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hypothetical_protein_pv_280

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_280__YP_009001182__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001182 ↗
Protein ID:
hypothetical_protein_pv_280
Kingdom:
euk

Quality

66.0 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (3 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 10-59
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1lkvX02 1.10.220.30 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain 0.74 61.0 4.50e-01 92.0% 36.4%
D2 medium residues 60-119
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bbyA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 41.0 3.93e-01 96.7% 58.0%
1d1lA00 3.30.240.10 Alpha Beta › 2-Layer Sandwich › CRO Repressor › CRO Repressor 0.62 39.0 3.94e-01 100.0% 62.3%
3cjnA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 44.0 3.33e-01 96.7% 30.8%
4ne4A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.62 46.0 3.44e-01 81.7% 43.1%
4izzB03 1.10.10.1670 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › HetR, flap domain 0.60 51.0 4.17e-01 96.7% 54.8%
3o66B01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.59 44.0 3.29e-01 83.3% 42.9%
2qxfA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.58 39.0 2.80e-01 70.0% 97.9%
1e6vB02 1.20.840.10 Mainly Alpha › Up-down Bundle › Methyl-coenzyme M Reductase; Chain B, domain 2 › Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal 0.58 43.0 2.82e-01 81.7% 20.4%
2xzn800 3.30.63.20 Alpha Beta › 2-Layer Sandwich › Guanylate Kinase phosphate binding domain › 0.58 42.0 3.67e-01 96.7% 50.5%
4rayA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 44.0 3.97e-01 98.3% 60.0%
3eyyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 45.0 4.12e-01 98.3% 63.4%
1u5tB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 43.0 4.19e-01 96.7% 73.9%
7bqiA01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.56 45.0 3.49e-01 93.3% 68.2%
2co5A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 44.0 3.89e-01 98.3% 57.6%
2xigA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 42.0 3.74e-01 96.7% 56.0%
3mwmA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 40.0 3.85e-01 96.7% 65.3%
2lsoA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 44.0 4.00e-01 98.3% 65.1%
2fe3B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 41.0 3.68e-01 95.0% 58.8%
7uvpA02 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.54 42.0 4.02e-01 85.0% 95.7%
2hlyA00 3.10.550.10 Alpha Beta › Roll › Atu2299-like › Hypothetical protein Atu2299 0.53 40.0 2.83e-01 83.3% 76.6%
1qr0A02 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.53 36.0 3.13e-01 71.7% 42.7%
2b0lC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.42e-01 80.0% 79.8%
3jcmH04 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.53 41.0 3.81e-01 86.7% 87.0%
4hstA01 1.10.439.10 Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Penicillin Amidohydrolase, domain 1 0.52 37.0 2.89e-01 78.3% 83.4%
3zcoA00 1.10.10.2450 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.52 40.0 3.28e-01 90.0% 89.0%
5hvqC01 3.90.1150.220 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.52 42.0 3.92e-01 95.0% 71.2%
4esbA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 40.0 3.46e-01 96.7% 52.4%
8dkrB01 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.52 39.0 2.69e-01 83.3% 36.2%
2wa0A01 1.10.10.1200 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › MAGE homology domain, winged helix WH1 motif 0.51 37.0 3.17e-01 91.7% 46.5%
1fpqA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 40.0 3.20e-01 95.0% 41.1%
3uoxB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 42.0 2.81e-01 100.0% 57.6%
3a2kA03 3.30.465.60 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.50 37.0 3.30e-01 78.3% 79.1%
1twuA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.50 39.0 3.05e-01 86.7% 70.1%
3kolA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.50 38.0 2.99e-01 88.3% 37.9%
3u5eU00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.50 38.0 3.36e-01 88.3% 91.0%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4232356 101.1.2.517 ↗ alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.69 50.0 2.88e-01 96.7% 8.7%
3630104 192.24.1.6 ↗ alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.68 50.0 3.08e-01 98.3% 12.6%
4951019 101.1.2.896 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF2551 0.63 45.0 3.99e-01 80.0% 81.1%
3200036 101.1.2.407 ↗ alpha arrays › HTH › HTH › winged helix domain › WHD_ORC2 0.62 47.0 3.64e-01 96.7% 35.7%
5028058 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.61 40.0 3.20e-01 95.0% 33.3%
3178207 101.1.2.774 ↗ alpha arrays › HTH › HTH › winged helix domain › PF30201 0.60 45.0 3.30e-01 96.7% 28.6%
3272300 2484.1.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.60 45.0 2.83e-01 86.7% 83.9%
5018509 2008.1.1.15 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N 0.59 40.0 2.70e-01 71.7% 40.0%
2702235 101.1.2.407 ↗ alpha arrays › HTH › HTH › winged helix domain › WHD_ORC2 0.59 45.0 3.78e-01 96.7% 46.4%
3516922 5067.1.1.3 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched 0.59 35.0 1.98e-01 76.7% 4.4%
5042592 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.58 50.0 3.59e-01 100.0% 36.8%
3924514 109.4.1.83 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf 0.58 39.0 2.57e-01 71.7% 26.6%
4110582 140.1.1.14 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.58 44.0 3.19e-01 86.7% 87.1%
5000571 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.58 46.0 4.25e-01 98.3% 67.5%
135163 101.1.2.25 ↗ alpha arrays › HTH › HTH › winged helix domain › FUR 0.57 45.0 3.52e-01 98.3% 39.1%
3482761 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 43.0 2.75e-01 86.7% 85.1%
3473648 101.1.2.312 ↗ alpha arrays › HTH › HTH › winged helix domain › MSC 0.57 43.0 2.82e-01 98.3% 17.9%
4655040 140.1.1.4 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.57 43.0 3.00e-01 85.0% 90.1%
3466949 101.1.2.524 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF7625 0.57 43.0 3.55e-01 96.7% 44.3%
5028329 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 44.0 4.15e-01 95.0% 69.3%
3197950 256.1.1.0 ↗ a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like 0.56 35.0 3.90e-01 95.0% 84.4%
3366576 2003.1.6.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Misat_Tub_SegII+Tubulin_3 0.56 37.0 2.49e-01 70.0% 96.1%
1407164 2484.1.1.3 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin,Thymosin 0.56 44.0 3.10e-01 91.7% 70.8%
4646939 2484.1.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.56 41.0 2.85e-01 83.3% 84.0%
3301960 2484.1.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.56 43.0 3.02e-01 91.7% 63.5%
4977547 101.1.2.78 ↗ alpha arrays › HTH › HTH › winged helix domain › AlkZ-like 0.55 41.0 3.74e-01 100.0% 58.8%
5082110 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.55 41.0 4.11e-01 91.7% 81.7%
4982982 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.54 43.0 3.23e-01 100.0% 69.5%
4137380 140.1.1.4 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.54 41.0 2.94e-01 88.3% 88.3%
3402524 101.1.2.186 ↗ alpha arrays › HTH › HTH › winged helix domain › ASH2L-like_WH 0.54 44.0 3.91e-01 96.7% 64.2%
3283276 2484.1.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.54 44.0 3.23e-01 96.7% 72.4%
3493460 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 40.0 3.49e-01 85.0% 87.0%
3942501 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 44.0 3.88e-01 98.3% 61.1%
4992788 2484.1.1.139 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF429 0.53 43.0 3.17e-01 100.0% 73.0%
3638956 101.1.2.309 ↗ alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.53 44.0 3.42e-01 98.3% 44.0%
4941351 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 42.0 3.84e-01 96.7% 63.5%
4942265 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 40.0 3.64e-01 91.7% 58.8%
4363280 601.1.2.53 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DGKD_4H 0.53 41.0 3.10e-01 86.7% 75.6%
3925904 101.1.2.57 ↗ alpha arrays › HTH › HTH › winged helix domain › EAP30 0.53 37.0 2.77e-01 76.7% 45.1%
5046292 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.52 39.0 3.61e-01 83.3% 86.3%
3744213 101.1.2.57 ↗ alpha arrays › HTH › HTH › winged helix domain › EAP30 0.52 39.0 3.14e-01 95.0% 37.1%
5001357 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.52 45.0 3.82e-01 98.3% 67.0%
4937876 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.52 39.0 3.17e-01 96.7% 40.8%
4645593 140.1.1.0 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.52 42.0 3.19e-01 88.3% 100.0%
3784236 807.1.1.0 ↗ a+b two layers › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) 0.52 39.0 3.21e-01 81.7% 50.0%
3802667 101.1.2.88 ↗ alpha arrays › HTH › HTH › winged helix domain › Dimerisation 0.52 41.0 3.46e-01 96.7% 50.5%
3605475 140.1.1.14 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.51 40.0 2.75e-01 88.3% 88.7%
3260966 70.3.1.0 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like 0.51 40.0 2.52e-01 86.7% 33.4%
3590781 101.1.2.92 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.51 36.0 3.27e-01 96.7% 52.2%
5035276 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.51 44.0 3.87e-01 98.3% 65.6%
4890753 4342.1.1.2 ↗ alpha complex topology › Tex N-terminal region-like › Tex N-terminal region-like › Tex N-terminal region-like › YqgF 0.51 35.0 2.50e-01 73.3% 26.9%
3714022 304.24.1.3 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.50 37.0 3.70e-01 78.3% 83.3%
3990034 101.1.2.92 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.50 35.0 3.23e-01 96.7% 52.2%
3785490 101.1.2.57 ↗ alpha arrays › HTH › HTH › winged helix domain › EAP30 0.50 41.0 3.19e-01 96.7% 39.3%
3632795 101.1.2.309 ↗ alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.50 43.0 3.57e-01 96.7% 61.8%
4522308 101.1.2.654 ↗ alpha arrays › HTH › HTH › winged helix domain › RPA 0.50 37.0 3.43e-01 95.0% 61.3%
5052340 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.50 39.0 3.74e-01 96.7% 72.9%
D3 medium residues 120-219
PDB