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immediate_early_protein_1

Euk-Vir

Murid_betaherpesvirus_8

immediate_early_protein_1__YP_007016516__Murid_betaherpesvirus_8__1261657

Identity

Accession:
YP_007016516 ↗
Protein ID:
immediate_early_protein_1
Kingdom:
euk

Quality

53.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Muromegalovirus› Murid_betaherpesvirus_8

TaxID: 1261657

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 87-143_234-307
PDB
D2 medium residues 144-233_308-401
PDB
Domain cluster: rep: regulatory_protein_IE1__YP_002608299__Human_herpesvirus_5__10359__D73-95_143-185_223-391
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.70 49.0 5.27e-01 71.2% 89.8%
4bemJ00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.66 47.0 4.76e-01 71.7% 90.6%
4bejB02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.65 46.0 4.31e-01 72.8% 58.7%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 43.0 3.93e-01 70.7% 83.7%
6o7uc01 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.60 46.0 4.62e-01 99.5% 76.8%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 42.0 3.73e-01 70.7% 85.9%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 40.0 3.54e-01 70.7% 81.9%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.56 28.0 3.22e-01 82.1% 61.8%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.55 42.0 4.44e-01 82.1% 88.2%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 41.0 3.79e-01 77.7% 81.1%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.53 34.0 3.85e-01 81.0% 86.8%
4k7rA01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.52 48.0 3.87e-01 99.5% 86.3%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 40.0 3.46e-01 79.9% 78.5%
3ggyA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.50 38.0 3.85e-01 77.7% 84.4%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4581508 601.19.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein 0.67 45.0 4.28e-01 82.6% 57.6%
3385053 5076.2.1.10 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.67 51.0 4.48e-01 85.9% 53.7%
3601971 5041.1.1.0 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.61 45.0 4.74e-01 98.9% 84.8%
5071140 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.61 41.0 4.52e-01 77.2% 83.3%
3412891 150.1.1.31 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety 0.58 41.0 3.54e-01 70.7% 67.3%
3854050 604.12.1.43 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Tim17 0.57 36.0 4.13e-01 90.8% 83.7%
3187115 5038.2.1.1 ↗ alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.56 39.0 4.39e-01 82.1% 90.3%
3920609 150.1.1.31 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety 0.56 39.0 3.44e-01 70.7% 72.4%
5054822 5076.2.1.3 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF4013 0.56 39.0 3.78e-01 82.1% 62.9%
3741762 4177.1.1.8 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.54 38.0 3.46e-01 71.2% 72.0%
4333666 109.46.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH 0.54 41.0 3.39e-01 78.8% 53.1%
3614810 1189.1.1.0 ↗ alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.54 39.0 4.22e-01 75.0% 88.4%
3279521 1075.5.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.54 39.0 3.86e-01 73.9% 95.3%
3624654 1075.1.1.4 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.53 42.0 3.73e-01 82.6% 68.8%
4996693 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 40.0 3.79e-01 78.3% 75.9%
4470940 1075.4.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.52 37.0 2.97e-01 70.7% 41.4%
3250233 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.52 32.0 3.25e-01 82.1% 60.0%
3316951 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.52 41.0 3.84e-01 82.6% 83.0%
3440913 4006.1.1.0 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.52 35.0 4.10e-01 83.7% 94.8%
3635836 3291.1.1.3 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Ist1 0.51 40.0 3.95e-01 80.4% 84.5%
3799718 11.2.1.25 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PL48 0.50 40.0 3.59e-01 82.1% 98.0%
4955609 1075.1.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.50 38.0 3.40e-01 77.7% 81.5%