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late_expression_factor_4

Euk-Vir

Malacosoma_neustria_nucleopolyhedrovirus

late_expression_factor_4__YP_009552205__Malacosoma_neustria_nucleopolyhedrovirus__38012

Identity

Accession:
YP_009552205 ↗
Protein ID:
late_expression_factor_4
Kingdom:
euk

Quality

81.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 211-400
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 238.8 1.80e-70 100.0% 40.0%
D2 high residues 404-455
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 38.8 8.70e-10 100.0% 11.2%
D3 medium residues 1-10_35-107_124-149
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 81.2 1.20e-22 100.0% 26.2%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4f0qD01 2.30.280.20 Mainly Beta › Roll › PUA domain-like › 0.56 38.0 2.94e-01 70.6% 47.1%
4hudA01 3.30.2000.40 Alpha Beta › 2-Layer Sandwich › STM4215-like › Myoviridae tail sheath stabiliser 0.51 38.0 3.04e-01 76.1% 52.9%
1rtzA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.51 36.0 3.22e-01 77.1% 52.0%
3rt0C00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 37.0 3.17e-01 76.1% 79.7%
1jw3A00 3.55.10.10 Alpha Beta › 3-Layer(bab) Sandwich › Archease, Possible Chaperone; Chain: A; domain 1 › Archease domain 0.50 41.0 3.75e-01 93.6% 67.9%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3609931 868.1.1.2 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA_triPase 0.77 59.0 4.50e-01 78.9% 70.0%
4372267 868.1.1.2 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA_triPase 0.77 71.0 5.01e-01 97.2% 69.6%
3599391 868.1.1.2 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA_triPase 0.66 60.0 4.66e-01 96.3% 68.5%
4029744 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.59 43.0 3.93e-01 76.1% 86.2%
4988254 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.58 42.0 3.56e-01 76.1% 67.2%
5027270 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.57 42.0 3.55e-01 76.1% 71.4%
3587593 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.56 35.0 4.03e-01 76.1% 86.3%
3972051 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 36.0 3.40e-01 77.1% 54.6%
3603456 304.8.1.82 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › PF27325 0.54 36.0 3.95e-01 75.2% 81.1%
3946057 304.102.1.1 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_2 0.54 40.0 3.10e-01 76.1% 43.5%
2892215 5091.1.1.1 beta sandwiches › VP4 membrane interaction domain › VP4 membrane interaction domain › VP4 membrane interaction domain › Rota_VP4_MID 0.54 42.0 3.26e-01 82.6% 51.1%
4964127 331.3.1.11 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.54 39.0 3.39e-01 76.1% 91.2%
4953567 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.53 32.0 3.71e-01 76.1% 83.7%
5024124 304.15.1.0 a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.51 32.0 3.61e-01 76.1% 83.7%
3719492 304.102.1.1 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_2 0.51 39.0 2.82e-01 79.8% 46.8%
5040331 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.51 37.0 3.39e-01 75.2% 73.8%
5052888 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.51 39.0 3.73e-01 80.7% 77.6%
3496425 12.1.1.0 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.50 34.0 3.08e-01 82.6% 50.7%
D4 medium residues 11-34_108-123_164-203
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 32.8 5.90e-08 56.2% 8.9%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2eenA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.68 59.0 4.50e-01 93.8% 88.1%
2qrdA00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.68 58.0 5.16e-01 95.0% 94.7%
1kfiA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.67 58.0 5.02e-01 97.5% 90.4%
4hjhA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.66 59.0 5.48e-01 100.0% 92.1%
2mj7A00 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.64 56.0 4.74e-01 100.0% 66.0%
8es5A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.64 56.0 4.74e-01 100.0% 89.9%
2il5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.63 53.0 4.37e-01 100.0% 90.1%
1vx7H01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.62 52.0 5.17e-01 100.0% 88.2%
4g3wA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.61 48.0 4.10e-01 87.5% 100.0%
2wqlA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.61 52.0 4.34e-01 100.0% 92.8%
2rrnA01 3.30.70.2040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 45.0 4.50e-01 97.5% 78.3%
2qpvA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.59 50.0 4.36e-01 100.0% 93.2%
5ja2A01 3.30.559.30 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Nonribosomal peptide synthetase, condensation domain 0.58 51.0 3.63e-01 100.0% 73.6%
4gw9A01 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.58 45.0 3.43e-01 88.7% 78.6%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 47.0 4.61e-01 100.0% 86.2%
7r3eB02 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.57 46.0 3.68e-01 88.7% 90.2%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.57 49.0 4.73e-01 100.0% 89.5%
6cc0A01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.57 45.0 3.64e-01 88.7% 92.1%
4oyvA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.55 44.0 3.76e-01 90.0% 76.8%
4isbB02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.54 42.0 3.89e-01 92.5% 65.4%
4gs5A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.54 42.0 3.89e-01 93.8% 66.7%
6wqbA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.53 40.0 3.38e-01 82.5% 67.6%
2l8oA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 45.0 3.85e-01 100.0% 89.6%
3l1aA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.53 44.0 3.33e-01 97.5% 52.3%
4gb7A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.53 44.0 2.88e-01 95.0% 87.6%
2q3fA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 41.0 3.22e-01 86.3% 78.8%
5lp7E01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.52 37.0 2.81e-01 75.0% 91.6%
2jgpA02 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.52 44.0 3.43e-01 100.0% 75.0%
2wweA01 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.52 43.0 4.05e-01 97.5% 96.2%
5t3dA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.51 43.0 3.48e-01 98.8% 73.7%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3594390 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.70 62.0 5.57e-01 97.5% 96.4%
4982514 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.68 54.0 5.57e-01 100.0% 92.0%
5030737 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.68 60.0 5.80e-01 98.8% 90.0%
5073891 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.66 57.0 5.38e-01 100.0% 98.0%
3970706 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.66 58.0 4.98e-01 100.0% 87.7%
3875765 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.66 41.0 2.66e-01 88.7% 15.2%
4182456 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.63 54.0 5.34e-01 98.8% 91.8%
3937269 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.63 52.0 4.10e-01 96.2% 50.3%
4965204 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.62 51.0 4.50e-01 91.3% 72.5%
3230613 3755.3.1.410 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Nup88 0.61 36.0 2.15e-01 90.0% 8.4%
4332439 304.28.1.2 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG 0.59 44.0 4.31e-01 100.0% 72.2%
3784643 318.1.1.0 a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 0.59 50.0 4.66e-01 96.2% 94.2%
3835676 314.1.1.9 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_His 0.59 48.0 3.70e-01 93.8% 70.5%
3340180 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.59 50.0 4.72e-01 98.8% 84.0%
4469636 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.57 46.0 4.52e-01 100.0% 83.5%
3688597 2011.2.1.0 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like 0.56 38.0 2.91e-01 75.0% 29.3%
4936431 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.56 39.0 4.01e-01 97.5% 80.0%
4888514 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.55 34.0 2.45e-01 73.8% 21.9%
5013584 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.55 43.0 4.53e-01 96.2% 100.0%
4888517 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.55 35.0 2.89e-01 72.5% 34.9%
4141464 4099.1.1.22 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › CENP-P 0.54 43.0 3.95e-01 90.0% 87.3%
1155906 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.54 42.0 3.89e-01 93.8% 66.7%
4999507 330.7.1.2 a+b two layers › dsRBD-like › PI-Pfui intein middle domain › PI-Pfui intein middle domain › HicA_toxin 0.53 42.0 4.41e-01 92.5% 100.0%
142587 331.3.1.9 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AHSA1 0.53 45.0 3.91e-01 100.0% 94.9%
5061016 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.53 45.0 3.28e-01 93.8% 82.5%
1117773 1.1.13.24 beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › DTP-pb9_A-dom_C,DTP-pb9_A-dom_N 0.53 38.0 4.05e-01 83.7% 92.5%
3958367 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.53 34.0 3.77e-01 87.5% 94.5%
3574409 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.52 40.0 3.85e-01 82.5% 77.8%
4398495 109.21.1.8 alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › WD40 0.52 40.0 2.33e-01 82.5% 33.6%
3960561 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.52 44.0 3.81e-01 96.2% 93.8%
4980950 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.52 42.0 4.09e-01 95.0% 83.2%
3944725 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.51 37.0 3.52e-01 92.5% 61.9%
3177260 292.2.1.1 a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › POLO_box 0.51 42.0 3.07e-01 92.5% 96.2%
4955569 873.1.1.1 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › V4R 0.51 40.0 3.20e-01 88.7% 53.7%
4034385 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.51 45.0 4.06e-01 100.0% 76.4%
3960051 327.5.1.3 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_2 0.51 41.0 3.74e-01 95.0% 65.5%
3691059 844.1.1.0 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain 0.50 42.0 3.38e-01 95.0% 95.9%