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hypothetical_protein_pv_169

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_169__YP_009001071__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001071 ↗
Protein ID:
hypothetical_protein_pv_169
Kingdom:
euk

Quality

73.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (4 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-53_116-132
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2lrrA00 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.83 66.0 6.64e-01 84.3% 85.7%
3hz7A00 3.30.110.40 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain 0.78 68.0 6.70e-01 92.9% 90.4%
2cpmA00 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.78 70.0 6.32e-01 100.0% 88.3%
2fphX01 3.30.1370.160 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.77 66.0 6.46e-01 94.3% 89.6%
3zigA00 3.30.110.150 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › SepF-like protein 0.76 64.0 6.11e-01 91.4% 87.8%
1whrA00 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.75 62.0 5.12e-01 90.0% 50.8%
3pieA02 3.30.1370.250 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.75 62.0 5.52e-01 91.4% 75.0%
3gkuA03 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.74 60.0 6.01e-01 91.4% 97.2%
3douA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.73 60.0 4.48e-01 90.0% 38.9%
5mmjh01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.73 60.0 5.94e-01 90.0% 84.0%
2jc4A00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.73 62.0 4.18e-01 94.3% 36.3%
2yxdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 57.0 4.20e-01 85.7% 41.9%
4fqdB02 3.65.10.10 Alpha Beta › Alpha-beta prism › UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain › Enolpyruvate transferase domain 0.72 55.0 3.94e-01 85.7% 27.3%
2qv6A01 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.69 47.0 3.80e-01 70.0% 76.6%
1akoA00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.68 59.0 4.00e-01 100.0% 54.1%
4i0wA00 3.30.70.2980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 50.0 4.60e-01 81.4% 69.6%
4nxyA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.66 53.0 3.97e-01 88.6% 78.4%
4qc6A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.66 53.0 3.95e-01 88.6% 83.8%
1atgA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.66 53.0 4.47e-01 90.0% 56.6%
1rq8A00 3.30.110.60 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › YhbY-like 0.65 53.0 4.83e-01 91.4% 75.0%
2r7hB00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.64 52.0 4.00e-01 90.0% 85.5%
2reeA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.64 51.0 3.74e-01 90.0% 48.7%
6mfcA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.63 51.0 3.73e-01 90.0% 49.7%
1ucnA00 3.30.70.141 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleoside diphosphate kinase-like domain 0.62 43.0 3.40e-01 72.9% 90.7%
2e9hA01 3.30.30.170 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.61 49.0 4.24e-01 88.6% 55.8%
2hqyA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.61 49.0 4.07e-01 91.4% 84.6%
4durB01 3.50.4.10 Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor 0.60 41.0 3.95e-01 70.0% 65.4%
6vudA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.59 46.0 4.56e-01 90.0% 80.0%
3dfeA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 42.0 3.97e-01 74.3% 68.3%
3afgB01 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.58 47.0 4.45e-01 90.0% 98.9%
4ombA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.58 48.0 3.81e-01 95.7% 66.9%
3zq5A03 3.30.450.270 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PHY domain 0.57 40.0 3.16e-01 74.3% 36.6%
3hrgA01 3.30.420.250 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF3822, N-terminal domain 0.57 39.0 3.11e-01 71.4% 48.3%
4v1al00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.54 43.0 3.57e-01 90.0% 55.6%
4mamA02 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.54 38.0 3.68e-01 75.7% 92.6%
2k5tA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.54 41.0 3.55e-01 90.0% 85.2%
7y6oA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 42.0 3.89e-01 85.7% 71.1%
3mdnD00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.51 41.0 3.08e-01 100.0% 61.4%
ECOD (78)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3198781 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.90 74.0 6.83e-01 85.7% 71.8%
3631911 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.90 77.0 6.38e-01 91.4% 57.4%
3250910 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.89 73.0 7.37e-01 87.1% 90.0%
4012898 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.88 75.0 6.52e-01 90.0% 65.0%
3728094 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.87 74.0 6.46e-01 90.0% 65.0%
4365938 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.86 74.0 6.84e-01 90.0% 74.1%
4012905 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.86 74.0 6.83e-01 90.0% 74.1%
3737985 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.86 73.0 6.38e-01 90.0% 64.0%
3170274 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.86 70.0 6.39e-01 87.1% 68.9%
4317256 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.86 71.0 6.11e-01 88.6% 61.0%
3740807 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.85 71.0 6.66e-01 90.0% 76.5%
3175858 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.84 72.0 6.01e-01 91.4% 57.4%
3190610 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.84 70.0 5.99e-01 90.0% 72.7%
3711102 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.84 69.0 6.08e-01 88.6% 63.0%
3226102 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.84 70.0 5.97e-01 90.0% 66.7%
3637371 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.83 70.0 6.02e-01 90.0% 60.0%
3720966 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.83 69.0 6.23e-01 90.0% 66.3%
3314359 320.1.1.11 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › PF27261 0.83 71.0 6.92e-01 91.4% 86.7%
3403645 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.83 67.0 7.19e-01 88.6% 100.0%
4014318 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.83 69.0 6.45e-01 90.0% 74.1%
3308590 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.83 70.0 6.16e-01 91.4% 69.0%
5080701 2003.1.5.445 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GvpD_bR2 0.83 65.0 4.57e-01 90.0% 28.8%
3185841 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.82 67.0 6.80e-01 88.6% 91.4%
3780948 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.82 75.0 6.63e-01 100.0% 86.0%
4608678 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.82 70.0 6.69e-01 91.4% 81.2%
3578925 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.82 68.0 5.92e-01 90.0% 67.6%
3596513 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.82 69.0 6.26e-01 90.0% 73.3%
3262749 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.82 68.0 5.91e-01 90.0% 68.6%
3581967 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.82 68.0 7.09e-01 91.4% 100.0%
3237732 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.81 69.0 5.77e-01 91.4% 56.5%
3595328 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.81 67.0 5.75e-01 88.6% 60.0%
3174787 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.81 68.0 6.13e-01 91.4% 68.4%
3879109 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.80 66.0 5.74e-01 88.6% 61.5%
3321720 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.80 66.0 5.66e-01 90.0% 62.7%
4361828 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.79 66.0 5.72e-01 90.0% 61.9%
3926462 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.79 66.0 5.69e-01 90.0% 61.9%
3455192 320.1.1.11 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › PF27261 0.78 72.0 7.02e-01 100.0% 93.3%
4989805 328.5.1.0 ↗ a+b two layers › IF3-like › SirA-like › SirA-like 0.78 64.0 6.41e-01 88.6% 90.0%
4228350 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.77 64.0 6.58e-01 90.0% 100.0%
4981701 328.5.1.1 ↗ a+b two layers › IF3-like › SirA-like › SirA-like › TusA 0.77 61.0 6.34e-01 87.1% 92.3%
3357930 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.76 62.0 6.10e-01 88.6% 85.3%
3218484 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.76 62.0 6.28e-01 88.6% 91.4%
3260870 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.75 60.0 5.55e-01 88.6% 67.8%
3609147 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.75 62.0 5.43e-01 90.0% 61.9%
5617 320.1.1.1 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.75 62.0 5.12e-01 90.0% 50.8%
4973677 2003.1.5.42 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_21 0.75 61.0 4.16e-01 88.6% 39.3%
3710687 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.75 58.0 5.71e-01 84.3% 81.3%
4011288 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.75 60.0 6.44e-01 85.7% 100.0%
4105291 320.2.1.1 ↗ a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain › Ribosomal_S8 0.75 58.0 6.01e-01 84.3% 93.8%
5011403 2003.1.5.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F 0.74 60.0 3.87e-01 90.0% 30.2%
5001543 2003.1.5.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F 0.74 60.0 3.90e-01 90.0% 28.5%
3561915 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.73 60.0 5.86e-01 90.0% 89.3%
3960456 246.3.1.0 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like 0.72 62.0 4.18e-01 95.7% 55.4%
3175131 246.3.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.71 63.0 3.94e-01 100.0% 30.7%
4029853 2003.1.5.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F 0.71 56.0 3.49e-01 90.0% 25.5%
3955112 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.70 55.0 5.02e-01 84.3% 64.4%
5023789 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.70 53.0 4.97e-01 80.0% 68.2%
3599880 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.69 61.0 4.02e-01 100.0% 30.5%
5009377 2003.1.5.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F 0.68 54.0 3.68e-01 90.0% 28.0%
3660054 390.1.1.0 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.67 46.0 4.21e-01 71.4% 56.8%
3502122 390.1.1.1 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 0.67 46.0 4.25e-01 71.4% 62.2%
4933792 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.67 53.0 5.07e-01 84.3% 85.0%
3451493 390.1.1.6 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_2 0.67 46.0 4.16e-01 71.4% 56.8%
3352812 390.1.1.1 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 0.67 45.0 4.33e-01 70.0% 67.5%
3781988 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.66 43.0 4.01e-01 74.3% 52.8%
5022251 2003.1.5.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F 0.66 47.0 3.09e-01 77.1% 22.6%
4943384 2003.1.5.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F 0.65 47.0 3.13e-01 77.1% 24.4%
4938255 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.64 49.0 4.72e-01 81.4% 73.8%
3959690 304.11.1.0 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.63 41.0 3.84e-01 74.3% 54.1%
4978366 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.63 51.0 5.11e-01 85.7% 100.0%
4479273 242.1.1.1 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.62 47.0 3.88e-01 82.9% 53.1%
5054189 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.61 43.0 4.52e-01 78.6% 86.7%
3190806 390.1.1.1 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 0.60 41.0 4.10e-01 70.0% 68.9%
4821456 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.60 51.0 5.26e-01 92.9% 97.0%
5015890 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.58 43.0 4.02e-01 84.3% 62.2%
4995013 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.58 46.0 4.35e-01 85.7% 95.2%
3667166 304.20.1.2 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › Nrap_D3 0.57 41.0 3.22e-01 78.6% 56.4%
3598758 304.20.1.0 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.57 42.0 3.25e-01 78.6% 48.5%
D2 high residues 55-114
PDB