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kinase
Euk-VirCricetid_gammaherpesvirus_2
kinase__YP_004207873__Cricetid_gammaherpesvirus_2__1605972
Identity
- Accession:
- YP_004207873 ↗
- Protein ID:
- kinase
- Kingdom:
- euk
Quality
80.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Cricetid_gammaherpesvirus_2
TaxID: 1605972
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 59-169_233-259
Domain cluster:
rep: ORF36__YP_438159__Ovine_gammaherpesvirus_2__10398__D54-226
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6bfnA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.69 | 45.0 | 5.41e-01 | 77.5% | 98.9% |
| 4qnyA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.62 | 43.0 | 4.67e-01 | 75.4% | 83.2% |
| 4crsA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.62 | 45.0 | 4.59e-01 | 74.6% | 91.8% |
| 1a10I00 | 3.30.10.10 | Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › Trypsin Inhibitor V, subunit A | 0.61 | 20.0 | 2.94e-01 | 92.0% | 60.3% |
| 3nynA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.58 | 43.0 | 4.29e-01 | 78.3% | 73.5% |
| 3w0eA00 | 3.30.10.10 | Alpha Beta › 2-Layer Sandwich › Trypsin Inhibitor V; Chain A › Trypsin Inhibitor V, subunit A | 0.57 | 20.0 | 2.79e-01 | 92.8% | 61.8% |
| 3va7A05 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.53 | 37.0 | 4.33e-01 | 74.6% | 99.0% |
| 3qugA00 | 2.60.40.1850 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.50 | 36.0 | 3.91e-01 | 79.7% | 90.3% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4030175 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.75 | 54.0 | 4.03e-01 | 73.9% | 59.4% |
| 3947242 | 206.1.1.14 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 | 0.75 | 57.0 | 4.13e-01 | 78.3% | 53.2% |
| 3442506 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.72 | 51.0 | 3.57e-01 | 72.5% | 40.7% |
| 3683109 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.72 | 51.0 | 3.58e-01 | 72.5% | 41.2% |
| 3606496 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.69 | 54.0 | 3.81e-01 | 81.9% | 59.6% |
| 3716840 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.68 | 53.0 | 3.71e-01 | 81.2% | 51.7% |
| 3265965 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.68 | 54.0 | 3.71e-01 | 84.1% | 86.3% |
| 3718549 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.66 | 52.0 | 3.76e-01 | 81.2% | 57.6% |
| 3615135 | 206.1.1.74 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr | 0.66 | 51.0 | 3.60e-01 | 81.2% | 50.8% |
| 3217221 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.66 | 52.0 | 4.10e-01 | 81.9% | 96.6% |
| 4337982 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.65 | 51.0 | 3.74e-01 | 81.9% | 68.3% |
| 3275983 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.65 | 50.0 | 3.86e-01 | 80.4% | 92.8% |
| 4263654 | 206.1.1.73 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, APH | 0.65 | 60.0 | 4.36e-01 | 97.1% | 65.7% |
| None | — | 0.65 | 47.0 | 4.13e-01 | 75.4% | 100.0% | |
| 3609530 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.64 | 53.0 | 3.84e-01 | 87.0% | 76.3% |
| 4048821 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.64 | 52.0 | 3.66e-01 | 86.2% | 55.7% |
| 3927695 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.64 | 51.0 | 3.84e-01 | 84.1% | 60.6% |
| 3367579 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.63 | 51.0 | 3.87e-01 | 85.5% | 62.3% |
| 3304155 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 51.0 | 3.82e-01 | 84.8% | 61.9% |
| 3437535 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 55.0 | 4.01e-01 | 92.8% | 60.0% |
| 3585647 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.62 | 49.0 | 3.70e-01 | 81.9% | 61.9% |
| 3647662 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.62 | 51.0 | 3.74e-01 | 86.2% | 55.9% |
| None | — | 0.62 | 52.0 | 3.88e-01 | 87.7% | 61.9% | |
| 3185940 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 46.0 | 3.64e-01 | 79.0% | 62.7% |
| 3180499 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 50.0 | 3.60e-01 | 85.5% | 66.9% |
| 3272987 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.61 | 48.0 | 3.80e-01 | 81.2% | 66.3% |
| 4998448 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.61 | 47.0 | 3.48e-01 | 82.6% | 64.7% |
| 3454500 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 53.0 | 3.89e-01 | 93.5% | 61.7% |
| 184277 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.60 | 48.0 | 3.65e-01 | 82.6% | 68.9% |
| 4486025 | 206.1.1.14 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 | 0.60 | 47.0 | 3.19e-01 | 82.6% | 60.8% |
| 2712923 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.60 | 47.0 | 4.61e-01 | 81.9% | 83.8% |
| 3299265 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.60 | 48.0 | 3.54e-01 | 84.8% | 85.8% |
| 5009936 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 46.0 | 3.41e-01 | 81.2% | 63.2% |
| 4136484 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.59 | 46.0 | 3.59e-01 | 81.9% | 64.1% |
| 3275585 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.58 | 47.0 | 3.67e-01 | 85.5% | 66.9% |
| 5006044 | 206.1.1.268 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF6206 | 0.58 | 46.0 | 3.57e-01 | 82.6% | 68.8% |
| 4945303 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.58 | 45.0 | 3.31e-01 | 79.7% | 66.3% |
| 148544 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.58 | 45.0 | 3.51e-01 | 82.6% | 69.4% |
| 3198542 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 40.0 | 3.22e-01 | 71.7% | 49.6% |
| 4004448 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.57 | 46.0 | 3.44e-01 | 84.8% | 57.3% |
| 3808906 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.56 | 52.0 | 3.80e-01 | 99.3% | 56.9% |
| 3183471 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.56 | 44.0 | 3.20e-01 | 81.2% | 60.9% |
| 3605142 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.56 | 49.0 | 3.66e-01 | 94.9% | 70.7% |
| 4527337 | 206.1.2.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › Ins_P5_2-kin | 0.55 | 41.0 | 3.30e-01 | 77.5% | 93.1% |
| 3198158 | 206.1.1.83 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1, PK_Tyr_Ser-Thr | 0.55 | 51.0 | 3.71e-01 | 99.3% | 65.8% |
| 3992291 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.55 | 52.0 | 3.88e-01 | 98.6% | 60.0% |
| 3834138 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.55 | 50.0 | 4.09e-01 | 100.0% | 94.1% |
| 3597791 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.54 | 50.0 | 3.85e-01 | 100.0% | 66.1% |
| 3221647 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.53 | 49.0 | 3.68e-01 | 97.8% | 68.9% |
| 3752372 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.52 | 48.0 | 3.63e-01 | 100.0% | 58.7% |
| None | — | 0.52 | 48.0 | 3.82e-01 | 99.3% | 60.5% | |
| 4442155 | 206.1.1.76 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1, Pkinase_fungal | 0.50 | 39.0 | 3.10e-01 | 81.9% | 63.9% |
D2
medium
residues 170-232_260-324
D3
medium
residues 325-431
Domain cluster:
rep: tegument_serine_threonine_protein_kinase__YP_010085911__Wood_mouse_herpesvirus__432370__D304-430
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1e7uA05 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.60 | 48.0 | 3.96e-01 | 85.0% | 79.6% |
| 3n00A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.58 | 43.0 | 3.67e-01 | 79.4% | 80.4% |
| 4xaiB02 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.58 | 42.0 | 3.44e-01 | 74.8% | 81.1% |
| 3qdkA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.57 | 41.0 | 3.11e-01 | 74.8% | 57.6% |
| 3ubcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 38.0 | 3.66e-01 | 72.0% | 71.8% |
| 3s6jE02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 32.0 | 3.94e-01 | 71.0% | 91.3% |
| 2a3qA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.54 | 37.0 | 3.72e-01 | 94.4% | 67.3% |
| 3pvlA03 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.52 | 38.0 | 3.75e-01 | 78.5% | 72.9% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4560471 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.67 | 53.0 | 4.93e-01 | 84.1% | 100.0% |
| 3989714 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.63 | 48.0 | 3.96e-01 | 83.2% | 56.6% |
| 4997328 | 3962.1.1.0 ↗ | alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit | 0.59 | 42.0 | 3.98e-01 | 74.8% | 85.4% |
| 4930579 | 5052.1.1.0 ↗ | alpha complex topology › Proton glutamate symport protein › Proton glutamate symport protein › Proton glutamate symport protein | 0.55 | 42.0 | 3.12e-01 | 81.3% | 91.9% |
| 3256828 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.55 | 38.0 | 3.80e-01 | 71.0% | 89.1% |
| 3600865 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 39.0 | 3.40e-01 | 82.2% | 47.6% |
| 4453461 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.51 | 42.0 | 3.38e-01 | 90.7% | 93.8% |
| 4026503 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 39.0 | 2.98e-01 | 83.2% | 49.5% |