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large_T_antigen

Euk-Vir

Bat_polyomavirus_6d

large_T_antigen__YP_009129300__Bat_polyomavirus_6d__1623686

Identity

Accession:
YP_009129300 ↗
Protein ID:
large_T_antigen
Kingdom:
euk

Quality

84.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 151-270
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02217.23 best T_Ag_DNA_bind 89.7 2.30e-25 77.5% 93.6%
D2 medium residues 1-67
PDB
D3 medium residues 294-393
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 126.3 2.10e-36 100.0% 23.5%
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1svmA01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.98 72.0 7.63e-01 75.0% 83.3%
2rekA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 36.0 3.03e-01 77.0% 35.5%
4i9oA00 1.10.246.20 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain 0.58 33.0 3.71e-01 90.0% 71.8%
2elcA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.55 26.0 3.13e-01 100.0% 64.2%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 34.0 3.39e-01 91.0% 57.4%
2pnqA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.52 40.0 2.73e-01 83.0% 25.4%
3n00A00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 44.0 3.66e-01 96.0% 65.8%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.51 33.0 3.18e-01 100.0% 54.6%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4882224 8001.1.1.2 alpha arrays › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › Polyoma_lg_T_C 0.97 77.0 7.88e-01 81.0% 84.4%
3783238 5041.1.1.15 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Tmemb_170 0.55 35.0 3.39e-01 89.0% 55.7%
3528706 192.29.1.11 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.52 37.0 3.44e-01 100.0% 58.4%
3330826 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.52 36.0 3.80e-01 100.0% 80.0%
D4 medium residues 394-437_559-645
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 36.0 5.40e-09 66.4% 18.7%
PF06431.17 Polyoma_lg_T_C 40.4 2.50e-10 42.0% 10.3%
D5 medium residues 438-558
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 211.5 3.00e-62 100.0% 29.0%