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large_T_antigen
Euk-VirRattus_norvegicus_polyomavirus_1
large_T_antigen__YP_009158866__Rattus_norvegicus_polyomavirus_1__1679933
Identity
- Accession:
- YP_009158866 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
77.6
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Alphapolyomavirus›
Rattus_norvegicus_polyomavirus_1
TaxID: 1679933
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-68
Domain cluster:
rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D2
high
residues 279-390
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02217.23 best | T_Ag_DNA_bind | 112.9 | 1.30e-32 | 78.6% | 93.6% |
D3
high
residues 407-489
Domain cluster:
rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 80.5 | 1.70e-22 | 100.0% | 19.2% |
D4
medium
residues 490-552
Domain cluster:
rep: large_T_antigen__YP_010087549__Deltapolyomavirus_canis__2170403__D425-483
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 37.1 | 2.60e-09 | 100.0% | 15.6% |
D5
medium
residues 553-687
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 185.4 | 2.50e-54 | 99.3% | 30.2% |
D6
medium
residues 688-761
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 25.7 | 7.30e-06 | 100.0% | 16.8% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA02 | 1.20.1050.70 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3 | 0.98 | 95.0 | 7.82e-01 | 100.0% | 62.7% |
| 4xukA00 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.58 | 50.0 | 3.41e-01 | 98.6% | 99.3% |
| 2dodA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.52 | 35.0 | 3.43e-01 | 70.3% | 74.4% |
| 5t3wA00 | 1.20.120.1160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.50 | 36.0 | 3.06e-01 | 78.4% | 90.5% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.50 | 35.0 | 3.41e-01 | 75.7% | 63.5% |