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hypothetical_protein_pv_337

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_337__YP_009001239__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001239 ↗
Protein ID:
hypothetical_protein_pv_337
Kingdom:
euk

Quality

64.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 201-289
PDB
D2 medium residues 290-352
PDB
Domain cluster: representative
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3pubA01 1.10.10.2400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain 0.78 66.0 6.22e-01 92.1% 95.9%
2ouxA01 1.25.60.10 Mainly Alpha › Alpha Horseshoe › MgtE N-terminal fold › MgtE N-terminal domain-like 0.74 61.0 4.83e-01 90.5% 70.3%
3zheD01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 59.0 4.18e-01 100.0% 60.0%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 56.0 4.42e-01 88.9% 59.5%
6axfA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.67 60.0 4.87e-01 98.4% 84.6%
2ondA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 58.0 3.77e-01 100.0% 24.4%
2kj8A00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.66 45.0 3.75e-01 73.0% 89.8%
3ph0C00 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 49.0 5.26e-01 79.4% 100.0%
6z0fA02 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.63 54.0 3.99e-01 95.2% 54.2%
2ra1A02 1.20.58.780 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 49.0 4.75e-01 81.0% 100.0%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 47.0 4.73e-01 79.4% 98.4%
3vwaA03 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.63 53.0 3.50e-01 100.0% 34.6%
4fymF00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 53.0 3.65e-01 92.1% 90.9%
1dk5A02 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.62 50.0 4.85e-01 90.5% 100.0%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.62 47.0 4.29e-01 82.5% 85.9%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.62 45.0 3.61e-01 77.8% 57.1%
4gpkF02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 51.0 3.46e-01 92.1% 31.7%
6xy4A01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.61 49.0 4.04e-01 90.5% 61.0%
4u04B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 49.0 4.43e-01 88.9% 64.8%
3qdnA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 49.0 4.51e-01 88.9% 67.9%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 53.0 4.05e-01 96.8% 59.7%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.60 45.0 4.28e-01 81.0% 85.7%
2ho1B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 52.0 3.60e-01 96.8% 28.5%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.60 53.0 3.63e-01 100.0% 45.9%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 53.0 4.52e-01 98.4% 66.3%
2xevB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 53.0 4.26e-01 100.0% 63.7%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.60 46.0 4.19e-01 84.1% 84.7%
1ihgA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 52.0 4.00e-01 98.4% 59.3%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 51.0 3.90e-01 100.0% 58.9%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.59 40.0 3.26e-01 71.4% 96.2%
4gywA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 50.0 4.32e-01 100.0% 66.7%
4k51B00 1.25.40.860 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 44.0 3.40e-01 85.7% 62.9%
6lpfA01 1.10.730.20 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › 0.57 49.0 3.65e-01 95.2% 45.4%
2c2lA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 50.0 3.96e-01 98.4% 52.6%
3bqoA00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.57 47.0 3.43e-01 98.4% 40.6%
3dzaA01 1.20.120.1940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain 0.57 44.0 3.59e-01 84.1% 85.5%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 48.0 4.61e-01 96.8% 93.3%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.55 42.0 3.72e-01 88.9% 76.7%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 44.0 4.19e-01 87.3% 85.3%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 44.0 3.86e-01 87.3% 81.7%
1n00A03 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.54 41.0 4.02e-01 92.1% 100.0%
3zevB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 40.0 2.62e-01 81.0% 75.0%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.51 42.0 3.72e-01 90.5% 72.0%
2yxhA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.51 46.0 3.79e-01 100.0% 64.6%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3414736 109.4.1.393 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS1_RP2B-bd 0.75 66.0 4.09e-01 100.0% 43.9%
3387891 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 64.0 3.65e-01 98.4% 12.8%
4383896 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 55.0 4.21e-01 90.5% 40.0%
4058784 109.4.1.1457 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27772 0.67 57.0 3.76e-01 93.7% 32.2%
3438208 109.4.1.1285 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, Eplus_motif, E_motif 0.64 56.0 3.13e-01 100.0% 8.7%
3317104 4030.1.1.0 ↗ alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.64 43.0 4.33e-01 71.4% 78.5%
3231182 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 56.0 3.19e-01 100.0% 18.2%
3459519 2003.1.5.31 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS 0.63 45.0 3.28e-01 76.2% 35.7%
4019540 109.4.1.862 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ZW10_C2 0.63 53.0 3.11e-01 100.0% 26.5%
3192973 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 51.0 3.45e-01 93.7% 66.9%
5029773 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.63 47.0 4.50e-01 81.0% 86.5%
3627886 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 53.0 3.43e-01 100.0% 27.9%
5065296 604.17.1.0 ↗ alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like 0.62 46.0 4.69e-01 77.8% 100.0%
3704286 604.12.1.8 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT 0.62 47.0 3.98e-01 81.0% 67.0%
3812592 109.4.1.1948 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle 0.61 51.0 3.77e-01 90.5% 70.0%
3168793 109.4.1.339 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRAPPC-Trs85 0.61 50.0 3.13e-01 90.5% 80.5%
4933309 604.17.1.0 ↗ alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like 0.61 47.0 4.85e-01 82.5% 100.0%
3670337 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 48.0 4.26e-01 88.9% 87.8%
3639366 109.4.1.1978 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_2, ANAPC3, TPR_8, TPR_16, PF29407 0.59 52.0 3.29e-01 100.0% 22.0%
4983683 604.12.1.140 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF447_C 0.59 44.0 4.44e-01 81.0% 95.4%
3507780 604.12.1.8 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT 0.58 46.0 4.13e-01 84.1% 80.0%
3472751 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 47.0 3.04e-01 93.7% 43.1%
4999221 109.4.1.198 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.58 50.0 3.32e-01 98.4% 31.5%
3773235 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.58 45.0 3.99e-01 84.1% 74.4%
4999613 109.4.1.5 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.58 51.0 3.17e-01 100.0% 18.5%
3883622 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.58 45.0 4.25e-01 84.1% 89.3%
4958881 109.4.1.198 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.58 49.0 3.65e-01 96.8% 48.8%
5000553 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.57 43.0 4.17e-01 81.0% 92.9%
3931593 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.57 46.0 4.28e-01 88.9% 85.0%
3940014 109.27.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain 0.57 44.0 4.71e-01 90.5% 100.0%
3649945 604.12.1.70 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › FIGL1_N 0.56 49.0 4.23e-01 95.2% 94.7%
4929706 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.56 44.0 4.26e-01 84.1% 95.7%
3252144 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 43.0 4.23e-01 84.1% 95.7%
4933335 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.56 44.0 4.10e-01 84.1% 83.7%
3594772 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 44.0 4.04e-01 85.7% 81.2%
3270441 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.56 44.0 4.19e-01 85.7% 90.7%
3699282 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.56 44.0 4.01e-01 85.7% 81.2%
3481781 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.55 44.0 4.07e-01 85.7% 86.3%
5076876 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.55 43.0 3.99e-01 84.1% 77.5%
3497029 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 43.0 3.74e-01 85.7% 69.0%
3418094 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.55 44.0 4.11e-01 87.3% 80.0%
3168021 604.12.1.2 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.55 43.0 4.04e-01 87.3% 76.2%
165995 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.55 44.0 4.19e-01 87.3% 85.3%
3879426 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.55 42.0 3.89e-01 84.1% 80.7%
3790404 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 46.0 3.35e-01 98.4% 45.6%
4978312 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.55 44.0 4.28e-01 87.3% 91.4%
5032368 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 43.0 4.28e-01 85.7% 98.5%
3558834 604.12.1.6 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › NRBF2_MIT 0.54 43.0 3.81e-01 85.7% 75.6%
3480252 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.54 43.0 4.05e-01 85.7% 94.7%
3267491 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.54 44.0 4.29e-01 90.5% 94.3%
3226337 109.54.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 0.53 43.0 2.63e-01 98.4% 88.8%
3743018 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.53 43.0 4.28e-01 87.3% 98.5%
3581466 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.53 45.0 4.20e-01 95.2% 95.0%
3267859 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.53 44.0 3.90e-01 90.5% 68.9%
3402139 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.53 43.0 3.94e-01 90.5% 77.6%
3225484 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.53 44.0 4.24e-01 90.5% 94.3%
4999686 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.53 43.0 4.11e-01 90.5% 88.0%
2393375 633.16.1.1 ↗ alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like › MLD 0.52 38.0 3.60e-01 82.5% 73.8%
4947260 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.51 44.0 4.08e-01 95.2% 97.5%