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hypothetical_protein_pv_333
Euk-VirPithovirus_sibericum
hypothetical_protein_pv_333__YP_009001235__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001235 ↗
- Protein ID:
- hypothetical_protein_pv_333
- Kingdom:
- euk
Quality
63.9
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 210-261
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3bvoB01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.70 | 60.0 | 4.96e-01 | 100.0% | 66.3% |
| 4c0eA01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.66 | 56.0 | 3.55e-01 | 100.0% | 29.0% |
| 1bucA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.61 | 52.0 | 4.00e-01 | 100.0% | 48.0% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 50.0 | 4.00e-01 | 100.0% | 49.6% |
| 1khbA03 | 3.90.228.20 | Alpha Beta › Alpha-Beta Complex › Phosphoenolpyruvate Carboxykinase; domain 3 › | 0.60 | 50.0 | 3.25e-01 | 100.0% | 60.5% |
| 4rayA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.59 | 40.0 | 3.47e-01 | 71.2% | 70.6% |
| 2rp5A00 | 1.10.150.830 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.57 | 47.0 | 3.76e-01 | 98.1% | 65.8% |
| 4g84A01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.55 | 43.0 | 2.71e-01 | 94.2% | 38.4% |
| 2fe3B01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 43.0 | 3.75e-01 | 90.4% | 68.2% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 43.0 | 3.66e-01 | 88.5% | 82.2% |
| 2ix5A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.53 | 44.0 | 3.37e-01 | 98.1% | 39.6% |
| 7xhlD02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.52 | 44.0 | 2.76e-01 | 100.0% | 61.9% |
| 3h3aA04 | 1.10.246.80 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.50 | 34.0 | 3.47e-01 | 71.2% | 72.0% |
| 2da7A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.50 | 36.0 | 3.39e-01 | 100.0% | 60.6% |
| 3h7iA02 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.50 | 41.0 | 3.66e-01 | 94.2% | 85.7% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4030559 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.66 | 51.0 | 4.73e-01 | 92.3% | 91.9% |
| 3590851 | 181.2.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › CtsR dimerization domain › CtsR dimerization domain › CtsR_C | 0.59 | 40.0 | 3.43e-01 | 71.2% | 61.3% |
| 3935329 | 108.1.1.96 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 | 0.58 | 39.0 | 3.52e-01 | 71.2% | 68.0% |
| 3646179 | 4030.1.1.20 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › Ovate | 0.57 | 46.0 | 4.60e-01 | 100.0% | 98.2% |
| 3821011 | 145.1.1.1 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain › F-box | 0.55 | 40.0 | 4.02e-01 | 100.0% | 80.0% |
| 5009988 | 2002.1.1.83 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 | 0.52 | 42.0 | 2.66e-01 | 100.0% | 30.3% |
| 4954820 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.52 | 45.0 | 3.14e-01 | 100.0% | 69.7% |
| 4160299 | 3949.1.1.1 ↗ | alpha arrays › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › IPPT | 0.51 | 38.0 | 3.53e-01 | 78.8% | 84.6% |
D2
medium
residues 3-47
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2vzoA03 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.69 | 55.0 | 3.27e-01 | 88.9% | 50.7% |
| 3qktD01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 53.0 | 3.28e-01 | 100.0% | 16.4% |
| 1xdnA02 | 3.30.470.30 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme | 0.61 | 49.0 | 3.57e-01 | 100.0% | 32.9% |
| 2k49A00 | 2.30.29.80 | Mainly Beta › Roll › PH-domain like › | 0.61 | 50.0 | 3.74e-01 | 93.3% | 95.8% |
| 3gg6A00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.56 | 43.0 | 3.25e-01 | 97.8% | 89.6% |
| 2yztA00 | 3.30.160.250 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.55 | 46.0 | 4.16e-01 | 100.0% | 93.9% |
| 1ywyA00 | 3.40.1170.40 | Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › Protein of unknown function DUF3203 | 0.55 | 43.0 | 3.76e-01 | 93.3% | 58.1% |
| 5deqA01 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.54 | 39.0 | 3.01e-01 | 88.9% | 90.6% |
| 5h5oA00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.53 | 43.0 | 3.28e-01 | 100.0% | 95.2% |
| 2hoeA03 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.53 | 43.0 | 3.15e-01 | 100.0% | 34.5% |
| 2dk1A00 | 2.20.70.10 | Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › | 0.53 | 43.0 | 4.27e-01 | 100.0% | 90.0% |
| 1nnnA02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.52 | 41.0 | 3.13e-01 | 93.3% | 43.8% |
| 2yhwA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 42.0 | 2.99e-01 | 100.0% | 28.0% |
| 2a6aB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.51 | 40.0 | 3.17e-01 | 97.8% | 77.3% |
| 4kyxA00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.51 | 39.0 | 2.97e-01 | 93.3% | 96.4% |
| 4ktbA00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.51 | 37.0 | 2.77e-01 | 91.1% | 91.9% |
| 3uoxB01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.51 | 41.0 | 2.58e-01 | 100.0% | 49.8% |
| 1ultB01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.50 | 45.0 | 2.58e-01 | 100.0% | 52.7% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5064396 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.80 | 64.0 | 3.71e-01 | 86.7% | 11.8% |
| 5069317 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.79 | 60.0 | 3.46e-01 | 84.4% | 9.6% |
| 5036054 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.76 | 58.0 | 3.30e-01 | 84.4% | 8.9% |
| 4947567 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.76 | 58.0 | 3.29e-01 | 84.4% | 8.4% |
| 4320633 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.76 | 59.0 | 3.37e-01 | 86.7% | 9.2% |
| 5029795 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.75 | 58.0 | 3.41e-01 | 86.7% | 11.2% |
| 3273440 | 130.1.1.0 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif | 0.71 | 57.0 | 4.41e-01 | 91.1% | 99.0% |
| 5009920 | 2004.1.1.308 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 | 0.71 | 55.0 | 3.35e-01 | 91.1% | 13.7% |
| 4991403 | 2004.1.1.308 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 | 0.70 | 54.0 | 3.17e-01 | 84.4% | 12.2% |
| 3579473 | 209.1.1.1 ↗ | a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C | 0.69 | 54.0 | 4.12e-01 | 91.1% | 37.4% |
| 5073876 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.68 | 52.0 | 3.00e-01 | 91.1% | 9.6% |
| 3338669 | 64.1.1.1 ↗ | beta meanders › WW domain-like › WW domain › WW domain › WW | 0.67 | 48.0 | 4.55e-01 | 77.8% | 70.9% |
| 3244850 | 207.1.1.81 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH | 0.64 | 54.0 | 3.49e-01 | 97.8% | 20.9% |
| 5047148 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.63 | 49.0 | 3.07e-01 | 100.0% | 15.2% |
| 3716751 | 206.1.3.23 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase | 0.62 | 50.0 | 3.64e-01 | 100.0% | 31.6% |
| 1589113 | 3581.1.1.0 ↗ | a+b complex topology › E3 ubiquitin-protein ligase SopA catalytic domain › E3 ubiquitin-protein ligase SopA catalytic domain › E3 ubiquitin-protein ligase SopA catalytic domain | 0.62 | 49.0 | 2.82e-01 | 86.7% | 11.8% |
| 5074448 | 2003.1.2.300 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › GGR_cat | 0.61 | 43.0 | 2.54e-01 | 75.6% | 33.6% |
| 3213553 | 207.1.1.52 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FBA_2 | 0.60 | 49.0 | 3.13e-01 | 100.0% | 27.9% |
| 3874464 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.59 | 46.0 | 2.85e-01 | 97.8% | 60.3% |
| 4241225 | 304.102.1.6 ↗ | a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruB_N,TruB_C_2 | 0.58 | 47.0 | 2.96e-01 | 97.8% | 91.9% |
| 3419548 | 1.1.11.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 | 0.58 | 51.0 | 3.79e-01 | 97.8% | 56.4% |
| 4959079 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.58 | 45.0 | 2.59e-01 | 100.0% | 8.3% |
| 3240574 | 304.112.1.0 ↗ | a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain | 0.56 | 44.0 | 3.16e-01 | 100.0% | 40.6% |
| 4206222 | 4281.1.1.1 ↗ | a+b two layers › Ribosomal protein L35p › Ribosomal protein L35p › Ribosomal protein L35p › Ribosomal_L35p | 0.55 | 41.0 | 3.75e-01 | 88.9% | 83.8% |
| 4044503 | 4281.1.1.1 ↗ | a+b two layers › Ribosomal protein L35p › Ribosomal protein L35p › Ribosomal protein L35p › Ribosomal_L35p | 0.55 | 40.0 | 3.81e-01 | 86.7% | 93.3% |
| 3385533 | 212.1.1.12 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › UPF0029 | 0.53 | 44.0 | 3.19e-01 | 93.3% | 55.2% |
| 4974423 | 2003.1.2.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 | 0.52 | 39.0 | 2.33e-01 | 84.4% | 11.1% |
| 4943149 | 2003.1.2.300 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › GGR_cat | 0.51 | 35.0 | 2.18e-01 | 80.0% | 11.6% |
| 3179020 | 1.1.11.8 ↗ | beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › DUF6699 | 0.51 | 42.0 | 3.52e-01 | 95.6% | 81.2% |
| 3205603 | 221.1.1.211 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › DUF6699 | 0.50 | 42.0 | 3.58e-01 | 95.6% | 86.7% |
| 3970555 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.50 | 35.0 | 2.27e-01 | 77.8% | 15.3% |