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large_subunit_of_mRNA_capping_enzyme

Euk-Vir

Vaccinia_virus

large_subunit_of_mRNA_capping_enzyme__YP_232988__Vaccinia_virus__10245

Identity

Accession:: YP_232988 ↗
Protein ID:: large_subunit_of_mRNA_capping_enzyme
Kingdom:: euk

Quality

83.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Orthopoxvirus_vaccinia

TaxID: 10245

Cluster

View cluster (35 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 238-393

PDB

Domain cluster: rep: Salt_Pond_R1_B_H2O_MG_scaffold_1_prodigal-single.1__X__X__00295__D161-347

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF21004.4 best	MCEL_GT_NTPase	130.8	2.60e-38	64.7%	88.5%

D2 high residues 403-508

PDB

Domain cluster: rep: putative_D1R_protein__YP_010085774__Orthopoxvirus_Abatino__2478919__D399-522

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF21005.5 best	OB_MCEL_GT	171.7	1.30e-50	100.0%	76.1%

D3 medium residues 12-27_152-167_192-226

PDB

Domain cluster: representative

CATH (15)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
8be0A01	3.40.91.90	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain	0.61	41.0	2.94e-01	70.1%	30.9%
3aeiA00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.57	38.0	3.43e-01	94.0%	50.0%
6fdmA02	1.10.510.10	Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1	0.57	49.0	4.21e-01	100.0%	67.3%
1emsA02	3.30.428.10	Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like	0.56	41.0	3.30e-01	74.6%	49.2%
4bqqB02	3.90.1750.20	Alpha Beta › Alpha-Beta Complex › Hect, E3 ligase catalytic domain fold › Putative Large Serine Recombinase; Chain B, Domain 2	0.54	38.0	2.87e-01	77.6%	71.6%
4q7qB00	3.40.50.1110	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase	0.54	48.0	3.22e-01	100.0%	70.0%
3a7rA01	3.30.930.10	Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2	0.53	45.0	3.14e-01	100.0%	85.9%
5cs2A00	3.30.428.10	Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like	0.52	37.0	2.96e-01	76.1%	59.9%
3bqkA02	1.20.1310.20	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain	0.52	46.0	3.55e-01	100.0%	65.2%
7wa9A01	3.30.530.20	Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain	0.51	39.0	3.11e-01	83.6%	95.0%
3cedA00	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.51	35.0	3.18e-01	73.1%	77.6%
3lxqA01	3.30.1120.80	Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain ›	0.51	43.0	3.82e-01	94.0%	82.8%
3v2uC02	3.30.70.3170	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.51	38.0	3.46e-01	83.6%	86.3%
3oqbH02	3.30.360.10	Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2	0.50	36.0	2.50e-01	76.1%	47.5%
2zdiB00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.50	37.0	3.23e-01	100.0%	50.9%

ECOD (15)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1147806	868.1.1.7 ↗	a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › MCEL_TPase	0.96	90.0	5.96e-01	97.0%	95.0%
3245872	2008.1.1.24 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDCD9	0.61	44.0	2.71e-01	76.1%	68.0%
4940192	192.2.1.1 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2	0.60	38.0	3.21e-01	92.5%	38.6%
5003874	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.60	38.0	3.16e-01	98.5%	35.8%
3797423	3226.1.1.0 ↗	alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA	0.57	47.0	2.86e-01	94.0%	65.1%
3291029	2003.1.3.6 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › Pyr_redox_3	0.57	47.0	3.33e-01	94.0%	95.9%
3379432	7512.1.1.66 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Exostosin_GT47	0.56	39.0	2.78e-01	76.1%	47.6%
3638947	244.1.1.9 ↗	a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › GMC_oxred_C	0.55	41.0	2.82e-01	80.6%	31.6%
3509920	3012.1.1.5 ↗	a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › T6PP_C	0.55	38.0	3.51e-01	73.1%	72.2%
3735230	633.23.1.0 ↗	alpha bundles › Bromodomain-like › Claudin › Claudin	0.55	38.0	2.86e-01	71.6%	45.2%
3970038	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.54	32.0	2.84e-01	94.0%	38.4%
3165049	3218.1.1.0 ↗	a+b duplicates or obligate multimers › small terminase oligomerization domain › small terminase oligomerization domain › small terminase oligomerization domain	0.53	36.0	3.72e-01	71.6%	90.8%
3622876	3651.1.1.0 ↗	alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain	0.51	37.0	2.93e-01	74.6%	54.1%
3293986	2004.1.1.159 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M	0.51	43.0	2.76e-01	94.0%	47.0%
4350626	3681.1.1.0 ↗	a+b complex topology › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit	0.50	35.0	2.88e-01	73.1%	50.0%

D4 medium residues 28-151_168-191

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF10640.15 best	MCEL_TPase	196.3	5.40e-58	84.5%	62.1%

CATH (11)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4ckbD02	3.20.100.20	Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A ›	0.95	92.0	8.04e-01	100.0%	78.0%
3bgyA00	3.20.100.10	Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › mRNA triphosphatase Cet1-like	0.72	68.0	5.80e-01	100.0%	81.0%
1yemB00	2.40.320.10	Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001	0.63	51.0	4.90e-01	94.6%	74.7%
7cayA01	2.30.130.40	Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like	0.55	32.0	3.77e-01	82.4%	84.0%
2aneH00	2.30.130.40	Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like	0.54	33.0	3.80e-01	81.1%	82.6%
4z85A00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.53	37.0	3.39e-01	71.6%	84.3%
6vbkA01	2.30.130.40	Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like	0.51	32.0	3.66e-01	82.4%	83.8%
1v8cA02	3.30.1370.80	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain	0.51	28.0	3.73e-01	97.3%	100.0%
3bpkA01	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.50	39.0	3.68e-01	81.1%	97.8%
1zboA01	2.30.130.40	Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like	0.50	32.0	3.62e-01	83.1%	83.2%
5choF00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.50	35.0	3.47e-01	71.6%	94.4%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1147806	868.1.1.7 ↗	a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › MCEL_TPase	0.94	92.0	7.81e-01	100.0%	73.9%
4026514	868.1.1.2 ↗	a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA_triPase	0.67	63.0	5.11e-01	100.0%	71.5%
3694694	868.1.1.5 ↗	a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › Med18	0.62	54.0	4.62e-01	94.6%	80.8%
3820214	1.1.9.5 ↗	beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg	0.59	35.0	3.07e-01	83.1%	40.0%
4358643	1.1.9.5 ↗	beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg	0.55	35.0	3.08e-01	75.7%	42.3%
3389361	1.1.7.0 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C	0.54	27.0	3.33e-01	83.8%	74.7%
4672795	304.8.1.0 ↗	a+b two layers › Alpha-beta plaits › ACT-like › ACT-like	0.51	25.0	3.38e-01	98.0%	90.7%

D5 medium residues 544-713_766-789

PDB

Domain cluster: rep: IMGVR_UViG_3300009616_000257-3300009616-Ga0116111_100275611__D486-632

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03291.23 best	mRNA_G-N7_MeTrfase	59.9	3.30e-16	89.7%	46.0%

D6 medium residues 714-765_790-844

PDB

Domain cluster: rep: mRNA_capping_enzyme_large_subunit__YP_009408284__Murmansk_poxvirus__2025359__D708-760_793-839