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large_T_antigen
Euk-VirPanthera_leo_polyomavirus_1
large_T_antigen__YP_009553612__Panthera_leo_polyomavirus_1__2170405
Identity
- Accession:
- YP_009553612 ↗
- Protein ID:
- large_T_antigen
- Kingdom:
- euk
Quality
83.8
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Sepolyvirales›
Polyomaviridae›
Betapolyomavirus›
Panthera_leo_polyomavirus_1
TaxID: 2170405
Cluster
View cluster (129 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-64
Domain cluster:
rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D2
high
residues 160-261
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02217.23 best | T_Ag_DNA_bind | 94.8 | 5.50e-27 | 83.3% | 90.4% |
D3
medium
residues 284-298_314-356
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 49.1 | 5.90e-13 | 100.0% | 11.5% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1svmA01 | 1.10.10.510 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain | 0.98 | 93.0 | 7.80e-01 | 100.0% | 81.1% |
| 1r5aA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 37.0 | 2.99e-01 | 96.6% | 36.0% |
D4
medium
residues 371-415_566-644
Domain cluster:
rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D403-422_572-647
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 49.4 | 4.60e-13 | 64.5% | 17.3% |
| PF06431.17 | Polyoma_lg_T_C | 41.0 | 1.60e-10 | 44.4% | 10.8% |
D5
medium
residues 416-565
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06431.17 best | Polyoma_lg_T_C | 260.1 | 5.00e-77 | 100.0% | 34.8% |