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hypothetical_protein_pv_237
Euk-VirPithovirus_sibericum
hypothetical_protein_pv_237__YP_009001139__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001139 ↗
- Protein ID:
- hypothetical_protein_pv_237
- Kingdom:
- euk
Quality
70.9
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-224
Domain cluster:
rep: conserved_putative_membrane_protein__YP_009094801__Melbournevirus__1560514__D5-197
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19069.7 best | DUF5765 | 196.9 | 5.40e-58 | 99.1% | 96.5% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.67 | 28.0 | 3.77e-01 | 97.3% | 71.1% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 60.0 | 5.61e-01 | 100.0% | 91.6% |
| 8hixR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 58.0 | 5.39e-01 | 98.6% | 92.2% |
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 54.0 | 5.71e-01 | 98.6% | 99.0% |
| 5unhA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 59.0 | 5.47e-01 | 100.0% | 95.3% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 56.0 | 5.72e-01 | 100.0% | 96.8% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.63 | 36.0 | 4.50e-01 | 90.9% | 89.8% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 57.0 | 5.75e-01 | 100.0% | 97.3% |
| 7wujE01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 56.0 | 5.32e-01 | 98.6% | 88.9% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 56.0 | 5.22e-01 | 100.0% | 95.0% |
| 7rkxR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 56.0 | 5.31e-01 | 100.0% | 95.5% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 55.0 | 5.55e-01 | 100.0% | 96.8% |
| 4mbsA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 56.0 | 4.83e-01 | 100.0% | 92.8% |
| 8anqA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 56.0 | 5.64e-01 | 100.0% | 98.2% |
| 4l6rA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 56.0 | 5.11e-01 | 100.0% | 85.3% |
| 6gpxB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 55.0 | 5.17e-01 | 97.7% | 94.7% |
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 55.0 | 5.53e-01 | 100.0% | 97.3% |
| 6gyhA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 55.0 | 5.45e-01 | 98.2% | 94.7% |
| 1at9A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 55.0 | 5.47e-01 | 100.0% | 96.1% |
| 6ko5A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 54.0 | 4.92e-01 | 99.5% | 95.2% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.59 | 36.0 | 4.23e-01 | 90.0% | 85.1% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 40.0 | 4.34e-01 | 99.1% | 83.3% |
| 7kfuC02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.54 | 41.0 | 4.02e-01 | 80.5% | 72.5% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.54 | 40.0 | 4.24e-01 | 95.5% | 85.9% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.53 | 38.0 | 3.81e-01 | 72.3% | 81.7% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.52 | 33.0 | 4.04e-01 | 74.5% | 100.0% |
| 6a7hA01 | 1.20.140.180 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.51 | 27.0 | 3.49e-01 | 92.3% | 85.6% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3213842 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.68 | 63.0 | 5.77e-01 | 98.6% | 90.9% |
| 5019573 | 5001.1.1.292 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HisKA_7TM | 0.67 | 61.0 | 6.09e-01 | 99.5% | 99.6% |
| 4947496 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.66 | 60.0 | 6.04e-01 | 100.0% | 94.2% |
| 4010993 | 5001.1.1.125 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF7703 | 0.66 | 62.0 | 5.92e-01 | 100.0% | 97.3% |
| 3271008 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.66 | 60.0 | 5.98e-01 | 100.0% | 93.0% |
| 5013396 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.66 | 55.0 | 5.75e-01 | 100.0% | 96.0% |
| 5002084 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.66 | 61.0 | 5.93e-01 | 100.0% | 93.9% |
| 4601701 | 5001.1.1.22 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › STE3 | 0.65 | 60.0 | 5.32e-01 | 98.2% | 91.3% |
| 4014428 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.65 | 61.0 | 5.59e-01 | 100.0% | 92.9% |
| 5014284 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.65 | 54.0 | 5.69e-01 | 99.1% | 97.5% |
| 3239305 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 60.0 | 5.35e-01 | 100.0% | 91.8% |
| 3179175 | 5001.1.1.22 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › STE3 | 0.64 | 59.0 | 5.05e-01 | 98.2% | 86.2% |
| 3894309 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 59.0 | 5.44e-01 | 98.6% | 85.4% |
| 3906091 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 59.0 | 5.22e-01 | 98.6% | 84.8% |
| 3539560 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.64 | 59.0 | 5.39e-01 | 98.6% | 86.4% |
| 3877645 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.64 | 58.0 | 5.28e-01 | 98.6% | 87.2% |
| 3790952 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.63 | 35.0 | 4.24e-01 | 89.5% | 80.7% |
| 4629509 | 5001.1.1.22 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › STE3 | 0.63 | 58.0 | 5.21e-01 | 100.0% | 99.7% |
| 3540024 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.63 | 58.0 | 5.36e-01 | 100.0% | 93.2% |
| 3231048 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.63 | 33.0 | 4.09e-01 | 91.4% | 79.3% |
| 2667749 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.62 | 56.0 | 5.43e-01 | 99.5% | 88.0% |
| 3221738 | 192.29.1.172 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 | 0.61 | 34.0 | 4.23e-01 | 88.6% | 86.4% |
| 3272619 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.61 | 34.0 | 4.51e-01 | 86.4% | 100.0% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 38.0 | 4.64e-01 | 90.5% | 94.6% |
| 3643409 | 5001.1.1.80 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Dicty_CAR | 0.59 | 54.0 | 4.85e-01 | 99.5% | 85.9% |
| 3582897 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.58 | 41.0 | 4.22e-01 | 98.2% | 73.5% |
| 3289077 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.56 | 33.0 | 4.22e-01 | 84.1% | 100.0% |
| 3473688 | 3567.1.1.82 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Frag1 | 0.55 | 48.0 | 4.70e-01 | 91.8% | 100.0% |
| 3200053 | 1174.1.1.0 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 | 0.51 | 42.0 | 4.46e-01 | 89.1% | 97.4% |