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hypothetical_protein_pv_353

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_353__YP_009001255__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001255 ↗
Protein ID:
hypothetical_protein_pv_353
Kingdom:
euk

Quality

70.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-114
PDB
D2 medium residues 115-223
PDB
Domain cluster: representative
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3deoA02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.71 63.0 5.74e-01 97.2% 80.8%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.69 47.0 4.45e-01 70.6% 76.9%
5h28A02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.68 59.0 5.91e-01 94.5% 100.0%
4leuA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 58.0 4.85e-01 99.1% 56.0%
5dikA00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.67 49.0 4.91e-01 81.7% 75.0%
3zpjA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 55.0 3.87e-01 96.3% 34.0%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.63 44.0 4.90e-01 91.7% 95.2%
2gomA00 1.10.10.1270 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV 0.62 32.0 4.17e-01 84.4% 90.2%
4uurA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 46.0 4.47e-01 94.5% 70.2%
4me2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 52.0 4.35e-01 97.2% 68.6%
5gj7A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.60 41.0 3.96e-01 70.6% 71.2%
6t0bf00 1.25.40.40 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI 0.59 49.0 5.03e-01 93.6% 97.1%
3ciaA04 1.25.40.320 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain 0.58 51.0 4.71e-01 99.1% 91.4%
4ui9Y03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 39.0 4.44e-01 93.6% 100.0%
7zcvA02 1.25.40.400 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 48.0 3.94e-01 97.2% 57.1%
2ooeA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 47.0 3.93e-01 99.1% 53.2%
3ajfA00 1.20.1440.190 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tenuivirus movement protein 0.55 35.0 3.81e-01 85.3% 76.1%
3fp3A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 44.0 4.17e-01 100.0% 71.1%
4eadA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.55 45.0 4.54e-01 90.8% 91.6%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.55 38.0 3.98e-01 72.5% 78.8%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 35.0 3.84e-01 93.6% 78.9%
2af7D00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.54 48.0 4.71e-01 99.1% 96.7%
2gmyD00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.53 35.0 3.28e-01 72.5% 50.3%
2kckA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 44.0 4.37e-01 97.2% 88.4%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 43.0 3.62e-01 89.9% 80.6%
4rg9B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 43.0 3.78e-01 94.5% 58.7%
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 46.0 3.59e-01 100.0% 68.1%
2vixA03 1.20.1280.240 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.53 42.0 4.24e-01 88.1% 87.6%
2qeuB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.52 47.0 4.42e-01 100.0% 88.7%
6hftA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 43.0 4.17e-01 98.2% 80.3%
3mkqB00 1.25.40.470 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 40.0 3.43e-01 100.0% 50.3%
2ygwA01 1.20.140.90 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain 0.52 42.0 3.82e-01 90.8% 95.4%
4a2qA01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.51 30.0 3.21e-01 90.8% 65.6%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 39.0 3.56e-01 93.6% 60.4%
3ceqA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 44.0 3.46e-01 100.0% 50.0%
2mhkA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 39.0 3.81e-01 85.3% 93.6%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3271428 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.71 65.0 4.66e-01 100.0% 39.7%
3268163 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 63.0 5.66e-01 98.2% 95.3%
3223295 109.4.1.1329 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NatB_MDM20, PF31234 0.70 62.0 3.75e-01 99.1% 20.1%
4119298 109.4.1.923 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › AEP1 0.70 63.0 4.26e-01 98.2% 32.1%
3724275 109.3.1.96 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.69 62.0 3.98e-01 100.0% 30.8%
3426175 109.4.1.1308 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, TPR_24 0.69 62.0 3.92e-01 100.0% 19.3%
3312004 109.4.1.1257 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 0.66 54.0 5.02e-01 97.2% 69.3%
3834553 109.4.1.1271 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 0.66 58.0 4.64e-01 97.2% 52.6%
5078543 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.66 58.0 5.33e-01 100.0% 82.8%
3421753 226.1.1.1 a+b two layers › POZ domain › POZ domain › POZ domain › BTB 0.65 47.0 4.19e-01 91.7% 51.9%
3863016 109.4.1.1329 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NatB_MDM20, PF31234 0.65 58.0 3.41e-01 100.0% 16.5%
3645652 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 57.0 4.77e-01 97.2% 63.7%
4458484 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.64 56.0 5.20e-01 100.0% 77.0%
3367887 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 51.0 5.02e-01 100.0% 80.8%
3314808 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 57.0 5.12e-01 100.0% 78.7%
3336338 109.4.1.1330 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_3, PPR_long 0.63 52.0 4.87e-01 97.2% 73.3%
3595433 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 54.0 4.56e-01 98.2% 57.9%
3457006 109.4.1.1305 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long, TPR_24 0.62 54.0 4.21e-01 100.0% 43.3%
3422238 226.1.1.0 a+b two layers › POZ domain › POZ domain › POZ domain 0.62 46.0 4.26e-01 91.7% 60.0%
3424708 109.4.1.1269 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, E_motif 0.61 50.0 4.61e-01 99.1% 70.0%
3702423 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 52.0 3.74e-01 98.2% 32.4%
3480178 2007.15.1.11 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › MAP3K_TRAF_bd 0.60 50.0 4.42e-01 92.7% 75.2%
3421464 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 52.0 4.25e-01 99.1% 54.9%
3789793 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 3.06e-01 99.1% 13.1%
3729157 109.4.1.2512 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT, TPR_19, HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N, HAT_PRP39_N, HAT_PRP39_C 0.59 51.0 3.20e-01 100.0% 16.2%
3683298 109.4.1.68 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Coatomer_E 0.59 46.0 3.42e-01 85.3% 50.5%
3226310 109.4.1.68 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Coatomer_E 0.59 46.0 3.46e-01 84.4% 53.6%
3609415 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 52.0 3.83e-01 100.0% 84.3%
3725437 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 42.0 4.26e-01 76.1% 100.0%
3837456 109.4.1.12 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Clathrin 0.58 52.0 4.17e-01 99.1% 53.5%
3735101 109.3.1.8 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.57 50.0 4.52e-01 96.3% 93.3%
3493630 109.4.1.1142 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_IFT80_172 0.57 43.0 3.31e-01 79.8% 38.8%
3738962 109.4.1.1329 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NatB_MDM20, PF31234 0.57 45.0 3.58e-01 96.3% 41.8%
3190533 109.4.1.3564 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_CNRKL1_C, HAT_PRP39_N, HAT_PRP39_C 0.56 49.0 3.28e-01 100.0% 22.5%
3702902 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 44.0 4.21e-01 82.6% 100.0%
3822048 109.4.1.83 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf 0.56 49.0 3.13e-01 100.0% 19.1%
3686175 109.4.1.1757 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT, HAT_PRP39_C 0.56 48.0 4.08e-01 97.2% 62.1%
143057 3825.1.1.1 alpha arrays › Non-structural protein 3 › Non-structural protein 3 › Non-structural protein 3 › Tenui_NS3 0.55 35.0 3.81e-01 85.3% 76.1%
None 0.54 48.0 3.47e-01 99.1% 33.4%
3603394 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 43.0 4.53e-01 94.5% 96.0%
3709644 109.4.1.1390 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF31234 0.54 45.0 3.72e-01 91.7% 71.5%
3476811 109.4.1.1159 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_IFT122 0.53 44.0 3.24e-01 89.9% 33.8%
1406531 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 42.0 4.01e-01 98.2% 71.6%
3278128 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 46.0 4.27e-01 100.0% 89.0%
4996547 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 42.0 3.73e-01 85.3% 78.7%
5027336 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.52 43.0 3.44e-01 99.1% 44.4%
D3 medium residues 417-470
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5mi7A03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.73 66.0 4.13e-01 100.0% 37.5%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.73 65.0 4.47e-01 100.0% 55.0%
2qk1A01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.71 53.0 3.46e-01 98.1% 18.4%
1yy7A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.71 61.0 4.97e-01 100.0% 56.2%
3ppuB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.69 59.0 4.74e-01 100.0% 49.6%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.63 54.0 3.75e-01 96.3% 74.9%
3ix7A00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.63 43.0 3.25e-01 90.7% 29.0%
3geeA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.62 53.0 3.84e-01 100.0% 63.7%
4mo7A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 48.0 3.62e-01 96.3% 47.2%
2w3cA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.55 44.0 2.94e-01 100.0% 19.6%
3tw8A03 6.10.140.1000 Special › Helix non-globular › Helix Hairpins › 0.55 35.0 3.94e-01 85.2% 87.8%
4htpB00 1.10.3260.10 Mainly Alpha › Orthogonal Bundle › DNA ligase i, domain 1 › DNA ligase, ATP-dependent, N-terminal domain 0.54 44.0 3.03e-01 98.1% 23.4%
2psmA00 1.20.1250.70 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 0.52 42.0 3.37e-01 92.6% 84.6%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3735292 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.77 54.0 3.25e-01 75.9% 11.9%
3321734 633.1.1.0 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.71 48.0 3.72e-01 72.2% 33.0%
3481620 622.4.1.27 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › TB2_DP1_HVA22 0.71 54.0 4.61e-01 81.5% 51.8%
3616629 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.69 59.0 3.82e-01 98.1% 57.3%
4324738 160.1.1.1 alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_ab_C 0.66 47.0 3.32e-01 79.6% 24.8%
3597239 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 55.0 3.41e-01 100.0% 19.4%
3915138 109.4.1.901 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_GCN1 0.63 46.0 2.64e-01 100.0% 6.9%
3603633 3997.1.1.1 alpha arrays › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › CobN-Mg_chel 0.63 54.0 3.70e-01 96.3% 33.7%
4946322 2004.5.1.0 a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain 0.62 52.0 3.80e-01 96.3% 39.2%