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hypothetical_protein_VARVgp178

Euk-Vir

Variola_virus

hypothetical_protein_VARVgp178__NP_042222__Variola_virus__10255

Identity

Accession:
NP_042222 ↗
Protein ID:
hypothetical_protein_VARVgp178
Kingdom:
euk

Quality

75.7 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Variola_virus

TaxID: 10255

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 40-97
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 54.0 5.18e-01 77.6% 77.6%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 53.0 5.02e-01 77.6% 75.4%
3dmqA08 6.10.140.1500 Special › Helix non-globular › Helix Hairpins › 0.71 47.0 4.24e-01 75.9% 50.0%
2c2lA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.70 49.0 3.78e-01 74.1% 34.6%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 51.0 4.20e-01 77.6% 49.5%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.67 47.0 4.62e-01 75.9% 76.6%
3wd6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 45.0 3.55e-01 70.7% 35.6%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 47.0 4.52e-01 82.8% 76.5%
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 53.0 4.75e-01 98.3% 89.3%
1vw4L01 3.90.1030.10 Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 0.62 42.0 3.14e-01 70.7% 36.3%
1iurA01 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.61 41.0 4.02e-01 70.7% 63.5%
3fm9A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 43.0 3.94e-01 86.2% 56.4%
4r6hA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.60 48.0 3.24e-01 89.7% 80.6%
2oo2A00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.59 46.0 4.26e-01 86.2% 80.3%
4l8eA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 41.0 3.43e-01 74.1% 44.5%
4mspB02 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 35.0 3.31e-01 84.5% 45.3%
5nl9A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 41.0 3.68e-01 75.9% 82.1%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.57 43.0 4.09e-01 82.8% 72.1%
1sfxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 48.0 4.03e-01 100.0% 68.3%
2g7rA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.55 47.0 4.21e-01 98.3% 93.0%
1e9fA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 42.0 3.02e-01 89.7% 37.1%
2hszA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 39.0 3.64e-01 77.6% 66.7%
2bbwA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 38.0 2.68e-01 86.2% 20.9%
6cgvM01 1.20.120.1500 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pre-hexon-linking protein IIIa 0.53 41.0 3.36e-01 94.8% 88.8%
4tktA02 1.10.1240.100 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.51 37.0 3.37e-01 79.3% 74.4%
3r0qA02 2.70.160.11 Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 0.51 37.0 2.63e-01 81.0% 89.9%
4dbgB02 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.50 41.0 4.04e-01 87.9% 83.6%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4527588 3755.1.1.25 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › H-kinase_dim 0.67 49.0 4.03e-01 77.6% 85.7%
4027348 592.7.1.0 ↗ alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain 0.65 43.0 4.07e-01 70.7% 69.3%
5057946 3960.1.1.0 ↗ alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain 0.63 45.0 3.72e-01 81.0% 41.9%
4674043 632.11.1.12 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › UVR 0.62 45.0 4.00e-01 81.0% 86.7%
4260268 2006.1.1.44 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like 0.61 43.0 2.88e-01 86.2% 20.0%
3960907 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 46.0 2.87e-01 82.8% 16.9%
5039859 6035.1.1.0 ↗ alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain 0.60 43.0 3.71e-01 75.9% 54.4%
4119015 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.60 43.0 4.29e-01 77.6% 88.3%
None — 0.59 46.0 2.84e-01 84.5% 16.7%
3614578 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.58 43.0 3.85e-01 81.0% 68.2%
3883209 2004.1.1.41 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADK 0.58 42.0 2.81e-01 81.0% 19.6%
3778748 2004.1.1.41 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADK 0.56 40.0 2.77e-01 79.3% 33.2%
3922168 101.1.1.21 ↗ alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 0.55 36.0 3.41e-01 74.1% 55.7%
4967950 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 40.0 3.45e-01 79.3% 81.1%
3196401 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.53 40.0 4.17e-01 81.0% 83.6%
3990160 2004.1.1.41 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADK 0.53 39.0 3.31e-01 82.8% 46.3%
3659978 101.1.1.138 ↗ alpha arrays › HTH › HTH › Three-helical HTH › GeBP-like_DBD 0.51 45.0 3.80e-01 96.6% 61.1%
4979742 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.51 36.0 3.28e-01 75.9% 58.7%