Back to structures

hypothetical_protein_pv_135

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_135__YP_009001037__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001037 ↗
Protein ID:
hypothetical_protein_pv_135
Kingdom:
euk

Quality

85.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-66_144-223
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kgdA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 41.0 4.60e-01 99.3% 90.4%
3cz8A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 46.0 3.90e-01 88.2% 96.3%
7d88A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 43.0 3.21e-01 79.9% 70.2%
1tzbA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.56 36.0 3.74e-01 100.0% 68.3%
4b9bA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.55 42.0 3.47e-01 81.2% 82.5%
5dclA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 38.0 4.16e-01 99.3% 87.2%
3cg4A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 39.0 4.16e-01 100.0% 84.1%
1kk1A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 50.0 4.52e-01 100.0% 90.3%
4s1hA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.52 47.0 3.77e-01 100.0% 91.6%
4g56A01 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.51 41.0 3.36e-01 87.5% 87.4%
8sp0A01 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.51 41.0 4.01e-01 99.3% 80.5%
5i0fB03 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.51 40.0 3.01e-01 83.3% 63.9%
1bxkA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 46.0 3.83e-01 100.0% 97.6%
5ji5A00 3.40.800.20 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain 0.51 39.0 3.16e-01 83.3% 81.6%
3eucA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 38.0 3.37e-01 78.5% 79.2%
2acvA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.50 45.0 3.67e-01 100.0% 86.8%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3168791 7585.1.1.0 a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins 0.57 44.0 4.45e-01 100.0% 82.1%
5042219 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.55 30.0 3.29e-01 86.8% 62.5%
4489627 2002.1.1.60 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 0.54 40.0 3.25e-01 77.8% 92.5%
1095677 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.54 40.0 4.08e-01 100.0% 81.0%
3273585 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.54 49.0 4.41e-01 99.3% 90.3%
3515117 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.53 49.0 4.28e-01 99.3% 77.1%
428389 7512.1.1.23 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_52 0.53 42.0 4.33e-01 100.0% 90.4%
4976758 2002.1.1.28 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PRAI 0.52 43.0 3.65e-01 87.5% 85.9%
5064421 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.52 47.0 4.61e-01 100.0% 90.0%
5051895 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.52 46.0 4.18e-01 98.6% 98.5%
4180113 2004.1.1.414 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU, MMR_HSR1 0.52 47.0 4.30e-01 100.0% 85.3%
3782285 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.52 46.0 3.73e-01 99.3% 92.3%
4976046 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.52 47.0 4.54e-01 99.3% 91.3%
4076333 2006.1.6.70 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › cpSF2-GREB1 0.51 46.0 4.09e-01 100.0% 74.4%
4312546 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.51 46.0 4.12e-01 99.3% 77.5%
4077790 2005.1.1.13 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.50 45.0 3.97e-01 100.0% 81.4%
4302118 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.50 41.0 3.76e-01 86.8% 76.8%
5056517 2003.1.1.20 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.50 45.0 3.54e-01 100.0% 91.7%
D2 high residues 68-131
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3keyA01 1.10.10.1080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain 0.69 46.0 4.09e-01 89.1% 50.6%
4n06A02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.68 54.0 3.55e-01 85.9% 32.2%
2w4sA00 1.10.10.1440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PHAX RNA-binding domain 0.67 45.0 4.07e-01 87.5% 52.3%
2a2jA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.64 40.0 2.80e-01 95.3% 19.7%
6opmD01 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.63 49.0 3.36e-01 85.9% 35.7%
2gz4A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.60 43.0 3.10e-01 76.6% 90.0%
1cukA03 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.59 32.0 3.64e-01 79.7% 70.8%
2i7aA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.58 46.0 3.46e-01 85.9% 50.3%
2f22A00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.57 48.0 3.79e-01 93.8% 93.0%
1mdyA00 4.10.280.10 Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain 0.57 34.0 3.35e-01 78.1% 55.9%
1mo7A00 3.40.1110.10 Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N 0.57 35.0 2.51e-01 92.2% 18.8%
2wujA00 6.10.250.660 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.56 36.0 3.98e-01 82.8% 84.0%
1a62A01 1.10.720.10 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.55 37.0 4.32e-01 89.1% 97.8%
4xhpA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.55 43.0 3.23e-01 87.5% 45.0%
2bskE00 1.10.287.810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains 0.55 37.0 3.72e-01 85.9% 71.4%
4dkcB00 1.20.1250.80 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-34 0.54 46.0 3.42e-01 93.8% 91.9%
2k7bA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.54 39.0 3.72e-01 78.1% 94.7%
1kf6C00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.54 36.0 2.89e-01 89.1% 33.8%
1wdcC01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.53 41.0 3.91e-01 84.4% 100.0%
2fsjA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.53 45.0 3.58e-01 96.9% 79.0%
3hx4A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.52 44.0 3.17e-01 100.0% 65.9%
3dr6B00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 38.0 2.76e-01 95.3% 28.4%
4az3A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 42.0 2.80e-01 90.6% 23.6%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3736821 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 50.0 3.67e-01 79.7% 78.2%
5032186 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.66 51.0 4.88e-01 84.4% 80.0%
4946343 620.1.1.0 alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases 0.65 51.0 3.90e-01 85.9% 84.7%
3725036 5081.1.1.2 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DER1 0.64 50.0 3.56e-01 87.5% 50.7%
3250585 109.4.1.791 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 0.63 50.0 2.97e-01 90.6% 10.7%
3918784 3289.1.1.11 alpha complex topology › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › WASH-7_mid, WASH-4_N, WASH-7_C 0.60 41.0 2.28e-01 73.4% 12.6%
4954786 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.59 39.0 3.59e-01 89.1% 50.6%
3918118 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.58 42.0 3.32e-01 90.6% 37.0%
3388598 109.4.1.398 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FANCI_S1 0.58 48.0 3.50e-01 92.2% 47.8%
3908207 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 45.0 3.16e-01 89.1% 54.7%
3728141 2003.1.1.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.57 47.0 3.35e-01 93.8% 98.5%
3952698 5069.1.3.2 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Fumarate_red_C 0.56 44.0 3.67e-01 89.1% 70.8%
4067008 3236.2.1.8 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Asp-Al_Ex 0.56 47.0 2.95e-01 96.9% 70.1%
3278278 150.1.1.82 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF6640 0.55 40.0 3.30e-01 76.6% 94.2%
4497855 5069.1.3.2 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Fumarate_red_C 0.55 44.0 3.63e-01 90.6% 66.7%
4149681 101.1.9.0 alpha arrays › HTH › HTH › Putative DNA-binding domain 0.55 42.0 3.47e-01 84.4% 60.8%
3497712 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 44.0 3.09e-01 92.2% 56.4%
4881805 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.54 43.0 4.05e-01 89.1% 74.1%
2707204 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.54 41.0 3.70e-01 84.4% 77.2%
3600769 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.54 39.0 3.82e-01 81.2% 98.7%
3739470 192.2.1.31 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PRA1 0.54 42.0 3.29e-01 96.9% 37.9%
3940349 109.26.1.12 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_Nup160_C, TPR_NUP160_120_M 0.54 45.0 2.83e-01 95.3% 25.2%
3248557 108.1.1.29 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_7 0.54 43.0 3.64e-01 89.1% 72.7%
3787647 192.2.1.31 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PRA1 0.53 40.0 3.59e-01 98.4% 55.0%
3308318 192.2.1.31 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › PRA1 0.53 42.0 3.31e-01 95.3% 41.5%
4939332 604.9.1.0 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 0.53 42.0 3.75e-01 87.5% 58.9%
3882404 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.53 42.0 3.60e-01 89.1% 72.7%
3605428 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.53 43.0 3.04e-01 93.8% 84.0%
5025634 2484.1.1.87 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MreB-like_C 0.53 46.0 3.42e-01 98.4% 83.6%
3947868 2484.1.1.87 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MreB-like_C 0.53 45.0 3.40e-01 98.4% 84.2%
4659161 3289.1.1.11 alpha complex topology › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › WASH-7_mid, WASH-4_N, WASH-7_C 0.53 44.0 2.46e-01 95.3% 21.9%
3387004 3470.1.1.45 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › DUF1440 0.53 39.0 2.91e-01 89.1% 30.9%
5073710 633.6.1.3 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › HpaB 0.52 36.0 2.57e-01 85.9% 22.9%
3602833 2004.1.1.46 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM 0.52 36.0 2.44e-01 75.0% 91.4%
3881579 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 41.0 2.98e-01 90.6% 66.0%
3311288 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 41.0 3.12e-01 87.5% 67.5%
3516571 605.1.1.202 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PhoLip_ATPase_N 0.51 39.0 4.01e-01 85.9% 90.5%
1016743 3255.1.1.1 a/b three-layered sandwiches › a/b domain in flagellar biosynthesis protein flhA › a/b domain in flagellar biosynthesis protein flhA › a/b domain in flagellar biosynthesis protein flhA › FHIPEP 0.51 42.0 3.64e-01 96.9% 82.4%
3179505 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.51 41.0 3.21e-01 93.8% 78.7%
3929433 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.51 38.0 3.22e-01 81.2% 57.3%
3369452 310.2.1.38 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › Hobbit 0.50 39.0 3.55e-01 85.9% 71.1%