←Back to structures
large_T_antigen
Euk-VirMW_polyomavirus
large_T_antigen__YP_006495789__MW_polyomavirus__1203539
Identity
- Accession:
- YP_006495789 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
85.6
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Deltapolyomavirus›
MW_polyomavirus
TaxID: 1203539
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-73
Domain cluster:
rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D2
high
residues 165-281
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02217.23 best | T_Ag_DNA_bind | 107.7 | 5.30e-31 | 76.1% | 92.5% |
D3
high
residues 292-376
Domain cluster:
rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 91.3 | 9.20e-26 | 100.0% | 19.4% |
D4
medium
residues 379-435_570-590
Domain cluster:
rep: large_T_antigen__YP_010087549__Deltapolyomavirus_canis__2170403__D425-483
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 34.9 | 1.20e-08 | 75.6% | 14.4% |
D5
medium
residues 436-569
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 207.7 | 4.20e-61 | 100.0% | 31.9% |
D6
medium
residues 591-651
Domain cluster:
rep: large_T_antigen__YP_009094187__Pan_troglodytes_verus_polyomavirus_1a__928211__D731-787
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 33.8 | 2.50e-08 | 98.4% | 12.7% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA02 | 1.20.1050.70 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3 | 0.99 | 87.0 | 6.69e-01 | 91.8% | 47.5% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 42.0 | 2.79e-01 | 75.4% | 94.8% |
| 3pdiA02 | 3.40.50.12380 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal | 0.55 | 46.0 | 3.09e-01 | 100.0% | 86.8% |
| 3q9oA02 | 3.90.1350.10 | Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain | 0.55 | 47.0 | 3.52e-01 | 100.0% | 75.4% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.54 | 46.0 | 3.37e-01 | 96.7% | 75.3% |
| 3qxzA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.52 | 42.0 | 4.29e-01 | 93.4% | 91.7% |
| 2fgeA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.51 | 42.0 | 2.90e-01 | 93.4% | 53.1% |