.1.2.165 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › GDP_Man_Dehyd 0.81 74.0 6.31e-01 100.0% 71.8%
3809258 2003.1.1.84 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › PRISE 0.81 73.0 4.34e-01 100.0% 24.7%
3275849 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.81 73.0 4.29e-01 100.0% 18.7%
3596586 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.81 72.0 5.14e-01 100.0% 65.0%
3269600 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.81 72.0 4.24e-01 100.0% 17.4%
3728181 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.81 73.0 4.75e-01 100.0% 25.0%
3934410 2003.1.1.72 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GDP_Man_Dehyd 0.80 73.0 4.51e-01 100.0% 19.7%
3586704 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.80 68.0 4.06e-01 100.0% 14.0%
1734609 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.80 69.0 5.31e-01 100.0% 44.4%
3226175 2003.1.1.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3Beta_HSD 0.80 72.0 4.21e-01 100.0% 29.5%
1155277 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.80 73.0 6.13e-01 100.0% 61.8%
3696580 2003.1.1.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_4 0.80 71.0 4.14e-01 100.0% 15.8%
5058442 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.80 73.0 4.41e-01 100.0% 16.7%
4292213 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.80 72.0 4.66e-01 100.0% 40.0%
5028141 2003.1.1.72 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GDP_Man_Dehyd 0.80 72.0 4.38e-01 100.0% 18.4%
4608168 2003.1.1.62 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › HIM1 0.79 70.0 4.58e-01 100.0% 41.2%
4058774 2003.1.1.62 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › HIM1 0.79 71.0 4.60e-01 100.0% 38.2%
3226645 2003.1.1.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_10 0.79 70.0 4.60e-01 100.0% 41.3%
3784273 2003.1.2.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like 0.79 70.0 4.07e-01 100.0% 34.3%
4256384 2003.1.1.62 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › HIM1 0.78 70.0 4.55e-01 100.0% 39.6%
3443018 2003.1.1.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NmrA 0.78 70.0 4.63e-01 100.0% 32.4%
5001474 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.78 66.0 5.30e-01 100.0% 49.5%
3839726 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.78 71.0 4.29e-01 100.0% 20.6%
4146432 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.78 69.0 4.49e-01 100.0% 40.4%
5027765 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.78 66.0 5.23e-01 100.0% 47.3%
3654075 7516.1.1.21 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_64 0.77 68.0 4.35e-01 100.0% 22.6%
5076380 7516.1.1.10 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › CofC 0.77 69.0 4.58e-01 100.0% 36.2%
4552408 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.77 69.0 4.22e-01 100.0% 17.5%
9108 2003.1.1.62 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › HIM1 0.76 67.0 4.50e-01 100.0% 41.8%
3594633 7516.1.1.0 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.74 64.0 4.28e-01 100.0% 30.7%
4546037 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.74 62.0 3.82e-01 100.0% 16.0%
4928728 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.74 64.0 4.67e-01 96.4% 42.8%
4974804 7512.1.1.139 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › DUF1972 0.74 64.0 4.44e-01 96.4% 66.9%
2640332 3979.1.1.0 ↗ a+b four layers › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain 0.73 58.0 3.62e-01 90.9% 15.8%
3164506 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.73 63.0 3.97e-01 100.0% 21.0%
4955676 7512.1.1.32 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4 0.72 62.0 4.42e-01 100.0% 33.7%
3286098 7512.1.1.20 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › EryCIII-like_C 0.71 64.0 4.40e-01 100.0% 43.9%
2604197 7514.1.1.2 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › SIP 0.69 60.0 4.70e-01 100.0% 47.1%
2602554 7510.1.1.0 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like 0.68 58.0 4.66e-01 100.0% 69.6%
2600703 7514.1.1.2 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › SIP 0.68 58.0 4.33e-01 100.0% 39.3%
3954527 7514.1.1.2 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › SIP 0.68 58.0 4.23e-01 100.0% 41.1%
5038037 2006.1.2.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases 0.67 57.0 3.97e-01 100.0% 37.0%
3931605 7512.1.1.1 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.67 56.0 3.65e-01 100.0% 35.3%
3720354 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.67 54.0 3.48e-01 96.4% 31.0%
3346202 7516.1.1.0 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.66 57.0 3.57e-01 100.0% 29.0%
5045191 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.66 55.0 3.99e-01 100.0% 55.6%
4947551 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.66 56.0 3.82e-01 100.0% 38.2%
3371194 7501.1.1.0 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.65 53.0 3.70e-01 100.0% 38.3%
3671526 7516.1.1.0 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.64 54.0 3.82e-01 100.0% 46.9%
3387176 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.64 54.0 3.88e-01 100.0% 41.1%
4992167 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.55 44.0 2.61e-01 92.7% 11.8%
2984780 7512.1.1.16 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Capsule_synth 0.55 45.0 3.28e-01 100.0% 47.8%