large_T_antigen

Euk-Vir

Alphapolyomavirus_septipanos

large_T_antigen__YP_007195293__Alphapolyomavirus_septipanos__1891739

Identity

82.7 mean pLDDT

Shotokuvirae› Cossaviricota› Papovaviricetes› Sepolyvirales› Polyomaviridae› Alphapolyomavirus› Alphapolyomavirus_septipanos

TaxID: 1891739

View cluster (129 members)

Download PDB Download Scores JSON

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-67

PDB

Domain cluster: rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77

D2 high residues 173-289

PDB

Domain cluster: rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02217.23 best	T_Ag_DNA_bind	89.7	2.20e-25	81.2%	94.7%

D3 high residues 304-388

PDB

Domain cluster: rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	98.0	8.30e-28	100.0%	19.7%

D4 medium residues 391-454_582-665

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	64.0	1.80e-17	58.1%	18.7%

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1svmA02	1.20.1050.70	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3	0.94	73.0	8.22e-01	94.6%	99.2%
3lvyE01	1.20.1290.10	Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like	0.55	40.0	3.84e-01	79.1%	66.7%
1n40A00	1.10.630.10	Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450	0.54	42.0	3.18e-01	84.5%	74.9%
1ileA03	1.10.730.10	Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1	0.52	40.0	3.71e-01	81.1%	73.3%
3gyuA00	1.10.565.10	Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor	0.51	37.0	3.21e-01	75.7%	71.1%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3683792	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.58	27.0	3.04e-01	84.5%	54.5%
4283760	1203.1.2.7 ↗	alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR	0.56	38.0	3.95e-01	70.3%	88.6%
4683248	5086.1.1.66 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR	0.54	38.0	3.97e-01	72.3%	88.6%
None	—		0.54	37.0	2.71e-01	70.3%	57.6%
3832907	192.18.1.0 ↗	alpha bundles › Long alpha-hairpin › MxiH-like › MxiH-like	0.54	41.0	2.80e-01	79.1%	62.5%
4030861	5051.1.1.10 ↗	alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2	0.52	37.0	2.68e-01	73.0%	62.2%

D5 medium residues 455-581

PDB

Domain cluster: rep: large_T_antigen__YP_009553187__Philantomba_monticola_polyomavirus_1__2170411__D436-450_495-593

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	162.7	2.00e-47	100.0%	30.0%