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integral_membrane_protein
Euk-VirHuman_betaherpesvirus_6A
integral_membrane_protein__NP_042965__Human_betaherpesvirus_6A__32603
Identity
- Accession:
- NP_042965 ↗
- Protein ID:
- integral_membrane_protein
- Kingdom:
- euk
Quality
82.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Roseolovirus›
Human_betaherpesvirus_6A
TaxID: 32603
Cluster
View cluster (76 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-50_66-144
Domain cluster:
rep: BBRF3__YP_001129479__Human_herpesvirus_4_type_2__12509__D4-36_71-130
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 94.9 | 7.70e-27 | 95.3% | 41.2% |
CATH (62)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 48.0 | 6.00e-01 | 72.9% | 98.7% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.78 | 62.0 | 5.96e-01 | 98.4% | 72.8% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.77 | 44.0 | 5.34e-01 | 70.5% | 84.9% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.77 | 50.0 | 6.02e-01 | 96.9% | 97.7% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.77 | 61.0 | 5.71e-01 | 96.9% | 69.0% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.77 | 62.0 | 5.81e-01 | 97.7% | 70.3% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.76 | 62.0 | 5.84e-01 | 97.7% | 71.0% |
| 2pg0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.76 | 62.0 | 5.87e-01 | 97.7% | 73.2% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.74 | 56.0 | 5.40e-01 | 93.0% | 70.6% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 48.0 | 5.22e-01 | 92.2% | 78.7% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.74 | 45.0 | 4.68e-01 | 72.9% | 65.5% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 66.0 | 6.08e-01 | 98.4% | 78.0% |
| 1r8iA00 | 1.20.58.430 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Type IV secretion system, VirB5-domain | 0.72 | 66.0 | 5.77e-01 | 98.4% | 91.4% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.72 | 67.0 | 6.34e-01 | 99.2% | 86.5% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 44.0 | 4.55e-01 | 72.9% | 65.3% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 56.0 | 5.31e-01 | 94.6% | 70.7% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.71 | 50.0 | 4.17e-01 | 72.1% | 98.1% |
| 1u8vB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.70 | 56.0 | 4.72e-01 | 98.4% | 50.7% |
| 4cbeA00 | 1.20.120.1640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 46.0 | 3.90e-01 | 99.2% | 40.7% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.70 | 44.0 | 4.85e-01 | 72.9% | 79.2% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 47.0 | 4.90e-01 | 98.4% | 74.2% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.69 | 59.0 | 5.22e-01 | 99.2% | 63.0% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 61.0 | 4.96e-01 | 100.0% | 85.1% |
| 1yf2A02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.68 | 48.0 | 5.20e-01 | 72.1% | 99.1% |
| 6elqA01 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.68 | 62.0 | 5.56e-01 | 100.0% | 96.6% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 44.0 | 3.71e-01 | 72.1% | 39.5% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.67 | 48.0 | 4.11e-01 | 72.9% | 49.2% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 45.0 | 5.31e-01 | 72.9% | 100.0% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.67 | 62.0 | 5.30e-01 | 100.0% | 87.8% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.67 | 60.0 | 5.29e-01 | 97.7% | 95.7% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.66 | 55.0 | 4.96e-01 | 97.7% | 65.3% |
| 2p5tA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.66 | 46.0 | 5.25e-01 | 99.2% | 100.0% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.66 | 46.0 | 4.83e-01 | 72.9% | 78.2% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.65 | 46.0 | 4.87e-01 | 72.9% | 84.3% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 58.0 | 5.31e-01 | 97.7% | 74.3% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 46.0 | 4.33e-01 | 73.6% | 69.2% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 57.0 | 4.56e-01 | 98.4% | 85.4% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.64 | 53.0 | 5.07e-01 | 94.6% | 77.4% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 38.0 | 4.66e-01 | 72.1% | 97.4% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.64 | 57.0 | 5.05e-01 | 98.4% | 67.6% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.63 | 43.0 | 4.63e-01 | 97.7% | 80.4% |
| 3udcA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 39.0 | 4.19e-01 | 77.5% | 70.4% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.63 | 45.0 | 4.16e-01 | 73.6% | 74.5% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 52.0 | 4.12e-01 | 88.4% | 78.3% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 44.0 | 4.85e-01 | 73.6% | 95.3% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 54.0 | 4.39e-01 | 96.1% | 87.8% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 55.0 | 4.33e-01 | 100.0% | 92.9% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.60 | 41.0 | 4.10e-01 | 71.3% | 66.9% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.60 | 47.0 | 4.83e-01 | 93.8% | 86.1% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.60 | 50.0 | 5.27e-01 | 89.9% | 100.0% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 53.0 | 4.55e-01 | 98.4% | 95.2% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.59 | 42.0 | 4.05e-01 | 72.9% | 64.4% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.59 | 39.0 | 4.05e-01 | 93.0% | 72.9% |
| 1ux5A03 | 1.20.58.2220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain | 0.59 | 44.0 | 3.55e-01 | 77.5% | 61.1% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.57 | 50.0 | 3.75e-01 | 95.3% | 75.3% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.57 | 44.0 | 4.65e-01 | 80.6% | 97.3% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 50.0 | 4.10e-01 | 100.0% | 86.5% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.55 | 49.0 | 4.71e-01 | 96.9% | 83.8% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 41.0 | 3.54e-01 | 79.1% | 99.5% |
| 5yixA00 | 1.10.601.10 | Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor | 0.53 | 44.0 | 3.29e-01 | 88.4% | 85.5% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 47.0 | 3.99e-01 | 99.2% | 80.8% |
| 3rx6A00 | 1.20.58.1090 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer | 0.51 | 46.0 | 4.07e-01 | 98.4% | 100.0% |
ECOD (70)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3724018 | 3755.4.1.3 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Helo_like_N | 0.76 | 58.0 | 5.44e-01 | 94.6% | 65.8% |
| 3829240 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.74 | 64.0 | 6.61e-01 | 100.0% | 99.2% |
| 3801367 | 611.2.1.0 ↗ | alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) | 0.73 | 49.0 | 5.14e-01 | 94.6% | 73.3% |
| 3620978 | 2003.1.2.18 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.72 | 46.0 | 3.42e-01 | 72.9% | 26.2% |
| 3471633 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.71 | 65.0 | 5.33e-01 | 100.0% | 80.4% |
| 3624229 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.71 | 63.0 | 4.77e-01 | 94.6% | 75.8% |
| 3715936 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.70 | 49.0 | 4.38e-01 | 72.9% | 52.0% |
| 5040665 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.70 | 43.0 | 2.78e-01 | 72.9% | 14.0% |
| 3605105 | 1189.1.1.3 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP | 0.70 | 64.0 | 5.42e-01 | 100.0% | 89.0% |
| 3241030 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 62.0 | 4.58e-01 | 96.1% | 69.2% |
| 3607194 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.69 | 47.0 | 3.99e-01 | 72.9% | 44.5% |
| 3852296 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.68 | 62.0 | 5.63e-01 | 100.0% | 87.4% |
| 4049101 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.68 | 46.0 | 4.37e-01 | 71.3% | 59.3% |
| 3608743 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.67 | 61.0 | 4.80e-01 | 99.2% | 80.0% |
| 3921802 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.67 | 48.0 | 4.38e-01 | 72.9% | 60.0% |
| 3877415 | 604.1.1.118 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N | 0.67 | 47.0 | 4.33e-01 | 71.3% | 58.1% |
| 4927602 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 42.0 | 4.27e-01 | 71.3% | 63.1% |
| 3782183 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.66 | 49.0 | 3.30e-01 | 76.7% | 23.7% |
| 4026040 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.66 | 47.0 | 3.02e-01 | 72.9% | 40.4% |
| 3611289 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.66 | 46.0 | 4.47e-01 | 72.1% | 67.6% |
| 3880637 | 3755.3.1.465 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A | 0.66 | 45.0 | 4.39e-01 | 72.9% | 63.6% |
| 3479138 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.66 | 60.0 | 5.05e-01 | 100.0% | 86.0% |
| 1585161 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.66 | 59.0 | 5.38e-01 | 97.7% | 74.3% |
| 3466334 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 47.0 | 4.76e-01 | 97.7% | 73.8% |
| 4013341 | 3755.4.1.3 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Helo_like_N | 0.65 | 50.0 | 5.15e-01 | 94.6% | 83.2% |
| 3954586 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.65 | 46.0 | 4.17e-01 | 72.1% | 95.9% |
| 4561607 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.65 | 57.0 | 5.92e-01 | 97.7% | 100.0% |
| 3306310 | 192.29.1.115 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF599 | 0.65 | 59.0 | 5.64e-01 | 100.0% | 90.0% |
| 3560229 | 3291.1.1.230 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › TBCA_PH | 0.65 | 46.0 | 4.47e-01 | 72.1% | 68.6% |
| 3788539 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 49.0 | 3.42e-01 | 79.1% | 26.8% |
| 4497098 | 3291.1.1.195 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › H-kinase_dim | 0.64 | 46.0 | 4.76e-01 | 72.9% | 100.0% |
| 1759951 | 5086.1.1.88 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD | 0.64 | 46.0 | 3.98e-01 | 72.9% | 99.5% |
| 3592587 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.64 | 46.0 | 4.67e-01 | 72.9% | 76.0% |
| 4036645 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.64 | 45.0 | 3.94e-01 | 72.9% | 73.3% |
| 3169381 | 874.1.1.0 ↗ | a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain | 0.64 | 45.0 | 3.83e-01 | 72.1% | 44.9% |
| 3781640 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.64 | 46.0 | 3.93e-01 | 74.4% | 71.2% |
| 5052428 | 605.6.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like | 0.64 | 41.0 | 4.98e-01 | 77.5% | 100.0% |
| 5079633 | 7094.1.1.4 ↗ | alpha bundles › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › PF27273 | 0.64 | 41.0 | 5.00e-01 | 77.5% | 100.0% |
| 3402327 | 3755.3.1.324 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 | 0.63 | 45.0 | 4.07e-01 | 74.4% | 54.7% |
| 3482286 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.63 | 44.0 | 3.82e-01 | 72.1% | 92.0% |
| 3704105 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.63 | 45.0 | 4.14e-01 | 72.9% | 61.9% |
| 3947741 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.63 | 45.0 | 4.72e-01 | 74.4% | 92.5% |
| 3973283 | 325.1.7.27 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_AprE | 0.62 | 44.0 | 3.83e-01 | 72.9% | 73.3% |
| 4516566 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.62 | 44.0 | 3.85e-01 | 72.9% | 61.6% |
| 3839901 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.62 | 49.0 | 5.01e-01 | 89.9% | 84.8% |
| 4359654 | 605.2.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N | 0.62 | 45.0 | 4.83e-01 | 76.0% | 88.2% |
| 4554754 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 45.0 | 4.08e-01 | 74.4% | 78.2% |
| 4429833 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.62 | 44.0 | 4.75e-01 | 73.6% | 90.9% |
| 3936021 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.62 | 43.0 | 3.64e-01 | 71.3% | 53.3% |
| 3478838 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.61 | 54.0 | 4.20e-01 | 96.9% | 78.2% |
| 4023646 | 174.1.1.88 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7641 | 0.61 | 44.0 | 4.55e-01 | 99.2% | 77.6% |
| 4320014 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.61 | 46.0 | 3.55e-01 | 77.5% | 82.2% |
| 5049284 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.61 | 43.0 | 4.50e-01 | 72.9% | 90.8% |
| 3812652 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.61 | 43.0 | 3.76e-01 | 72.9% | 77.9% |
| 3471424 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.61 | 43.0 | 3.68e-01 | 72.9% | 49.3% |
| 4120406 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.61 | 44.0 | 4.75e-01 | 75.2% | 89.1% |
| 4950734 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.61 | 42.0 | 3.72e-01 | 71.3% | 93.2% |
| 4424778 | 605.2.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N | 0.60 | 43.0 | 4.63e-01 | 72.9% | 86.4% |
| 3712573 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.60 | 43.0 | 4.19e-01 | 72.9% | 68.6% |
| 3414501 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 50.0 | 4.86e-01 | 92.2% | 80.7% |
| 3742152 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.59 | 51.0 | 4.21e-01 | 92.2% | 92.0% |
| 3625262 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.59 | 47.0 | 4.34e-01 | 86.8% | 78.8% |
| 3400571 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.57 | 46.0 | 4.37e-01 | 86.0% | 87.1% |
| 3880351 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.57 | 49.0 | 4.07e-01 | 100.0% | 52.6% |
| 3499207 | 133.1.1.0 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) | 0.56 | 49.0 | 4.10e-01 | 100.0% | 55.5% |
| 3727661 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.56 | 47.0 | 4.54e-01 | 96.9% | 80.0% |
| 3654456 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.55 | 49.0 | 3.72e-01 | 98.4% | 62.0% |
| 4627992 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.52 | 47.0 | 3.47e-01 | 96.9% | 64.4% |
| 4460475 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.51 | 42.0 | 4.19e-01 | 86.8% | 83.8% |
| 3515126 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.51 | 47.0 | 4.27e-01 | 100.0% | 92.0% |
D2
medium
residues 145-219
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 59.6 | 4.10e-16 | 100.0% | 23.0% |
CATH (73)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.88 | 66.0 | 7.41e-01 | 77.3% | 100.0% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.86 | 66.0 | 7.07e-01 | 96.0% | 95.3% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.85 | 76.0 | 6.64e-01 | 97.3% | 87.2% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 72.0 | 7.01e-01 | 96.0% | 85.2% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 76.0 | 6.08e-01 | 97.3% | 62.6% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.84 | 74.0 | 6.53e-01 | 96.0% | 71.0% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.84 | 64.0 | 6.04e-01 | 89.3% | 69.0% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.83 | 73.0 | 7.16e-01 | 94.7% | 100.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.83 | 72.0 | 6.82e-01 | 97.3% | 80.2% |
| 3jcuZ00 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.83 | 64.0 | 7.00e-01 | 82.7% | 100.0% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.83 | 74.0 | 6.53e-01 | 97.3% | 68.9% |
| 4i0xH00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.82 | 70.0 | 6.99e-01 | 92.0% | 98.7% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.82 | 68.0 | 6.69e-01 | 98.7% | 84.0% |
| 2zdiB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 72.0 | 6.37e-01 | 97.3% | 91.5% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.81 | 71.0 | 6.33e-01 | 97.3% | 71.0% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.81 | 71.0 | 6.36e-01 | 96.0% | 70.9% |
| 3t98B00 | 6.10.140.1350 | Special › Helix non-globular › Helix Hairpins › | 0.81 | 70.0 | 6.65e-01 | 96.0% | 81.4% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.81 | 65.0 | 6.99e-01 | 85.3% | 100.0% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.80 | 70.0 | 6.62e-01 | 93.3% | 83.0% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.80 | 69.0 | 5.72e-01 | 96.0% | 60.2% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.80 | 72.0 | 6.16e-01 | 98.7% | 64.0% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.80 | 60.0 | 6.38e-01 | 93.3% | 93.8% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.79 | 69.0 | 6.02e-01 | 97.3% | 75.7% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.79 | 68.0 | 5.98e-01 | 96.0% | 67.9% |
| 2cazD00 | 6.10.140.820 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 59.0 | 6.48e-01 | 82.7% | 100.0% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.77 | 69.0 | 5.51e-01 | 98.7% | 81.5% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.77 | 64.0 | 6.55e-01 | 94.7% | 94.5% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.77 | 67.0 | 6.04e-01 | 94.7% | 71.6% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.77 | 67.0 | 6.84e-01 | 94.7% | 100.0% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 64.0 | 6.43e-01 | 93.3% | 88.3% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 65.0 | 5.31e-01 | 96.0% | 54.2% |
| 1bhaA00 | 1.10.287.170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 54.0 | 5.74e-01 | 93.3% | 83.6% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.76 | 67.0 | 5.27e-01 | 100.0% | 83.9% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 67.0 | 5.90e-01 | 97.3% | 89.0% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 62.0 | 6.19e-01 | 88.0% | 85.5% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 70.0 | 6.19e-01 | 100.0% | 76.9% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.75 | 66.0 | 5.97e-01 | 96.0% | 91.1% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 65.0 | 5.86e-01 | 94.7% | 74.3% |
| 3aeiA00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 64.0 | 6.01e-01 | 96.0% | 100.0% |
| 3tklB01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 54.0 | 5.79e-01 | 100.0% | 91.9% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 60.0 | 6.15e-01 | 98.7% | 93.0% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.74 | 60.0 | 5.11e-01 | 86.7% | 56.8% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 63.0 | 6.01e-01 | 96.0% | 93.2% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.73 | 65.0 | 4.90e-01 | 100.0% | 53.6% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 63.0 | 5.68e-01 | 96.0% | 71.6% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 64.0 | 4.97e-01 | 100.0% | 73.2% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 56.0 | 5.16e-01 | 94.7% | 63.6% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 51.0 | 5.17e-01 | 100.0% | 74.0% |
| 1yf2A02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.72 | 60.0 | 5.44e-01 | 94.7% | 94.4% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 63.0 | 5.25e-01 | 100.0% | 58.8% |
| 1owaA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 61.0 | 5.49e-01 | 100.0% | 68.9% |
| 3zdqA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.71 | 61.0 | 3.98e-01 | 94.7% | 23.7% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 61.0 | 4.83e-01 | 97.3% | 56.6% |
| 2yevC00 | 6.10.280.110 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 53.0 | 5.71e-01 | 82.7% | 96.8% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.71 | 62.0 | 4.43e-01 | 100.0% | 76.9% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.70 | 55.0 | 5.79e-01 | 85.3% | 100.0% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.70 | 54.0 | 5.10e-01 | 89.3% | 69.2% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.70 | 61.0 | 5.66e-01 | 97.3% | 81.9% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 58.0 | 5.11e-01 | 93.3% | 62.7% |
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.69 | 58.0 | 3.86e-01 | 96.0% | 22.0% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.69 | 59.0 | 5.33e-01 | 97.3% | 70.0% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.67 | 51.0 | 5.45e-01 | 93.3% | 98.4% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 53.0 | 4.95e-01 | 94.7% | 67.3% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 57.0 | 5.44e-01 | 100.0% | 82.2% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.66 | 57.0 | 4.59e-01 | 100.0% | 48.3% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.66 | 54.0 | 4.64e-01 | 90.7% | 57.1% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.65 | 52.0 | 5.18e-01 | 94.7% | 89.5% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 50.0 | 4.97e-01 | 85.3% | 83.3% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 54.0 | 4.66e-01 | 100.0% | 72.6% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.59 | 50.0 | 5.08e-01 | 96.0% | 98.6% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 43.0 | 4.57e-01 | 93.3% | 100.0% |
| 2x6hA03 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.55 | 46.0 | 3.46e-01 | 96.0% | 39.5% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.54 | 44.0 | 4.49e-01 | 94.7% | 95.9% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 58691 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.86 | 78.0 | 6.40e-01 | 97.3% | 79.7% |
| 2636645 | 192.15.1.2 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r | 0.85 | 71.0 | 7.54e-01 | 89.3% | 98.5% |
| 3834430 | 3755.3.1.285 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A | 0.84 | 77.0 | 5.47e-01 | 97.3% | 54.5% |
| 3701245 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.84 | 74.0 | 6.46e-01 | 96.0% | 69.1% |
| 4086306 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.84 | 75.0 | 5.23e-01 | 97.3% | 54.2% |
| 4001189 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 76.0 | 4.57e-01 | 98.7% | 30.5% |
| 3704105 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 74.0 | 5.71e-01 | 97.3% | 51.2% |
| 4508528 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.83 | 74.0 | 6.21e-01 | 98.7% | 60.8% |
| 3385727 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 76.0 | 5.08e-01 | 100.0% | 69.6% |
| 4120406 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.83 | 73.0 | 6.38e-01 | 96.0% | 68.2% |
| 5067407 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.82 | 72.0 | 6.25e-01 | 94.7% | 64.5% |
| 3476064 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.82 | 72.0 | 6.11e-01 | 96.0% | 60.0% |
| 3428894 | 604.5.1.39 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF26581 | 0.82 | 75.0 | 5.99e-01 | 100.0% | 71.4% |
| 3598168 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.81 | 72.0 | 5.52e-01 | 97.3% | 45.5% |
| 3486312 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.81 | 71.0 | 6.06e-01 | 96.0% | 60.5% |
| 3702347 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 72.0 | 5.44e-01 | 97.3% | 42.9% |
| 4028291 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.81 | 72.0 | 4.40e-01 | 96.0% | 17.4% |
| 4316383 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 71.0 | 6.55e-01 | 97.3% | 76.8% |
| 3628940 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.80 | 71.0 | 6.17e-01 | 96.0% | 90.9% |
| 3266175 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.80 | 71.0 | 6.20e-01 | 100.0% | 74.8% |
| 3936511 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.80 | 65.0 | 3.94e-01 | 97.3% | 14.7% |
| 4120495 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.80 | 72.0 | 4.47e-01 | 100.0% | 26.3% |
| 1002194 | 192.23.1.1 ↗ | alpha bundles › Long alpha-hairpin › DUF683 › DUF683 › Rop-like | 0.80 | 67.0 | 6.85e-01 | 97.3% | 95.8% |
| 3176786 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.80 | 71.0 | 5.32e-01 | 97.3% | 42.9% |
| 1879027 | 244.1.1.6 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase | 0.80 | 70.0 | 4.37e-01 | 97.3% | 18.9% |
| 3355282 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.80 | 73.0 | 5.31e-01 | 100.0% | 71.1% |
| 3273923 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.79 | 71.0 | 4.35e-01 | 97.3% | 18.1% |
| 3876221 | 5.1.12.5 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › PERK and Ire1 luminal domains › KIF21A | 0.79 | 66.0 | 5.14e-01 | 97.3% | 43.9% |
| 3235839 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.79 | 68.0 | 5.20e-01 | 97.3% | 51.4% |
| 3574626 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 69.0 | 5.62e-01 | 98.7% | 54.3% |
| 5056871 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.78 | 69.0 | 4.49e-01 | 97.3% | 26.5% |
| 3184698 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.77 | 62.0 | 5.84e-01 | 97.3% | 72.2% |
| 185321 | 109.4.1.262 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_C | 0.77 | 68.0 | 4.67e-01 | 97.3% | 30.0% |
| 3918310 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.77 | 69.0 | 6.20e-01 | 100.0% | 77.1% |
| 4027748 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.76 | 68.0 | 5.45e-01 | 100.0% | 57.2% |
| 3294437 | 5086.1.1.110 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA | 0.76 | 65.0 | 6.36e-01 | 94.7% | 97.5% |
| 4975739 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.75 | 66.0 | 4.18e-01 | 100.0% | 32.1% |
| 3938802 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.75 | 67.0 | 4.13e-01 | 100.0% | 61.4% |
| 3609437 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.74 | 65.0 | 5.35e-01 | 97.3% | 56.3% |
| 3760768 | 148.1.3.248 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A | 0.74 | 64.0 | 5.04e-01 | 97.3% | 47.5% |
| 3339561 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.74 | 64.0 | 5.80e-01 | 96.0% | 81.0% |
| 3270696 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.74 | 63.0 | 5.67e-01 | 96.0% | 69.5% |
| 3735607 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.73 | 62.0 | 6.13e-01 | 94.7% | 88.7% |
| 3661101 | 3755.3.1.290 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PPI_helical | 0.73 | 63.0 | 5.00e-01 | 96.0% | 51.0% |
| 3368307 | 3291.1.1.119 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › NET2A | 0.73 | 63.0 | 5.77e-01 | 97.3% | 75.0% |
| 4022378 | 3860.1.1.0 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm | 0.73 | 64.0 | 4.35e-01 | 100.0% | 41.8% |
| 5033276 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.73 | 67.0 | 5.26e-01 | 100.0% | 98.7% |
| 3831 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.73 | 63.0 | 5.68e-01 | 96.0% | 71.6% |
| 3571433 | 3939.1.1.220 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › KIF21A | 0.72 | 62.0 | 4.91e-01 | 97.3% | 47.5% |
| 3181323 | 192.29.1.296 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ceramidase | 0.72 | 61.0 | 5.09e-01 | 96.0% | 54.5% |
| 3509997 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.71 | 61.0 | 4.51e-01 | 98.7% | 37.6% |
| 3435097 | 4177.1.1.11 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632 | 0.71 | 59.0 | 4.12e-01 | 96.0% | 27.5% |
| 4116939 | 2004.1.1.525 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_27, SbcC_Walker_B | 0.70 | 61.0 | 3.67e-01 | 96.0% | 29.5% |
| 5012108 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 61.0 | 4.09e-01 | 100.0% | 54.4% |
| 4453815 | 192.12.1.1 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › Prok-TraM | 0.70 | 61.0 | 5.67e-01 | 100.0% | 81.1% |
| 3990182 | 3922.1.1.226 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Fy-3 | 0.69 | 58.0 | 5.08e-01 | 94.7% | 66.1% |
| 5000824 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.66 | 57.0 | 4.64e-01 | 98.7% | 52.4% |
D3
medium
residues 220-332
Domain cluster:
rep: envelope_glycoprotein_M__YP_009176930__Testudinid_alphaherpesvirus_3__2560801__D231-337
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 99.2 | 3.70e-28 | 99.1% | 34.6% |