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hypothetical_protein_pv_284
Euk-VirPithovirus_sibericum
hypothetical_protein_pv_284__YP_009001186__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001186 ↗
- Protein ID:
- hypothetical_protein_pv_284
- Kingdom:
- euk
Quality
76.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
View cluster (6 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-47
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 56.0 | 4.63e-01 | 73.3% | 98.7% |
| 2fsjA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.78 | 55.0 | 3.86e-01 | 75.6% | 68.8% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.77 | 63.0 | 4.62e-01 | 91.1% | 85.1% |
| 5yjlC02 | 3.20.180.10 | Alpha Beta › Alpha-Beta Barrel › Split barrel-like › PNP-oxidase-like | 0.74 | 65.0 | 4.80e-01 | 97.8% | 82.9% |
| 2bskB00 | 1.10.287.810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains | 0.74 | 54.0 | 4.72e-01 | 77.8% | 64.6% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.74 | 55.0 | 4.12e-01 | 80.0% | 82.7% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.73 | 50.0 | 5.05e-01 | 71.1% | 80.0% |
| 2oznB01 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.72 | 64.0 | 5.30e-01 | 100.0% | 95.0% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.71 | 55.0 | 3.77e-01 | 84.4% | 42.8% |
| 2iw1A01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.70 | 53.0 | 3.55e-01 | 84.4% | 39.7% |
| 1jb0K00 | 1.20.860.20 | Mainly Alpha › Up-down Bundle › Alpha-t-alpha › Photosystem I PsaK, reaction centre | 0.69 | 49.0 | 4.88e-01 | 75.6% | 95.7% |
| 2xzmV01 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.69 | 47.0 | 4.20e-01 | 71.1% | 70.5% |
| 1q8iA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.68 | 61.0 | 3.89e-01 | 100.0% | 42.6% |
| 3swhA01 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.68 | 59.0 | 4.00e-01 | 100.0% | 54.5% |
| 3u5nA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.68 | 55.0 | 4.21e-01 | 100.0% | 71.7% |
| 4iw7A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.68 | 54.0 | 4.20e-01 | 97.8% | 78.3% |
| 3d5lB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.65 | 56.0 | 4.36e-01 | 100.0% | 62.7% |
| 6f7hA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.65 | 57.0 | 3.52e-01 | 95.6% | 93.2% |
| 1bvp103 | 1.10.170.10 | Mainly Alpha › Orthogonal Bundle › Bluetongue Virus 10, subunit 1; domain 3 › Bluetongue Virus 10, subunit 1, domain 3 | 0.63 | 54.0 | 4.28e-01 | 100.0% | 71.9% |
| 3s6jE02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.62 | 47.0 | 4.18e-01 | 84.4% | 63.8% |
| 1x1fA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.62 | 53.0 | 3.73e-01 | 100.0% | 32.2% |
| 2lfhA00 | 4.10.280.10 | Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain | 0.61 | 47.0 | 4.19e-01 | 88.9% | 57.4% |
| 1whqA01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.61 | 52.0 | 4.47e-01 | 95.6% | 71.8% |
| 2hmcA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.61 | 53.0 | 3.17e-01 | 97.8% | 15.6% |
| 1a3qA01 | 2.60.40.340 | Mainly Beta › Sandwich › Immunoglobulin-like › Rel homology domain (RHD), DNA-binding domain | 0.59 | 48.0 | 3.27e-01 | 93.3% | 62.0% |
| 7jgsG01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 45.0 | 3.17e-01 | 93.3% | 23.6% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 48.0 | 3.85e-01 | 91.1% | 52.9% |
| 3dorA02 | 2.30.42.10 | Mainly Beta › Roll › Pdz3 Domain › PDZ domain | 0.58 | 46.0 | 3.59e-01 | 91.1% | 86.0% |
| 2cdqA03 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.57 | 43.0 | 3.67e-01 | 88.9% | 82.1% |
| 1a5kC02 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.57 | 47.0 | 2.77e-01 | 93.3% | 66.4% |
| 3b4sA01 | 1.10.287.790 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › luxt domain from vibrio parahaemolyticus | 0.57 | 38.0 | 3.78e-01 | 71.1% | 65.3% |
| 1jqgA01 | 3.30.70.340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like | 0.57 | 44.0 | 3.60e-01 | 88.9% | 61.5% |
| 2kngA01 | 4.10.320.10 | Few Secondary Structures › Irregular › Dihydrolipoamide Transferase › E3-binding domain | 0.52 | 39.0 | 4.03e-01 | 91.1% | 100.0% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3421107 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.89 | 61.0 | 6.11e-01 | 71.1% | 82.2% |
| 3613495 | 2498.5.1.0 ↗ | mixed a+b and a/b › Zincin-like › GroEL-intermediate domain like › GroEL-intermediate domain like | 0.87 | 57.0 | 4.61e-01 | 80.0% | 38.7% |
| 4193561 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.85 | 58.0 | 5.86e-01 | 71.1% | 82.2% |
| 4965149 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.84 | 57.0 | 5.53e-01 | 71.1% | 74.0% |
| 4387547 | 7013.1.1.1 ↗ | alpha bundles › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Efg1 | 0.84 | 58.0 | 3.68e-01 | 71.1% | 19.5% |
| 4078439 | 152.1.2.1 ↗ | alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 | 0.79 | 48.0 | 4.15e-01 | 91.1% | 43.1% |
| None | — | 0.79 | 67.0 | 3.71e-01 | 100.0% | 7.3% | |
| 3557037 | 109.4.1.893 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UTP6_C | 0.78 | 55.0 | 3.74e-01 | 75.6% | 24.4% |
| 4311410 | 152.1.2.1 ↗ | alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 | 0.77 | 47.0 | 4.13e-01 | 91.1% | 43.1% |
| 3489093 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.75 | 65.0 | 4.00e-01 | 95.6% | 21.2% |
| 3776835 | 109.4.1.933 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Trm732 | 0.69 | 59.0 | 3.68e-01 | 93.3% | 40.0% |
| 4985531 | 152.1.2.1 ↗ | alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 | 0.69 | 43.0 | 3.90e-01 | 88.9% | 48.3% |
| 3686247 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 63.0 | 3.54e-01 | 100.0% | 31.9% |
| 5003499 | 109.3.1.484 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF2238 | 0.69 | 55.0 | 3.56e-01 | 97.8% | 33.8% |
| 3713159 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.67 | 59.0 | 4.32e-01 | 100.0% | 85.0% |
| 4991735 | 210.1.3.0 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases | 0.66 | 47.0 | 3.07e-01 | 80.0% | 15.7% |
| 3244328 | 3340.1.1.0 ↗ | extended segments › Helical region in REST corepressor 1 › Helical region in REST corepressor 1 › Helical region in REST corepressor 1 | 0.63 | 47.0 | 4.21e-01 | 77.8% | 65.0% |
| 3442602 | 101.1.2.386 ↗ | alpha arrays › HTH › HTH › winged helix domain › WH_DRP | 0.61 | 44.0 | 3.38e-01 | 77.8% | 42.0% |
| 4017561 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 50.0 | 2.99e-01 | 100.0% | 14.6% |
D2
high
residues 63-196
Domain cluster:
rep: hypothetical_protein_pv_285__YP_009001187__Pithovirus_sibericum__1450746__D68-212
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1iz6A01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.77 | 26.0 | 3.68e-01 | 81.3% | 60.9% |
| 8aimG01 | 3.10.450.20 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor | 0.72 | 35.0 | 4.41e-01 | 88.8% | 76.5% |
| 2fblB00 | 2.40.320.10 | Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 | 0.71 | 33.0 | 3.18e-01 | 100.0% | 39.9% |
| 4pj2A00 | 2.40.128.460 | Mainly Beta › Beta Barrel › Lipocalin › Periplasmic lysozyme inhibitor of I-type lysozyme | 0.67 | 33.0 | 3.47e-01 | 93.3% | 51.2% |
| 2qkdA03 | 2.20.25.420 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain | 0.65 | 27.0 | 4.17e-01 | 84.3% | 100.0% |
| 2h36X00 | 3.30.160.300 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.64 | 28.0 | 3.10e-01 | 86.6% | 48.1% |
| 2imjD01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.64 | 40.0 | 3.95e-01 | 99.3% | 59.2% |
| 2qkdA01 | 2.20.25.420 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain | 0.60 | 23.0 | 3.75e-01 | 79.9% | 100.0% |
| 1t4lB00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.59 | 28.0 | 3.33e-01 | 70.9% | 64.4% |
| 4htgA03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.54 | 29.0 | 3.56e-01 | 92.5% | 84.8% |
| 2z4hA01 | 2.40.128.300 | Mainly Beta › Beta Barrel › Lipocalin › NlpE, N-terminal domain | 0.54 | 31.0 | 3.84e-01 | 97.8% | 94.9% |
| 3ebwA01 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.51 | 37.0 | 3.70e-01 | 98.5% | 72.5% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3947188 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.82 | 41.0 | 4.68e-01 | 95.5% | 62.9% |
| 3890539 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.75 | 35.0 | 5.07e-01 | 94.8% | 100.0% |
| 5035338 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.74 | 41.0 | 3.81e-01 | 100.0% | 43.5% |
| 4257113 | 295.1.1.27 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PF25991 | 0.73 | 34.0 | 4.53e-01 | 96.3% | 82.9% |
| 4974435 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.68 | 37.0 | 4.33e-01 | 100.0% | 74.7% |
| 5045102 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.67 | 29.0 | 3.42e-01 | 84.3% | 55.8% |
| 3287567 | 4312.1.1.0 ↗ | a+b two layers › RelE-like › RelE-like › RelE-like | 0.67 | 34.0 | 4.09e-01 | 94.8% | 72.2% |
| 5038381 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.67 | 33.0 | 3.48e-01 | 91.8% | 51.2% |
| 3215377 | 5.1.4.62 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PROPPIN | 0.67 | 30.0 | 2.20e-01 | 90.3% | 15.3% |
| 5014272 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.66 | 35.0 | 4.63e-01 | 95.5% | 97.1% |
| 3502044 | 243.19.1.0 ↗ | a+b two layers › Cystatin-like › Phi ETA orf 56-like protein C-terminal domains › Phi ETA orf 56-like protein C-terminal domains | 0.65 | 31.0 | 3.43e-01 | 85.8% | 55.2% |
| 4804225 | 9.1.1.11 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin_2 | 0.65 | 33.0 | 4.06e-01 | 89.6% | 75.9% |
| 3702663 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.62 | 31.0 | 3.02e-01 | 93.3% | 42.8% |
| 4054729 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.62 | 28.0 | 3.62e-01 | 87.3% | 73.3% |
| 4028798 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.60 | 35.0 | 3.32e-01 | 86.6% | 46.1% |
| 3969722 | 6043.1.1.0 ↗ | a+b two layers › yfeY-like › yfeY-like › yfeY-like | 0.60 | 25.0 | 3.26e-01 | 85.8% | 67.1% |
| 2141377 | 5087.1.1.4 ↗ | beta meanders › Lipovitellin-phosvitin complex › Lipovitellin LV-2 › Lipovitellin LV-2 › DUF481, Porin_OmpG | 0.59 | 36.0 | 2.78e-01 | 86.6% | 28.1% |
| 3282412 | 4312.1.1.4 ↗ | a+b two layers › RelE-like › RelE-like › RelE-like › Gp49 | 0.58 | 31.0 | 3.28e-01 | 91.0% | 56.9% |
| 3232806 | 216.1.1.26 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › FmiP_Thoc5 | 0.55 | 30.0 | 2.96e-01 | 76.9% | 46.7% |
| 3916012 | 192.29.1.276 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FmiP_Thoc5 | 0.54 | 32.0 | 2.89e-01 | 80.6% | 41.6% |
| 222972 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.54 | 29.0 | 3.42e-01 | 92.5% | 75.3% |
| 4216680 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.54 | 27.0 | 3.19e-01 | 91.0% | 66.7% |
| 3226744 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.53 | 34.0 | 3.97e-01 | 100.0% | 95.6% |
| 3957605 | 243.1.1.35 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › ORF_12_N | 0.52 | 33.0 | 3.80e-01 | 90.3% | 90.5% |