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hypothetical_protein_pv_172
Euk-VirPithovirus_sibericum
hypothetical_protein_pv_172__YP_009001074__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001074 ↗
- Protein ID:
- hypothetical_protein_pv_172
- Kingdom:
- euk
Quality
71.9
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 19-50_114-141
Domain cluster:
rep: hypothetical_protein_pv_173__YP_009001075__Pithovirus_sibericum__1450746__D22-53_113-126
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1q7sA00 | 3.40.1490.10 | Alpha Beta › 3-Layer(aba) Sandwich › Bit1 › Bit1 | 0.78 | 52.0 | 4.17e-01 | 70.0% | 83.8% |
| 3gkuA03 | 3.30.1370.50 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain | 0.73 | 50.0 | 4.78e-01 | 71.7% | 62.0% |
| 2yxlA03 | 3.30.70.1170 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sun protein; domain 3 | 0.72 | 48.0 | 4.96e-01 | 70.0% | 72.4% |
| 1yj7B01 | 3.30.70.1530 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 | 0.69 | 47.0 | 4.48e-01 | 70.0% | 60.6% |
| 2iruA02 | 3.30.70.3300 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 62.0 | 4.68e-01 | 100.0% | 89.9% |
| 2djwA01 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.68 | 45.0 | 4.22e-01 | 70.0% | 55.4% |
| 1q5yC00 | 3.30.70.1150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 | 0.68 | 45.0 | 4.14e-01 | 70.0% | 58.5% |
| 1u8sA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.66 | 47.0 | 4.23e-01 | 76.7% | 94.2% |
| 6lxgA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.66 | 44.0 | 4.21e-01 | 70.0% | 64.4% |
| 4i0wA00 | 3.30.70.2980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 50.0 | 4.32e-01 | 83.3% | 60.9% |
| 1sqgA03 | 3.30.70.1170 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sun protein; domain 3 | 0.64 | 43.0 | 4.42e-01 | 70.0% | 72.4% |
| 3mtjA03 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.64 | 44.0 | 4.12e-01 | 71.7% | 59.2% |
| 2xf1A00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.63 | 49.0 | 4.01e-01 | 88.3% | 49.2% |
| 1mkmA03 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.62 | 49.0 | 3.71e-01 | 93.3% | 92.4% |
| 5x6vG00 | 3.30.450.190 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.62 | 50.0 | 3.97e-01 | 91.7% | 81.1% |
| 7bjkA02 | 3.55.40.20 | Alpha Beta › 3-Layer(bab) Sandwich › minor pseudopilin epsh fold › Iron/manganese superoxide dismutase, C-terminal domain | 0.62 | 49.0 | 4.09e-01 | 91.7% | 50.4% |
| 1x4dA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.61 | 44.0 | 3.81e-01 | 78.3% | 77.5% |
| 1xreA02 | 3.55.40.20 | Alpha Beta › 3-Layer(bab) Sandwich › minor pseudopilin epsh fold › Iron/manganese superoxide dismutase, C-terminal domain | 0.61 | 48.0 | 3.99e-01 | 90.0% | 49.1% |
| 1i6uA01 | 3.30.1370.30 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › | 0.61 | 40.0 | 3.95e-01 | 70.0% | 64.7% |
| 1svdM00 | 3.30.190.10 | Alpha Beta › 2-Layer Sandwich › Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase › Ribulose bisphosphate carboxylase, small subunit | 0.60 | 45.0 | 3.76e-01 | 100.0% | 45.4% |
| 2l72A00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.60 | 46.0 | 3.85e-01 | 88.3% | 48.3% |
| 1skoB00 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.60 | 47.0 | 3.88e-01 | 90.0% | 81.9% |
| 1gmnA01 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.59 | 52.0 | 4.60e-01 | 100.0% | 68.2% |
| 2crlA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 45.0 | 4.30e-01 | 83.3% | 91.3% |
| 1kw3B02 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.58 | 47.0 | 3.63e-01 | 95.0% | 89.0% |
| 5xamA02 | 3.30.70.3220 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 44.0 | 3.24e-01 | 83.3% | 48.4% |
| 2lxxA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.58 | 46.0 | 3.68e-01 | 100.0% | 66.4% |
| 4durB01 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.57 | 46.0 | 4.31e-01 | 100.0% | 71.6% |
| 1qm9A01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.57 | 47.0 | 4.14e-01 | 100.0% | 92.9% |
| 3ms6A00 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.56 | 38.0 | 3.38e-01 | 71.7% | 82.2% |
| 2jheA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.56 | 47.0 | 4.29e-01 | 96.7% | 93.8% |
| 1wg1A01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.55 | 41.0 | 3.98e-01 | 83.3% | 98.6% |
| 3p0jA03 | 1.10.240.10 | Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase | 0.55 | 34.0 | 2.98e-01 | 93.3% | 40.0% |
| 1jelP00 | 3.30.1340.10 | Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › HPr-like | 0.54 | 36.0 | 3.33e-01 | 70.0% | 76.5% |
| 4i68A00 | 3.30.70.1800 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 44.0 | 3.99e-01 | 100.0% | 75.6% |
| 2rftA02 | 3.90.209.20 | Alpha Beta › Alpha-Beta Complex › Hemagglutinin (Ha1 Chain); Chain: A; domain 1 › Haemagglutinin, alpha/beta domain, HA1 chain | 0.52 | 40.0 | 2.80e-01 | 91.7% | 72.8% |
| 1l1lA03 | 3.90.1390.10 | Alpha Beta › Alpha-Beta Complex › b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 › b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 | 0.51 | 39.0 | 3.48e-01 | 86.7% | 57.4% |
| 4e6xB00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.50 | 39.0 | 2.64e-01 | 91.7% | 95.3% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3631911 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.85 | 59.0 | 4.62e-01 | 71.7% | 37.4% |
| 3198781 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.85 | 58.0 | 5.04e-01 | 70.0% | 49.4% |
| 3190610 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.84 | 58.0 | 4.63e-01 | 71.7% | 39.1% |
| 4012905 | 320.1.1.0 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain | 0.83 | 57.0 | 5.04e-01 | 71.7% | 50.6% |
| 4365938 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.83 | 57.0 | 5.02e-01 | 71.7% | 50.6% |
| 4977576 | 219.1.1.153 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › BtrH_N | 0.78 | 52.0 | 3.55e-01 | 70.0% | 50.2% |
| 4821456 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.77 | 53.0 | 5.10e-01 | 73.3% | 64.2% |
| 4976823 | 305.2.1.0 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) | 0.75 | 50.0 | 4.66e-01 | 70.0% | 56.0% |
| 4654074 | 304.5.1.0 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like | 0.74 | 53.0 | 4.56e-01 | 75.0% | 78.9% |
| 3528332 | 304.163.1.1 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › R1_ABCA1 | 0.74 | 49.0 | 4.59e-01 | 70.0% | 56.0% |
| 3597641 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.73 | 50.0 | 4.66e-01 | 71.7% | 58.7% |
| 3814789 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.70 | 47.0 | 4.64e-01 | 70.0% | 72.3% |
| 3164326 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.70 | 48.0 | 4.51e-01 | 71.7% | 64.4% |
| 3966114 | 320.1.1.0 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain | 0.69 | 54.0 | 4.94e-01 | 90.0% | 68.2% |
| 4945662 | 320.2.1.1 ↗ | a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain › Ribosomal_S8 | 0.69 | 46.0 | 4.57e-01 | 70.0% | 66.2% |
| 4341023 | 320.2.1.1 ↗ | a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain › Ribosomal_S8 | 0.69 | 46.0 | 4.54e-01 | 70.0% | 66.2% |
| 4977666 | 305.1.1.1 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L | 0.67 | 45.0 | 3.98e-01 | 70.0% | 50.0% |
| 4968895 | 5103.1.1.2 ↗ | a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › DUF1015 | 0.67 | 57.0 | 4.30e-01 | 100.0% | 66.7% |
| 4973504 | 2003.1.5.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ | 0.67 | 45.0 | 3.26e-01 | 70.0% | 27.3% |
| 3813809 | 304.8.1.45 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant | 0.67 | 45.0 | 3.82e-01 | 70.0% | 46.0% |
| 5075438 | 304.4.1.29 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 | 0.66 | 47.0 | 4.20e-01 | 75.0% | 88.2% |
| 2141585 | 304.137.1.3 ↗ | a+b two layers › Alpha-beta plaits › NOL1/NOP2/sun N-terminal ferredoxin-like domain › NOL1/NOP2/sun N-terminal ferredoxin-like domain › RsmF-B_ferredox | 0.66 | 44.0 | 3.71e-01 | 70.0% | 41.3% |
| 5077217 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.64 | 42.0 | 3.98e-01 | 70.0% | 54.7% |
| 3626962 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.63 | 53.0 | 3.61e-01 | 95.0% | 76.0% |
| 4212253 | 304.150.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA | 0.62 | 54.0 | 4.71e-01 | 100.0% | 87.1% |
| 3786894 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.62 | 48.0 | 4.35e-01 | 83.3% | 96.2% |
| 4217761 | 304.14.1.1 ↗ | a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR | 0.61 | 47.0 | 4.29e-01 | 83.3% | 86.1% |
| 3803779 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.61 | 48.0 | 4.49e-01 | 86.7% | 82.7% |
| 5066757 | 304.128.1.1 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB › FtsX | 0.61 | 40.0 | 2.80e-01 | 70.0% | 19.5% |
| 3407050 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.60 | 50.0 | 4.59e-01 | 100.0% | 77.6% |
| 3596732 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.59 | 48.0 | 4.54e-01 | 100.0% | 74.7% |
| 5050494 | 223.2.1.5 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7 | 0.59 | 48.0 | 3.85e-01 | 93.3% | 73.8% |
| 4977323 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.59 | 48.0 | 3.85e-01 | 93.3% | 80.8% |
| 3735504 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.58 | 48.0 | 4.28e-01 | 100.0% | 67.4% |
| 3515912 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.58 | 48.0 | 4.36e-01 | 100.0% | 75.6% |
| 3930134 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.58 | 49.0 | 4.34e-01 | 100.0% | 71.6% |
| 3936711 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.58 | 47.0 | 4.51e-01 | 100.0% | 78.7% |
| 4006107 | 304.8.1.2 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT | 0.58 | 48.0 | 4.47e-01 | 93.3% | 100.0% |
| 3239582 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.57 | 50.0 | 4.21e-01 | 100.0% | 76.2% |
| 3216877 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.57 | 49.0 | 4.44e-01 | 100.0% | 74.1% |
| 3585693 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.57 | 48.0 | 4.26e-01 | 100.0% | 73.7% |
| 3925529 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.57 | 47.0 | 4.42e-01 | 100.0% | 77.5% |
| 3214943 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.57 | 47.0 | 4.42e-01 | 100.0% | 80.0% |
| 3942221 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.57 | 48.0 | 4.48e-01 | 95.0% | 100.0% |
| 3390334 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.57 | 48.0 | 4.40e-01 | 100.0% | 74.1% |
| 141273 | 223.2.1.16 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › LAMTOR5 | 0.56 | 38.0 | 3.37e-01 | 71.7% | 81.3% |
| 4979481 | 304.110.1.0 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like | 0.56 | 48.0 | 4.23e-01 | 98.3% | 97.8% |
| 3625214 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.55 | 45.0 | 4.01e-01 | 100.0% | 61.1% |
| 4590927 | 304.28.1.2 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG | 0.55 | 43.0 | 3.77e-01 | 86.7% | 85.6% |
| 5047768 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.54 | 41.0 | 3.33e-01 | 90.0% | 79.7% |
| 1281177 | 304.9.1.35 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Hera_RBD | 0.53 | 44.0 | 3.99e-01 | 100.0% | 75.6% |
| 3676447 | 387.1.5.0 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like | 0.53 | 35.0 | 3.72e-01 | 70.0% | 94.0% |
| 4946747 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.52 | 38.0 | 3.46e-01 | 83.3% | 78.9% |
| 4619946 | 223.2.1.16 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › LAMTOR5 | 0.52 | 40.0 | 3.60e-01 | 88.3% | 94.4% |
| 3691594 | 1.1.5.36 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyrid_ox_like | 0.51 | 37.0 | 2.68e-01 | 76.7% | 68.1% |
| 3947018 | 223.1.1.43 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › CusS | 0.51 | 42.0 | 3.07e-01 | 100.0% | 60.0% |
D2
high
residues 52-111