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large_T_antigen
Euk-VirAfrican_elephant_polyomavirus_1
large_T_antigen__YP_008603286__African_elephant_polyomavirus_1__1399914
Identity
- Accession:
- YP_008603286 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
84.6
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Betapolyomavirus›
African_elephant_polyomavirus_1
TaxID: 1399914
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-71
Domain cluster:
rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D2
high
residues 146-250
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02217.23 best | T_Ag_DNA_bind | 103.5 | 1.10e-29 | 82.9% | 89.4% |
D3
high
residues 281-358
Domain cluster:
rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 86.7 | 2.20e-24 | 100.0% | 17.8% |
D4
high
residues 397-592
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 285.9 | 7.60e-85 | 100.0% | 47.0% |
D5
medium
residues 359-396_593-632
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 29.7 | 4.40e-07 | 52.6% | 8.9% |
| PF06431.17 | Polyoma_lg_T_C | 26.2 | 5.10e-06 | 51.3% | 8.9% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA02 | 1.20.1050.70 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3 | 0.98 | 91.0 | 7.63e-01 | 96.2% | 100.0% |
| 4b94A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 44.0 | 3.70e-01 | 85.9% | 72.3% |
| 4c0eA01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 42.0 | 2.93e-01 | 80.8% | 30.4% |
| 8jpdG01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.54 | 44.0 | 3.65e-01 | 89.7% | 52.4% |