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large_T_antigen
Euk-VirThetapolyomavirus_trebernacchii
large_T_antigen__YP_009552745__Thetapolyomavirus_trebernacchii__2218588
Identity
- Accession:
- YP_009552745 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
74.9
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Thetapolyomavirus›
Thetapolyomavirus_trebernacchii
TaxID: 2218588
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 11-72
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1fafA00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.75 | 67.0 | 6.11e-01 | 96.8% | 82.3% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.68 | 55.0 | 4.32e-01 | 88.7% | 91.4% |
| 3besR03 | 6.10.140.1480 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 46.0 | 4.80e-01 | 71.0% | 94.6% |
| 4eqyA02 | 1.20.1180.10 | Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain | 0.67 | 47.0 | 4.61e-01 | 77.4% | 67.1% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.65 | 50.0 | 4.95e-01 | 100.0% | 77.6% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 44.0 | 4.20e-01 | 75.8% | 97.3% |
| 6nmgA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.62 | 52.0 | 3.18e-01 | 95.2% | 22.7% |
| 1nklA00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.62 | 42.0 | 3.93e-01 | 71.0% | 60.3% |
| 3tahA02 | 1.10.287.1770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 52.0 | 4.73e-01 | 98.4% | 76.1% |
| 1m12A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.61 | 41.0 | 3.84e-01 | 72.6% | 60.7% |
| 6fhpD00 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.61 | 46.0 | 4.63e-01 | 82.3% | 90.3% |
| 7y8uF01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.55 | 46.0 | 3.39e-01 | 100.0% | 55.9% |
| 3a1sA02 | 1.10.287.1770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 44.0 | 4.08e-01 | 100.0% | 83.0% |
| 1hciA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 45.0 | 3.60e-01 | 100.0% | 46.8% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3410825 | 109.40.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Hira | 0.76 | 59.0 | 4.37e-01 | 83.9% | 38.1% |
| 3933449 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.74 | 50.0 | 4.46e-01 | 71.0% | 83.3% |
| 3263335 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.68 | 46.0 | 4.31e-01 | 71.0% | 61.3% |
| 3238319 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 51.0 | 4.01e-01 | 82.3% | 68.5% |
| 4947059 | 7573.1.1.1 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran | 0.66 | 48.0 | 3.35e-01 | 77.4% | 24.0% |
| 3261605 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.64 | 44.0 | 4.06e-01 | 71.0% | 63.7% |
| 3192984 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.64 | 50.0 | 3.80e-01 | 88.7% | 75.6% |
| 3197884 | 327.11.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) | 0.63 | 48.0 | 4.80e-01 | 85.5% | 80.0% |
| 3991842 | 6171.1.1.0 ↗ | alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases | 0.63 | 49.0 | 3.68e-01 | 87.1% | 40.0% |
| 3898095 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.62 | 43.0 | 3.96e-01 | 74.2% | 57.6% |
| 3262 | 198.1.1.26 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › PF31278 | 0.62 | 42.0 | 3.93e-01 | 71.0% | 60.3% |
| 3209343 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.61 | 49.0 | 3.69e-01 | 88.7% | 77.4% |
| 3807124 | 2004.1.1.430 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn | 0.60 | 44.0 | 2.58e-01 | 80.6% | 28.3% |
| 3743020 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.60 | 47.0 | 3.38e-01 | 88.7% | 59.5% |
| 3942635 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.59 | 51.0 | 3.96e-01 | 100.0% | 75.9% |
| 3874269 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.57 | 50.0 | 4.07e-01 | 100.0% | 91.7% |
| 3975833 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.57 | 50.0 | 3.47e-01 | 100.0% | 43.8% |
| 3891338 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.56 | 49.0 | 3.38e-01 | 100.0% | 40.4% |
| 3598777 | 4156.1.1.0 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like | 0.56 | 48.0 | 3.44e-01 | 100.0% | 43.0% |
| 3585518 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.56 | 49.0 | 3.37e-01 | 100.0% | 40.5% |
| 4252806 | 2004.1.1.59 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CoaE | 0.56 | 42.0 | 3.07e-01 | 95.2% | 27.0% |
| 3702647 | 4156.1.1.0 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like | 0.55 | 46.0 | 2.71e-01 | 100.0% | 13.5% |
| 3522458 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.55 | 48.0 | 3.61e-01 | 100.0% | 56.2% |
| 3163669 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.55 | 48.0 | 3.33e-01 | 100.0% | 41.4% |
| 3779776 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.55 | 48.0 | 3.34e-01 | 100.0% | 42.9% |
| 3871115 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.55 | 47.0 | 3.25e-01 | 100.0% | 39.1% |
| 3787000 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.55 | 46.0 | 3.36e-01 | 100.0% | 43.6% |
| 3646394 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.55 | 47.0 | 3.75e-01 | 100.0% | 74.8% |
| 3860220 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.55 | 45.0 | 3.34e-01 | 100.0% | 43.1% |
| 4040812 | 101.1.2.70 ↗ | alpha arrays › HTH › HTH › winged helix domain › PqqD | 0.55 | 44.0 | 4.01e-01 | 93.5% | 79.8% |
| 3729996 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.54 | 46.0 | 3.22e-01 | 100.0% | 40.0% |
| 3786077 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.54 | 46.0 | 3.14e-01 | 100.0% | 32.4% |
| 3794203 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.54 | 45.0 | 4.08e-01 | 93.5% | 81.2% |
| 3369428 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.51 | 44.0 | 4.26e-01 | 95.2% | 84.3% |
| 4029785 | 2486.1.1.1 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ECH_1 | 0.50 | 43.0 | 2.84e-01 | 100.0% | 87.1% |
D2
high
residues 90-199
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
D3
high
residues 332-524
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 142.0 | 3.70e-41 | 99.0% | 37.6% |
| PF00519.24 | PPV_E1_C | 33.0 | 5.10e-08 | 82.4% | 39.1% |
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.95 | 74.0 | 8.35e-01 | 80.3% | 100.0% |
| 1tueD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.77 | 69.0 | 6.80e-01 | 100.0% | 90.1% |
| 1u0jA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.74 | 64.0 | 6.31e-01 | 99.5% | 85.0% |
| 3m6aA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.74 | 54.0 | 6.13e-01 | 83.4% | 96.7% |
| 5ywwA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.69 | 47.0 | 4.78e-01 | 85.0% | 70.6% |
| 1fnnA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.69 | 54.0 | 5.69e-01 | 81.3% | 100.0% |
| 7wd3A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 53.0 | 5.72e-01 | 81.3% | 100.0% |
| 7w42B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 53.0 | 5.53e-01 | 83.9% | 89.1% |
| 7swlB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 53.0 | 5.73e-01 | 81.9% | 100.0% |
| 1sxjA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 55.0 | 5.68e-01 | 85.0% | 96.1% |
| 2zpaA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.64 | 43.0 | 5.08e-01 | 72.5% | 95.6% |
| 2qenA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 51.0 | 5.06e-01 | 85.5% | 100.0% |
| 3crvA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 49.0 | 4.50e-01 | 86.5% | 100.0% |
| 3mwyW04 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 43.0 | 3.85e-01 | 86.0% | 53.2% |
| 2vl7A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 47.0 | 4.99e-01 | 82.4% | 100.0% |
| 6b4kB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 39.0 | 4.10e-01 | 80.8% | 74.7% |
| 4w7sA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 38.0 | 3.92e-01 | 80.8% | 67.7% |
| 7a8rA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 39.0 | 3.91e-01 | 82.4% | 65.3% |
| 1wp9A02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 39.0 | 4.34e-01 | 81.9% | 87.2% |
| 2eyqA04 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 39.0 | 3.57e-01 | 80.8% | 52.2% |
| 2xveA02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.56 | 28.0 | 3.59e-01 | 74.6% | 84.0% |
| 1m6nA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 39.0 | 4.07e-01 | 81.9% | 77.0% |
| 4dadA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 31.0 | 3.69e-01 | 72.0% | 84.4% |
| 5gxdA01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.53 | 47.0 | 3.47e-01 | 95.9% | 49.0% |
| 1c4oA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 40.0 | 4.43e-01 | 83.9% | 98.0% |
| 7pcrA01 | 3.40.50.10710 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Metallo-hydrolase/oxidoreductase | 0.52 | 40.0 | 4.43e-01 | 79.3% | 100.0% |
| 2cb0A02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.52 | 37.0 | 4.12e-01 | 95.9% | 93.4% |
| 4qdiA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.52 | 41.0 | 3.93e-01 | 84.5% | 91.7% |
| 1pg4A01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.51 | 46.0 | 3.43e-01 | 99.0% | 47.6% |
| 2amlA02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.51 | 36.0 | 4.09e-01 | 95.9% | 97.3% |
| 3g68A02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.50 | 36.0 | 4.05e-01 | 96.9% | 97.2% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2810781 | 8001.1.1.1 ↗ | alpha arrays › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › PPV_E1_C | 0.81 | 72.0 | 6.84e-01 | 100.0% | 80.5% |
| 5011495 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.80 | 64.0 | 6.38e-01 | 87.6% | 80.0% |
| 5056933 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.79 | 53.0 | 6.27e-01 | 83.4% | 97.0% |
| 4926850 | 2004.1.1.22 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sigma54_activat | 0.78 | 57.0 | 6.37e-01 | 85.0% | 92.9% |
| 3938925 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.74 | 53.0 | 5.90e-01 | 83.9% | 91.0% |
| 5081314 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.74 | 67.0 | 6.00e-01 | 99.5% | 71.2% |
| 3253892 | 2004.1.1.409 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 | 0.73 | 67.0 | 6.75e-01 | 100.0% | 95.9% |
| 5017850 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 53.0 | 5.97e-01 | 85.0% | 97.3% |
| 4931926 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 68.0 | 5.66e-01 | 100.0% | 67.6% |
| None | — | 0.72 | 55.0 | 6.08e-01 | 83.4% | 97.4% | |
| 3479645 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 54.0 | 5.58e-01 | 76.7% | 88.9% |
| 4941940 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.72 | 60.0 | 5.96e-01 | 92.2% | 84.0% |
| 4375031 | 2004.1.1.415 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA, RuvB_N | 0.71 | 56.0 | 5.98e-01 | 86.0% | 91.8% |
| 4506764 | 2004.1.1.425 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA, DUF815 | 0.71 | 55.0 | 6.04e-01 | 84.5% | 96.2% |
| 4931959 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.71 | 61.0 | 5.95e-01 | 92.2% | 83.4% |
| 4324606 | 2004.1.1.155 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_3 | 0.70 | 65.0 | 6.13e-01 | 97.9% | 84.8% |
| 4943098 | 2004.1.1.1214 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › RCF1-5-like_lid | 0.70 | 59.0 | 5.82e-01 | 92.2% | 82.9% |
| 3839744 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 64.0 | 5.66e-01 | 96.4% | 78.5% |
| 3924464 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.69 | 52.0 | 5.87e-01 | 82.9% | 100.0% |
| 4370162 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.69 | 45.0 | 5.38e-01 | 77.7% | 97.7% |
| 3290153 | 2004.1.1.156 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 | 0.69 | 60.0 | 6.11e-01 | 91.7% | 94.7% |
| 4542391 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.68 | 54.0 | 4.96e-01 | 82.9% | 65.6% |
| 5013281 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.68 | 63.0 | 5.50e-01 | 100.0% | 84.6% |
| 3952423 | 2004.1.1.339 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF3631 | 0.68 | 61.0 | 5.46e-01 | 97.4% | 69.8% |
| 3186345 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.67 | 53.0 | 5.49e-01 | 82.9% | 93.0% |
| 3505081 | 2004.1.1.98 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad17 | 0.67 | 54.0 | 5.47e-01 | 85.0% | 96.9% |
| 3597853 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.66 | 51.0 | 5.45e-01 | 84.5% | 92.7% |
| 4968232 | 2004.1.1.66 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase_2 | 0.66 | 57.0 | 5.20e-01 | 90.7% | 82.4% |
| 3605779 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.66 | 53.0 | 5.39e-01 | 83.4% | 92.1% |
| 3271689 | 2004.1.1.98 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad17 | 0.66 | 53.0 | 4.23e-01 | 84.5% | 50.3% |
| 5027337 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 44.0 | 5.23e-01 | 77.7% | 100.0% |
| 3465680 | 2004.1.1.56 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC | 0.64 | 52.0 | 5.34e-01 | 84.5% | 96.8% |
| 4955343 | 2004.1.1.196 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 | 0.62 | 49.0 | 5.12e-01 | 81.9% | 100.0% |
| 4029333 | 2004.1.1.232 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEXQc_Suv3 | 0.61 | 42.0 | 3.48e-01 | 71.0% | 46.9% |
| 5061376 | 2004.1.1.1200 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF835 | 0.60 | 47.0 | 5.03e-01 | 81.9% | 99.4% |
| 3600081 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.60 | 43.0 | 4.04e-01 | 85.5% | 60.9% |
| 4199200 | 2004.1.1.24 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C | 0.60 | 42.0 | 3.84e-01 | 86.0% | 52.8% |
| 4966314 | 2004.1.1.1217 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF7125 | 0.58 | 51.0 | 4.84e-01 | 92.7% | 91.7% |
| 3339398 | 2004.1.1.240 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Utp25_C | 0.58 | 40.0 | 4.08e-01 | 81.3% | 71.9% |
| 3991056 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 50.0 | 3.79e-01 | 91.7% | 89.9% |
| 3601193 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 46.0 | 4.20e-01 | 84.5% | 93.8% |
| 3404782 | 2004.1.1.240 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Utp25_C | 0.55 | 40.0 | 4.02e-01 | 80.8% | 72.3% |
| 3509126 | 2004.1.1.240 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Utp25_C | 0.55 | 39.0 | 3.97e-01 | 81.3% | 72.2% |
| 4425288 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 46.0 | 3.05e-01 | 88.1% | 42.1% |
| 4100828 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 42.0 | 3.29e-01 | 81.9% | 41.9% |
| 4265947 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.54 | 44.0 | 3.92e-01 | 85.0% | 94.3% |
| 4206314 | 2004.1.1.72 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IPT | 0.53 | 38.0 | 3.57e-01 | 74.6% | 59.6% |
| 3877172 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.52 | 40.0 | 3.98e-01 | 79.3% | 85.3% |
| 3248065 | 323.1.1.20 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding,ACAS_N | 0.52 | 46.0 | 3.40e-01 | 95.9% | 49.7% |
| 3739730 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.52 | 35.0 | 3.73e-01 | 99.0% | 76.0% |
| 3482984 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.52 | 40.0 | 3.76e-01 | 79.3% | 86.1% |
| 3641973 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.50 | 45.0 | 3.31e-01 | 97.4% | 53.3% |
D4
medium
residues 220-238_256-305
Domain cluster:
rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA01 | 1.10.10.510 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain | 0.87 | 83.0 | 7.46e-01 | 100.0% | 85.6% |
| 3bjdA01 | 1.10.1240.20 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain | 0.67 | 34.0 | 3.18e-01 | 100.0% | 39.8% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.67 | 40.0 | 3.36e-01 | 100.0% | 36.2% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 35.0 | 3.46e-01 | 95.7% | 50.0% |
| 4g1tA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 32.0 | 3.39e-01 | 97.1% | 57.4% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.60 | 39.0 | 4.21e-01 | 100.0% | 78.0% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.59 | 36.0 | 3.66e-01 | 97.1% | 62.1% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.59 | 47.0 | 3.92e-01 | 100.0% | 49.6% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 37.0 | 3.58e-01 | 100.0% | 57.1% |
| 3d2eA06 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 38.0 | 3.26e-01 | 100.0% | 40.7% |
| 2vxdA00 | 1.10.10.2100 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Nucleophosmin, C-terminal domain | 0.59 | 35.0 | 3.80e-01 | 84.1% | 74.1% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 34.0 | 3.30e-01 | 95.7% | 51.2% |
| 3eslA01 | 1.20.58.2070 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 35.0 | 3.49e-01 | 98.6% | 57.3% |
| 1bgwA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.56 | 47.0 | 4.18e-01 | 100.0% | 93.6% |
| 2cazD00 | 6.10.140.820 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 32.0 | 3.40e-01 | 100.0% | 65.0% |
| 2r18A02 | 1.10.8.880 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Birnavirus VP3 protein, domain 2 | 0.55 | 32.0 | 3.41e-01 | 88.4% | 66.1% |
| 3deeA01 | 1.10.150.690 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 | 0.54 | 32.0 | 3.07e-01 | 82.6% | 46.5% |
| 6cgvM01 | 1.20.120.1500 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pre-hexon-linking protein IIIa | 0.54 | 44.0 | 3.64e-01 | 94.2% | 95.5% |
| 3ilkA02 | 1.10.8.590 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.52 | 43.0 | 4.36e-01 | 89.9% | 92.6% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.51 | 39.0 | 3.74e-01 | 87.0% | 69.1% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 45.0 | 3.65e-01 | 100.0% | 71.6% |
| 1hbkA00 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.50 | 39.0 | 3.68e-01 | 94.2% | 68.5% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3616358 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.60 | 34.0 | 3.48e-01 | 97.1% | 54.3% |
| 5074726 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.60 | 34.0 | 3.22e-01 | 95.7% | 45.9% |
| 3169912 | 150.5.1.114 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PF29100 | 0.59 | 43.0 | 4.31e-01 | 100.0% | 75.7% |
| 3423402 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.58 | 37.0 | 3.43e-01 | 100.0% | 52.9% |
| 3254545 | 103.11.1.0 ↗ | alpha arrays › RuvA-C › RMI1 N-terminal helical domain-related › RMI1 N-terminal helical domain-related | 0.58 | 33.0 | 3.60e-01 | 87.0% | 69.1% |
| 3166324 | 148.1.3.334 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF27180 | 0.56 | 45.0 | 3.81e-01 | 89.9% | 52.5% |
| 3588719 | 564.1.1.0 ↗ | alpha arrays › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors | 0.55 | 40.0 | 4.16e-01 | 100.0% | 81.5% |
| 3788441 | 103.4.1.5 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 | 0.55 | 36.0 | 3.59e-01 | 100.0% | 62.7% |
| 3952621 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.55 | 43.0 | 4.32e-01 | 100.0% | 84.1% |
| 4057506 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.54 | 44.0 | 4.04e-01 | 88.4% | 78.9% |
| 3186746 | 145.1.1.0 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain | 0.53 | 32.0 | 3.31e-01 | 87.0% | 60.9% |
| 4024318 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 45.0 | 4.24e-01 | 95.7% | 85.9% |
| 5036523 | 1030.1.1.1 ↗ | alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Csm2_III-A | 0.52 | 44.0 | 3.71e-01 | 97.1% | 72.7% |
| 3668500 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.51 | 45.0 | 3.93e-01 | 98.6% | 74.3% |
| 5022013 | 632.7.1.61 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › BREX_BrxC_helical | 0.50 | 37.0 | 3.12e-01 | 79.7% | 60.8% |