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large_T_antigen

Euk-Vir

Glis_glis_polyomavirus_1

large_T_antigen__YP_009553606__Glis_glis_polyomavirus_1__2170404

Identity

Accession:
YP_009553606 ↗
Protein ID:
large_T_antigen
Kingdom:
euk

Quality

85.6 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Sepolyvirales› Polyomaviridae› Betapolyomavirus› Glis_glis_polyomavirus_1

TaxID: 2170404

Cluster

View cluster (129 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-78
PDB
Domain cluster: rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00226.37 best DnaJ 29.6 8.50e-07 80.6% 84.1%
D2 high residues 153-257
PDB
Domain cluster: rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02217.23 best T_Ag_DNA_bind 103.0 1.50e-29 83.8% 93.6%
D3 high residues 279-362
PDB
Domain cluster: rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 74.1 1.50e-20 100.0% 19.9%
D4 medium residues 381-427_448-460_548-637
PDB
Domain cluster: rep: large_T_antigen__YP_007195293__Alphapolyomavirus_septipanos__1891739__D391-454_582-665
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 60.3 2.40e-16 60.0% 20.4%
PF06431.17 Polyoma_lg_T_C 32.1 8.60e-08 30.7% 9.8%
D5 medium residues 428-447_461-547
PDB
Domain cluster: rep: highly_derived_D5-like_helicase-primase__YP_003406787__Marseillevirus_marseillevirus__694581__D555-677
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 169.1 2.20e-49 100.0% 28.5%
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1svmA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.97 95.0 8.12e-01 100.0% 78.4%
1tueD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.78 73.0 5.79e-01 100.0% 55.0%
4zpxA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 62.0 4.75e-01 100.0% 79.4%
1g8pA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 59.0 4.80e-01 100.0% 81.4%
2qg6A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 52.0 4.32e-01 100.0% 53.8%
4i1sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 40.0 3.97e-01 100.0% 69.8%
2b7oA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 47.0 3.41e-01 99.1% 90.3%
5u4qB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 46.0 3.38e-01 94.4% 76.6%
5yjwA00 3.50.50.100 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › 0.54 41.0 2.72e-01 81.3% 21.8%
2i7gB00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.54 44.0 3.13e-01 89.7% 65.8%
8b73B01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.54 47.0 3.40e-01 99.1% 97.8%
3u7vA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 47.0 3.27e-01 99.1% 93.3%
1adoA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 43.0 3.04e-01 89.7% 65.3%
3afmB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 44.0 3.51e-01 94.4% 89.7%
6ketA01 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.53 43.0 3.10e-01 91.6% 63.5%
7bobA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 42.0 2.93e-01 86.0% 36.1%
2p5yA02 3.90.25.10 Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1 0.52 30.0 3.06e-01 70.1% 55.0%
1rhcA00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.52 43.0 3.08e-01 91.6% 65.8%
2c83A02 3.40.50.11110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sialyltransferase, C-terminal GT-B Rossman nucleotide-binding domain 0.51 38.0 3.29e-01 80.4% 66.5%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2482197 2004.1.1.142 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Polyoma_lg_T_C 0.97 95.0 8.67e-01 100.0% 91.6%
2810781 8001.1.1.1 ↗ alpha arrays › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › N-terminal domain of large tumor antigen › PPV_E1_C 0.82 78.0 5.92e-01 100.0% 50.2%
5011495 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.75 70.0 5.55e-01 100.0% 56.5%
5081314 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.73 68.0 5.01e-01 100.0% 43.8%
3253892 2004.1.1.409 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.73 68.0 5.49e-01 100.0% 55.4%
3595524 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.73 67.0 4.70e-01 100.0% 81.6%
3954608 2004.1.1.409 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.72 66.0 4.92e-01 100.0% 45.4%
5029777 2004.1.1.409 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.72 66.0 4.94e-01 100.0% 45.1%
4959586 2004.1.1.409 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.72 65.0 4.78e-01 100.0% 42.3%
5022020 2004.1.1.409 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.71 64.0 4.78e-01 100.0% 45.3%
3945876 2004.1.1.409 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.68 62.0 4.60e-01 100.0% 60.0%
None — 0.68 63.0 5.30e-01 100.0% 69.4%
3390911 138.1.1.13 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › AAA 0.66 61.0 4.22e-01 100.0% 37.6%
4542391 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 60.0 4.50e-01 100.0% 49.2%
3782903 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 56.0 4.76e-01 100.0% 79.4%
3610966 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 56.0 4.12e-01 100.0% 51.4%
3196949 2004.1.1.366 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N 0.61 56.0 4.61e-01 100.0% 70.5%
185753 2007.2.4.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Phosphoinositide phosphatase › SidF 0.58 46.0 2.83e-01 86.9% 27.2%
3315784 2002.1.1.32 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Oxidored_FMN 0.57 48.0 3.28e-01 92.5% 78.2%
4025422 2004.1.1.296 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MCM_bind 0.57 51.0 3.92e-01 100.0% 50.2%
5069444 2006.1.5.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Hist_deacetyl 0.57 49.0 3.48e-01 99.1% 53.1%
3905303 7529.1.1.11 ↗ a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › DUF2362 0.56 49.0 3.70e-01 98.1% 92.2%
3689453 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 46.0 3.96e-01 100.0% 57.6%
3319947 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 49.0 4.06e-01 100.0% 57.3%
3283271 2002.1.1.16 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Bac_luciferase 0.53 46.0 3.34e-01 100.0% 99.7%
3597294 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 46.0 3.23e-01 100.0% 93.3%
5046344 7573.1.1.0 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like 0.52 45.0 3.65e-01 100.0% 66.8%
4971136 7573.1.1.1 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran 0.52 44.0 3.27e-01 100.0% 46.2%
5051309 7601.1.1.2 ↗ a/b three-layered sandwiches › Lactate racemase N-terminal domain › Lactate racemase N-terminal domain › Lactate racemase N-terminal domain › DUF362 0.51 38.0 2.75e-01 81.3% 30.7%
2776404 2002.1.1.343 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Cellulase, Glyco_hydro_42 0.51 41.0 2.89e-01 88.8% 68.3%
4494461 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.50 40.0 3.22e-01 90.7% 65.8%