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hypothetical_protein_pv_439

Euk-Vir

Pithovirus_sibericum

hypothetical_protein_pv_439__YP_009001340__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001340 ↗
Protein ID:
hypothetical_protein_pv_439
Kingdom:
euk

Quality

69.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-101
PDB
Domain cluster: representative
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.74 55.0 5.31e-01 83.2% 69.6%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.73 59.0 6.14e-01 86.1% 95.7%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.70 50.0 4.40e-01 75.2% 54.3%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.70 48.0 3.77e-01 70.3% 35.6%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.69 54.0 4.85e-01 84.2% 61.0%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 54.0 5.28e-01 85.1% 81.5%
1kz7A01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.67 47.0 3.81e-01 72.3% 81.3%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.67 44.0 4.46e-01 76.2% 67.0%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 54.0 5.38e-01 87.1% 99.0%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.66 45.0 4.14e-01 70.3% 88.7%
3pivA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.66 50.0 4.35e-01 81.2% 84.0%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 41.0 4.77e-01 73.3% 88.9%
2gfpA00 1.20.1720.10 Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D 0.65 53.0 3.51e-01 86.1% 38.9%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 45.0 4.53e-01 79.2% 88.3%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 46.0 4.50e-01 82.2% 89.3%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.60 48.0 4.73e-01 86.1% 91.5%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.60 37.0 3.79e-01 88.1% 64.6%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 48.0 4.06e-01 87.1% 76.3%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.59 43.0 4.31e-01 96.0% 72.6%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.59 50.0 4.44e-01 95.0% 92.8%
4x28A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.59 42.0 4.07e-01 73.3% 65.5%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 44.0 3.73e-01 79.2% 90.8%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 49.0 4.58e-01 91.1% 86.7%
7dl9A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.59 47.0 3.80e-01 85.1% 79.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.58 40.0 4.26e-01 71.3% 82.8%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 43.0 3.81e-01 79.2% 78.0%
1ui6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 52.0 4.22e-01 100.0% 65.1%
3s6jE02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.57 33.0 3.95e-01 77.2% 85.5%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.56 47.0 4.48e-01 90.1% 99.1%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.56 47.0 4.61e-01 90.1% 95.4%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 3.97e-01 79.2% 74.2%
1h2tC03 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 48.0 3.67e-01 96.0% 47.5%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.56 40.0 4.13e-01 91.1% 80.6%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 49.0 4.38e-01 99.0% 99.3%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.55 36.0 3.78e-01 88.1% 72.5%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 43.0 3.76e-01 83.2% 81.2%
5xdcB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.55 38.0 3.74e-01 72.3% 65.8%
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 35.0 3.82e-01 73.3% 78.6%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 41.0 3.83e-01 81.2% 89.2%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 48.0 3.76e-01 100.0% 56.8%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 41.0 3.65e-01 83.2% 80.9%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.53 40.0 4.20e-01 95.0% 90.0%
1by1A00 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.52 42.0 3.48e-01 93.1% 75.6%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 4.05e-01 76.2% 90.6%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.51 42.0 3.70e-01 91.1% 61.3%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 40.0 3.97e-01 86.1% 90.9%
1txdA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.51 43.0 3.41e-01 97.0% 70.6%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3834034 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.77 57.0 4.79e-01 79.2% 47.3%
4430478 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.76 58.0 4.51e-01 80.2% 76.7%
5083369 604.4.1.0 alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP 0.76 61.0 6.36e-01 85.1% 96.8%
5029480 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.72 60.0 4.72e-01 90.1% 79.3%
4565834 106.1.1.11 alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N 0.72 59.0 5.18e-01 89.1% 66.0%
4571267 1079.1.1.13 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp 0.71 56.0 4.67e-01 85.1% 84.8%
4600613 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.71 51.0 4.66e-01 78.2% 57.7%
4080313 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.71 52.0 4.68e-01 77.2% 75.0%
5029677 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.70 58.0 4.04e-01 89.1% 46.7%
5082892 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.69 57.0 4.84e-01 90.1% 57.6%
4986380 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.67 56.0 4.49e-01 92.1% 79.5%
134276 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.67 44.0 4.46e-01 76.2% 67.0%
3258488 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 45.0 4.61e-01 70.3% 92.0%
4247625 7022.1.1.1 alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › MBOAT 0.65 56.0 3.86e-01 96.0% 70.9%
4281985 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 48.0 4.28e-01 77.2% 88.6%
5021023 2008.1.1.4 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 0.64 50.0 3.79e-01 85.1% 35.6%
5047946 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.64 46.0 3.57e-01 75.2% 89.5%
3941001 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.63 52.0 3.76e-01 91.1% 51.3%
3643068 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.63 49.0 4.38e-01 83.2% 62.9%
4649366 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.62 45.0 3.19e-01 74.3% 91.2%
3965725 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.62 46.0 3.68e-01 79.2% 65.1%
3250178 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 46.0 3.99e-01 79.2% 54.8%
4032749 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.61 55.0 4.33e-01 99.0% 72.2%
3721181 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 48.0 3.72e-01 87.1% 71.1%
4116357 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 46.0 3.77e-01 82.2% 67.9%
3936765 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.60 48.0 3.73e-01 86.1% 79.5%
4576287 3755.3.1.471 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin 0.60 41.0 3.60e-01 71.3% 74.2%
3887920 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 46.0 4.00e-01 82.2% 72.3%
3215082 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.59 41.0 3.72e-01 72.3% 53.3%
5001630 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.59 48.0 4.00e-01 87.1% 58.2%
3286912 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.59 40.0 4.18e-01 72.3% 75.8%
3716307 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.58 44.0 3.35e-01 84.2% 33.8%
4988301 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.58 46.0 3.98e-01 83.2% 76.7%
3713780 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 45.0 4.23e-01 83.2% 71.2%
3610437 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.58 43.0 3.48e-01 84.2% 39.5%
5064482 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 40.0 3.41e-01 74.3% 44.2%
3470838 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 50.0 4.06e-01 99.0% 73.0%
3961873 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.57 43.0 3.95e-01 78.2% 60.8%
3184140 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.56 41.0 3.99e-01 76.2% 75.7%
4025954 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.56 47.0 3.54e-01 91.1% 75.2%
3658685 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.56 41.0 3.99e-01 76.2% 89.6%
4032384 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.56 41.0 4.47e-01 99.0% 97.5%
4004067 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 40.0 4.31e-01 75.2% 89.4%
3612509 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.56 43.0 3.27e-01 82.2% 58.8%
3240456 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 42.0 4.50e-01 83.2% 100.0%
3913307 192.4.1.0 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.55 38.0 4.00e-01 74.3% 80.0%
4262528 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 49.0 3.90e-01 100.0% 75.1%
4331100 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 41.0 4.21e-01 78.2% 87.4%
3929572 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.54 41.0 4.41e-01 100.0% 96.5%
4056158 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 41.0 4.04e-01 80.2% 80.0%
3433560 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 49.0 3.86e-01 99.0% 72.2%
3607831 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.54 38.0 3.82e-01 71.3% 78.0%
3718498 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.54 40.0 4.28e-01 90.1% 90.0%
3654118 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 46.0 3.65e-01 99.0% 69.5%
3216584 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.52 40.0 4.11e-01 88.1% 86.3%
3584048 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 39.0 4.04e-01 93.1% 90.0%