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large_T_antigen

Euk-Vir

Deltapolyomavirus_canis

large_T_antigen__YP_010087549__Deltapolyomavirus_canis__2170403

Identity

Accession:
YP_010087549 ↗
Protein ID:
large_T_antigen
Kingdom:
euk

Quality

81.1 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Sepolyvirales› Polyomaviridae› Deltapolyomavirus› Deltapolyomavirus_canis

TaxID: 2170403

Cluster

View cluster (129 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-68
PDB
Domain cluster: rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77
D2 high residues 213-321
PDB
Domain cluster: rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02217.23 best T_Ag_DNA_bind 101.4 4.90e-29 80.7% 92.5%
D3 high residues 341-424
PDB
Domain cluster: rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 81.1 1.10e-22 100.0% 19.7%
D4 medium residues 425-483
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 36.1 5.10e-09 100.0% 13.9%
D5 medium residues 484-543
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 94.1 1.30e-26 100.0% 14.4%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3e1sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 62.0 4.25e-01 98.3% 58.0%
1z6tA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 60.0 4.37e-01 100.0% 56.5%
3qtgA03 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.69 50.0 4.04e-01 78.3% 81.7%
2xgjB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 57.0 3.97e-01 98.3% 67.5%
2vk1A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.66 55.0 3.97e-01 98.3% 79.1%
1t6t200 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.62 46.0 3.92e-01 85.0% 86.4%
1toaA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.60 45.0 3.61e-01 85.0% 90.1%
7wgrA02 3.40.50.12470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 50.0 3.35e-01 98.3% 71.3%
1oywA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 48.0 3.88e-01 98.3% 77.3%
3hh8A02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.58 44.0 3.57e-01 86.7% 87.0%
7apeB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.56 44.0 3.24e-01 90.0% 64.1%
3mb5A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 42.0 3.02e-01 83.3% 85.5%
1wjwA01 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.55 41.0 3.75e-01 85.0% 76.5%
5f33A03 3.40.50.10800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NadA-like 0.54 39.0 3.60e-01 81.7% 92.9%
3kd6A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.54 39.0 2.62e-01 83.3% 96.7%
4eqsA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 39.0 3.13e-01 85.0% 90.9%
3v7eA00 3.30.1330.30 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 0.52 35.0 3.31e-01 71.7% 74.1%
1xtiA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 42.0 3.25e-01 100.0% 36.0%
3oy2A02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.51 40.0 2.81e-01 91.7% 88.4%
5h66A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 39.0 2.85e-01 86.7% 82.4%
8c92E01 3.40.1370.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L4; Chain: A; › Ribosomal protein L4/L1 0.51 40.0 3.02e-01 96.7% 92.4%
3kzpA00 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.51 37.0 2.67e-01 85.0% 68.0%
2uv4A00 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.51 41.0 3.31e-01 100.0% 63.6%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3278783 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 65.0 3.81e-01 100.0% 18.5%
3594922 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.72 64.0 4.85e-01 100.0% 51.4%
3955799 2004.1.1.364 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C 0.70 61.0 3.56e-01 98.3% 31.9%
3677754 2004.1.1.24 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C 0.67 59.0 3.40e-01 100.0% 20.0%
3601542 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 58.0 4.27e-01 100.0% 89.7%
5008886 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.66 48.0 3.75e-01 78.3% 77.7%
4265947 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.63 50.0 3.34e-01 91.7% 47.9%
None — 0.63 44.0 3.06e-01 75.0% 57.4%
3960047 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.61 51.0 3.63e-01 100.0% 59.5%
3604241 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.60 49.0 3.55e-01 98.3% 62.5%
4052375 7580.1.1.1 ↗ a/b three-layered sandwiches › RibA-like › RibA-like › RibA-like › GTP_cyclohydro2 0.60 44.0 3.33e-01 78.3% 43.3%
3797023 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 48.0 3.31e-01 98.3% 43.2%
3933477 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.59 47.0 3.50e-01 91.7% 81.8%
3618647 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.59 48.0 3.62e-01 98.3% 63.5%
3320511 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 48.0 3.17e-01 96.7% 36.6%
3274328 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.59 41.0 2.41e-01 73.3% 33.9%
3435952 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.57 48.0 3.23e-01 100.0% 63.0%
3280738 2007.1.4.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain 0.56 40.0 3.58e-01 78.3% 93.7%
4387146 7588.1.1.1 ↗ a/b three-layered sandwiches › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › LYTB 0.56 40.0 3.54e-01 80.0% 90.0%
4135988 7588.1.1.2 ↗ a/b three-layered sandwiches › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA 0.56 40.0 3.17e-01 81.7% 64.7%
3182438 7577.1.1.3 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.56 43.0 2.84e-01 95.0% 47.7%
3924124 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.54 44.0 2.93e-01 100.0% 23.4%
5066046 2003.1.1.22 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA 0.54 44.0 3.50e-01 98.3% 62.9%
4926812 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.53 42.0 3.01e-01 98.3% 62.1%
3922307 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.52 36.0 2.59e-01 73.3% 55.0%
3300451 2006.1.1.52 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › PF28688 0.52 42.0 3.28e-01 96.7% 64.5%
3937477 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.52 40.0 2.99e-01 100.0% 29.5%
3622047 7581.1.1.22 ↗ a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N, ketoacyl-synt 0.50 42.0 2.91e-01 100.0% 46.1%
D6 medium residues 544-616
PDB
Domain cluster: rep: large_T-antigen__YP_009508818__Erythrura_gouldiae_polyomavirus_1__2169903__D490-559
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 113.6 1.50e-32 100.0% 17.5%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1svmA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.95 91.0 6.83e-01 100.0% 47.7%
1tueD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.77 64.0 4.57e-01 100.0% 32.2%
1grlB01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.58 45.0 3.26e-01 89.0% 93.0%
6ks6a01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.56 43.0 3.05e-01 89.0% 87.0%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2482197 2004.1.1.142 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Polyoma_lg_T_C 0.95 91.0 7.19e-01 100.0% 55.7%
119334 4949.1.1.2 ↗ alpha complex topology › PsV capsid protein › PsV capsid protein › PsV capsid protein › PsV_CP_C 0.54 42.0 2.77e-01 89.0% 67.5%
3246217 214.1.1.1 ↗ a+b two layers › SH2 › SH2 › SH2 › SH2 0.54 37.0 3.09e-01 72.6% 91.1%
3517388 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 44.0 3.31e-01 100.0% 38.5%
3603411 192.2.1.2 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.50 39.0 3.30e-01 87.7% 51.1%
D7 medium residues 617-703
PDB
Domain cluster: rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D403-422_572-647
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06431.17 best Polyoma_lg_T_C 79.7 3.10e-22 97.7% 18.2%