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large_ribonuclease_reductase

Euk-Vir

Human_betaherpesvirus_6B

large_ribonuclease_reductase__NP_050209__Human_betaherpesvirus_6B__32604

Identity

Accession:
NP_050209 ↗
Protein ID:
large_ribonuclease_reductase
Kingdom:
euk

Quality

84.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_6B

TaxID: 32604

Cluster

View cluster (122 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 439-475_490-604
PDB
Domain cluster: rep: rr1__YP_009552690__Operophtera_brumata_nucleopolyhedrovirus__1046267__D445-618_684-706
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 65.6 5.10e-18 98.0% 23.1%
D2 high residues 638-769
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4x7rA03 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.57 32.0 2.92e-01 99.2% 42.0%
4pqgA03 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.54 31.0 2.83e-01 76.5% 42.5%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3495709 207.1.1.85 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › F-box-like 0.51 43.0 2.90e-01 93.2% 66.5%
D3 medium residues 17-113_140-182
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.55 44.0 4.04e-01 85.7% 93.7%
1rz4A01 1.25.40.250 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat; domain 1 0.55 40.0 4.29e-01 78.6% 88.3%
3rc3A05 1.20.58.1080 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 34.0 3.79e-01 75.0% 84.1%
5l0wB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 39.0 3.98e-01 82.1% 99.3%
1hu3A00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 41.0 3.62e-01 86.4% 72.5%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4203091 109.4.1.1694 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28753, PF28771 0.60 43.0 3.39e-01 73.6% 51.6%
3591136 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 39.0 3.62e-01 78.6% 100.0%
2104833 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 39.0 3.66e-01 82.1% 66.1%
3805103 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.50 33.0 3.70e-01 72.9% 87.6%
D4 medium residues 238-304
PDB
Domain cluster: representative
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tuiD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 63.0 4.28e-01 100.0% 48.3%
2bo4A01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.69 56.0 4.11e-01 100.0% 31.8%
3l77A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 60.0 4.16e-01 100.0% 39.6%
4akgA15 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 57.0 4.74e-01 100.0% 50.0%
1fnnA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 60.0 4.48e-01 100.0% 50.6%
5kivA01 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.67 59.0 4.29e-01 100.0% 77.2%
2ox6D00 1.10.3100.10 Mainly Alpha › Orthogonal Bundle › Putative cytoplasmic protein › Putative cytoplasmic protein 0.67 53.0 4.00e-01 86.6% 49.1%
2ymbA00 3.30.870.30 Alpha Beta › 2-Layer Sandwich › Endonuclease; Chain A › MITD, C-terminal phospholipase D-like domain 0.66 59.0 4.54e-01 100.0% 43.8%
7jpjB01 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.66 58.0 3.99e-01 100.0% 32.9%
3n74A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 57.0 4.00e-01 100.0% 55.1%
3mt1B02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.66 57.0 4.07e-01 100.0% 33.6%
3eccA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 56.0 4.23e-01 95.5% 85.8%
2cx6A00 3.30.370.10 Alpha Beta › 2-Layer Sandwich › Barnase; Chain D › Barstar-like 0.65 56.0 5.17e-01 98.5% 94.4%
2b99C00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.65 58.0 4.44e-01 100.0% 59.9%
7d73E01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.65 56.0 3.96e-01 100.0% 34.6%
3thxB05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 52.0 3.58e-01 100.0% 24.5%
7rheA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.64 54.0 4.13e-01 100.0% 87.4%
7c2gG01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.64 51.0 4.69e-01 88.1% 78.4%
1g6hA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 55.0 3.76e-01 100.0% 66.5%
1l8qA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 51.0 3.92e-01 92.5% 78.8%
3a32A01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.63 50.0 3.22e-01 86.6% 28.4%
1n2sA02 3.90.25.10 Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1 0.63 47.0 4.40e-01 82.1% 64.7%
4hlnA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.63 47.0 3.43e-01 100.0% 27.0%
3zs6A03 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.62 52.0 3.60e-01 91.0% 59.0%
2i9iA00 3.30.160.180 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Putative neuraminyllactose-binding hemagglutinin homolog like domain 0.62 48.0 3.33e-01 83.6% 87.3%
3rpjA00 3.30.310.230 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Sigma factor-binding protein Crl monomer 0.62 49.0 4.02e-01 88.1% 85.7%
7whfC02 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.62 51.0 4.50e-01 92.5% 79.0%
7dd0C01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 53.0 3.67e-01 98.5% 46.8%
3i3fB00 3.30.1330.40 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › RutC-like 0.61 53.0 4.37e-01 100.0% 61.7%
5bq5B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 50.0 3.73e-01 94.0% 65.8%
3tpaA03 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.61 51.0 3.59e-01 94.0% 57.3%
1nmnA00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.60 48.0 4.00e-01 88.1% 75.0%
4i1sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 48.0 4.12e-01 92.5% 81.0%
5f2hA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 50.0 3.71e-01 95.5% 86.1%
2bgwB01 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 50.0 4.15e-01 100.0% 51.9%
3i7tA00 3.30.1330.40 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › RutC-like 0.59 51.0 4.31e-01 100.0% 57.6%
1dljA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 49.0 3.52e-01 94.0% 47.1%
2xitA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 49.0 3.35e-01 100.0% 29.7%
6eudA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 50.0 3.80e-01 100.0% 60.8%
4inaA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 49.0 3.62e-01 100.0% 34.2%
3tm4A01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.57 48.0 3.63e-01 100.0% 46.0%
2y27A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.57 45.0 3.93e-01 85.1% 58.3%
6acsA00 3.40.1180.10 Alpha Beta › 3-Layer(aba) Sandwich › Undecaprenyl pyrophosphate synthetase › Decaprenyl diphosphate synthase-like 0.57 48.0 3.45e-01 100.0% 48.0%
3f67A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 50.0 3.44e-01 100.0% 36.3%
1m0wA04 3.40.50.1760 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glutathione synthase, substrate-binding domain superfamily, eukaryotic 0.57 43.0 3.54e-01 86.6% 43.4%
3bs4A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 49.0 3.38e-01 100.0% 26.9%
3hnoD02 3.40.50.460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphofructokinase domain 0.56 46.0 3.56e-01 100.0% 37.6%
2hpgC00 3.40.190.170 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 0.56 41.0 2.72e-01 80.6% 81.2%
3pbkA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.56 43.0 3.70e-01 85.1% 51.9%
4irxA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 47.0 3.65e-01 100.0% 68.3%
3wqlA01 3.40.1180.10 Alpha Beta › 3-Layer(aba) Sandwich › Undecaprenyl pyrophosphate synthetase › Decaprenyl diphosphate synthase-like 0.55 45.0 3.25e-01 100.0% 49.2%
3tnjA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 45.0 3.84e-01 100.0% 53.7%
4jj9C00 3.30.429.10 Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor 0.55 46.0 3.69e-01 98.5% 84.8%
3gkuC02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.54 43.0 4.01e-01 92.5% 78.7%
3myuA01 3.40.190.180 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Cypl, domain I 0.53 45.0 3.55e-01 97.0% 57.7%
6kwzA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.53 42.0 3.83e-01 94.0% 81.6%
3cs3A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 46.0 3.71e-01 100.0% 66.4%
6l1kA01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 42.0 3.24e-01 100.0% 57.2%
8dq6A01 3.30.429.10 Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor 0.51 42.0 3.81e-01 98.5% 100.0%
3bk2A03 3.10.20.580 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.50 41.0 3.66e-01 92.5% 72.7%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3961973 2002.1.2.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › Hypothetical protein Cthe_0052 0.72 63.0 4.50e-01 100.0% 44.0%
3786064 2004.1.1.189 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_16 0.70 61.0 4.44e-01 100.0% 55.4%
4979883 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.70 62.0 4.88e-01 100.0% 47.1%
5024633 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.70 56.0 4.46e-01 89.6% 47.1%
3408059 2496.1.1.2 ↗ a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.68 58.0 4.68e-01 100.0% 48.5%
3982647 2002.1.2.16 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › Hypothetical protein Cthe_0052 › DUF4434 0.68 58.0 4.40e-01 100.0% 48.6%
5078041 2004.1.1.161 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TmcA_N 0.68 55.0 4.00e-01 92.5% 32.5%
3284133 2496.1.1.2 ↗ a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.67 56.0 4.84e-01 100.0% 57.4%
347581 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.67 58.0 4.51e-01 98.5% 48.7%
4184305 2488.1.1.12 ↗ a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › Methyltrans_RNA 0.66 57.0 4.29e-01 100.0% 38.2%
4573327 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.66 58.0 4.45e-01 100.0% 62.9%
169836 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.66 54.0 4.23e-01 94.0% 51.9%
3568302 220.1.1.28 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › hSac2 0.66 55.0 4.06e-01 92.5% 70.0%
3595687 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.66 57.0 3.79e-01 98.5% 36.4%
4997440 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.66 54.0 4.48e-01 95.5% 51.5%
169538 2004.1.1.68 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IstB_IS21 0.66 56.0 4.10e-01 95.5% 76.4%
5048563 7515.1.1.2 ↗ a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase 0.65 55.0 3.34e-01 100.0% 46.7%
3806185 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.65 56.0 3.43e-01 100.0% 23.0%
5019274 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 55.0 4.23e-01 100.0% 68.2%
4281154 2004.1.1.191 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_17 0.65 51.0 3.78e-01 88.1% 83.2%
5076048 2006.1.4.55 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NRDD 0.64 54.0 3.87e-01 98.5% 48.6%
4118739 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.64 51.0 3.98e-01 86.6% 60.0%
3919864 7529.1.1.0 ↗ a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like 0.64 48.0 3.93e-01 86.6% 42.3%
1687981 7573.1.1.1 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran 0.64 49.0 4.38e-01 92.5% 58.3%
4424832 2004.1.1.45 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MutS_V 0.64 55.0 3.78e-01 100.0% 46.1%
5057709 2002.1.1.101 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Orn_Arg_deC_N 0.64 55.0 3.83e-01 100.0% 32.9%
5030937 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.63 54.0 3.59e-01 100.0% 56.6%
3610091 207.1.1.267 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › PF26020 0.63 52.0 3.63e-01 100.0% 27.5%
4425456 2004.1.1.68 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IstB_IS21 0.63 52.0 3.67e-01 94.0% 55.9%
3178454 131.1.1.27 ↗ alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › RTG2_C 0.63 49.0 3.53e-01 88.1% 93.8%
4881894 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.62 53.0 3.70e-01 100.0% 29.3%
3740596 2496.1.1.2 ↗ a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.62 51.0 3.69e-01 100.0% 45.7%
4559879 2484.1.1.40 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.62 49.0 3.92e-01 88.1% 62.9%
2330444 292.2.1.15 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › PF29923 0.61 53.0 4.36e-01 100.0% 72.3%
2142336 2004.1.1.35 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Bac_DnaA 0.61 47.0 3.74e-01 100.0% 37.9%
4011168 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 52.0 3.88e-01 100.0% 58.6%
4928434 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.60 53.0 3.95e-01 100.0% 39.1%
5040707 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.60 50.0 3.84e-01 95.5% 61.2%
3585293 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.60 50.0 3.71e-01 98.5% 38.5%
4947491 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.59 53.0 4.04e-01 100.0% 62.5%
3597422 7574.1.1.0 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.59 51.0 3.76e-01 100.0% 78.9%
3630889 7512.1.1.12 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_tran_28_C 0.59 49.0 3.68e-01 100.0% 34.9%
4466448 7590.1.1.0 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.59 51.0 3.66e-01 100.0% 56.2%
3243551 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.59 51.0 3.69e-01 100.0% 34.0%
4000045 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.59 50.0 3.73e-01 100.0% 35.8%
4113651 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 45.0 4.04e-01 88.1% 100.0%
2488644 2005.1.1.15 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP-sulfurylase 0.58 49.0 4.05e-01 95.5% 53.7%
3926777 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.58 49.0 3.78e-01 100.0% 66.1%
5059125 247.1.1.11 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.58 48.0 3.36e-01 100.0% 94.5%
3218392 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.57 46.0 3.02e-01 92.5% 23.9%
4538254 4143.1.1.1 ↗ a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like › THUMP 0.57 48.0 4.18e-01 100.0% 79.1%
4162427 2484.1.1.25 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC 0.56 46.0 3.65e-01 97.0% 61.3%
3630274 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.56 48.0 3.54e-01 100.0% 48.2%
3925211 327.11.1.4 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › MRP-S24 0.56 46.0 3.66e-01 91.0% 45.7%
3960977 246.1.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.55 46.0 3.37e-01 100.0% 70.2%
3999486 2496.1.1.0 ↗ a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like 0.55 46.0 4.14e-01 100.0% 89.0%
4830454 2004.1.1.73 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.54 47.0 3.93e-01 100.0% 93.5%
4322703 2004.1.1.334 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 44.0 3.35e-01 100.0% 37.1%
4037140 327.11.1.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.52 40.0 3.56e-01 94.0% 57.0%
D5 medium residues 305-416
PDB
Domain cluster: rep: ribonucleotide-diphosphate_reductase_large_chain__YP_009119180__Pandoravirus_inopinatum__1605721__D783-936