large_T_antigen

Euk-Vir

Betapolyomavirus_mastomysis

large_T_antigen__YP_009111358__Betapolyomavirus_mastomysis__1891768

Identity

86.2 mean pLDDT

Shotokuvirae› Cossaviricota› Papovaviricetes› Sepolyvirales› Polyomaviridae› Betapolyomavirus› Betapolyomavirus_mastomysis

TaxID: 1891768

View cluster (129 members)

Download PDB Download Scores JSON

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-64

PDB

Domain cluster: rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77

D2 high residues 155-260

PDB

Domain cluster: rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02217.23 best	T_Ag_DNA_bind	110.3	8.20e-32	84.0%	94.7%

D3 high residues 282-363

PDB

Domain cluster: rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	109.8	2.20e-31	100.0%	19.7%

D4 medium residues 364-435_563-642

PDB

Domain cluster: rep: large_T_antigen__YP_007195293__Alphapolyomavirus_septipanos__1891739__D391-454_582-665

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	51.5	1.10e-13	52.6%	18.0%
PF06431.17	Polyoma_lg_T_C	53.3	3.10e-14	50.7%	16.6%

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1svmA02	1.20.1050.70	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3	0.97	74.0	8.45e-01	96.1%	100.0%
3beyD00	1.20.1290.10	Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like	0.58	31.0	3.79e-01	94.1%	80.9%
4o8sA02	1.20.58.1790	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › JHP933, helical tail domain	0.57	29.0	3.31e-01	88.2%	63.6%
3tjmA02	1.10.1470.20	Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › Fatty acid synthase; domain 2	0.53	25.0	3.14e-01	88.2%	72.2%
3na7A00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.51	35.0	3.07e-01	71.1%	100.0%
3lvyE01	1.20.1290.10	Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like	0.51	37.0	3.68e-01	82.9%	70.3%
7lb8B02	1.10.3470.10	Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC	0.51	40.0	3.19e-01	82.9%	85.8%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3248006	5050.1.1.4 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran	0.53	34.0	3.38e-01	86.8%	58.8%
3386205	131.1.1.0 ↗	alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like	0.52	36.0	3.52e-01	71.1%	74.9%
3796800	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.51	29.0	3.06e-01	70.4%	60.0%
3832912	6155.1.1.6 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921	0.51	37.0	3.12e-01	74.3%	83.5%

D5 medium residues 436-562

PDB

Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	227.4	4.40e-67	100.0%	30.2%