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immediate_early_protein_ICP0

Euk-Vir

Leporid_alphaherpesvirus_4

immediate_early_protein_ICP0__YP_009230192__Leporid_alphaherpesvirus_4__481315

Identity

Accession:
YP_009230192 ↗
Protein ID:
immediate_early_protein_ICP0
Kingdom:
euk

Quality

48.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Leporid_alphaherpesvirus_4

TaxID: 481315

Cluster

View cluster (2 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 71-135
PDB
Domain cluster: rep: orf75__YP_009186766__Sucra_jujuba_nucleopolyhedrovirus__1563660__D78-126
Pfam (4)
AccessionNameScoreE-valueQ covHMM cov
PF13920.13 best zf-C3HC4_3 28.2 1.80e-06 80.0% 91.8%
PF13639.13 zf-RING_2 43.1 5.60e-11 67.7% 97.7%
PF13923.13 zf-C3HC4_2 38.8 8.90e-10 64.6% 97.5%
PF00097.32 zf-C3HC4 42.4 7.00e-11 63.1% 100.0%
D2 medium residues 136-186
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ez4B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 61.0 4.48e-01 98.0% 40.4%
6iheA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.72 61.0 4.52e-01 100.0% 42.9%
1hyhA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 59.0 4.42e-01 100.0% 42.6%
4zeoH02 3.40.50.10470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 0.67 57.0 4.11e-01 100.0% 34.4%
2xveA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.66 53.0 4.35e-01 100.0% 47.0%
1id1A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 54.0 3.98e-01 100.0% 32.7%
2yeqA02 3.60.21.70 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Alkaline phosphatase D (PhoD) 0.65 54.0 3.26e-01 100.0% 26.2%
1x7dA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 55.0 3.89e-01 100.0% 32.4%
2i99A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 52.0 3.82e-01 100.0% 32.1%
1onfA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.63 54.0 4.20e-01 100.0% 50.0%
3bvpB00 3.40.50.1390 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Resolvase, N-terminal catalytic domain 0.63 52.0 4.04e-01 100.0% 76.2%
1ufvA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.63 53.0 3.76e-01 100.0% 40.1%
2dxnA02 3.30.750.180 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › GpdQ, beta-strand dimerisation domain 0.63 52.0 4.05e-01 100.0% 75.4%
3qd5A00 3.40.1400.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribose 5-phosphate Isomerase B; Chain: A, › Sugar-phosphate isomerase, RpiB/LacA/LacB 0.62 52.0 3.79e-01 100.0% 66.9%
3bamA00 3.40.91.20 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.62 52.0 3.55e-01 100.0% 34.0%
3c3kB01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 50.0 3.86e-01 100.0% 70.1%
5oynA01 3.50.30.80 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › IlvD/EDD C-terminal domain-like 0.61 49.0 3.61e-01 100.0% 47.9%
1zq1A02 3.40.50.1170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › L-asparaginase, N-terminal domain 0.60 49.0 3.36e-01 100.0% 77.0%
5nckA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 49.0 4.03e-01 100.0% 98.1%
7tjbA01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.59 49.0 3.40e-01 100.0% 63.1%
8gr2A01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.59 49.0 3.43e-01 100.0% 74.9%
1xc3A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.59 49.0 4.03e-01 100.0% 97.1%
3rssA01 3.40.50.10260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › YjeF N-terminal domain 0.59 47.0 3.25e-01 98.0% 27.0%
3hh8A02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.58 48.0 3.72e-01 100.0% 59.5%
5kcnA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 46.0 3.89e-01 100.0% 86.9%
3iveA01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.57 47.0 2.97e-01 100.0% 20.7%
3p9xA00 3.40.50.170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain 0.56 46.0 3.22e-01 100.0% 27.2%
2fywA01 3.40.1390.30 Alpha Beta › 3-Layer(aba) Sandwich › Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 › NIF3 (NGG1p interacting factor 3)-like 0.55 46.0 3.54e-01 100.0% 45.4%
3ffrA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.53 42.0 2.84e-01 100.0% 22.3%
1sz2B01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 40.0 3.27e-01 100.0% 77.5%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4949763 2003.1.1.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Ldh_1_N 0.70 58.0 4.39e-01 98.0% 41.5%
5012344 2008.1.1.114 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF4143 0.65 53.0 4.36e-01 98.0% 55.2%
4982610 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.65 54.0 3.61e-01 100.0% 38.7%
149376 246.2.1.8 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › PhoD 0.65 54.0 3.26e-01 100.0% 26.2%
4967919 7512.1.1.31 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.64 47.0 3.42e-01 88.2% 27.3%
4972423 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.64 54.0 3.81e-01 100.0% 32.0%
5045517 2004.1.1.146 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.63 50.0 3.22e-01 92.2% 21.5%
3990066 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.62 52.0 4.21e-01 100.0% 47.6%
4997998 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.62 53.0 3.70e-01 100.0% 31.1%
4996456 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.62 51.0 3.57e-01 100.0% 30.5%
4997992 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.61 53.0 3.61e-01 100.0% 29.7%
4972755 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.61 51.0 3.61e-01 100.0% 30.8%
4999944 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.61 50.0 3.59e-01 100.0% 32.8%
3601536 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 49.0 3.65e-01 100.0% 75.8%
3959193 2003.1.2.12 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › DAO 0.61 50.0 3.59e-01 98.0% 99.4%
5029706 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.61 49.0 3.45e-01 100.0% 31.5%
4932611 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.61 52.0 4.08e-01 100.0% 64.3%
4102835 7566.1.1.1 ↗ a/b three-layered sandwiches › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › GTP-bdg_N,GTP-bdg_M 0.61 51.0 3.62e-01 100.0% 69.1%
5009562 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.61 50.0 3.73e-01 100.0% 34.7%
4963595 7512.1.1.31 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.61 53.0 3.76e-01 100.0% 37.5%
5053394 2003.1.4.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.60 51.0 3.36e-01 100.0% 35.1%
4990049 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.60 52.0 3.66e-01 100.0% 33.1%
5007752 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.60 49.0 3.42e-01 100.0% 29.2%
3593126 2007.3.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains 0.59 48.0 3.49e-01 100.0% 73.1%
4012254 2007.3.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains 0.59 49.0 3.55e-01 100.0% 76.5%
4982881 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.59 50.0 3.59e-01 100.0% 31.8%
4948399 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.59 48.0 3.35e-01 100.0% 78.5%
5061175 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.59 49.0 3.52e-01 100.0% 29.1%
5038574 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.59 50.0 3.14e-01 100.0% 40.7%
4999410 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.59 50.0 3.36e-01 100.0% 27.0%
4438121 2002.1.1.348 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DUF6259 0.59 47.0 2.92e-01 100.0% 37.9%
5016073 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.59 49.0 3.43e-01 100.0% 27.9%
4010895 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.58 50.0 3.94e-01 100.0% 81.7%
4945908 246.2.1.9 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos_2 0.58 46.0 3.43e-01 100.0% 46.1%
1211213 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.57 47.0 2.97e-01 100.0% 21.6%
3997363 2498.1.1.0 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.57 48.0 2.95e-01 98.0% 18.9%
3813073 2004.1.1.73 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.56 45.0 3.22e-01 100.0% 41.1%
3751048 7512.1.1.1 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.55 43.0 3.22e-01 100.0% 76.4%
3802411 2499.1.1.0 ↗ a/b three-layered sandwiches › Subtilisin-like › Subtilisin-like › Subtilisin-like 0.55 43.0 3.51e-01 100.0% 43.3%
3584655 7566.1.1.2 ↗ a/b three-layered sandwiches › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › GTP-bdg_N 0.54 44.0 3.05e-01 100.0% 63.8%
3990078 2007.1.2.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_1 0.54 43.0 3.52e-01 100.0% 68.7%
3860717 2498.1.1.9 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.54 39.0 2.47e-01 78.4% 56.6%
3838900 2008.1.1.152 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF2130 0.54 44.0 3.22e-01 98.0% 38.1%
2567208 247.1.1.10 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › DRMBL,Lactamase_B_2 0.53 40.0 2.60e-01 100.0% 15.4%
3548868 2498.1.1.9 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.52 43.0 2.78e-01 92.2% 54.9%
3546292 2498.1.1.9 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.51 41.0 2.57e-01 92.2% 49.2%