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large_T_antigen
Euk-VirPhilantomba_monticola_polyomavirus_1
large_T_antigen__YP_009553187__Philantomba_monticola_polyomavirus_1__2170411
Identity
- Accession:
- YP_009553187 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
79.4
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Alphapolyomavirus›
Philantomba_monticola_polyomavirus_1
TaxID: 2170411
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-68
Domain cluster:
rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D2
high
residues 232-342
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02217.23 best | T_Ag_DNA_bind | 103.5 | 1.10e-29 | 75.7% | 90.4% |
D3
high
residues 352-434
Domain cluster:
rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 64.7 | 1.00e-17 | 98.8% | 19.4% |
D4
medium
residues 436-450_495-593
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 144.3 | 7.30e-42 | 97.4% | 24.0% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.89 | 82.0 | 7.21e-01 | 98.2% | 70.6% |
| 6xigA01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.59 | 41.0 | 3.08e-01 | 72.8% | 95.0% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.50 | 26.0 | 3.15e-01 | 88.6% | 73.4% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2482197 | 2004.1.1.142 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Polyoma_lg_T_C | 0.96 | 81.0 | 7.67e-01 | 86.8% | 75.6% |
| 3474509 | 2004.1.1.57 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Parvo_NS1 | 0.66 | 60.0 | 5.20e-01 | 97.4% | 88.8% |
| 4890930 | 148.1.3.397 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Dynein_C | 0.63 | 55.0 | 4.62e-01 | 93.9% | 84.1% |
| 3961108 | 2004.1.1.155 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_3 | 0.62 | 50.0 | 4.79e-01 | 86.8% | 74.6% |
| 4986568 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.61 | 56.0 | 4.28e-01 | 100.0% | 76.4% |
| 3609835 | 2004.1.1.211 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CLP1_P | 0.56 | 46.0 | 3.59e-01 | 87.7% | 78.8% |
| 3833268 | 2004.1.1.24 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C | 0.55 | 41.0 | 2.60e-01 | 78.1% | 35.6% |
| 4498368 | 2002.1.1.28 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PRAI | 0.55 | 40.0 | 3.39e-01 | 77.2% | 100.0% |
| 4162553 | 2004.1.1.211 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CLP1_P | 0.54 | 44.0 | 3.54e-01 | 87.7% | 64.5% |
| 5016262 | 2003.1.1.123 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DUF166 | 0.53 | 36.0 | 3.33e-01 | 87.7% | 54.5% |
D5
medium
residues 451-494_594-713
Domain cluster:
rep: large_T_antigen__YP_007195293__Alphapolyomavirus_septipanos__1891739__D391-454_582-665
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 102.2 | 4.50e-29 | 73.8% | 27.6% |