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hypothetical_protein_pdul_cds_1024
Euk-VirPandoravirus_dulcis
hypothetical_protein_pdul_cds_1024__YP_008319964__Pandoravirus_dulcis__1349409
Identity
- Accession:
- YP_008319964 ↗
- Protein ID:
- hypothetical_protein_pdul_cds_1024
- Kingdom:
- euk
Quality
63.3
mean pLDDT
Cluster
View cluster (16 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 491-552
D2
medium
residues 53-108_122-150_165-246
D3
medium
residues 247-370
Domain cluster:
rep: hypothetical_protein_pmac_cds_886__YP_009481570__Pandoravirus_macleodensis__2107707__D211-322
CATH (61)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.76 | 62.0 | 5.92e-01 | 85.5% | 88.1% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.74 | 56.0 | 5.19e-01 | 79.0% | 82.2% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.73 | 46.0 | 5.64e-01 | 82.3% | 98.8% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.73 | 57.0 | 4.22e-01 | 82.3% | 77.9% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.72 | 56.0 | 4.40e-01 | 81.5% | 86.5% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.71 | 55.0 | 5.80e-01 | 96.0% | 92.6% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.71 | 55.0 | 6.03e-01 | 85.5% | 99.0% |
| 3rvyA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.71 | 36.0 | 3.79e-01 | 100.0% | 54.4% |
| 1nu7D01 | 1.20.120.750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 | 0.69 | 52.0 | 5.09e-01 | 78.2% | 94.1% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 51.0 | 4.24e-01 | 77.4% | 72.4% |
| 6okdA03 | 1.20.930.40 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain | 0.68 | 61.0 | 5.89e-01 | 96.0% | 100.0% |
| 3unvA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.68 | 54.0 | 3.93e-01 | 82.3% | 41.9% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 59.0 | 4.86e-01 | 92.7% | 96.3% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 51.0 | 4.45e-01 | 80.6% | 95.2% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.66 | 52.0 | 4.50e-01 | 82.3% | 70.7% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.66 | 52.0 | 4.74e-01 | 82.3% | 91.9% |
| 3bvxA02 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.66 | 51.0 | 5.40e-01 | 81.5% | 90.1% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.65 | 57.0 | 4.70e-01 | 96.0% | 86.5% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 40.0 | 4.59e-01 | 96.0% | 81.2% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.64 | 42.0 | 4.97e-01 | 76.6% | 98.8% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.64 | 47.0 | 4.55e-01 | 76.6% | 68.6% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 46.0 | 4.55e-01 | 76.6% | 75.4% |
| 3wfdB00 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.63 | 57.0 | 3.86e-01 | 98.4% | 35.0% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.63 | 47.0 | 4.40e-01 | 81.5% | 64.2% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 48.0 | 4.64e-01 | 80.6% | 83.3% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 47.0 | 4.78e-01 | 85.5% | 81.7% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.61 | 42.0 | 4.47e-01 | 87.9% | 80.0% |
| 4lqqB00 | 1.20.140.30 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › MOB kinase activator | 0.61 | 46.0 | 4.33e-01 | 79.8% | 65.8% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 44.0 | 4.55e-01 | 76.6% | 78.2% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 46.0 | 3.61e-01 | 80.6% | 99.6% |
| 3mk7A00 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.61 | 54.0 | 3.66e-01 | 98.4% | 32.0% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.60 | 40.0 | 4.19e-01 | 78.2% | 72.8% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 49.0 | 4.09e-01 | 86.3% | 86.7% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 46.0 | 4.76e-01 | 79.8% | 92.3% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.60 | 50.0 | 5.08e-01 | 96.0% | 94.3% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.60 | 39.0 | 3.85e-01 | 80.6% | 61.7% |
| 1pw4A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.58 | 50.0 | 4.23e-01 | 95.2% | 85.4% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 41.0 | 4.19e-01 | 75.0% | 82.3% |
| 7xrxB01 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.58 | 44.0 | 3.16e-01 | 81.5% | 58.8% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.58 | 51.0 | 4.43e-01 | 98.4% | 89.7% |
| 2x1lA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 43.0 | 3.86e-01 | 77.4% | 58.1% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 42.0 | 4.59e-01 | 76.6% | 100.0% |
| 4iu9B01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 44.0 | 3.70e-01 | 84.7% | 86.6% |
| 6gyhA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 45.0 | 3.75e-01 | 87.9% | 48.0% |
| 4k5yA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 41.0 | 3.28e-01 | 84.7% | 39.1% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 41.0 | 4.56e-01 | 84.7% | 98.0% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 43.0 | 4.48e-01 | 82.3% | 86.4% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.55 | 48.0 | 3.58e-01 | 98.4% | 85.2% |
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.55 | 42.0 | 4.19e-01 | 79.8% | 89.8% |
| 1td6A03 | 1.10.472.40 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 | 0.54 | 34.0 | 3.89e-01 | 98.4% | 84.8% |
| 3pf0A00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.54 | 44.0 | 3.28e-01 | 87.9% | 81.1% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 39.0 | 4.35e-01 | 100.0% | 93.1% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 44.0 | 4.07e-01 | 93.5% | 69.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.54 | 37.0 | 3.90e-01 | 78.2% | 77.9% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.53 | 40.0 | 4.34e-01 | 78.2% | 99.0% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.53 | 36.0 | 3.63e-01 | 71.8% | 70.2% |
| 3dytA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 43.0 | 3.72e-01 | 87.1% | 97.9% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.52 | 34.0 | 4.14e-01 | 80.6% | 100.0% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 37.0 | 4.10e-01 | 75.0% | 94.1% |
| 2e8gA01 | 1.20.1440.150 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.51 | 39.0 | 4.00e-01 | 83.1% | 87.1% |
| 4uiqB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 35.0 | 3.30e-01 | 71.0% | 82.4% |
ECOD (67)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3965610 | 3831.1.1.1 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI | 0.82 | 55.0 | 6.60e-01 | 71.8% | 100.0% |
| 4403218 | 3291.1.1.82 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING | 0.77 | 39.0 | 4.24e-01 | 96.8% | 58.1% |
| 3286912 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.77 | 53.0 | 5.98e-01 | 75.8% | 91.6% |
| 4131078 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.75 | 48.0 | 5.88e-01 | 73.4% | 100.0% |
| 4101843 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.75 | 52.0 | 5.68e-01 | 80.6% | 84.8% |
| 3716257 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.74 | 54.0 | 5.22e-01 | 74.2% | 96.3% |
| 4653531 | 632.1.1.14 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › EzrA | 0.74 | 56.0 | 5.90e-01 | 78.2% | 98.2% |
| 5083938 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.73 | 66.0 | 5.62e-01 | 96.0% | 93.7% |
| 3286925 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.72 | 52.0 | 5.27e-01 | 73.4% | 85.0% |
| 4142346 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.70 | 41.0 | 4.36e-01 | 97.6% | 65.5% |
| 3345599 | 601.16.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 | 0.67 | 51.0 | 4.53e-01 | 80.6% | 72.8% |
| 3569902 | 604.5.1.43 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › Clusterin | 0.66 | 60.0 | 5.68e-01 | 96.8% | 90.3% |
| 3984201 | 192.2.1.73 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › MscS_porin | 0.66 | 61.0 | 4.02e-01 | 97.6% | 70.7% |
| 5065166 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.65 | 58.0 | 4.81e-01 | 96.8% | 82.9% |
| 3641083 | 4323.1.1.8 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › NET2A | 0.64 | 56.0 | 4.87e-01 | 96.8% | 75.9% |
| 3222708 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.64 | 56.0 | 3.64e-01 | 97.6% | 37.2% |
| 4940393 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.63 | 55.0 | 4.43e-01 | 96.8% | 74.4% |
| 3554799 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.63 | 44.0 | 4.48e-01 | 73.4% | 72.0% |
| 3973749 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.62 | 56.0 | 4.78e-01 | 100.0% | 95.1% |
| 4028318 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 45.0 | 4.55e-01 | 77.4% | 74.4% |
| 5052002 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.62 | 53.0 | 4.47e-01 | 93.5% | 87.9% |
| 3340407 | 611.7.1.14 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7792 | 0.62 | 54.0 | 4.97e-01 | 96.0% | 92.5% |
| 3353167 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.62 | 51.0 | 3.26e-01 | 91.1% | 29.3% |
| 3179320 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 54.0 | 4.46e-01 | 96.0% | 81.8% |
| 3821144 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.61 | 50.0 | 3.17e-01 | 87.9% | 39.5% |
| 3224861 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 44.0 | 4.41e-01 | 75.8% | 86.2% |
| 5049263 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 53.0 | 4.50e-01 | 96.0% | 86.2% |
| 3882066 | 3291.1.1.124 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Bap31 | 0.61 | 45.0 | 4.07e-01 | 75.8% | 77.6% |
| 4026128 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.61 | 50.0 | 4.73e-01 | 88.7% | 94.7% |
| 5038580 | 633.21.1.1 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 | 0.61 | 41.0 | 4.43e-01 | 76.6% | 81.9% |
| 4954957 | 3646.1.1.1 ↗ | alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › CbiQ | 0.60 | 44.0 | 3.49e-01 | 75.8% | 80.8% |
| 3231196 | 5001.1.1.16 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt | 0.60 | 47.0 | 3.56e-01 | 83.1% | 91.7% |
| 3948847 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 47.0 | 5.21e-01 | 87.1% | 100.0% |
| 3643152 | 611.7.1.11 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 | 0.60 | 53.0 | 5.23e-01 | 96.0% | 95.4% |
| 3948661 | 3860.1.1.167 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › MscS_porin | 0.59 | 53.0 | 3.72e-01 | 97.6% | 76.2% |
| 3790435 | 601.16.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C | 0.59 | 39.0 | 3.86e-01 | 71.8% | 62.3% |
| 5038471 | 633.21.1.1 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 | 0.59 | 43.0 | 4.49e-01 | 85.5% | 81.7% |
| 4981135 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.59 | 51.0 | 4.30e-01 | 92.7% | 56.6% |
| 3616117 | 601.1.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C | 0.59 | 39.0 | 3.98e-01 | 73.4% | 68.3% |
| 5040281 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.59 | 52.0 | 4.35e-01 | 94.4% | 57.1% |
| 5032686 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 51.0 | 4.46e-01 | 96.8% | 90.8% |
| 3946585 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 50.0 | 4.24e-01 | 96.0% | 82.8% |
| 3830361 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.58 | 50.0 | 4.66e-01 | 92.7% | 82.6% |
| 3431415 | 6155.1.1.6 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 | 0.58 | 36.0 | 4.33e-01 | 72.6% | 91.8% |
| 2722819 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.58 | 48.0 | 3.83e-01 | 87.9% | 84.3% |
| 4515899 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 35.0 | 3.16e-01 | 96.0% | 43.5% |
| 3189761 | 5050.1.1.12 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 | 0.57 | 50.0 | 3.83e-01 | 100.0% | 94.0% |
| 3742018 | 7094.1.1.2 ↗ | alpha bundles › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › LIS_MGM1 | 0.57 | 37.0 | 4.20e-01 | 95.2% | 85.3% |
| 3810254 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.57 | 49.0 | 4.48e-01 | 91.1% | 78.8% |
| 4964622 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.57 | 51.0 | 4.29e-01 | 98.4% | 58.7% |
| 3478731 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.57 | 41.0 | 3.63e-01 | 75.0% | 80.5% |
| 4939024 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.57 | 50.0 | 4.27e-01 | 96.0% | 72.2% |
| 4952960 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 50.0 | 4.24e-01 | 95.2% | 74.9% |
| 4933874 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 48.0 | 4.13e-01 | 93.5% | 59.0% |
| 5012473 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.55 | 40.0 | 4.22e-01 | 96.8% | 82.7% |
| 3613386 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.55 | 50.0 | 3.77e-01 | 100.0% | 46.9% |
| 3828167 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.55 | 48.0 | 4.42e-01 | 95.2% | 80.6% |
| 4929535 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.55 | 51.0 | 4.19e-01 | 100.0% | 91.6% |
| 3990051 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.54 | 47.0 | 4.03e-01 | 97.6% | 77.9% |
| 3852832 | 3922.1.1.72 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › FAM186A-B_C | 0.54 | 40.0 | 3.78e-01 | 77.4% | 94.0% |
| 3806047 | 5050.1.1.26 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot | 0.54 | 47.0 | 3.75e-01 | 98.4% | 81.9% |
| 3767783 | 192.2.1.19 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › FAM186A-B_C | 0.54 | 40.0 | 3.76e-01 | 77.4% | 94.0% |
| 5073361 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.53 | 47.0 | 4.02e-01 | 96.8% | 80.0% |
| 4927111 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.52 | 46.0 | 3.82e-01 | 95.2% | 57.6% |
| 3935598 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 44.0 | 3.75e-01 | 97.6% | 90.5% |
| 3937968 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 46.0 | 4.18e-01 | 97.6% | 89.1% |
| 4177936 | 2004.1.1.929 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › FliJ | 0.50 | 39.0 | 2.76e-01 | 83.1% | 31.5% |
D4
medium
residues 371-427
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.77 | 62.0 | 5.29e-01 | 84.2% | 61.6% |
| 1k92A02 | 3.90.1260.10 | Alpha Beta › Alpha-Beta Complex › Argininosuccinate synthetase, chain A, domain 2 › Argininosuccinate synthetase, chain A, domain 2 | 0.60 | 41.0 | 2.85e-01 | 73.7% | 51.2% |
| 5eufA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.59 | 47.0 | 3.28e-01 | 86.0% | 67.4% |
| 1miwA04 | 1.10.246.80 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.54 | 35.0 | 3.38e-01 | 71.9% | 57.8% |