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hypothetical_protein_pv_392
Euk-VirPithovirus_sibericum
hypothetical_protein_pv_392__YP_009001293__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001293 ↗
- Protein ID:
- hypothetical_protein_pv_392
- Kingdom:
- euk
Quality
69.3
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 15-92
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2dy1A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 51.0 | 3.58e-01 | 92.3% | 93.1% |
| 4qa8A00 | 2.50.20.20 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › | 0.62 | 43.0 | 3.21e-01 | 73.1% | 90.0% |
| 5gaeG01 | 3.90.930.12 | Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 | 0.61 | 45.0 | 4.48e-01 | 79.5% | 95.1% |
| 2wdtC02 | 3.30.1490.420 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ubiquitin carboxyl-terminal hydrolase, domain 2 | 0.59 | 45.0 | 4.21e-01 | 83.3% | 83.2% |
| 5mmiG01 | 3.90.930.12 | Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 | 0.59 | 45.0 | 4.42e-01 | 82.1% | 95.2% |
| 1z1bA01 | 3.30.160.60 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger | 0.58 | 37.0 | 4.13e-01 | 92.3% | 87.7% |
| 3buuB00 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.57 | 44.0 | 3.28e-01 | 87.2% | 85.0% |
| 1vpkA02 | 3.10.150.10 | Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 | 0.55 | 37.0 | 3.19e-01 | 70.5% | 64.8% |
| 2l33A00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.55 | 43.0 | 4.10e-01 | 85.9% | 81.3% |
| 3ak5D02 | 2.160.20.20 | Mainly Beta › 3 Solenoid › Pectate Lyase C-like › | 0.54 | 40.0 | 2.35e-01 | 79.5% | 23.6% |
| 4bndA01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.54 | 41.0 | 3.36e-01 | 83.3% | 70.5% |
| 2dmyA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.54 | 46.0 | 4.36e-01 | 100.0% | 81.4% |
| 2ywlA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.53 | 43.0 | 3.43e-01 | 91.0% | 77.9% |
| 2ltrA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.53 | 40.0 | 3.68e-01 | 84.6% | 82.9% |
| 1sjiA01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.52 | 41.0 | 3.62e-01 | 88.5% | 58.1% |
| 7qi3A01 | 3.30.2140.20 | Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › | 0.52 | 43.0 | 2.92e-01 | 93.6% | 78.9% |
| 6hgcA01 | 3.40.532.10 | Alpha Beta › 3-Layer(aba) Sandwich › Ubiquitin C-terminal Hydrolase UCH-l3 › Peptidase C12, ubiquitin carboxyl-terminal hydrolase | 0.51 | 44.0 | 3.39e-01 | 100.0% | 40.3% |
| 1bjxA00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.51 | 40.0 | 3.65e-01 | 88.5% | 61.8% |
| 1u6gC00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 36.0 | 2.00e-01 | 74.4% | 10.1% |
| 2dixA01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.51 | 36.0 | 3.68e-01 | 76.9% | 88.5% |
| 4gqzA00 | 2.60.40.3700 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 39.0 | 3.12e-01 | 83.3% | 75.0% |
| 2vvlG01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.50 | 40.0 | 2.91e-01 | 91.0% | 97.3% |
| 3u9sE04 | 3.30.700.40 | Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › | 0.50 | 38.0 | 3.30e-01 | 82.1% | 70.4% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4558923 | 865.1.1.2 ↗ | beta complex topology › PheT/TilS domain › PheT/TilS domain › PheT/TilS domain › TilS_C | 0.61 | 42.0 | 3.82e-01 | 71.8% | 98.1% |
| 4538202 | 2004.1.1.17 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head | 0.60 | 45.0 | 2.66e-01 | 82.1% | 80.4% |
| 3595003 | 3115.1.1.0 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like | 0.59 | 32.0 | 3.54e-01 | 98.7% | 66.7% |
| 3293107 | 4286.1.1.1 ↗ | beta complex topology › At5g01610-like › At5g01610-like › At5g01610-like › DUF538 | 0.57 | 46.0 | 3.94e-01 | 87.2% | 99.2% |
| 3499134 | 2485.1.1.1 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin | 0.56 | 47.0 | 3.94e-01 | 93.6% | 59.3% |
| 3603731 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.56 | 43.0 | 3.59e-01 | 83.3% | 69.3% |
| 4951132 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 44.0 | 3.32e-01 | 88.5% | 40.0% |
| 4953866 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.56 | 42.0 | 3.17e-01 | 83.3% | 82.3% |
| 5035585 | 2003.1.1.22 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA | 0.55 | 43.0 | 3.39e-01 | 89.7% | 86.3% |
| 3225057 | 207.1.1.81 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH | 0.54 | 40.0 | 3.04e-01 | 78.2% | 45.4% |
| 4082601 | 2004.1.1.414 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU, MMR_HSR1 | 0.54 | 45.0 | 3.22e-01 | 96.2% | 94.7% |
| 4958164 | 298.1.1.42 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA | 0.54 | 43.0 | 3.03e-01 | 92.3% | 87.5% |
| 134360 | 252.2.1.3 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_1 | 0.54 | 34.0 | 3.73e-01 | 92.3% | 79.7% |
| 3430385 | 4099.1.1.1 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › MAD | 0.54 | 39.0 | 3.38e-01 | 78.2% | 73.6% |
| 4411707 | 298.1.1.24 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 | 0.53 | 36.0 | 2.51e-01 | 70.5% | 80.4% |
| 3226804 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.52 | 42.0 | 3.82e-01 | 88.5% | 67.6% |
| 3374406 | 2485.1.1.1 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin | 0.52 | 46.0 | 3.81e-01 | 100.0% | 55.7% |
| 3215907 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 38.0 | 2.68e-01 | 78.2% | 37.8% |
| 380523 | 219.1.1.9 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C12 | 0.51 | 44.0 | 3.31e-01 | 97.4% | 38.3% |
| 3781869 | 2485.1.1.1 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin | 0.51 | 44.0 | 3.66e-01 | 97.4% | 70.0% |
| 3684591 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.51 | 39.0 | 3.83e-01 | 98.7% | 76.5% |
| 5059169 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.51 | 41.0 | 3.46e-01 | 91.0% | 82.9% |
| 4989457 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.51 | 32.0 | 3.84e-01 | 79.5% | 100.0% |
D2
high
residues 110-196_226-235
Domain cluster:
rep: hypothetical_protein_MEL_353__YP_009094854__Melbournevirus__1560514__D107-191
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1z1bA01 | 3.30.160.60 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger | 0.67 | 28.0 | 3.55e-01 | 74.2% | 63.2% |
| 2e5vA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.59 | 41.0 | 3.00e-01 | 72.2% | 77.4% |
| 5efrA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.57 | 28.0 | 3.15e-01 | 70.1% | 60.3% |
| 8d3mA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.54 | 44.0 | 3.38e-01 | 90.7% | 68.8% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 39.0 | 2.85e-01 | 75.3% | 36.9% |
| 4q5eA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.54 | 37.0 | 3.79e-01 | 76.3% | 74.2% |
| 2oap202 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 42.0 | 3.07e-01 | 88.7% | 97.5% |
| 2q07A02 | 3.10.450.90 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › ArcTGT, C2 domain | 0.52 | 34.0 | 3.93e-01 | 74.2% | 100.0% |
| 2hoxA03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.50 | 35.0 | 3.39e-01 | 73.2% | 99.1% |
| 4rsuE01 | 2.10.50.10 | Mainly Beta › Ribbon › Tumor Necrosis Factor Receptor, subunit A; domain 2 › Tumor Necrosis Factor Receptor, subunit A, domain 2 | 0.50 | 25.0 | 3.01e-01 | 75.3% | 72.9% |
| 6hwjA01 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.50 | 41.0 | 3.13e-01 | 89.7% | 86.3% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4993163 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.63 | 36.0 | 2.38e-01 | 78.4% | 13.3% |
| None | — | 0.57 | 42.0 | 2.95e-01 | 78.4% | 76.0% | |
| 3991165 | 389.1.1.28 ↗ | few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › cEGF | 0.56 | 22.0 | 3.04e-01 | 70.1% | 68.9% |
| 4984579 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.55 | 42.0 | 2.72e-01 | 81.4% | 71.3% |
| 5029609 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.54 | 37.0 | 2.41e-01 | 70.1% | 80.5% |
| 3542657 | 2007.1.2.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor | 0.53 | 37.0 | 3.02e-01 | 72.2% | 100.0% |
| 3913735 | 2007.1.2.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor | 0.52 | 36.0 | 3.01e-01 | 72.2% | 100.0% |
| 3739312 | 7516.1.1.7 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › UDPGP | 0.52 | 46.0 | 2.99e-01 | 100.0% | 68.0% |
| 4026623 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.52 | 42.0 | 3.36e-01 | 89.7% | 96.6% |
| 4947063 | 325.1.8.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Ribosomal L27 protein | 0.52 | 24.0 | 3.18e-01 | 72.2% | 84.0% |
| 3436868 | 325.1.8.2 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Ribosomal L27 protein › ECR1_N | 0.51 | 26.0 | 3.34e-01 | 76.3% | 94.0% |