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hypothetical_protein_pv_216
Euk-VirPithovirus_sibericum
hypothetical_protein_pv_216__YP_009001118__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001118 ↗
- Protein ID:
- hypothetical_protein_pv_216
- Kingdom:
- euk
Quality
76.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 120-200
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4qfvC02 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.65 | 46.0 | 4.99e-01 | 79.0% | 92.3% |
| 3ezxA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.64 | 46.0 | 4.60e-01 | 76.5% | 83.7% |
| 3b7bB00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.60 | 50.0 | 3.61e-01 | 90.1% | 44.6% |
| 2g1pA02 | 1.10.1020.10 | Mainly Alpha › Orthogonal Bundle › Adenine-specific Methyltransferase; domain 2 › Adenine-specific Methyltransferase, Domain 2 | 0.58 | 41.0 | 3.92e-01 | 76.5% | 63.0% |
| 3pubA01 | 1.10.10.2400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain | 0.58 | 45.0 | 4.68e-01 | 90.1% | 93.2% |
| 4evfA01 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.57 | 41.0 | 4.32e-01 | 75.3% | 100.0% |
| 5eidA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.56 | 50.0 | 4.39e-01 | 100.0% | 80.5% |
| 2icwG02 | 1.10.10.530 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › mam-mhc complex, Chain D, Domain 2 | 0.53 | 36.0 | 3.57e-01 | 70.4% | 79.8% |
D2
medium
residues 44-118
Domain cluster:
rep: hypothetical_protein_pv_222__YP_009001124__Pithovirus_sibericum__1450746__D60-113
D3
medium
residues 207-297
Domain cluster:
rep: hypothetical_protein_pv_222__YP_009001124__Pithovirus_sibericum__1450746__D227-299
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1gwcA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.69 | 47.0 | 4.10e-01 | 70.3% | 75.2% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.66 | 45.0 | 3.75e-01 | 70.3% | 89.6% |
| 2pftA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.65 | 56.0 | 3.54e-01 | 98.9% | 45.9% |
| 2nr4A02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.64 | 40.0 | 4.88e-01 | 84.6% | 100.0% |
| 2b6cA01 | 1.20.1660.10 | Mainly Alpha › Up-down Bundle › ARM repeat fold › Hypothetical protein (EF3068) | 0.63 | 52.0 | 4.85e-01 | 92.3% | 97.4% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 43.0 | 4.02e-01 | 70.3% | 89.3% |
| 4a64A02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.62 | 45.0 | 4.19e-01 | 76.9% | 90.6% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 40.0 | 3.60e-01 | 90.1% | 46.6% |
| 1wy6A00 | 1.25.40.350 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 53.0 | 4.50e-01 | 100.0% | 79.2% |
| 3ma5A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 48.0 | 4.90e-01 | 91.2% | 97.8% |
| 4bwrA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 49.0 | 3.19e-01 | 96.7% | 20.1% |
| 6ktqA01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.57 | 49.0 | 3.45e-01 | 94.5% | 37.4% |
| 7bobA01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.56 | 46.0 | 3.20e-01 | 94.5% | 43.4% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.56 | 49.0 | 4.22e-01 | 100.0% | 96.7% |
| 2qtqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 44.0 | 3.49e-01 | 86.8% | 80.2% |
| 3bniB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 37.0 | 3.13e-01 | 70.3% | 83.6% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.54 | 39.0 | 3.53e-01 | 90.1% | 53.9% |
| 4ap2B01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.54 | 42.0 | 3.83e-01 | 87.9% | 88.1% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 37.0 | 3.01e-01 | 72.5% | 77.2% |
| 1xrtA02 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.54 | 46.0 | 3.44e-01 | 100.0% | 61.9% |
| 1ldjA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.53 | 42.0 | 3.88e-01 | 89.0% | 95.9% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 45.0 | 3.96e-01 | 100.0% | 92.9% |
| 3mczA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.51 | 42.0 | 3.16e-01 | 94.5% | 43.1% |
| 2ddhA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.51 | 38.0 | 3.47e-01 | 95.6% | 61.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 41.0 | 3.28e-01 | 86.8% | 70.5% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3725739 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.70 | 61.0 | 4.55e-01 | 95.6% | 41.8% |
| 3503794 | 109.4.1.1340 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_m, COG4_C, COG4_N | 0.68 | 55.0 | 3.27e-01 | 87.9% | 34.7% |
| 3210941 | 109.4.1.371 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RTP1_C1 | 0.68 | 60.0 | 3.95e-01 | 100.0% | 36.9% |
| 3211010 | 109.4.1.158 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C | 0.68 | 60.0 | 4.08e-01 | 98.9% | 37.9% |
| 4015517 | 226.1.1.1 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain › BTB | 0.65 | 59.0 | 4.45e-01 | 100.0% | 94.4% |
| 3665902 | 109.27.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain | 0.65 | 57.0 | 5.23e-01 | 97.8% | 96.7% |
| 3299036 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.64 | 55.0 | 5.38e-01 | 100.0% | 88.0% |
| 3205307 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.64 | 58.0 | 4.48e-01 | 100.0% | 94.9% |
| 3379149 | 109.4.1.1256 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 | 0.64 | 56.0 | 5.51e-01 | 100.0% | 92.0% |
| 3675450 | 109.4.1.621 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_3 | 0.63 | 54.0 | 4.47e-01 | 100.0% | 56.6% |
| 3353463 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.62 | 54.0 | 4.54e-01 | 100.0% | 55.8% |
| 4023909 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 55.0 | 3.68e-01 | 100.0% | 41.3% |
| 3678435 | 109.3.1.36 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › GCFC | 0.62 | 53.0 | 3.59e-01 | 97.8% | 69.4% |
| 4634 | 109.9.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Hypothetical protein ST1625 › Hypothetical protein ST1625 › DUF1955 | 0.61 | 53.0 | 4.50e-01 | 100.0% | 79.2% |
| 3677985 | 109.4.1.1258 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 | 0.60 | 52.0 | 4.30e-01 | 100.0% | 77.6% |
| 3578314 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.58 | 51.0 | 4.34e-01 | 98.9% | 58.1% |
| 3822893 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.56 | 47.0 | 4.08e-01 | 96.7% | 62.0% |
| 3596878 | 109.40.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain | 0.54 | 47.0 | 4.23e-01 | 97.8% | 75.4% |
D4
medium
residues 298-388
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2zgdA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.52 | 44.0 | 4.35e-01 | 100.0% | 88.7% |
| 6u8yL01 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.52 | 40.0 | 2.72e-01 | 84.6% | 69.5% |
| 1owlA02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 39.0 | 3.54e-01 | 81.3% | 70.7% |
| 2vqrA01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.50 | 38.0 | 2.51e-01 | 84.6% | 67.1% |
| 6jd6B00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.50 | 44.0 | 3.51e-01 | 100.0% | 59.9% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4013140 | 109.3.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank | 0.52 | 40.0 | 3.63e-01 | 96.7% | 59.2% |
| 3930576 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.52 | 38.0 | 4.01e-01 | 91.2% | 90.0% |
| 3749173 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.52 | 43.0 | 4.07e-01 | 100.0% | 77.3% |
| 3475979 | 109.3.1.96 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 | 0.50 | 44.0 | 3.42e-01 | 100.0% | 56.2% |
D5
medium
residues 389-493