←Back to structures
large_T_antigen
Euk-VirYellow_baboon_polyomavirus_2
large_T_antigen__YP_009111370__Yellow_baboon_polyomavirus_2__1286214
Identity
- Accession:
- YP_009111370 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
81.5
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Betapolyomavirus›
Yellow_baboon_polyomavirus_2
TaxID: 1286214
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 142-258
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02217.23 best | T_Ag_DNA_bind | 126.9 | 5.40e-37 | 76.9% | 94.7% |
D2
high
residues 272-356
Domain cluster:
rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 174.1 | 6.50e-51 | 100.0% | 20.4% |
D3
medium
residues 1-71
Domain cluster:
rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D4
medium
residues 357-420_573-583
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 129.4 | 2.40e-37 | 92.0% | 15.6% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4alyB00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.58 | 44.0 | 3.30e-01 | 84.0% | 32.6% |
| 4gouA01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.53 | 41.0 | 3.37e-01 | 85.3% | 82.4% |
| 2af0A02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.52 | 33.0 | 3.29e-01 | 85.3% | 61.3% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3509888 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.57 | 41.0 | 3.18e-01 | 92.0% | 35.0% |
| 4819562 | 109.4.1.2126 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2, PPR_3, Rib_mS39_PPR | 0.56 | 37.0 | 2.79e-01 | 94.7% | 27.4% |
| 3742784 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.55 | 42.0 | 3.55e-01 | 82.7% | 97.7% |
| 3621947 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.55 | 38.0 | 3.50e-01 | 90.7% | 55.0% |
| 4944978 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.51 | 39.0 | 3.69e-01 | 100.0% | 67.8% |
| 3675882 | 2007.2.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II | 0.51 | 43.0 | 3.14e-01 | 96.0% | 71.6% |
D5
medium
residues 421-460_527-553
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 75.9 | 4.20e-21 | 61.2% | 9.6% |
| PF06431.17 | Polyoma_lg_T_C | 42.5 | 5.90e-11 | 41.8% | 6.2% |
CATH (57)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2r2aA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.81 | 73.0 | 5.22e-01 | 100.0% | 80.0% |
| 1gm5A04 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.75 | 68.0 | 4.79e-01 | 100.0% | 78.4% |
| 7tjhE01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.75 | 63.0 | 4.63e-01 | 94.0% | 89.9% |
| 4wsiB03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.74 | 67.0 | 4.71e-01 | 100.0% | 62.9% |
| 3cm0A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 64.0 | 4.67e-01 | 100.0% | 62.5% |
| 1cjmA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 63.0 | 4.40e-01 | 100.0% | 35.9% |
| 3crmA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 64.0 | 4.92e-01 | 100.0% | 80.9% |
| 3qktD01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 64.0 | 4.09e-01 | 100.0% | 90.3% |
| 3a00A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.70 | 59.0 | 5.34e-01 | 100.0% | 68.5% |
| 3tauA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.69 | 59.0 | 4.68e-01 | 100.0% | 47.4% |
| 3vpbA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.69 | 52.0 | 4.56e-01 | 95.5% | 54.5% |
| 7l4aA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.69 | 61.0 | 4.23e-01 | 98.5% | 67.1% |
| 1z8fA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.69 | 59.0 | 4.86e-01 | 100.0% | 52.9% |
| 2zpaA01 | 3.40.50.11040 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.68 | 57.0 | 4.23e-01 | 95.5% | 69.8% |
| 6qj2A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 59.0 | 3.73e-01 | 100.0% | 87.9% |
| 2fh5B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 60.0 | 4.26e-01 | 98.5% | 43.6% |
| 2cxxA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 58.0 | 4.22e-01 | 98.5% | 50.0% |
| 1xjcA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.65 | 58.0 | 4.49e-01 | 98.5% | 79.2% |
| 4b3xA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.64 | 57.0 | 4.22e-01 | 100.0% | 47.7% |
| 5izlA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 56.0 | 4.03e-01 | 100.0% | 50.5% |
| 4gx0B04 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.61 | 54.0 | 4.33e-01 | 98.5% | 73.3% |
| 5di3B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 54.0 | 3.84e-01 | 100.0% | 38.7% |
| 3i6dA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.60 | 53.0 | 4.04e-01 | 100.0% | 86.0% |
| 2a3nA01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.59 | 53.0 | 3.98e-01 | 100.0% | 64.2% |
| 3hdvB00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.59 | 52.0 | 4.27e-01 | 100.0% | 67.5% |
| 2b4aA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.59 | 52.0 | 4.34e-01 | 100.0% | 85.3% |
| 3breB01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 52.0 | 4.06e-01 | 100.0% | 62.2% |
| 2z04A01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 50.0 | 4.54e-01 | 95.5% | 72.2% |
| 3lovA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.58 | 51.0 | 3.93e-01 | 100.0% | 84.9% |
| 3cfyA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 52.0 | 4.17e-01 | 100.0% | 63.1% |
| 3c85A00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.58 | 51.0 | 3.95e-01 | 100.0% | 80.7% |
| 3lk7A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.58 | 49.0 | 4.53e-01 | 95.5% | 83.7% |
| 7lzaA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 50.0 | 4.17e-01 | 98.5% | 86.4% |
| 3a0uA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 51.0 | 4.25e-01 | 100.0% | 71.3% |
| 3al2A01 | 3.40.50.10190 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain | 0.57 | 38.0 | 3.19e-01 | 95.5% | 37.4% |
| 1lqtA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 49.0 | 3.47e-01 | 98.5% | 59.6% |
| 4q7eA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 50.0 | 4.12e-01 | 100.0% | 83.2% |
| 1hyhA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 50.0 | 3.96e-01 | 100.0% | 58.9% |
| 3pp8A02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 49.0 | 3.63e-01 | 98.5% | 49.7% |
| 3c3mA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 49.0 | 4.07e-01 | 98.5% | 85.4% |
| 8ajjA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.57 | 49.0 | 4.16e-01 | 98.5% | 83.3% |
| 3gpiA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.56 | 47.0 | 3.24e-01 | 98.5% | 54.2% |
| 2cxhA01 | 3.40.50.10480 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Brix domain | 0.56 | 45.0 | 3.41e-01 | 100.0% | 35.6% |
| 4isyA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.56 | 47.0 | 3.32e-01 | 100.0% | 52.6% |
| 5u25A02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.55 | 45.0 | 3.79e-01 | 94.0% | 79.5% |
| 3ezyA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.55 | 48.0 | 3.97e-01 | 98.5% | 78.3% |
| 4ew6A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.55 | 47.0 | 3.94e-01 | 98.5% | 73.3% |
| 4fflA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.55 | 47.0 | 4.24e-01 | 98.5% | 77.7% |
| 6o9aA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 42.0 | 3.65e-01 | 86.6% | 90.3% |
| 3waeB01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 46.0 | 3.64e-01 | 98.5% | 91.3% |
| 5dclA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 48.0 | 3.99e-01 | 100.0% | 69.2% |
| 3qy9B01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 46.0 | 3.73e-01 | 98.5% | 60.3% |
| 1o63A01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 45.0 | 3.80e-01 | 98.5% | 71.9% |
| 3bioB01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 46.0 | 3.47e-01 | 100.0% | 47.5% |
| 1j4aA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 45.0 | 3.31e-01 | 98.5% | 45.9% |
| 1xdwA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.52 | 44.0 | 3.24e-01 | 98.5% | 45.2% |
| 6rqaA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 42.0 | 3.28e-01 | 97.0% | 47.6% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3211713 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.83 | 73.0 | 5.67e-01 | 95.5% | 77.0% |
| 5027420 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.76 | 64.0 | 4.03e-01 | 94.0% | 39.9% |
| 4421892 | 3949.1.1.1 ↗ | alpha arrays › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › IPPT | 0.75 | 67.0 | 4.57e-01 | 100.0% | 57.8% |
| 4225510 | 3949.1.1.1 ↗ | alpha arrays › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › IPPT | 0.75 | 66.0 | 4.56e-01 | 100.0% | 60.3% |
| 3894021 | 2004.1.1.50 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin | 0.74 | 66.0 | 4.60e-01 | 100.0% | 56.4% |
| 5047074 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.74 | 66.0 | 4.10e-01 | 100.0% | 90.8% |
| 4616598 | 2004.1.1.59 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CoaE | 0.72 | 64.0 | 4.48e-01 | 100.0% | 86.0% |
| 4957252 | 2004.1.1.14 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU | 0.72 | 63.0 | 4.71e-01 | 97.0% | 51.9% |
| 3829245 | 2004.1.1.47 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › G-alpha | 0.71 | 65.0 | 4.24e-01 | 100.0% | 35.9% |
| 4561996 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.71 | 65.0 | 4.67e-01 | 100.0% | 51.1% |
| 4229039 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.71 | 64.0 | 4.75e-01 | 100.0% | 55.2% |
| 5045400 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.71 | 62.0 | 3.88e-01 | 100.0% | 89.4% |
| 3680270 | 2004.1.1.567 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 | 0.70 | 62.0 | 3.70e-01 | 100.0% | 90.3% |
| 4249598 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.70 | 63.0 | 4.68e-01 | 100.0% | 54.7% |
| 3961426 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 51.0 | 3.68e-01 | 100.0% | 27.4% |
| 4014882 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 62.0 | 3.94e-01 | 100.0% | 53.2% |
| 4376882 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 64.0 | 4.25e-01 | 100.0% | 42.9% |
| 4563139 | 2004.1.1.86 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › FeoB_N | 0.70 | 63.0 | 4.36e-01 | 100.0% | 42.9% |
| 5028706 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.69 | 61.0 | 4.78e-01 | 100.0% | 69.7% |
| 4999558 | 2004.1.1.16 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf | 0.68 | 61.0 | 4.40e-01 | 100.0% | 51.9% |
| 4516442 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.68 | 61.0 | 4.56e-01 | 100.0% | 55.8% |
| 4125989 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.67 | 61.0 | 4.52e-01 | 98.5% | 56.9% |
| 4024115 | 2004.1.1.132 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DLIC | 0.67 | 60.0 | 3.96e-01 | 100.0% | 37.5% |
| 3255978 | 2004.1.1.47 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › G-alpha | 0.67 | 60.0 | 4.11e-01 | 100.0% | 32.9% |
| 4982187 | 2004.1.1.51 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sulfotransfer_1 | 0.67 | 58.0 | 4.27e-01 | 100.0% | 50.3% |
| 4025647 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.66 | 60.0 | 4.33e-01 | 100.0% | 50.0% |
| 3494888 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.66 | 60.0 | 4.08e-01 | 100.0% | 55.2% |
| 4530056 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.66 | 59.0 | 4.34e-01 | 100.0% | 50.6% |
| 3542523 | 2004.1.1.122 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IIGP | 0.66 | 59.0 | 4.35e-01 | 100.0% | 68.0% |
| 4143587 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.66 | 59.0 | 4.21e-01 | 100.0% | 46.0% |
| 4175296 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.66 | 60.0 | 4.12e-01 | 100.0% | 46.4% |
| 3480123 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.66 | 61.0 | 4.20e-01 | 100.0% | 42.9% |
| 3933809 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.66 | 61.0 | 4.66e-01 | 100.0% | 62.1% |
| None | — | 0.65 | 57.0 | 3.75e-01 | 100.0% | 29.7% | |
| 3739790 | 2004.1.1.168 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRPRB | 0.65 | 59.0 | 4.16e-01 | 100.0% | 39.5% |
| 3895899 | 2004.1.1.118 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 | 0.64 | 59.0 | 4.18e-01 | 100.0% | 48.4% |
| 3888904 | 2004.1.1.118 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 | 0.63 | 57.0 | 3.95e-01 | 100.0% | 42.7% |
| 3250562 | 2004.1.1.164 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Roc | 0.63 | 57.0 | 4.06e-01 | 100.0% | 52.3% |
| 3844846 | 2004.1.1.118 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 | 0.63 | 57.0 | 3.96e-01 | 100.0% | 45.2% |
| 4584508 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.63 | 56.0 | 3.67e-01 | 100.0% | 33.0% |
| 3281192 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.61 | 54.0 | 3.94e-01 | 100.0% | 53.0% |
| 1200597 | 2003.1.1.28 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N | 0.61 | 54.0 | 4.28e-01 | 100.0% | 70.8% |
| 4367125 | 2003.1.8.4 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › MurD-like_N | 0.59 | 49.0 | 4.55e-01 | 95.5% | 72.9% |
| 3387164 | 2003.1.1.22 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA | 0.59 | 50.0 | 4.32e-01 | 97.0% | 61.0% |
| 3596857 | 7514.1.1.0 ↗ | a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.58 | 50.0 | 3.98e-01 | 97.0% | 76.1% |
| 4363238 | 2003.1.1.123 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DUF166 | 0.58 | 52.0 | 3.92e-01 | 100.0% | 68.1% |
| 3262396 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.57 | 51.0 | 3.90e-01 | 100.0% | 76.8% |
| 3598923 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 49.0 | 3.54e-01 | 98.5% | 58.0% |
| 3265097 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.56 | 49.0 | 3.28e-01 | 100.0% | 25.6% |
| 3729027 | 2003.1.1.20 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase | 0.56 | 48.0 | 3.12e-01 | 100.0% | 66.5% |
| 3262175 | 2003.1.5.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ | 0.55 | 47.0 | 2.96e-01 | 100.0% | 68.6% |
| 5020238 | 2003.1.10.21 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain › PylC-like_N | 0.55 | 47.0 | 3.90e-01 | 98.5% | 82.4% |
| 3387348 | 2003.1.8.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › PglD_N | 0.54 | 46.0 | 4.37e-01 | 100.0% | 78.8% |
| 3270973 | 2007.1.1.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › SNO | 0.54 | 47.0 | 3.27e-01 | 100.0% | 69.6% |
| 3666732 | 2003.1.2.29 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › NAD_binding_8 | 0.52 | 45.0 | 3.73e-01 | 97.0% | 92.5% |
| 3783003 | 2004.1.1.54 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin | 0.51 | 39.0 | 2.71e-01 | 91.0% | 77.7% |
D6
medium
residues 461-526
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 140.7 | 9.30e-41 | 100.0% | 15.8% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.93 | 89.0 | 6.49e-01 | 100.0% | 43.1% |
| 1tueD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.81 | 63.0 | 4.38e-01 | 100.0% | 27.2% |
| 6ks6q01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.56 | 38.0 | 2.59e-01 | 71.2% | 30.4% |
| 1grlB01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.56 | 38.0 | 2.64e-01 | 71.2% | 34.0% |
| 6ketA01 | 3.20.20.30 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain | 0.55 | 38.0 | 2.50e-01 | 74.2% | 35.1% |
| 1vypX00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.54 | 41.0 | 2.63e-01 | 100.0% | 15.5% |
| 6qpqB00 | 1.10.10.580 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E | 0.54 | 43.0 | 4.06e-01 | 87.9% | 88.9% |
| 3c7aA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 42.0 | 3.07e-01 | 100.0% | 28.8% |
| 2i7gB00 | 3.20.20.30 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain | 0.51 | 43.0 | 2.78e-01 | 100.0% | 24.9% |
| 3m8eA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 39.0 | 3.49e-01 | 87.9% | 73.3% |
| 7a6pB01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.50 | 40.0 | 3.22e-01 | 89.4% | 71.0% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2482197 | 2004.1.1.142 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Polyoma_lg_T_C | 0.93 | 89.0 | 6.81e-01 | 100.0% | 50.4% |
| 5081314 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.74 | 57.0 | 3.79e-01 | 100.0% | 21.2% |
| 3253892 | 2004.1.1.409 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 | 0.73 | 55.0 | 3.94e-01 | 100.0% | 27.7% |
| 4959586 | 2004.1.1.409 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 | 0.70 | 52.0 | 3.49e-01 | 100.0% | 19.4% |
| 4542391 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 43.0 | 2.98e-01 | 100.0% | 23.6% |
| 5039998 | 101.1.2.32 ↗ | alpha arrays › HTH › HTH › winged helix domain › Rrf2 | 0.53 | 41.0 | 3.37e-01 | 87.9% | 83.1% |
| 5025382 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 36.0 | 3.64e-01 | 100.0% | 76.5% |
D7
medium
residues 554-572_584-630
Domain cluster:
rep: large_T_antigen__YP_009094187__Pan_troglodytes_verus_polyomavirus_1a__928211__D731-787
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 100.9 | 1.10e-28 | 100.0% | 18.5% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA02 | 1.20.1050.70 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3 | 1.00 | 94.0 | 7.37e-01 | 97.0% | 63.6% |