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hypothetical_protein_pv_282
Euk-VirPithovirus_sibericum
hypothetical_protein_pv_282__YP_009001184__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001184 ↗
- Protein ID:
- hypothetical_protein_pv_282
- Kingdom:
- euk
Quality
70.3
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 101-167
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3bg1B03 | 1.25.40.690 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 45.0 | 4.11e-01 | 77.6% | 83.7% |
| 3vwaA03 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.60 | 51.0 | 3.42e-01 | 100.0% | 29.9% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.57 | 38.0 | 3.58e-01 | 70.1% | 94.1% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.55 | 37.0 | 3.17e-01 | 70.1% | 73.5% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.55 | 37.0 | 3.33e-01 | 71.6% | 76.5% |
| 3efzB00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.55 | 47.0 | 3.34e-01 | 100.0% | 76.9% |
| 7k18A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.54 | 41.0 | 3.37e-01 | 86.6% | 70.1% |
| 1tfkB00 | 1.20.120.650 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Colicin D | 0.53 | 39.0 | 3.61e-01 | 80.6% | 60.5% |
| 7odyC01 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.53 | 38.0 | 3.54e-01 | 79.1% | 72.8% |
| 5hayA02 | 1.25.40.440 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain | 0.52 | 42.0 | 4.11e-01 | 100.0% | 82.3% |
| 2o57A01 | 1.10.287.840 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mycolic acid cyclopropane synthase domain like | 0.51 | 38.0 | 3.33e-01 | 80.6% | 78.1% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1066041 | 7525.1.1.2 ↗ | a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › His_Phos_2 | 0.54 | 45.0 | 2.87e-01 | 94.0% | 35.5% |
| 3296396 | 109.59.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain | 0.54 | 44.0 | 4.36e-01 | 95.5% | 93.3% |
| 3190266 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 40.0 | 2.68e-01 | 80.6% | 23.0% |
| 3343787 | 109.4.1.1374 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, TPR_24 | 0.52 | 43.0 | 3.44e-01 | 100.0% | 45.0% |
| 3609839 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 43.0 | 3.30e-01 | 100.0% | 80.0% |
D2
medium
residues 29-82
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3tjmA02 | 1.10.1470.20 | Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › Fatty acid synthase; domain 2 | 0.69 | 55.0 | 4.68e-01 | 88.9% | 57.8% |
| 1xb2B01 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.65 | 45.0 | 4.44e-01 | 77.8% | 66.7% |
| 2l4eA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.64 | 45.0 | 4.43e-01 | 77.8% | 70.2% |
| 2dzlA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.62 | 47.0 | 4.45e-01 | 85.2% | 68.2% |
| 2gicD02 | 1.10.3610.10 | Mainly Alpha › Orthogonal Bundle › Rhabdovirus nucleoprotein-like › Nucleoprotein | 0.61 | 49.0 | 3.54e-01 | 100.0% | 96.4% |
| 5ekdA02 | 1.10.240.10 | Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase | 0.60 | 46.0 | 3.83e-01 | 90.7% | 85.6% |
| 2ltuA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.59 | 41.0 | 3.95e-01 | 72.2% | 66.1% |
| 1vhnA02 | 1.10.1200.80 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Putative flavin oxidoreducatase; domain 2 | 0.58 | 44.0 | 4.09e-01 | 85.2% | 85.9% |
| 2b0cA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.55 | 42.0 | 3.99e-01 | 85.2% | 89.4% |
| 4rslA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.53 | 42.0 | 2.92e-01 | 98.1% | 91.2% |
| 1j1vA00 | 1.10.1750.10 | Mainly Alpha › Orthogonal Bundle › Chromosomal Replication Initiator Protein Dnaa; Chain: A; › DnaA protein, C-terminal DNA-binding domain | 0.52 | 41.0 | 3.49e-01 | 90.7% | 90.4% |
| 3fyaB00 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.51 | 41.0 | 3.77e-01 | 96.3% | 81.8% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 40.0 | 2.64e-01 | 88.9% | 77.0% |
| 1x57A00 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.51 | 40.0 | 3.50e-01 | 92.6% | 75.8% |
| 2xepB02 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.50 | 40.0 | 2.73e-01 | 100.0% | 50.0% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3399890 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.81 | 58.0 | 6.28e-01 | 75.9% | 93.3% |
| 3814623 | 145.1.1.0 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain | 0.69 | 53.0 | 4.78e-01 | 87.0% | 58.7% |
| 4019989 | 103.1.1.14 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › UBA_4 | 0.67 | 48.0 | 4.65e-01 | 79.6% | 68.3% |
| 3748786 | 110.1.1.1 ↗ | alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death | 0.65 | 51.0 | 4.23e-01 | 90.7% | 48.6% |
| 4028162 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.65 | 45.0 | 4.61e-01 | 75.9% | 78.0% |
| 4025664 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.63 | 44.0 | 4.58e-01 | 77.8% | 80.0% |
| 3727160 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.62 | 45.0 | 4.12e-01 | 79.6% | 64.0% |
| 4514726 | 3317.1.1.0 ↗ | alpha arrays › KorB C-terminal domain-like › KorB C-terminal domain › KorB C-terminal domain | 0.61 | 44.0 | 4.20e-01 | 79.6% | 70.8% |
| 3216889 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.58 | 41.0 | 4.29e-01 | 83.3% | 97.8% |
| 3484342 | 193.1.1.0 ↗ | alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like | 0.57 | 45.0 | 4.05e-01 | 100.0% | 68.2% |
| 4391132 | 7510.1.1.1 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh | 0.56 | 43.0 | 3.01e-01 | 90.7% | 73.5% |
| 4930125 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.55 | 41.0 | 2.80e-01 | 83.3% | 28.0% |
| 3282040 | 101.1.4.18 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_31 | 0.51 | 41.0 | 3.56e-01 | 96.3% | 57.6% |
D3
medium
residues 168-226
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2wglA00 | 1.10.4190.10 | Mainly Alpha › Orthogonal Bundle › Urease accessory protein UreF › Urease accessory protein UreF | 0.61 | 44.0 | 3.03e-01 | 76.3% | 78.9% |
| 3ha4B00 | 1.20.58.690 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 51.0 | 4.19e-01 | 100.0% | 67.5% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.60 | 41.0 | 3.74e-01 | 72.9% | 83.5% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.59 | 43.0 | 3.84e-01 | 81.4% | 83.1% |
| 2b6cA02 | 1.25.40.290 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat domains | 0.57 | 47.0 | 4.17e-01 | 100.0% | 72.2% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 45.0 | 2.89e-01 | 93.2% | 51.3% |
| 2idgA00 | 1.10.3480.10 | Mainly Alpha › Orthogonal Bundle › TorD-like › TorD-like | 0.55 | 42.0 | 3.19e-01 | 86.4% | 57.9% |
| 2dlaA01 | 1.20.930.50 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.55 | 44.0 | 3.39e-01 | 94.9% | 66.9% |
| 2w0gA00 | 1.20.58.610 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain | 0.55 | 44.0 | 3.61e-01 | 96.6% | 93.0% |
| 6ll8A01 | 3.90.1640.10 | Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › inorganic pyrophosphatase (n-terminal core) | 0.54 | 44.0 | 3.26e-01 | 98.3% | 89.2% |
| 3qbeA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.54 | 36.0 | 2.65e-01 | 71.2% | 87.4% |
| 5lb3B02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 43.0 | 3.06e-01 | 100.0% | 78.9% |
| 4dq5B00 | 1.10.530.50 | Mainly Alpha › Orthogonal Bundle › Lysozyme › Peptidase U40 | 0.52 | 37.0 | 2.76e-01 | 100.0% | 27.5% |
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.52 | 42.0 | 2.80e-01 | 93.2% | 98.1% |
| 2vm6A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.52 | 36.0 | 2.83e-01 | 72.9% | 44.4% |
| 2lyiA01 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.50 | 39.0 | 3.13e-01 | 94.9% | 92.6% |
| 1anxA04 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.50 | 40.0 | 3.87e-01 | 98.3% | 100.0% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4609 | 109.4.1.124 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_alkylation | 0.59 | 48.0 | 3.42e-01 | 100.0% | 41.8% |
| 4200315 | 604.6.1.59 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PigN | 0.57 | 40.0 | 3.18e-01 | 76.3% | 70.4% |
| 3695367 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 46.0 | 3.35e-01 | 100.0% | 67.8% |
| 3709421 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.56 | 40.0 | 3.57e-01 | 76.3% | 84.7% |
| 4656935 | 601.4.1.51 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PigN | 0.55 | 41.0 | 3.12e-01 | 83.1% | 65.8% |
| 2035869 | 4002.1.1.3 ↗ | alpha bundles › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › Fe-ADH_2 | 0.54 | 45.0 | 2.91e-01 | 100.0% | 56.2% |
| 3067438 | 2488.1.1.3 ↗ | a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › tRNA_m1G_MT | 0.53 | 38.0 | 2.61e-01 | 79.7% | 57.7% |
| 3487928 | 3277.2.1.0 ↗ | alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 | 0.52 | 38.0 | 3.16e-01 | 81.4% | 70.4% |
| 4670553 | 150.1.1.106 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PigN | 0.51 | 43.0 | 3.32e-01 | 98.3% | 63.3% |
| 3728304 | 604.12.1.24 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6604 | 0.51 | 38.0 | 3.33e-01 | 86.4% | 77.0% |
D4
medium
residues 257-339
D5
medium
residues 340-424