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hypothetical_protein_pv_298

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_298__YP_009001200__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001200 ↗
Protein ID:
hypothetical_protein_pv_298
Kingdom:
euk

Quality

74.7 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (6 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 45-83_146-201
PDB
Domain cluster: representative
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yemB00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.73 52.0 4.31e-01 87.4% 42.8%
4exrA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.68 41.0 4.40e-01 71.6% 70.4%
2ffgA00 3.30.720.20 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Protein of unknown function DUF1797 0.67 48.0 5.21e-01 95.8% 90.0%
4hgzA02 2.20.25.570 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.66 39.0 4.66e-01 81.1% 91.7%
3esiA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.66 48.0 4.40e-01 76.8% 90.3%
4l9cA00 3.40.1000.30 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › 0.63 41.0 3.50e-01 71.6% 42.0%
1p32B00 3.10.280.10 Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein 0.63 40.0 3.32e-01 80.0% 35.7%
1ugiD00 3.10.450.20 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor 0.63 43.0 4.57e-01 70.5% 86.6%
5a67A00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.62 50.0 3.88e-01 87.4% 51.0%
1egxA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.62 50.0 4.72e-01 87.4% 90.4%
3bxoA02 2.20.130.10 Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › CAC2371-like domains 0.62 37.0 4.53e-01 80.0% 96.6%
2d42A02 3.10.450.380 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 40.0 4.65e-01 88.4% 98.5%
3stoA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.60 42.0 3.61e-01 72.6% 91.1%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.59 48.0 4.17e-01 86.3% 92.9%
2eigA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.59 53.0 3.99e-01 100.0% 76.1%
1uuzB00 3.40.1420.10 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › Inhibitor of vertebrate lysozyme 0.58 43.0 3.85e-01 76.8% 74.2%
5t5lA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.58 52.0 3.95e-01 100.0% 74.7%
2oq8A00 2.60.40.2930 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 47.0 4.10e-01 92.6% 70.7%
4ae8D00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.56 44.0 3.63e-01 83.2% 81.8%
2gr7A00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.56 35.0 3.44e-01 81.1% 58.4%
3pieB05 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.56 37.0 4.22e-01 96.8% 100.0%
1gkaB00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.55 49.0 4.05e-01 100.0% 67.2%
3v8uA02 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.55 49.0 4.00e-01 100.0% 97.2%
2m47A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 36.0 2.99e-01 77.9% 38.7%
6gbuD00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.55 36.0 4.16e-01 83.2% 98.4%
3a1jB00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.55 45.0 3.26e-01 89.5% 95.9%
3ci0K01 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.55 37.0 3.62e-01 87.4% 63.5%
3gp6A00 2.40.160.20 Mainly Beta › Beta Barrel › Porin › 0.54 42.0 3.54e-01 82.1% 67.1%
1vavA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.54 48.0 3.68e-01 100.0% 50.5%
6nu7A01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 44.0 3.11e-01 92.6% 69.9%
2owpA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 40.0 3.65e-01 81.1% 87.6%
5w8mA00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.53 36.0 2.86e-01 70.5% 98.0%
4oocA00 3.10.129.110 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase 0.53 44.0 3.24e-01 92.6% 70.1%
3w9aA00 2.60.120.1160 Mainly Beta › Sandwich › Jelly Rolls › 0.53 46.0 3.53e-01 100.0% 59.1%
3h27A00 3.50.50.100 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › 0.53 45.0 2.96e-01 95.8% 83.0%
1plqA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.53 39.0 2.95e-01 80.0% 94.6%
1n7vA02 2.60.330.10 Mainly Beta › Sandwich › receptor-binding protein prd1-p2, domain 2 › receptor-binding protein prd1-p2, domain 2 0.53 42.0 3.85e-01 85.3% 89.4%
3nctA00 3.40.50.11880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Plasmid SOS inhibition protein 0.52 45.0 4.04e-01 95.8% 83.9%
3holA02 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.52 47.0 3.91e-01 100.0% 93.4%
3uaqB02 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.52 42.0 3.59e-01 88.4% 96.3%
4eg9A00 2.50.20.40 Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › 0.52 46.0 3.52e-01 100.0% 87.4%
3pquA02 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.52 46.0 3.79e-01 100.0% 93.8%
3wjcA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.52 45.0 3.93e-01 100.0% 94.1%
3pg7A02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 41.0 3.91e-01 86.3% 74.5%
6mlyB01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.51 42.0 3.14e-01 92.6% 84.4%
4bgjA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.51 36.0 3.43e-01 75.8% 80.5%
1vq0A01 3.55.30.10 Alpha Beta › 3-Layer(bab) Sandwich › Hsp33 domain › Hsp33 domain 0.50 43.0 3.27e-01 95.8% 85.0%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3559516 391.1.1.28 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › CHRDL_1_2_C 0.73 47.0 4.63e-01 90.5% 62.0%
5014253 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.72 42.0 4.86e-01 72.6% 80.0%
5042040 868.1.1.1 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.72 53.0 4.33e-01 86.3% 43.5%
4983274 868.1.1.1 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.71 55.0 4.43e-01 86.3% 44.0%
3165974 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.68 38.0 3.62e-01 76.8% 47.3%
3947082 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.68 46.0 4.80e-01 84.2% 74.4%
3269422 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.67 46.0 3.31e-01 78.9% 25.2%
3242315 145.1.1.0 ↗ alpha arrays › F-box domain › F-box domain › F-box domain 0.66 38.0 4.91e-01 73.7% 100.0%
1423566 331.4.1.3 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › AdenylateSensor 0.65 37.0 4.13e-01 71.6% 71.1%
3409342 101.1.12.3 ↗ alpha arrays › HTH › HTH › HTH motif inserted in other structures › SAS-6_N 0.63 50.0 4.37e-01 84.2% 68.6%
4321969 222.1.1.0 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.62 47.0 3.95e-01 81.1% 81.8%
3215014 632.22.1.184 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › SMC_N 0.62 55.0 3.48e-01 100.0% 79.6%
3791220 4210.1.1.1 ↗ a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.62 52.0 4.76e-01 91.6% 93.5%
3793430 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.62 32.0 3.26e-01 75.8% 49.5%
3484248 4210.1.1.0 ↗ a+b two layers › WGR domain › WGR domain › WGR domain 0.61 51.0 4.72e-01 89.5% 85.0%
3905709 243.3.1.22 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Cyto_heme_lyase 0.61 44.0 3.54e-01 74.7% 93.9%
3239667 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.61 54.0 3.25e-01 100.0% 89.2%
3193765 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 50.0 4.30e-01 88.4% 86.0%
3732226 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 50.0 4.17e-01 88.4% 88.7%
3434817 4210.1.1.1 ↗ a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.61 51.0 4.68e-01 90.5% 100.0%
5035423 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.60 45.0 4.71e-01 93.7% 87.1%
3591269 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.60 49.0 3.40e-01 88.4% 71.2%
3924939 4210.1.1.1 ↗ a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.60 50.0 4.70e-01 90.5% 87.0%
4974745 219.1.1.153 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › BtrH_N 0.59 52.0 4.19e-01 100.0% 49.5%
3370179 10.1.1.2 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB 0.59 53.0 3.83e-01 100.0% 67.8%
3453561 10.1.1.2 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB 0.58 52.0 3.81e-01 96.8% 74.3%
3923143 633.23.1.17 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › DuoxA 0.58 48.0 3.56e-01 89.5% 68.8%
3363098 295.1.1.5 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › Whirly 0.58 47.0 4.61e-01 87.4% 82.9%
3742310 5.1.4.38 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › ANAPC1 0.58 46.0 3.18e-01 84.2% 52.5%
3392728 331.9.1.8 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › AP3B1_C_2 0.58 43.0 3.93e-01 78.9% 81.6%
3579989 5.1.4.116 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › IKI3 0.58 51.0 3.39e-01 95.8% 87.2%
3199763 220.1.1.202 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_FT_N 0.58 47.0 4.26e-01 86.3% 72.8%
3763789 220.1.1.186 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_CAYP2 0.57 47.0 4.06e-01 88.4% 74.5%
3917645 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 46.0 4.31e-01 87.4% 85.8%
3589974 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 46.0 4.00e-01 87.4% 70.3%
4955671 7089.1.1.0 ↗ a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD 0.57 42.0 4.48e-01 82.1% 93.8%
3633627 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.56 40.0 3.43e-01 72.6% 97.9%
3241305 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.56 44.0 3.97e-01 94.7% 58.6%
3427602 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.56 45.0 3.09e-01 85.3% 46.0%
3529940 292.2.1.11 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › C5orf34_2nd 0.56 40.0 4.02e-01 96.8% 72.9%
4890891 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.56 45.0 3.96e-01 87.4% 81.9%
3597379 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.56 46.0 4.37e-01 88.4% 80.0%
4373611 4237.1.1.1 ↗ beta barrels › FomD-like › FomD-like › FomD-like › DUF402 0.56 44.0 3.59e-01 83.2% 56.6%
1413889 274.1.1.5 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits › YadA_anchor 0.56 35.0 3.56e-01 81.1% 64.8%
3232743 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.55 48.0 3.58e-01 100.0% 37.6%
3228242 4210.1.1.1 ↗ a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.55 50.0 4.91e-01 98.9% 95.0%
5060431 2004.1.1.198 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.55 45.0 3.03e-01 98.9% 22.6%
4946505 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.54 35.0 4.04e-01 82.1% 90.0%
3423257 5.1.3.142 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_AT5G49610-like 0.54 43.0 2.93e-01 86.3% 67.5%
3069457 1053.1.1.0 ↗ beta barrels › Factor H-binding protein (fHbp) N-terminal beta-barrel domain › Factor H-binding protein (fHbp) N-terminal beta-barrel domain › Factor H-binding protein (fHbp) N-terminal beta-barrel domain 0.54 32.0 3.96e-01 75.8% 98.2%
5037296 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.54 47.0 3.32e-01 96.8% 74.7%
3479042 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.54 36.0 4.06e-01 94.7% 94.3%
2538921 5.1.2.8 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_43 0.53 44.0 3.15e-01 90.5% 70.3%
3734385 5.1.4.38 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › ANAPC1 0.53 44.0 2.86e-01 89.5% 61.2%
3741046 5.1.4.348 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR75_1st 0.53 47.0 3.07e-01 96.8% 71.6%
4964119 300.1.1.18 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › FilR1_middle 0.53 43.0 3.59e-01 87.4% 76.9%
3194822 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.52 46.0 2.96e-01 95.8% 83.6%
3225336 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.52 46.0 4.03e-01 98.9% 91.7%
3515545 304.107.1.7 ↗ a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › POP1_N+POPLD 0.52 46.0 3.04e-01 100.0% 82.1%
1813127 5.1.4.37 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup160 0.51 44.0 2.80e-01 96.8% 86.1%
3997324 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.51 45.0 3.81e-01 98.9% 96.9%
3692758 5.1.4.35 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Lactonase 0.50 42.0 2.77e-01 92.6% 72.5%
D2 high residues 88-134
PDB