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iap-3

Euk-Vir

Hemileuca_sp._nucleopolyhedrovirus

iap-3__YP_008378255__Hemileuca_sp._nucleopolyhedrovirus__1367203

Identity

Accession:
YP_008378255 ↗
Protein ID:
iap-3
Kingdom:
euk

Quality

75.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-88
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00653.28 best BIR 40.7 4.00e-10 77.4% 95.7%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3siqA00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.79 71.0 6.57e-01 96.4% 90.3%
2poiA00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.77 63.0 6.50e-01 86.9% 94.9%
1f3hB00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.77 65.0 5.47e-01 90.5% 61.5%
1i3oF00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.77 58.0 5.62e-01 89.3% 72.0%
1f9xA00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.66 59.0 5.29e-01 100.0% 71.8%
2dk7A00 2.20.70.10 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › 0.58 30.0 3.24e-01 86.9% 56.2%
2wsaA00 3.40.630.170 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › 0.57 46.0 3.01e-01 90.5% 87.6%
4j4hA01 3.40.50.12150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 38.0 3.27e-01 70.2% 65.9%
3s79A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.53 44.0 2.83e-01 95.2% 71.9%
2y8nB02 2.20.70.100 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › 0.51 28.0 3.39e-01 70.2% 100.0%
1iizA00 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.50 42.0 3.79e-01 95.2% 95.0%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3938555 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.83 65.0 6.40e-01 83.3% 96.7%
4499664 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.80 67.0 7.03e-01 88.1% 100.0%
4024808 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.80 66.0 6.74e-01 86.9% 97.5%
3551266 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.80 67.0 5.71e-01 89.3% 58.5%
3874336 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.80 67.0 6.72e-01 89.3% 89.4%
166845 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.79 68.0 6.27e-01 90.5% 76.7%
4094681 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.79 66.0 5.08e-01 89.3% 42.5%
3557224 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.78 68.0 6.78e-01 92.9% 94.1%
426822 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.78 70.0 6.40e-01 96.4% 86.1%
3244185 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.78 66.0 5.53e-01 91.7% 61.4%
3216260 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.78 64.0 6.05e-01 88.1% 89.0%
3485145 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.78 66.0 5.59e-01 91.7% 60.7%
3309853 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.77 61.0 6.09e-01 83.3% 100.0%
3255526 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.77 63.0 6.18e-01 86.9% 98.9%
4030229 381.1.1.2 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Rsm1 0.77 60.0 6.17e-01 82.1% 98.8%
3865601 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.77 64.0 6.42e-01 89.3% 90.6%
3863964 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.77 63.0 6.09e-01 88.1% 94.7%
3244186 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.76 64.0 5.71e-01 91.7% 71.7%
3167513 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.75 62.0 5.74e-01 88.1% 97.1%
3492215 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.75 60.0 5.65e-01 92.9% 72.4%
3740617 381.1.1.2 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Rsm1 0.74 61.0 5.27e-01 88.1% 91.2%
154260 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.74 69.0 6.24e-01 100.0% 77.1%
4846647 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.73 67.0 6.21e-01 100.0% 88.6%
3993705 381.1.1.2 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Rsm1 0.71 59.0 5.50e-01 90.5% 96.2%
3171946 381.1.1.0 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat 0.63 53.0 5.05e-01 90.5% 84.8%
3803829 386.1.1.4 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.62 42.0 4.82e-01 70.2% 100.0%
3506303 386.1.1.4 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.61 39.0 4.27e-01 72.6% 83.1%
3321768 386.1.1.207 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED_2 0.60 40.0 4.25e-01 70.2% 88.0%
None 0.60 42.0 4.69e-01 73.8% 98.5%
4459875 330.3.1.0 a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.59 35.0 4.19e-01 76.2% 98.0%
3925231 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.59 40.0 4.52e-01 73.8% 98.3%
3652022 386.1.1.207 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED_2 0.59 41.0 4.19e-01 72.6% 82.5%
3935829 386.1.1.4 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.59 39.0 4.47e-01 71.4% 98.3%
3448806 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.57 39.0 4.36e-01 70.2% 100.0%
3179779 330.3.1.0 a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.56 36.0 3.55e-01 78.6% 60.0%
3357726 386.1.1.207 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED_2 0.55 44.0 4.59e-01 86.9% 97.3%
3662297 386.1.1.207 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED_2 0.54 42.0 4.02e-01 94.0% 71.0%
D2 high residues 97-192
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00653.28 best BIR 73.8 1.80e-20 69.8% 97.1%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2poiA00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.96 73.0 8.16e-01 79.2% 96.2%
1i3oF00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.94 70.0 7.19e-01 86.5% 79.6%
3siqA00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.90 74.0 7.25e-01 85.4% 92.2%
1f3hB00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.88 69.0 6.02e-01 81.2% 60.7%
1f9xA00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.81 74.0 6.87e-01 97.9% 81.2%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4094681 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.96 79.0 6.16e-01 85.4% 45.3%
4499664 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.96 73.0 8.32e-01 80.2% 100.0%
154260 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.96 90.0 8.55e-01 100.0% 85.3%
3551266 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.93 74.0 6.54e-01 83.3% 60.8%
3874336 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.93 74.0 7.86e-01 83.3% 92.9%
4846647 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.93 85.0 8.23e-01 95.8% 88.6%
3557224 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.92 76.0 8.06e-01 85.4% 95.3%
166845 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.92 76.0 7.40e-01 85.4% 79.6%
426822 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.91 74.0 7.05e-01 83.3% 87.0%
3865601 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.91 74.0 7.89e-01 85.4% 95.3%
3492215 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.90 68.0 6.81e-01 88.5% 76.5%
3742070 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.89 75.0 7.73e-01 86.5% 100.0%
3630296 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.89 72.0 6.07e-01 83.3% 59.3%
3187663 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.88 74.0 7.18e-01 87.5% 100.0%
3485145 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.88 70.0 6.08e-01 82.3% 60.7%
3244186 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.87 69.0 6.31e-01 82.3% 70.0%
3178326 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.85 69.0 6.61e-01 85.4% 95.4%
3220527 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.84 67.0 5.95e-01 82.3% 62.5%
3392094 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.83 70.0 6.16e-01 87.5% 63.2%
3783921 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.82 70.0 6.74e-01 88.5% 92.4%
3244185 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.82 70.0 6.00e-01 88.5% 62.1%
3938555 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.80 58.0 5.98e-01 75.0% 96.7%
3255526 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.79 60.0 6.18e-01 78.1% 97.8%
3742071 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.79 65.0 6.65e-01 86.5% 96.8%
3216260 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.79 59.0 5.85e-01 78.1% 88.0%
3721103 381.1.1.1 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.78 68.0 6.80e-01 91.7% 90.8%
3309853 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.76 57.0 6.07e-01 78.1% 100.0%
4030229 381.1.1.2 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Rsm1 0.76 54.0 5.84e-01 72.9% 96.2%
4024808 381.1.1.3 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC 0.76 57.0 6.19e-01 78.1% 96.2%
3993705 381.1.1.2 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Rsm1 0.74 56.0 5.48e-01 79.2% 90.5%
3171946 381.1.1.0 few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat 0.58 48.0 4.80e-01 88.5% 92.9%
4989650 148.1.3.19 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 0.54 38.0 3.97e-01 75.0% 87.8%