←Back to structures
large_T_antigen
Euk-VirPan_troglodytes_verus_polyomavirus_1a
large_T_antigen__YP_009094187__Pan_troglodytes_verus_polyomavirus_1a__928211
Identity
- Accession:
- YP_009094187 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
74.6
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Alphapolyomavirus›
Pan_troglodytes_verus_polyomavirus_1a
TaxID: 928211
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 320-416
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02217.23 best | T_Ag_DNA_bind | 92.9 | 2.20e-26 | 79.4% | 81.9% |
D2
high
residues 433-516
Domain cluster:
rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 80.4 | 1.90e-22 | 100.0% | 20.1% |
D3
high
residues 556-707
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 194.4 | 4.60e-57 | 99.3% | 33.8% |
| PF00519.24 | PPV_E1_C | 38.7 | 9.50e-10 | 96.7% | 37.7% |
D4
medium
residues 1-73
Domain cluster:
rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D5
medium
residues 731-787
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 29.5 | 5.10e-07 | 98.2% | 12.2% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA02 | 1.20.1050.70 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3 | 0.99 | 90.0 | 6.76e-01 | 94.7% | 45.8% |
| 3q9oA02 | 3.90.1350.10 | Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain | 0.55 | 46.0 | 3.41e-01 | 100.0% | 64.1% |
| 4efcA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.54 | 39.0 | 3.24e-01 | 84.2% | 82.6% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4933518 | 5065.1.1.1 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 | 0.52 | 40.0 | 2.64e-01 | 87.7% | 56.7% |
| 3489329 | 109.4.1.1164 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › zf-MYND | 0.52 | 43.0 | 2.89e-01 | 98.2% | 29.8% |
| 5083422 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.51 | 39.0 | 2.82e-01 | 96.5% | 81.4% |