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hypothetical_protein_pv_16

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_16__YP_009000918__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009000918 ↗
Protein ID:
hypothetical_protein_pv_16
Kingdom:
euk

Quality

74.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 64-137
PDB
Domain cluster: representative
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.80 58.0 4.87e-01 75.7% 96.6%
3udcA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 57.0 4.83e-01 75.7% 49.6%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.79 58.0 4.67e-01 77.0% 77.4%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.76 55.0 5.53e-01 77.0% 75.7%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.75 55.0 4.35e-01 77.0% 46.3%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 53.0 3.62e-01 83.8% 22.9%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.75 65.0 5.83e-01 94.6% 91.2%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.75 56.0 4.54e-01 78.4% 43.6%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.74 54.0 5.15e-01 77.0% 65.5%
2oauA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 54.0 4.79e-01 75.7% 54.9%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.73 53.0 4.72e-01 90.5% 54.9%
1o3uA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.72 53.0 4.45e-01 77.0% 98.3%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.72 55.0 4.20e-01 81.1% 95.1%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 53.0 3.53e-01 86.5% 21.4%
3itfA00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.71 50.0 4.37e-01 83.8% 49.5%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.71 51.0 4.65e-01 78.4% 57.0%
4cc9B00 1.20.5.4730 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 46.0 4.13e-01 70.3% 51.0%
1urvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.69 58.0 4.60e-01 93.2% 100.0%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 44.0 4.38e-01 91.9% 62.8%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 59.0 5.30e-01 94.6% 88.1%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 57.0 5.09e-01 94.6% 86.0%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.67 47.0 4.42e-01 85.1% 60.0%
3ecsC01 1.20.120.1070 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain 0.66 49.0 4.48e-01 79.7% 61.0%
2ynqB00 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.66 50.0 3.97e-01 87.8% 39.7%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.66 52.0 5.19e-01 85.1% 83.1%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 57.0 3.91e-01 100.0% 54.1%
6wk3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 56.0 4.55e-01 100.0% 97.9%
1txdA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.64 58.0 4.03e-01 98.6% 50.6%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.64 51.0 4.32e-01 86.5% 52.9%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.63 57.0 4.36e-01 98.6% 69.9%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.63 45.0 4.39e-01 77.0% 68.3%
3tjmA02 1.10.1470.20 Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › Fatty acid synthase; domain 2 0.63 47.0 4.44e-01 81.1% 100.0%
1mhyG01 1.20.1280.10 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 1 0.62 45.0 4.71e-01 89.2% 83.8%
2vqgA00 1.10.10.1280 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Alpha-helical porin B/porin C 0.62 46.0 4.64e-01 79.7% 81.6%
1nklA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.62 49.0 4.85e-01 90.5% 82.1%
3rcyB01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.61 52.0 4.17e-01 93.2% 61.0%
2h21A02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.60 55.0 4.18e-01 100.0% 92.1%
5ojcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 51.0 4.09e-01 97.3% 97.4%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.60 47.0 4.55e-01 98.6% 75.0%
1oj6A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 51.0 4.14e-01 98.6% 100.0%
3frqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 47.0 3.57e-01 90.5% 40.8%
1aa7A02 1.10.10.180 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Influenza matrix protein M1, N-terminal subdomain 2 0.58 42.0 4.13e-01 91.9% 71.8%
2of7A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 48.0 4.05e-01 97.3% 66.4%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.58 42.0 4.28e-01 90.5% 79.5%
3o39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 42.0 3.91e-01 81.1% 62.5%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 46.0 4.57e-01 98.6% 86.8%
1chuA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.53 43.0 4.15e-01 90.5% 79.5%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.53 37.0 3.92e-01 77.0% 83.6%
2mgqA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.52 40.0 4.10e-01 100.0% 92.6%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3258488 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 60.0 5.34e-01 75.7% 88.0%
3185618 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.81 74.0 4.53e-01 100.0% 62.2%
3224304 4120.1.1.30 few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › DUF842 0.79 56.0 5.36e-01 74.3% 68.2%
4970333 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.77 56.0 5.10e-01 75.7% 62.1%
5010451 186.1.1.4 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_4 0.77 66.0 5.73e-01 93.2% 69.1%
4998688 192.2.1.89 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › DUF7121 0.77 57.0 3.84e-01 91.9% 23.3%
5040210 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.74 51.0 4.72e-01 73.0% 56.8%
3952510 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.73 54.0 5.41e-01 77.0% 76.0%
3954313 150.5.1.52 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE 0.73 54.0 4.91e-01 77.0% 86.3%
4441061 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.73 49.0 4.54e-01 70.3% 73.7%
4025636 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 54.0 4.19e-01 81.1% 65.2%
3952753 150.7.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PE › PE › PE 0.71 49.0 4.92e-01 71.6% 74.7%
3272165 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.70 50.0 4.36e-01 74.3% 55.5%
3640760 3291.1.1.17 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF202 0.70 52.0 4.55e-01 78.4% 58.2%
4174467 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.69 53.0 5.02e-01 82.4% 93.3%
3712299 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.69 50.0 3.54e-01 75.7% 47.4%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.68 53.0 5.07e-01 87.8% 71.8%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 53.0 5.07e-01 87.8% 71.8%
3567382 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 59.0 5.03e-01 93.2% 89.6%
4106453 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.68 52.0 4.60e-01 81.1% 61.9%
3234270 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.67 60.0 5.68e-01 95.9% 84.7%
5045348 604.34.1.0 alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase 0.66 55.0 5.31e-01 94.6% 80.0%
4014217 102.5.1.0 alpha arrays › HhH/H2TH › SAM-like subdomain in Sec63-like proteins › SAM-like subdomain in Sec63-like proteins 0.66 58.0 5.42e-01 94.6% 91.0%
3591629 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.66 47.0 4.14e-01 77.0% 54.8%
3977695 3711.1.1.1 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ 0.66 49.0 4.11e-01 78.4% 48.3%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.65 53.0 5.10e-01 86.5% 75.3%
3988260 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.64 49.0 3.17e-01 81.1% 18.5%
3845930 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.64 58.0 4.67e-01 100.0% 84.3%
3989031 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.64 55.0 3.81e-01 95.9% 47.6%
3681353 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.63 53.0 5.09e-01 97.3% 80.0%
3829016 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.63 57.0 4.78e-01 100.0% 85.6%
3724761 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.63 51.0 5.22e-01 87.8% 90.0%
5042276 4163.1.2.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF2 C-terminal domain-like › Sld5 0.62 54.0 4.82e-01 94.6% 83.5%
4357993 3291.1.1.58 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › QcrA_N 0.60 46.0 3.91e-01 82.4% 50.8%
5002309 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.60 48.0 3.69e-01 89.2% 49.1%
3737926 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.60 54.0 4.01e-01 98.6% 53.9%
3782133 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.60 52.0 3.68e-01 94.6% 53.5%
3321357 609.1.1.1 alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg 0.60 44.0 4.02e-01 78.4% 81.0%
3382744 109.38.1.2 alpha superhelices › Repetitive alpha hairpins › Telomere length regulation protein TEL2 › Telomere length regulation protein TEL2 › Telomere_reg-2, TELO2_ARM 0.59 51.0 2.99e-01 97.3% 17.5%
3204938 101.1.1.228 alpha arrays › HTH › HTH › Three-helical HTH › Eaf7 0.59 51.0 4.78e-01 95.9% 97.8%
3453526 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.59 50.0 4.22e-01 94.6% 58.4%
5046461 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.59 51.0 3.72e-01 95.9% 54.5%
4089654 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.58 53.0 4.69e-01 100.0% 80.0%
1504794 186.1.1.0 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.58 45.0 3.98e-01 87.8% 66.7%
3688063 101.1.1.148 alpha arrays › HTH › HTH › Three-helical HTH › EPL1 0.58 47.0 4.27e-01 91.9% 86.7%
4025520 108.1.1.30 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_8 0.55 37.0 3.62e-01 70.3% 72.9%
3943870 3711.1.1.1 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ 0.55 42.0 3.75e-01 81.1% 84.8%
5039732 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 49.0 4.24e-01 98.6% 92.0%
3750022 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.54 46.0 4.08e-01 97.3% 85.5%
3215052 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.54 36.0 3.55e-01 71.6% 72.9%
3303852 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.53 43.0 4.16e-01 89.2% 82.4%
3789467 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.53 44.0 4.01e-01 87.8% 70.5%
3935027 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 42.0 3.92e-01 95.9% 90.0%
3952920 3625.1.1.1 alpha bundles › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain › Cmr2_hel_dom2 0.50 41.0 3.96e-01 94.6% 85.9%
3699646 610.1.1.1 alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like › ERp29 0.50 37.0 3.52e-01 82.4% 98.9%