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inner_core

Euk-Vir

Wallal_virus

inner_core__YP_008658418__Wallal_virus__40061

Identity

Accession:
YP_008658418 ↗
Protein ID:
inner_core
Kingdom:
euk

Quality

81.0 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Resentoviricetes› Reovirales› Sedoreoviridae› Orbivirus› Wallal_virus

TaxID: 40061

Cluster

View cluster (13 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 27-38_229-304_334-359_870-899
PDB
Domain cluster: rep: VP3__YP_009507697__Eubenangee_virus__40056__D226-299_587-622_880-900
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF01700.23 best Orbi_VP3 123.2 1.00e-35 60.4% 8.8%
PF01700.23 Orbi_VP3 28.4 4.90e-07 22.2% 3.4%
PF01700.23 Orbi_VP3 34.1 9.50e-09 20.1% 3.0%
D2 medium residues 143-228
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01700.23 best Orbi_VP3 106.8 1.00e-30 100.0% 9.6%
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wp1B01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.60 43.0 2.85e-01 74.4% 60.6%
1zcdA00 1.20.1530.10 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain 0.54 47.0 3.10e-01 97.7% 77.4%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.54 31.0 2.51e-01 100.0% 28.7%
6u9hF02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.53 29.0 3.10e-01 96.5% 57.1%
3oduB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 41.0 3.02e-01 89.5% 89.5%
2fgcA03 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.52 28.0 2.99e-01 96.5% 55.3%
4qt4A00 3.40.50.1470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase 0.51 36.0 2.87e-01 73.3% 98.4%
2l48A00 3.30.70.2030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 29.0 2.97e-01 96.5% 55.3%
2uv8A05 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.51 42.0 2.66e-01 100.0% 72.8%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.51 27.0 3.29e-01 75.6% 81.8%
4djhA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 39.0 2.85e-01 87.2% 65.5%
2bzlA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 38.0 2.69e-01 80.2% 49.6%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1409638 4064.1.1.1 ↗ a+b complex topology › Inner layer core protein p3-related › Inner layer core protein p3-related › Inner layer core protein p3-related › Orbi_VP3 0.91 88.0 4.86e-01 100.0% 9.7%
5050596 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.57 32.0 3.48e-01 96.5% 67.1%
4442629 3563.1.1.1 ↗ alpha bundles › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › TatC 0.57 48.0 3.50e-01 96.5% 53.9%
3240839 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 45.0 3.09e-01 89.5% 79.1%
4590927 304.28.1.2 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG 0.55 31.0 3.12e-01 97.7% 52.2%
3415024 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.55 43.0 3.04e-01 90.7% 80.0%
3909510 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 45.0 3.06e-01 94.2% 78.6%
3907411 5001.1.1.111 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1, 7TM_GPCR_Srw 0.54 42.0 2.91e-01 86.0% 63.0%
4490186 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 43.0 2.98e-01 90.7% 77.7%
3879591 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 44.0 3.05e-01 94.2% 82.2%
3491073 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 40.0 2.83e-01 86.0% 88.2%
None — 0.52 43.0 2.96e-01 95.3% 66.3%
3466238 206.1.1.14 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.51 42.0 2.68e-01 89.5% 39.8%
3932224 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 42.0 2.99e-01 95.3% 69.7%
4999286 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.50 35.0 2.76e-01 72.1% 70.0%
D3 medium residues 305-333_360-411
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01700.23 best Orbi_VP3 74.4 6.10e-21 65.4% 5.8%
PF01700.23 Orbi_VP3 31.5 5.50e-08 39.5% 3.4%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.61 38.0 4.28e-01 85.2% 83.6%
3whjA00 6.10.140.1710 Special › Helix non-globular › Helix Hairpins › 0.61 37.0 3.37e-01 93.8% 45.0%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.55 40.0 3.67e-01 82.7% 57.7%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 37.0 4.20e-01 90.1% 100.0%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.54 33.0 3.11e-01 80.2% 52.6%
3ha4B00 1.20.58.690 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 38.0 3.39e-01 75.3% 72.5%
3di1A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 44.0 3.06e-01 93.8% 44.1%
2yksA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.52 35.0 3.14e-01 85.2% 47.9%
3efzB00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.51 45.0 3.31e-01 100.0% 66.2%
7dwqL01 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.51 33.0 2.90e-01 86.4% 44.0%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3229806 6157.1.1.1 ↗ alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP 0.59 40.0 3.54e-01 82.7% 49.6%
3474500 632.7.1.25 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › PF27508 0.59 36.0 3.54e-01 80.2% 57.6%
4486891 5059.1.1.5 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.56 42.0 2.85e-01 100.0% 20.3%
4022456 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 44.0 3.60e-01 95.1% 57.3%
3391109 3684.1.1.21 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › TMEM138 0.51 40.0 3.34e-01 85.2% 48.6%
3598146 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 41.0 3.85e-01 87.7% 72.0%
D4 medium residues 412-450_483-537
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01700.23 best Orbi_VP3 77.6 6.50e-22 58.5% 6.2%
PF01700.23 Orbi_VP3 51.3 5.70e-14 43.6% 4.4%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5y27A00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.67 37.0 3.71e-01 79.8% 52.0%
1jfiB00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.63 41.0 3.66e-01 88.3% 45.9%
3g27A01 3.30.50.20 Alpha Beta › 2-Layer Sandwich › Erythroid Transcription Factor GATA-1; Chain A › prophage-derive protein ybcO 0.52 35.0 3.93e-01 80.9% 98.5%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1409638 4064.1.1.1 ↗ a+b complex topology › Inner layer core protein p3-related › Inner layer core protein p3-related › Inner layer core protein p3-related › Orbi_VP3 0.91 87.0 4.87e-01 100.0% 14.2%
5020630 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 37.0 3.17e-01 88.3% 43.3%
D5 medium residues 592-697
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01700.23 best Orbi_VP3 148.0 3.40e-43 100.0% 11.8%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2f48A03 1.10.10.480 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Phosphofructokinase; domain 3 0.65 42.0 4.81e-01 72.6% 92.0%
5fglA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 46.0 3.70e-01 73.6% 54.0%
1ulyA02 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.62 36.0 3.68e-01 83.0% 59.4%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 44.0 4.25e-01 73.6% 94.9%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.60 45.0 3.80e-01 79.2% 69.0%
3k8pC02 1.10.357.150 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.58 42.0 3.49e-01 75.5% 44.7%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.58 44.0 4.18e-01 79.2% 84.8%
3fhnA03 1.10.357.100 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C 0.55 39.0 3.30e-01 71.7% 46.6%
1bgwA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.55 42.0 4.22e-01 81.1% 92.7%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.55 41.0 4.00e-01 80.2% 87.5%
7tzoA01 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.54 40.0 3.46e-01 78.3% 86.8%
2chpA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 48.0 4.28e-01 100.0% 98.6%
3i7aA00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.52 47.0 3.40e-01 98.1% 53.8%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1409638 4064.1.1.1 ↗ a+b complex topology › Inner layer core protein p3-related › Inner layer core protein p3-related › Inner layer core protein p3-related › Orbi_VP3 0.94 90.0 5.10e-01 100.0% 12.0%
5032443 601.1.3.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 0.62 48.0 3.81e-01 81.1% 73.3%
3740294 3826.1.1.0 ↗ alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.60 41.0 3.65e-01 83.0% 50.0%
3389029 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 42.0 4.13e-01 73.6% 75.7%
3998516 5050.1.1.6 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP 0.59 44.0 3.55e-01 80.2% 69.8%
4167208 604.15.1.0 ↗ alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.58 32.0 3.98e-01 92.5% 93.3%
4029359 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 42.0 3.93e-01 74.5% 83.7%
3672309 601.19.1.29 ↗ alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › CA109-like 0.57 43.0 3.68e-01 80.2% 95.4%
4206404 103.4.1.26 ↗ alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Rod-binding 0.56 40.0 4.28e-01 75.5% 98.9%
3988293 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 45.0 3.72e-01 88.7% 88.9%
3456942 5048.1.1.1 ↗ alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP 0.54 48.0 4.23e-01 95.3% 72.0%
4019408 129.1.1.64 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › DUF7624 0.54 47.0 4.26e-01 92.5% 87.8%
3482907 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.52 48.0 4.71e-01 100.0% 96.5%
4027360 603.2.1.0 ↗ alpha bundles › STAT-like › STAT › STAT 0.52 44.0 3.27e-01 89.6% 40.8%
D6 medium residues 698-864
PDB
Domain cluster: rep: VP3__YP_009507697__Eubenangee_virus__40056__D698-861
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01700.23 best Orbi_VP3 235.4 1.30e-69 100.0% 18.7%