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hypothetical_protein_pneo_cds_849

Euk-Vir

Pandoravirus_neocaledonia

hypothetical_protein_pneo_cds_849__YP_009482459__Pandoravirus_neocaledonia__2107708

Identity

Accession:
YP_009482459 ↗
Protein ID:
hypothetical_protein_pneo_cds_849
Kingdom:
euk

Quality

72.6 mean pLDDT

Taxonomy

TaxID: 2107708

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 20-94
PDB
D2 medium residues 95-150
PDB
Domain cluster: representative
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hiaA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.88 73.0 4.93e-01 91.1% 27.8%
1l0oA00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.86 66.0 4.84e-01 82.1% 33.3%
4ex8A00 3.40.1790.10 Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain 0.80 62.0 3.83e-01 87.5% 15.6%
2d2mD00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.79 58.0 4.23e-01 83.9% 30.3%
3bg2A01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.77 69.0 4.72e-01 100.0% 33.9%
1tfeA02 1.10.286.20 Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › 0.76 57.0 6.14e-01 94.6% 100.0%
6oi7A01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.76 69.0 4.62e-01 100.0% 34.7%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 53.0 4.06e-01 80.4% 33.6%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.73 60.0 4.43e-01 91.1% 77.9%
5k2xA00 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.73 65.0 3.82e-01 98.2% 87.7%
3spcA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 62.0 4.86e-01 100.0% 80.3%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 51.0 3.94e-01 75.0% 40.7%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 52.0 4.30e-01 80.4% 50.0%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 52.0 4.37e-01 82.1% 47.9%
3qnmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.69 54.0 4.68e-01 91.1% 54.4%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 54.0 4.88e-01 87.5% 84.6%
2yx8A00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.68 59.0 5.23e-01 96.4% 66.7%
3fd0A01 3.90.1150.60 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Methioning gamme-lyase, C-terminal domain 0.68 58.0 4.04e-01 98.2% 45.6%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.67 57.0 4.95e-01 94.6% 60.9%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.67 53.0 4.05e-01 85.7% 72.2%
1gjsA00 1.10.8.40 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Albumin-binding domain 0.67 51.0 4.93e-01 87.5% 73.8%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.66 50.0 4.42e-01 83.9% 56.2%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.66 57.0 5.41e-01 100.0% 83.8%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.66 56.0 3.25e-01 94.6% 81.2%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.66 52.0 4.79e-01 87.5% 97.3%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.66 58.0 5.33e-01 100.0% 75.7%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 52.0 5.03e-01 87.5% 82.8%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 48.0 4.13e-01 80.4% 50.0%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.66 44.0 4.28e-01 71.4% 62.9%
4k7cA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.66 58.0 3.49e-01 100.0% 14.5%
2aswA00 1.10.8.500 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › HAMP domain in histidine kinase 0.65 38.0 3.89e-01 76.8% 58.9%
2go7A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.65 48.0 4.58e-01 80.4% 100.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 56.0 4.88e-01 98.2% 98.8%
3bg2A03 1.10.3410.10 Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain 0.64 55.0 4.67e-01 98.2% 57.3%
1vibA00 1.10.287.120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like 0.64 49.0 4.99e-01 92.9% 90.9%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.64 56.0 3.42e-01 94.6% 17.3%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.64 52.0 4.73e-01 92.9% 66.7%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.63 53.0 4.57e-01 96.4% 58.7%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 54.0 3.84e-01 98.2% 69.8%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 51.0 3.88e-01 92.9% 55.2%
3b0cW00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.63 54.0 4.92e-01 100.0% 72.6%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 51.0 4.16e-01 92.9% 72.9%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.62 50.0 4.76e-01 91.1% 79.4%
3fgrA02 1.10.439.20 Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 0.61 52.0 4.04e-01 96.4% 66.4%
3jrqA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.61 52.0 3.35e-01 98.2% 47.2%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.60 49.0 4.08e-01 100.0% 92.2%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.60 54.0 4.21e-01 96.4% 50.0%
3bemB00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.60 52.0 3.56e-01 100.0% 60.3%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.59 49.0 4.15e-01 98.2% 53.5%
1rp3G02 1.20.140.160 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain 0.58 49.0 3.66e-01 92.9% 54.9%
3vayA02 1.20.120.1600 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 51.0 4.40e-01 100.0% 97.7%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.57 46.0 4.81e-01 91.1% 100.0%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 49.0 3.74e-01 92.9% 48.3%
3fkjA02 1.10.10.2240 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.52 39.0 3.76e-01 82.1% 76.6%
3euaA02 1.10.10.2240 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.51 38.0 3.72e-01 82.1% 76.6%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4978292 3542.1.1.1 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin 0.90 82.0 5.06e-01 100.0% 20.4%
3436965 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.90 81.0 6.74e-01 100.0% 67.4%
3739839 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.89 81.0 6.40e-01 100.0% 51.8%
3632302 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.89 75.0 6.59e-01 91.1% 63.7%
3261624 3470.1.1.0 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain 0.89 74.0 7.73e-01 89.3% 100.0%
3482541 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.88 80.0 5.00e-01 100.0% 20.7%
3455488 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.88 76.0 7.50e-01 96.4% 91.7%
3347379 3470.1.1.26 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › DUF543 0.88 79.0 7.52e-01 100.0% 87.7%
4013204 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.88 80.0 4.48e-01 96.4% 91.9%
3174728 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.87 79.0 4.87e-01 100.0% 19.1%
3698416 844.1.1.0 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain 0.86 74.0 4.71e-01 91.1% 65.4%
3401669 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.86 78.0 4.77e-01 100.0% 19.3%
3999314 5058.1.1.35 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › EMC6 0.86 76.0 6.86e-01 100.0% 73.3%
4964420 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.85 76.0 6.06e-01 100.0% 52.7%
3904347 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.85 69.0 6.19e-01 87.5% 66.7%
3482882 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.84 73.0 7.18e-01 94.6% 88.3%
4103905 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.84 75.0 4.81e-01 100.0% 22.8%
4971237 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.83 75.0 5.95e-01 100.0% 53.6%
3692508 4120.1.1.0 few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP 0.83 76.0 6.20e-01 100.0% 64.0%
3515411 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.82 70.0 4.68e-01 94.6% 26.3%
4149728 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.82 73.0 6.47e-01 100.0% 70.0%
4937236 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.82 72.0 5.95e-01 100.0% 59.0%
2832675 2006.1.4.8 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_5 0.82 73.0 4.90e-01 100.0% 29.3%
3833866 2004.1.1.24 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C 0.82 73.0 4.03e-01 100.0% 7.6%
3649222 2004.1.1.23 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.81 73.0 4.39e-01 100.0% 16.6%
4964132 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.79 69.0 5.68e-01 100.0% 54.3%
3643105 6026.1.1.1 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.79 69.0 4.97e-01 98.2% 34.8%
4930860 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.79 70.0 5.97e-01 100.0% 64.4%
5079588 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.79 64.0 5.52e-01 91.1% 58.9%
5040955 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.79 70.0 5.67e-01 100.0% 55.2%
4597483 5058.1.1.1 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.79 68.0 5.36e-01 100.0% 48.3%
3882597 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.78 69.0 5.90e-01 100.0% 76.7%
3392260 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.78 70.0 6.51e-01 100.0% 82.9%
4996722 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.78 68.0 5.76e-01 100.0% 64.2%
4358519 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.77 67.0 5.58e-01 100.0% 57.0%
4317794 5058.1.1.1 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st 0.77 67.0 5.48e-01 100.0% 58.1%
5012687 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.77 67.0 5.66e-01 100.0% 61.1%
2983215 1131.1.1.1 extended segments › Mitochondrial complex I, B14.5b subunit › Mitochondrial complex I, B14.5b subunit › Mitochondrial complex I, B14.5b subunit › NDUF_C2 0.77 69.0 5.40e-01 100.0% 50.4%
3961186 103.9.1.0 alpha arrays › RuvA-C › RanGAP2 N-terminal domain › RanGAP2 N-terminal domain 0.76 68.0 5.62e-01 100.0% 61.0%
5071140 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.76 68.0 4.95e-01 100.0% 39.3%
3299872 5063.1.1.3 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › NADH-u_ox-rdase 0.76 62.0 5.42e-01 96.4% 60.0%
4031085 3826.1.1.79 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › DUF1024 0.76 59.0 5.30e-01 100.0% 60.3%
5052081 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.76 67.0 4.81e-01 100.0% 37.6%
5022551 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.76 67.0 5.26e-01 100.0% 51.7%
4024271 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.76 67.0 5.05e-01 100.0% 65.9%
4981035 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.75 66.0 6.33e-01 100.0% 89.2%
3516870 5094.1.1.0 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like 0.75 67.0 5.45e-01 100.0% 57.1%
4276746 192.1.1.40 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › VMA21 0.75 64.0 6.07e-01 98.2% 80.9%
3589830 5043.2.1.8 extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain › DUF5592 0.74 65.0 6.09e-01 100.0% 91.4%
5055969 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.74 64.0 5.44e-01 100.0% 63.2%
4961990 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.74 62.0 4.63e-01 100.0% 37.4%
4979243 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.74 64.0 4.26e-01 100.0% 65.7%
3721541 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.73 62.0 5.22e-01 98.2% 56.0%
4318142 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.73 63.0 4.73e-01 98.2% 40.7%
4942389 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.73 63.0 5.41e-01 100.0% 61.3%
5066143 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.73 63.0 5.78e-01 100.0% 76.0%
3218140 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.73 63.0 4.00e-01 98.2% 55.7%
5039692 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.72 61.0 5.26e-01 100.0% 62.1%
4012810 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.71 60.0 5.34e-01 98.2% 64.7%
3967002 3843.1.1.27 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › COX4_pro 0.71 60.0 5.30e-01 96.4% 63.5%
5017842 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.70 60.0 5.24e-01 96.4% 69.4%
3988424 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.69 60.0 5.72e-01 98.2% 86.2%
4554416 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.69 59.0 5.08e-01 94.6% 61.1%
4180835 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.69 60.0 5.66e-01 100.0% 82.9%
4944477 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.69 56.0 3.98e-01 96.4% 28.6%
3988447 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.68 58.0 5.90e-01 98.2% 100.0%
3816255 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 58.0 3.89e-01 100.0% 34.8%
4370184 3758.2.1.1 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.68 59.0 4.17e-01 100.0% 31.5%
4683346 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.67 59.0 5.28e-01 100.0% 72.2%
3335568 160.1.1.1 alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_ab_C 0.67 54.0 4.53e-01 92.9% 56.0%
2674763 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.66 58.0 5.32e-01 100.0% 74.7%
4107823 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.65 55.0 4.67e-01 100.0% 56.0%
3732913 316.1.1.11 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › GrpB 0.63 46.0 3.29e-01 82.1% 25.1%
3487879 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.63 54.0 4.79e-01 100.0% 67.1%
4081214 605.1.1.290 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Phage_Nu1 0.62 52.0 4.91e-01 94.6% 78.6%
D3 medium residues 151-229
PDB
Domain cluster: representative
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ogcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.67 48.0 3.58e-01 93.7% 30.6%
8amzP01 1.25.40.570 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 58.0 3.70e-01 100.0% 25.1%
2xq0A03 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.63 52.0 4.22e-01 92.4% 94.3%
8hk0A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.62 55.0 4.80e-01 98.7% 100.0%
1kqfA02 3.40.50.740 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 52.0 3.75e-01 94.9% 97.1%
3mekA04 1.25.40.970 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 48.0 4.88e-01 98.7% 85.0%
3wuhA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 41.0 3.22e-01 93.7% 32.1%
4gyoB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 45.0 3.78e-01 98.7% 45.3%
1ug3A01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 52.0 3.96e-01 100.0% 75.4%
2jbyA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.60 46.0 4.02e-01 96.2% 53.5%
4iv6B01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.59 50.0 4.47e-01 96.2% 75.0%
7b00A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.59 45.0 2.87e-01 84.8% 53.0%
1bucA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.58 49.0 4.29e-01 96.2% 70.7%
4dvgB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 47.0 3.31e-01 98.7% 39.3%
4i1eA03 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.55 46.0 3.86e-01 93.7% 95.7%
1gy8B01 3.90.25.10 Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1 0.55 40.0 3.47e-01 87.3% 48.8%
1beoA00 1.10.239.10 Mainly Alpha › Orthogonal Bundle › Beta-cryptogein › Elicitin domain 0.55 40.0 3.75e-01 81.0% 62.2%
4jhrB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 43.0 2.95e-01 98.7% 23.2%
2xzeB00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 48.0 4.05e-01 100.0% 57.2%
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 48.0 3.40e-01 100.0% 42.1%
5u4qB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 48.0 3.24e-01 100.0% 43.1%
4m9aA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.54 44.0 3.97e-01 94.9% 70.6%
2z0fA03 3.40.120.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 0.54 41.0 3.60e-01 97.5% 53.3%
4v19K02 1.10.10.250 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L11/L12, C-terminal domain 0.54 44.0 4.54e-01 92.4% 100.0%
2c9kA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.53 45.0 3.32e-01 98.7% 75.7%
5z2mB00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.53 47.0 3.92e-01 98.7% 73.0%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.53 43.0 3.92e-01 98.7% 64.3%
1oy5A01 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.53 41.0 3.32e-01 84.8% 41.6%
1gs0A01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.53 40.0 3.47e-01 83.5% 71.3%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.52 43.0 3.29e-01 92.4% 83.2%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 44.0 3.92e-01 98.7% 63.6%
4fe7A03 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.52 45.0 4.11e-01 100.0% 74.3%
3e99A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 42.0 3.40e-01 87.3% 97.3%
3cexA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.51 38.0 2.98e-01 78.5% 65.9%
3oioA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.51 44.0 3.98e-01 100.0% 72.3%
5c9iD01 1.10.439.10 Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Penicillin Amidohydrolase, domain 1 0.51 43.0 3.48e-01 94.9% 70.8%
5tgfD00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.51 43.0 2.95e-01 98.7% 79.2%
5lnxF01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 42.0 3.78e-01 96.2% 68.6%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.50 44.0 4.20e-01 100.0% 88.2%
2r31A02 1.10.3580.10 Mainly Alpha › Orthogonal Bundle › ATP12-like fold › ATP12 ATPase 0.50 38.0 2.99e-01 81.0% 82.9%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4306590 109.40.1.1 alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Hira 0.71 62.0 4.94e-01 94.9% 51.6%
3476724 109.40.1.1 alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Hira 0.68 59.0 4.72e-01 96.2% 52.3%
3723994 109.4.1.1934 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_14, TPR_16 0.67 48.0 3.30e-01 93.7% 21.8%
3818560 109.4.1.32 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G 0.64 56.0 4.26e-01 100.0% 74.9%
3546037 5067.1.1.19 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › CLAMP 0.63 51.0 4.12e-01 87.3% 48.0%
3755136 545.1.1.2 alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27 › CLAMP 0.63 51.0 4.20e-01 87.3% 51.4%
4029259 3273.1.1.4 alpha arrays › Filamentous archaeal viruses coat proteins › Filamentous archaeal viruses coat proteins › Filamentous archaeal viruses coat proteins › CLAMP 0.62 50.0 4.41e-01 87.3% 61.7%
4186195 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.61 46.0 3.50e-01 83.5% 73.3%
5066757 304.128.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB › FtsX 0.61 49.0 3.59e-01 87.3% 51.6%
3610794 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 3.80e-01 100.0% 74.3%
3262061 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.61 54.0 4.42e-01 100.0% 86.9%
3572552 109.4.1.908 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DOP1 0.60 53.0 3.71e-01 100.0% 70.7%
3655716 544.1.1.1 alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Prp18 0.60 48.0 4.33e-01 87.3% 75.5%
3204866 109.54.1.12 alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › PF28770 0.60 54.0 3.53e-01 97.5% 43.1%
3680927 3542.1.1.3 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B 0.59 45.0 3.08e-01 84.8% 74.2%
1563105 109.4.1.89 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Drf_FH3,Drf_GBD 0.56 47.0 3.31e-01 98.7% 39.3%
3743916 109.3.1.96 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.56 47.0 3.64e-01 89.9% 61.8%
4014401 544.1.1.0 alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 0.56 46.0 3.60e-01 92.4% 47.8%
3958815 129.1.1.0 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.56 42.0 3.45e-01 82.3% 51.0%
3696838 109.4.1.1646 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Foie-gras_1, PF29907 0.56 44.0 3.43e-01 89.9% 54.4%
3423860 148.1.3.207 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF7751 0.56 34.0 3.33e-01 84.8% 56.5%
3896924 320.4.1.5 a+b two layers › R3H domain-like › PUB domain › PUB domain › Gasdermin_C 0.55 44.0 3.38e-01 89.9% 83.4%
3406152 109.4.1.587 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mon2_C 0.55 47.0 3.53e-01 100.0% 64.2%
3614448 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.54 45.0 2.99e-01 97.5% 81.8%
3191119 10.12.1.101 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › JmjC, Cupin_8 0.54 46.0 3.02e-01 96.2% 53.3%
3717835 3069.1.1.0 alpha arrays › BART › BART › BART 0.54 42.0 3.65e-01 87.3% 82.7%
4922608 4033.1.1.1 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.54 45.0 4.12e-01 96.2% 71.4%
3743981 5081.1.1.2 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DER1 0.54 41.0 3.18e-01 83.5% 58.9%
3172664 5001.1.1.87 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › EXS 0.54 42.0 2.87e-01 87.3% 40.6%
3887896 109.3.1.96 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.54 45.0 3.43e-01 92.4% 54.1%
5072106 873.1.1.0 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain 0.54 45.0 3.33e-01 94.9% 91.3%
4851526 609.1.1.1 alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg 0.53 40.0 3.36e-01 83.5% 63.3%
3712092 109.4.1.109 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 0.52 42.0 3.07e-01 89.9% 39.1%
2043418 210.1.2.1 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › Penicil_amidase 0.51 43.0 3.41e-01 94.9% 67.3%
4030059 3903.1.1.0 alpha duplicates or obligate multimers › Reticulocyte binding protein 5 › Reticulocyte binding protein 5 › Reticulocyte binding protein 5 0.51 42.0 2.92e-01 92.4% 97.5%
4989890 601.7.1.3 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 0.50 42.0 3.55e-01 98.7% 95.3%