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hypothetical_protein_pv_355

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_355__YP_009001257__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001257 ↗
Protein ID:
hypothetical_protein_pv_355
Kingdom:
euk

Quality

73.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (39 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-135
PDB
Domain cluster: rep: hypothetical_protein_pv_69__YP_009000971__Pithovirus_sibericum__1450746__D3-123
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF12937.13 best F-box-like 27.8 2.40e-06 33.3% 87.2%
PF00646.39 F-box 27.8 2.40e-06 30.4% 83.7%
D2 medium residues 276-376
PDB
Domain cluster: rep: hypothetical_protein_pv_359__YP_009001261__Pithovirus_sibericum__1450746__D233-333
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3b7bB00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.70 63.0 4.87e-01 99.0% 61.2%
4rlyA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.70 62.0 4.38e-01 97.0% 48.4%
3uxgA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.70 63.0 5.38e-01 99.0% 65.0%
1wdyA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.70 64.0 4.57e-01 100.0% 51.2%
5z2mB00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.70 61.0 5.54e-01 96.0% 81.0%
6ghmC01 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.70 64.0 5.78e-01 100.0% 79.1%
4uucA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.70 61.0 4.72e-01 96.0% 58.8%
1n11A00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.69 62.0 4.10e-01 98.0% 38.9%
3twqA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.69 61.0 5.13e-01 96.0% 64.0%
3utmA02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.68 60.0 5.50e-01 96.0% 75.6%
2zgdA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.68 51.0 5.23e-01 78.2% 82.5%
1iknD00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.67 59.0 4.60e-01 96.0% 65.1%
1s70B02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.67 59.0 5.46e-01 96.0% 80.6%
7xceA01 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.67 60.0 4.54e-01 99.0% 55.7%
3deoA02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.67 60.0 5.29e-01 99.0% 80.1%
4besA02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.66 58.0 5.30e-01 96.0% 88.0%
5aarA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.65 58.0 4.77e-01 98.0% 55.7%
8gpsA01 1.25.60.10 Mainly Alpha › Alpha Horseshoe › MgtE N-terminal fold › MgtE N-terminal domain-like 0.64 52.0 5.16e-01 94.1% 84.8%
4leuA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 53.0 4.46e-01 96.0% 54.4%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 42.0 4.10e-01 71.3% 95.5%
4n5cD06 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 46.0 4.44e-01 85.1% 81.4%
4f3vB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 47.0 3.57e-01 100.0% 38.6%
1bbhA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.55 39.0 3.64e-01 76.2% 100.0%
1e7uA05 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.54 40.0 3.25e-01 78.2% 70.2%
3beyD00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.53 39.0 4.04e-01 99.0% 84.0%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.52 45.0 3.99e-01 100.0% 66.2%
3up8A00 3.20.20.100 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain 0.51 45.0 3.30e-01 100.0% 55.5%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3203926 109.3.1.164 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3, Ank_4 0.74 65.0 4.56e-01 96.0% 32.6%
3372242 109.3.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.72 64.0 5.65e-01 97.0% 73.1%
3185936 109.3.1.20 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_4 0.71 65.0 5.37e-01 99.0% 80.0%
3342441 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.70 62.0 4.59e-01 96.0% 40.8%
3225017 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.70 58.0 5.04e-01 90.1% 59.3%
3886094 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.69 62.0 4.66e-01 96.0% 45.2%
3724275 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.69 63.0 3.98e-01 100.0% 29.2%
3249961 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.69 61.0 4.77e-01 96.0% 48.6%
4999694 109.3.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.68 60.0 4.44e-01 96.0% 51.8%
3893302 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.68 57.0 5.10e-01 90.1% 79.3%
3821942 109.3.1.169 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2, Ank_4, Ank_5 0.68 61.0 3.96e-01 100.0% 35.7%
4125096 109.3.1.96 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.67 59.0 4.27e-01 96.0% 47.6%
3933426 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 47.0 4.83e-01 73.3% 82.1%
3522805 109.3.1.162 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_5 0.66 59.0 4.85e-01 100.0% 61.1%
3990878 109.4.1.442 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › THOC2_N 0.59 50.0 4.15e-01 96.0% 57.4%
3562699 3736.1.1.0 ↗ alpha superhelices › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 0.58 47.0 4.46e-01 88.1% 100.0%
3683682 109.4.1.1280 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_long 0.58 51.0 4.08e-01 99.0% 65.7%
3384518 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.58 50.0 4.46e-01 99.0% 84.7%
3885902 3736.1.1.1 ↗ alpha superhelices › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 › NLRC4_HD2 0.58 43.0 3.98e-01 82.2% 94.3%
3287311 109.4.1.2330 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF31120 0.52 40.0 4.00e-01 84.2% 87.6%
D3 medium residues 377-511
PDB
Domain cluster: rep: hypothetical_protein_pv_362__YP_009001264__Pithovirus_sibericum__1450746__D417-540
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4g3aB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.62 56.0 4.68e-01 100.0% 70.9%
1iygA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 41.0 4.15e-01 85.2% 68.4%
3dadA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 52.0 3.94e-01 96.3% 62.3%
6i57A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 39.0 4.04e-01 87.4% 72.8%
1tjcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 39.0 4.40e-01 85.2% 96.8%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.57 39.0 4.31e-01 70.4% 98.2%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.57 45.0 4.40e-01 85.9% 99.3%
4bwrA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 48.0 3.36e-01 94.1% 32.5%
3sz7A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 38.0 3.75e-01 87.4% 62.3%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 45.0 4.51e-01 88.9% 89.3%
2gfnA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 41.0 3.69e-01 76.3% 86.5%
4b94A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 49.0 4.88e-01 100.0% 93.6%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 42.0 3.76e-01 83.0% 80.1%
4yvoA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 41.0 4.33e-01 87.4% 92.4%
3fflA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 40.0 4.18e-01 87.4% 85.7%
2e2eA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 39.0 3.77e-01 88.1% 67.5%
4g1tA03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 46.0 3.79e-01 94.1% 64.9%
1xnfA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 47.0 3.80e-01 97.8% 57.1%
3fp3A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 40.0 4.02e-01 97.0% 80.0%
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.52 34.0 3.97e-01 83.0% 98.9%
3p5nA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.52 40.0 3.80e-01 83.7% 95.2%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3600473 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 59.0 4.34e-01 100.0% 81.9%
3166518 109.4.1.307 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tho2 0.63 57.0 3.89e-01 100.0% 59.4%
3933570 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 40.0 4.52e-01 88.9% 86.0%
3844117 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 44.0 4.93e-01 90.4% 97.0%
4311303 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 52.0 5.01e-01 89.6% 99.3%
3908884 109.4.1.926 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FH3_FHOD1-3 0.59 53.0 4.36e-01 100.0% 79.6%
3453507 109.4.1.1254 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.59 48.0 4.03e-01 94.1% 50.9%
3718534 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 53.0 4.04e-01 100.0% 53.8%
3782403 109.4.1.888 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_CNRKL1_N 0.59 53.0 4.49e-01 100.0% 60.0%
3421745 109.4.1.1269 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, E_motif 0.59 45.0 3.75e-01 90.4% 44.9%
4000581 109.4.1.359 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.57 49.0 3.74e-01 92.6% 58.4%
3605579 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 49.0 3.93e-01 100.0% 57.5%
5052135 604.39.1.0 ↗ alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.54 43.0 3.85e-01 85.2% 94.2%
3380776 109.46.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) 0.53 41.0 3.68e-01 100.0% 56.5%
3503763 131.1.1.0 ↗ alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like 0.53 46.0 4.02e-01 97.0% 99.0%
None — 0.53 41.0 3.65e-01 100.0% 56.5%
None — 0.52 39.0 3.58e-01 79.3% 62.8%
4027803 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 44.0 3.50e-01 97.0% 66.0%